GB208145A - Improvements in process for obtaining certain remedial principles of oils - Google Patents
Improvements in process for obtaining certain remedial principles of oilsInfo
- Publication number
- GB208145A GB208145A GB30362/23A GB3036223A GB208145A GB 208145 A GB208145 A GB 208145A GB 30362/23 A GB30362/23 A GB 30362/23A GB 3036223 A GB3036223 A GB 3036223A GB 208145 A GB208145 A GB 208145A
- Authority
- GB
- United Kingdom
- Prior art keywords
- oils
- soaps
- extracted
- fish
- principle
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/07—Retinol compounds, e.g. vitamin A
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Fats And Perfumes (AREA)
- Edible Oils And Fats (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
The antirachitic principle of oils is extracted by treating the oil with 95 per cent alcohol or other neutral organic solvent, precipitating the free fatty acids also dissolved as insoluble soaps, such as those of the alkaline earth metals, and dissolving out the active principle from the precipitate by means of a solvent such as acetone. According to the example, cod-liver oil is extracted with 95 per cent alcohol, sodium hydroxide then added to form the sodium soaps of the free fatty acids present, the insoluble calcium soaps precipitated by the addition of calcium chloride and the soaps finally treated with acetone. Further purification is effected by extracting the concentrated acetone solution with ether, washing the ether extract with dilute alkali and acid, and distilling to obtain the active principle as a brown waxy material. Other fish-liver oils and fish-oils such as Menhaden oils may also be used. Specification 3075/15 is referred to. The Specification as open to inspection under Sect. 91 (3) (a) describes also a modified process in which the whole of the oil is first saponified with alcoholic sodium hydroxide and the products dissolved in water; the solution is then either extracted with ether, the extract dissolved in alcohol and evaporated to crystallize out the cholesterol, the remainder containing the antirachitic principle or alternatively, calcium chloride is added to precipitate the calcium soaps, which are extracted with alcohol and the dissolved cholesterol removed from the antirachitic principle by crystallization. Besides fish oils and fish-liver oils, vegetable oils may also be treated. This subject-matter does not appear in the Specification as accepted.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US208145XA | 1922-12-07 | 1922-12-07 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB208145A true GB208145A (en) | 1925-04-03 |
Family
ID=21800729
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB30362/23A Expired GB208145A (en) | 1922-12-07 | 1923-12-03 | Improvements in process for obtaining certain remedial principles of oils |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB208145A (en) |
-
1923
- 1923-12-03 GB GB30362/23A patent/GB208145A/en not_active Expired
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