GB2021946A - Pharmaceutical Formulations Containing Cis-platinum (II) Diamminedichloride - Google Patents

Pharmaceutical Formulations Containing Cis-platinum (II) Diamminedichloride

Info

Publication number
GB2021946A
GB2021946A GB7903379A GB7903379A GB2021946A GB 2021946 A GB2021946 A GB 2021946A GB 7903379 A GB7903379 A GB 7903379A GB 7903379 A GB7903379 A GB 7903379A GB 2021946 A GB2021946 A GB 2021946A
Authority
GB
United Kingdom
Prior art keywords
diamminedichloride
platinum
pharmaceutical formulations
formulations containing
containing cis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
GB7903379A
Other versions
GB2021946B (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Co
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application granted granted Critical
Publication of GB2021946B publication Critical patent/GB2021946B/en
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of GB2021946A publication Critical patent/GB2021946A/en
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/243—Platinum; Compounds thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

A stable, sterile aqueous solution of cis-platinum (II) diamminedichloride (cisplatin) in a sealed container such as an ampule or vial in unit dosage form suitable for intravenous administration to man has a concentration of cisplatin in the range of from 0.1 to 1.0 mgm/ml. and a pH in the range of from 2.0 to 3.0, preferably about 5.5. The solution can also contain sodium chloride and mannitol.
GB7903379A 1978-05-30 1979-01-31 Pharmaceutical Formulations Containing Cis-platinum (II) Diamminedichloride Expired - Lifetime GB2021946A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US91032578A 1978-05-30 1978-05-30

Publications (2)

Publication Number Publication Date
GB2021946B GB2021946B (en) 1900-01-01
GB2021946A true GB2021946A (en) 1979-12-12

Family

ID=25428626

Family Applications (1)

Application Number Title Priority Date Filing Date
GB7903379A Expired - Lifetime GB2021946A (en) 1978-05-30 1979-01-31 Pharmaceutical Formulations Containing Cis-platinum (II) Diamminedichloride

Country Status (32)

Country Link
JP (1) JPS54157817A (en)
AR (1) AR218134A1 (en)
AT (1) AT362052B (en)
AU (1) AU519873B2 (en)
BE (1) BE874596A (en)
CA (1) CA1119954A (en)
CH (1) CH619141A5 (en)
CS (1) CS226002B2 (en)
CY (1) CY1159A (en)
DD (1) DD142293A5 (en)
DE (1) DE2906700C2 (en)
DK (1) DK149192C (en)
ES (1) ES478272A1 (en)
FI (1) FI66121C (en)
FR (1) FR2427097A1 (en)
GB (1) GB2021946A (en)
HK (1) HK37982A (en)
HU (1) HU177557B (en)
IE (1) IE48177B1 (en)
IL (1) IL56540A (en)
IT (1) IT1116893B (en)
KE (1) KE3230A (en)
LU (1) LU81056A1 (en)
MY (1) MY8300152A (en)
NL (1) NL191108C (en)
NO (1) NO149914C (en)
NZ (1) NZ189556A (en)
PH (1) PH18056A (en)
PT (1) PT69207A (en)
SE (1) SE445172B (en)
SU (1) SU1192596A3 (en)
ZA (1) ZA79395B (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0041792A1 (en) * 1980-06-11 1981-12-16 Kureha Kagaku Kogyo Kabushiki Kaisha Platinum compounds having antitumor or antimicrobial activity, and pharmaceutical preparations containing them
DE3112272A1 (en) * 1980-03-31 1982-04-29 Bristol Myers Co PHARMACEUTICAL AGENT
FR2533439A1 (en) * 1982-09-23 1984-03-30 Erba Farmitalia NOVEL PHARMACEUTICAL COMPOSITIONS BASED ON CIS-PLATINUM-II-DIAMMINO-DICHLORIDE AND PROCESS FOR PREPARING THE SAME
EP0143478A1 (en) * 1983-10-24 1985-06-05 Pharmachemie B.V. Stable, aqueous, acidic solution of cis-platinum, suitable for injection
EP0334551A1 (en) * 1988-03-20 1989-09-27 Abic Limited Anti-neoplastic formulations

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4302446A (en) * 1979-10-02 1981-11-24 Bristol-Myers Company Pharmaceutical compositions
DE3046927A1 (en) 1980-12-11 1982-07-15 Josef Dipl.-Chem.Dr.rer.nat. 1000 Berlin Klosa 8-DIALKYLAMINOALKYLAETHER-COFFEIN-PLATINUM COMPLEXES, PROCESS FOR THEIR PRODUCTION AND MEDICINAL PRODUCTS CONTAINING THE SAME
DE3305248C2 (en) * 1983-02-16 1987-04-09 Degussa Ag, 6000 Frankfurt Process for the purification of cis-platinum (II) diammine dichloride
GB8501354D0 (en) * 1985-01-18 1985-02-20 Ici Plc Effecting gas-liquid contact
FI895340A0 (en) * 1988-11-14 1989-11-09 Bristol Myers Squibb Co HYPERTONISK CISPLATIN-LOESNING.
EP0407623A1 (en) * 1989-02-01 1991-01-16 Institut Fizicheskoi Khimii Imeni L.V.Pisarzhevskogo Akademii Nauk Ukrainskoi Ssr Derivatives of platinum (p) with methyl silicone, method of obtaining them and antitumoral means based thereon

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4053587A (en) * 1973-04-13 1977-10-11 Research Corporation Method of treating viral infections

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3112272A1 (en) * 1980-03-31 1982-04-29 Bristol Myers Co PHARMACEUTICAL AGENT
EP0041792A1 (en) * 1980-06-11 1981-12-16 Kureha Kagaku Kogyo Kabushiki Kaisha Platinum compounds having antitumor or antimicrobial activity, and pharmaceutical preparations containing them
US4504487A (en) * 1980-06-11 1985-03-12 Kureha Kagaku Kogyo Kabushiki Kaisha Platinum compound and drug
FR2533439A1 (en) * 1982-09-23 1984-03-30 Erba Farmitalia NOVEL PHARMACEUTICAL COMPOSITIONS BASED ON CIS-PLATINUM-II-DIAMMINO-DICHLORIDE AND PROCESS FOR PREPARING THE SAME
GB2127291A (en) * 1982-09-23 1984-04-11 Erba Farmitalia Compositions containing cisplatinum
EP0143478A1 (en) * 1983-10-24 1985-06-05 Pharmachemie B.V. Stable, aqueous, acidic solution of cis-platinum, suitable for injection
EP0334551A1 (en) * 1988-03-20 1989-09-27 Abic Limited Anti-neoplastic formulations

Also Published As

Publication number Publication date
NZ189556A (en) 1984-05-31
HU177557B (en) 1981-11-28
ES478272A1 (en) 1980-06-16
FR2427097A1 (en) 1979-12-28
SU1192596A3 (en) 1985-11-15
IL56540A (en) 1981-12-31
IE790194L (en) 1979-11-30
DE2906700A1 (en) 1979-12-06
JPS619923B2 (en) 1986-03-27
MY8300152A (en) 1983-12-31
ZA79395B (en) 1980-01-30
DE2906700C2 (en) 1982-06-16
DK39079A (en) 1979-12-01
IE48177B1 (en) 1984-10-17
SE445172B (en) 1986-06-09
CS226002B2 (en) 1984-03-19
PH18056A (en) 1985-03-18
AU4383379A (en) 1979-12-06
ATA164879A (en) 1980-09-15
NL191108C (en) 1995-02-01
DK149192B (en) 1986-03-10
CY1159A (en) 1983-01-28
GB2021946B (en) 1900-01-01
CA1119954A (en) 1982-03-16
KE3230A (en) 1982-10-15
AR218134A1 (en) 1980-05-15
AT362052B (en) 1981-04-27
NO790313L (en) 1979-12-03
NL7901283A (en) 1979-12-04
CH619141A5 (en) 1980-09-15
FI66121B (en) 1984-05-31
FR2427097B1 (en) 1982-11-19
IT7949215A0 (en) 1979-05-29
BE874596A (en) 1979-09-03
PT69207A (en) 1979-03-01
NL191108B (en) 1994-09-01
LU81056A1 (en) 1979-10-30
HK37982A (en) 1982-09-03
IT1116893B (en) 1986-02-10
DD142293A5 (en) 1980-06-18
FI66121C (en) 1984-09-10
SE7900774L (en) 1979-12-01
FI790404A (en) 1979-12-01
NO149914B (en) 1984-04-09
DK149192C (en) 1986-08-04
NO149914C (en) 1984-07-18
AU519873B2 (en) 1981-12-24
JPS54157817A (en) 1979-12-13

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Legal Events

Date Code Title Description
PE20 Patent expired after termination of 20 years

Effective date: 19990130