GB2054371B - Long-acting parenteral compositions of haloperidol and bromperidol derivatives - Google Patents

Long-acting parenteral compositions of haloperidol and bromperidol derivatives

Info

Publication number
GB2054371B
GB2054371B GB8018117A GB8018117A GB2054371B GB 2054371 B GB2054371 B GB 2054371B GB 8018117 A GB8018117 A GB 8018117A GB 8018117 A GB8018117 A GB 8018117A GB 2054371 B GB2054371 B GB 2054371B
Authority
GB
United Kingdom
Prior art keywords
bromperidol
haloperidol
derivatives
long
parenteral compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB8018117A
Other languages
English (en)
Other versions
GB2054371A (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Pharmaceutica NV
Original Assignee
Janssen Pharmaceutica NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica NV filed Critical Janssen Pharmaceutica NV
Publication of GB2054371A publication Critical patent/GB2054371A/en
Application granted granted Critical
Publication of GB2054371B publication Critical patent/GB2054371B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/52—Oxygen atoms attached in position 4 having an aryl radical as the second substituent in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Anesthesiology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
GB8018117A 1979-06-28 1980-06-03 Long-acting parenteral compositions of haloperidol and bromperidol derivatives Expired GB2054371B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP8082679A JPS568318A (en) 1979-06-28 1979-06-28 Non oral long acting composition of haloperidol and bromperidol derivative

Publications (2)

Publication Number Publication Date
GB2054371A GB2054371A (en) 1981-02-18
GB2054371B true GB2054371B (en) 1983-08-03

Family

ID=13729223

Family Applications (1)

Application Number Title Priority Date Filing Date
GB8018117A Expired GB2054371B (en) 1979-06-28 1980-06-03 Long-acting parenteral compositions of haloperidol and bromperidol derivatives

Country Status (9)

Country Link
JP (1) JPS568318A (enrdf_load_stackoverflow)
BE (1) BE883994A (enrdf_load_stackoverflow)
CY (1) CY1255A (enrdf_load_stackoverflow)
DE (1) DE3024305A1 (enrdf_load_stackoverflow)
FR (1) FR2460932A1 (enrdf_load_stackoverflow)
GB (1) GB2054371B (enrdf_load_stackoverflow)
HK (1) HK83384A (enrdf_load_stackoverflow)
KE (1) KE3427A (enrdf_load_stackoverflow)
NL (1) NL190775C (enrdf_load_stackoverflow)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8621892D0 (en) * 1986-09-11 1986-10-15 Lundbeck & Co As H Organic compound
DK238190D0 (da) * 1990-10-03 1990-10-03 Lundbeck & Co As H Depotderivater
ES2077547T3 (es) * 1992-11-17 2000-06-16 Yoshitomi Pharmaceutical Microesfera de liberacion sostenida que contiene un antipsicotico y procedimiento de produccion.
WO1998018769A1 (en) * 1996-10-31 1998-05-07 The United States Of America, Represented By The Secretary, Department Of Health And Human Services Sustained-release derivatives of hydroxylated analogs of substituted 1-[2[bis(aryl)methoxy]ethyl]-piperazines and -homopiperazines and their use as noncompetitive antagonists of dopamine reuptake
RU2178297C1 (ru) * 2001-02-02 2002-01-20 Открытое акционерное общество "Химико-фармацевтический комбинат "Акрихин" Фармацевтическая композиция, обладающая антипсихотическим и противорвотным действием, и способ ее получения
BRPI0517701A8 (pt) 2004-11-10 2018-01-23 Genzyme Corp métodos de tratamento de diabetes mellitus
PT2032134E (pt) 2006-05-09 2015-10-07 Genzyme Corp Métodos de tratamento da doença do fígado gorduroso
EP2594563B1 (en) 2007-05-31 2018-07-18 Genzyme Corporation 2-acylaminopropanol-type glucosylceramide synthase inhibitors
WO2009045503A1 (en) 2007-10-05 2009-04-09 Genzyme Corporation Method of treating polycystic kidney diseases with ceramide derivatives
EP2320886B1 (en) 2008-07-28 2017-06-28 Genzyme Corporation Glucosylceramide synthase inhibition for the treatment of collapsing glomerulopathy and other glomerular disease
KR101687039B1 (ko) 2008-10-03 2016-12-15 젠자임 코포레이션 2-아실아미노프로판올형 글루코실세라미드 합성효소 억제제
DK3156056T3 (da) 2011-03-18 2024-02-26 Alkermes Pharma Ireland Ltd Farmaceutiske sammensætninger der består af sorbitanestere
CN103301461B (zh) * 2012-03-08 2018-09-07 江苏豪森药业集团有限公司 一种长效注射制剂及其制备方法和用途
JP6333802B2 (ja) 2012-03-19 2018-05-30 アルカームス ファーマ アイルランド リミテッド ベンジルアルコールを含む医薬組成物
ES2764383T3 (es) 2012-03-19 2020-06-03 Alkermes Pharma Ireland Ltd Composiciones farmacéuticas que comprenden ésteres de glicerol
NZ630643A (en) 2012-03-19 2017-08-25 Alkermes Pharma Ireland Ltd Pharmaceutical compositions comprising fatty acid esters
US9193685B2 (en) 2012-09-19 2015-11-24 Alkermes Pharma Ireland Limited Pharmaceutical compositions having improved storage stability
JP6524110B2 (ja) 2014-03-20 2019-06-05 アルカームス ファーマ アイルランド リミテッド 注射速度が増大したアリピプラゾール調合物
JP7384812B2 (ja) 2018-03-05 2023-11-21 アルカームス ファーマ アイルランド リミテッド アリピプラゾール投与戦略
CN113117092A (zh) * 2020-01-14 2021-07-16 中国科学院上海药物研究所 一种非水缓释递药系统
HUP2100259A1 (hu) 2021-07-07 2023-01-28 Richter Gedeon Nyrt Cariprazine tartalmú szabályozott hatóanyag-leadású injekciós készítmények

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3408356A (en) * 1965-08-31 1968-10-29 Squibb & Sons Inc Long chain esters of 4'-fluoro-4-[4-hydroxy-4-(alpha, alpha, alpha-trifluorotolyl)piperi-dino]butyrophenone and the like
DE1695194A1 (de) * 1966-07-11 1971-03-18 Hoffmann La Roche Verfahren zur Herstellung von Piperidinderivaten
US3850935A (en) * 1971-10-16 1974-11-26 Sumitomo Chemical Co Process for producing piperidine derivatives by degrading quaternary piperidinium salts

Also Published As

Publication number Publication date
CY1255A (en) 1984-08-31
HK83384A (en) 1984-11-09
FR2460932A1 (fr) 1981-01-30
NL190775C (nl) 1994-08-16
JPS568318A (en) 1981-01-28
NL8003583A (nl) 1980-12-30
GB2054371A (en) 1981-02-18
BE883994A (fr) 1980-12-29
DE3024305A1 (de) 1981-01-22
FR2460932B1 (enrdf_load_stackoverflow) 1984-11-16
NL190775B (nl) 1994-03-16
KE3427A (en) 1984-08-10
DE3024305C2 (enrdf_load_stackoverflow) 1989-12-07

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Legal Events

Date Code Title Description
PE20 Patent expired after termination of 20 years

Effective date: 20000602