GB2089341B - Buspirone process - Google Patents

Buspirone process

Info

Publication number
GB2089341B
GB2089341B GB8132370A GB8132370A GB2089341B GB 2089341 B GB2089341 B GB 2089341B GB 8132370 A GB8132370 A GB 8132370A GB 8132370 A GB8132370 A GB 8132370A GB 2089341 B GB2089341 B GB 2089341B
Authority
GB
United Kingdom
Prior art keywords
buspirone
buspirone process
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB8132370A
Other languages
English (en)
Other versions
GB2089341A (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Co
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of GB2089341A publication Critical patent/GB2089341A/en
Application granted granted Critical
Publication of GB2089341B publication Critical patent/GB2089341B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/20—Spiro-condensed ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/30—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/34—One oxygen atom
    • C07D239/36—One oxygen atom as doubly bound oxygen atom or as unsubstituted hydroxy radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
GB8132370A 1980-12-11 1981-10-27 Buspirone process Expired GB2089341B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US21521480A 1980-12-11 1980-12-11

Publications (2)

Publication Number Publication Date
GB2089341A GB2089341A (en) 1982-06-23
GB2089341B true GB2089341B (en) 1984-09-19

Family

ID=22802113

Family Applications (1)

Application Number Title Priority Date Filing Date
GB8132370A Expired GB2089341B (en) 1980-12-11 1981-10-27 Buspirone process

Country Status (18)

Country Link
JP (1) JPS57122082A (de)
AT (1) AT380686B (de)
AU (1) AU528067B2 (de)
BE (1) BE891446A (de)
CA (1) CA1172255A (de)
CH (1) CH647518A5 (de)
DE (1) DE3149011A1 (de)
DK (1) DK154560C (de)
FI (1) FI73993C (de)
FR (1) FR2496105B1 (de)
GB (1) GB2089341B (de)
GR (1) GR76331B (de)
IE (1) IE51948B1 (de)
IT (1) IT1172073B (de)
LU (1) LU83833A1 (de)
NL (1) NL8105529A (de)
SE (1) SE444438B (de)
YU (1) YU42432B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU212301B (en) * 1989-04-28 1996-05-28 Alkaloida Vegyeszeti Gyar Process for producing buspirone
US5484788A (en) * 1993-03-26 1996-01-16 Beth Israel Hospital Association Buspirone as a systemic immunosuppressant
US5631017A (en) * 1993-03-26 1997-05-20 Beth Israel Deaconess Medical Center, Inc. Topical application of buspirone for treatment of pathological conditions associated with immune responses
KR950014099A (ko) * 1993-11-10 1995-06-15 장기하 N-(2-피리미딜)피페라지닐 부틸아미드의 제조방법
US5637314A (en) * 1995-06-07 1997-06-10 Beth Israel Deaconess Medical Center, Inc. Topical and systemic application of buspirone or derivatives thereof for treating atopic dermatitis

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE759371A (fr) * 1969-11-24 1971-05-24 Bristol Myers Co Azaspirodecanediones heterocycliques et procedes pour leur preparation
DE2341925A1 (de) * 1973-08-20 1975-03-06 Thomae Gmbh Dr K Neue pyrimidinderivate und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
JPH0113476B2 (de) 1989-03-06
IE51948B1 (en) 1987-04-29
FI813937L (fi) 1982-06-12
DE3149011C2 (de) 1988-08-25
SE444438B (sv) 1986-04-14
IE812897L (en) 1982-06-11
SE8107446L (sv) 1982-06-12
FR2496105A1 (fr) 1982-06-18
DK154560B (da) 1988-11-28
FI73993B (fi) 1987-08-31
YU42432B (en) 1988-08-31
GR76331B (de) 1984-08-04
ATA529581A (de) 1985-11-15
FR2496105B1 (fr) 1985-12-13
DE3149011A1 (de) 1982-07-15
CH647518A5 (de) 1985-01-31
DK154560C (da) 1989-04-17
CA1172255A (en) 1984-08-07
JPS57122082A (en) 1982-07-29
AT380686B (de) 1986-06-25
DK548081A (da) 1982-06-12
GB2089341A (en) 1982-06-23
AU7604181A (en) 1982-07-15
IT1172073B (it) 1987-06-18
BE891446A (fr) 1982-06-11
NL8105529A (nl) 1982-07-01
IT8149718A0 (it) 1981-11-16
FI73993C (fi) 1987-12-10
AU528067B2 (en) 1983-04-14
YU243681A (en) 1984-02-29
LU83833A1 (fr) 1982-07-07

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Legal Events

Date Code Title Description
PE20 Patent expired after termination of 20 years

Effective date: 20011026