GB202117016D0 - New pharmaceutical device - Google Patents

New pharmaceutical device

Info

Publication number
GB202117016D0
GB202117016D0 GBGB2117016.2A GB202117016A GB202117016D0 GB 202117016 D0 GB202117016 D0 GB 202117016D0 GB 202117016 A GB202117016 A GB 202117016A GB 202117016 D0 GB202117016 D0 GB 202117016D0
Authority
GB
United Kingdom
Prior art keywords
new pharmaceutical
pharmaceutical device
new
pharmaceutical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB2117016.2A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Orexo AB
Original Assignee
Orexo AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orexo AB filed Critical Orexo AB
Priority to GBGB2117016.2A priority Critical patent/GB202117016D0/en
Publication of GB202117016D0 publication Critical patent/GB202117016D0/en
Priority to CA3238850A priority patent/CA3238850A1/en
Priority to TW111145222A priority patent/TW202333658A/zh
Priority to EP22814495.2A priority patent/EP4236921A1/en
Priority to PCT/GB2022/052996 priority patent/WO2023094826A1/en
Priority to KR1020247019617A priority patent/KR20240111769A/ko
Priority to CN202280078148.XA priority patent/CN118678979A/zh
Priority to IL313016A priority patent/IL313016A/en
Priority to AU2022395916A priority patent/AU2022395916A1/en
Priority to JP2024530530A priority patent/JP2024541470A/ja
Priority to EP22813699.0A priority patent/EP4237051A1/en
Priority to ARP220103244A priority patent/AR127780A1/es
Priority to PCT/GB2022/052983 priority patent/WO2023094816A1/en
Priority to CA3238847A priority patent/CA3238847A1/en
Priority to CN202280077963.4A priority patent/CN118695851A/zh
Priority to MX2024006403A priority patent/MX2024006403A/es
Priority to MX2024006188A priority patent/MX2024006188A/es
Priority to JP2024530531A priority patent/JP2024542520A/ja
Priority to AU2022395920A priority patent/AU2022395920A1/en
Priority to IL313014A priority patent/IL313014A/en
Priority to KR1020247018846A priority patent/KR20240103005A/ko
Priority to US18/323,115 priority patent/US12303472B2/en
Priority to US18/323,101 priority patent/US11957647B2/en
Priority to US18/592,846 priority patent/US12472154B2/en
Priority to ZA2024/03890A priority patent/ZA202403890B/en
Priority to US19/189,960 priority patent/US20250262174A1/en
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/02—Sprayers or atomisers specially adapted for therapeutic purposes operated by air or other gas pressure applied to the liquid or other product to be sprayed or atomised
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/08—Inhaling devices inserted into the nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/0007—Special media to be introduced, removed or treated introduced into the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Biochemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Biophysics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Fire-Extinguishing By Fire Departments, And Fire-Extinguishing Equipment And Control Thereof (AREA)
GBGB2117016.2A 2021-11-25 2021-11-25 New pharmaceutical device Ceased GB202117016D0 (en)

Priority Applications (26)

Application Number Priority Date Filing Date Title
GBGB2117016.2A GB202117016D0 (en) 2021-11-25 2021-11-25 New pharmaceutical device
KR1020247018846A KR20240103005A (ko) 2021-11-25 2022-11-25 아드레날린을 포함하는 약학적 조성물
PCT/GB2022/052983 WO2023094816A1 (en) 2021-11-25 2022-11-25 Pharmaceutical device for use in intranasal administration
CN202280077963.4A CN118695851A (zh) 2021-11-25 2022-11-25 包含肾上腺素的药物组合物
EP22814495.2A EP4236921A1 (en) 2021-11-25 2022-11-25 Pharmaceutical composition comprising adrenaline
PCT/GB2022/052996 WO2023094826A1 (en) 2021-11-25 2022-11-25 Pharmaceutical composition comprising adrenaline
KR1020247019617A KR20240111769A (ko) 2021-11-25 2022-11-25 비강내 투여에 사용되는 새로운 약학적 장치
CN202280078148.XA CN118678979A (zh) 2021-11-25 2022-11-25 用于在鼻内施用中使用的药物装置
IL313016A IL313016A (en) 2021-11-25 2022-11-25 A pharmaceutical preparation that includes adrenaline
AU2022395916A AU2022395916A1 (en) 2021-11-25 2022-11-25 Pharmaceutical device for use in intranasal administration
JP2024530530A JP2024541470A (ja) 2021-11-25 2022-11-25 アドレナリンを含む医薬組成物
EP22813699.0A EP4237051A1 (en) 2021-11-25 2022-11-25 Pharmaceutical device for use in intranasal administration
ARP220103244A AR127780A1 (es) 2021-11-25 2022-11-25 Nueva composición farmacéutica que comprende adrenalina
CA3238850A CA3238850A1 (en) 2021-11-25 2022-11-25 Pharmaceutical composition comprising adrenaline
CA3238847A CA3238847A1 (en) 2021-11-25 2022-11-25 New pharmaceutical device for use in intranasal administration
TW111145222A TW202333658A (zh) 2021-11-25 2022-11-25 包含腎上腺素之新穎醫藥組合物
MX2024006403A MX2024006403A (es) 2021-11-25 2022-11-25 Dispositivo farmaceutico para uso en administracion intranasal.
MX2024006188A MX2024006188A (es) 2021-11-25 2022-11-25 Nueva composicion farmaceutica que comprende adrenalina.
JP2024530531A JP2024542520A (ja) 2021-11-25 2022-11-25 鼻腔内投与における使用のための新しい医薬デバイス
AU2022395920A AU2022395920A1 (en) 2021-11-25 2022-11-25 Pharmaceutical composition comprising adrenaline
IL313014A IL313014A (en) 2021-11-25 2022-11-25 Pharmaceutical device for use in intranasal administration
US18/323,101 US11957647B2 (en) 2021-11-25 2023-05-24 Pharmaceutical composition comprising adrenaline
US18/323,115 US12303472B2 (en) 2021-11-25 2023-05-24 Pharmaceutical device for use in intranasal administration
US18/592,846 US12472154B2 (en) 2021-11-25 2024-03-01 Pharmaceutical composition comprising adrenaline
ZA2024/03890A ZA202403890B (en) 2021-11-25 2024-05-20 Pharmaceutical composition comprising adrenaline
US19/189,960 US20250262174A1 (en) 2021-11-25 2025-04-25 New pharmaceutical device for use in intranasal administration

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB2117016.2A GB202117016D0 (en) 2021-11-25 2021-11-25 New pharmaceutical device

Publications (1)

Publication Number Publication Date
GB202117016D0 true GB202117016D0 (en) 2022-01-12

Family

ID=79602091

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB2117016.2A Ceased GB202117016D0 (en) 2021-11-25 2021-11-25 New pharmaceutical device

Country Status (11)

Country Link
US (2) US12303472B2 (https=)
EP (1) EP4237051A1 (https=)
JP (1) JP2024542520A (https=)
KR (1) KR20240111769A (https=)
CN (2) CN118695851A (https=)
AU (1) AU2022395916A1 (https=)
CA (1) CA3238847A1 (https=)
GB (1) GB202117016D0 (https=)
IL (1) IL313014A (https=)
MX (1) MX2024006403A (https=)
WO (1) WO2023094816A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RS63725B1 (sr) 2020-05-18 2022-12-30 Orexo Ab Nova farmaceutska kompozicija za davanje leka
US12414916B2 (en) 2021-06-10 2025-09-16 Belhaven BioPharma Inc. Dry powder formulations of epinephrine and associated methods
AR127780A1 (es) 2021-11-25 2024-02-28 Orexo Ab Nueva composición farmacéutica que comprende adrenalina
AU2024280073A1 (en) * 2023-05-31 2025-12-11 Orexo Ab Spray-dried compositions comprising adrenergic receptor modulators
US20260108686A1 (en) 2024-10-21 2026-04-23 Belhaven BioPharma Inc. Compositions, devices, and methods for intranasal delivery of dry powder epinephrine

Citations (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5702362A (en) 1995-05-26 1997-12-30 Bayer Aktiengesellschaft Nasal applicator
US6398074B1 (en) 1998-03-10 2002-06-04 Valois S.A. Reservoir, reservoir filling method and device for dispensing fluid contained in the reservoir
US20050001411A1 (en) 2001-09-06 2005-01-06 Christian Theiss Method for the determination of parameters of a seat passenger
US6938798B2 (en) 2000-12-08 2005-09-06 Tebro S.A. Fluid or powdery product dispensing device
US7722566B2 (en) 2003-10-09 2010-05-25 Shin Nippon Biomedical Laboratories, Ltd. Device to deliver a powdery medicine into nasal cavity
WO2010142696A1 (en) 2009-06-11 2010-12-16 Charité - Universitätsmedizin Berlin Use of opioid receptor antagonists for acute treatment of paraphilic arousal states
US20110045088A1 (en) 2009-07-31 2011-02-24 Shin Nippon Biomedical Laboratories, Ltd. Intranasal granisetron and nasal applicator
US7947742B2 (en) 2002-06-28 2011-05-24 Civitas Therapeutics, Inc. Inhalable epinephrine
WO2014004400A2 (en) 2012-06-28 2014-01-03 The Governt. Of The Usa As Represented By The Secretary Of The Department Of Health & Human Services Nasal dry powder delivery system for vaccines and other treatment agents
US9724713B2 (en) 2013-07-05 2017-08-08 Aptar France Sas Fluid or powdery product dispensing device
US20180092839A1 (en) 2016-10-03 2018-04-05 Lance L. Gooberman Medicated spray for treatment of substance abuse, overdose, addiction and impulse control disorders
WO2019038756A1 (en) 2017-08-20 2019-02-28 Solubest Ltd. DRY POWDER COMPOSITIONS FOR INTRANASAL DELIVERY
US10653690B1 (en) 2019-07-09 2020-05-19 Orexo Ab Pharmaceutical composition for nasal delivery

Family Cites Families (110)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE759520A (fr) 1969-11-28 1971-04-30 Aspro Nicholas Ltd Compositions d'aspirine
US5082669A (en) 1989-07-20 1992-01-21 Dainippon Pharmaceutical Co., Ltd. Rapid-releasing oral particle pharmaceutical preparation with unpleasant taste masked
SE8904296D0 (sv) 1989-12-21 1989-12-21 Pharmacia Ab Transdermal system
EP0657176B1 (en) 1993-12-06 2000-09-20 Takeda Chemical Industries, Ltd. Composition containing a water-insoluble or slightly water-soluble compound with enhanced water-solubility
CH689139A5 (de) 1995-04-03 1998-10-30 Cerbios Pharma Sa Verfahren zur Herstellung einer liposomalen, in Wasser dispergierbaren, oral zu verabreichenden, festen, trockenen therapeutischen Formulierung.
KR100606857B1 (ko) 1998-07-08 2006-08-01 키린-암젠 인코포레이티드 고분자 의약품 함유 분말상 경점막 투여 제제
JP2000178184A (ja) 1998-12-17 2000-06-27 Lion Corp 粒状組成物、錠剤及び粒状組成物の製造方法
GB9908921D0 (en) 1999-04-19 1999-06-16 Britannia Pharmaceuticals Ltd Spray dispenser for opiod antagonists
US6264981B1 (en) 1999-10-27 2001-07-24 Anesta Corporation Oral transmucosal drug dosage using solid solution
GB0003782D0 (en) 2000-02-17 2000-04-05 Dumex Ltd As Process
US6316029B1 (en) 2000-05-18 2001-11-13 Flak Pharma International, Ltd. Rapidly disintegrating solid oral dosage form
KR20010107754A (ko) 2000-05-26 2001-12-07 민경윤 경구투여용 속용정의 제조 방법
IN192750B (https=) 2000-12-15 2004-05-15 Ranbaxy Lab Ltd
US6443152B1 (en) * 2001-01-12 2002-09-03 Becton Dickinson And Company Medicament respiratory delivery device
ITMI20012174A1 (it) 2001-10-18 2003-04-18 Univ Parma Polvere per somministrazione nasale di farmaci
FR2834212B1 (fr) 2001-12-27 2004-07-09 Besins Int Belgique Utilisation d'une poudre a liberation immediate dans des compositions pharmaceutiques et nutraceutiques
GB0201367D0 (en) 2002-01-22 2002-03-13 Ml Lab Plc Composition
AU2006207868A1 (en) * 2002-03-20 2006-09-28 Alkermes, Inc. Method and apparatus for producing dry particles
WO2004054511A2 (en) 2002-12-13 2004-07-01 The Regents Of The University Of California Analgesic combination comprising nalbuphine
CN1777411B (zh) 2003-02-24 2013-01-02 药品生产公司 经粘膜药物递送系统
WO2004100857A2 (en) 2003-05-07 2004-11-25 Akina, Inc. Highly plastic granules for making fast melting tablets
US20060115529A1 (en) 2003-05-07 2006-06-01 Seonghoon Jeong Fast-melting tablets having taste-masking and sustained release properties
CA2528064C (en) 2003-06-13 2010-01-12 Advanced Inhalation Research, Inc. Low dose pharmaceutical powders for inhalation
CN100471497C (zh) 2003-06-25 2009-03-25 中国人民解放军军事医学科学院毒物药物研究所 盐酸纳洛酮鼻粉剂
US20050042178A1 (en) 2003-08-18 2005-02-24 Boehringer Ingelheim International Gmbh Microparticles containing the CGRP-antagonist 1-[N2-[3,5-dibrom-N-[[4-(3,4-dihydro-2(1H)-oxoquinazoline-3-yl)-1-piperidinyl]carbonyl]-D-tyrosyl]-L-lysyl]-4-(4-pyridinyl)-piperazine, process for preparing and the use thereof as inhalation powder
WO2005044186A2 (en) 2003-10-28 2005-05-19 Glaxo Group Limited Inhalable pharmaceutical formulations employing desiccating agents and methods of administering the same
CN1640402A (zh) 2004-01-02 2005-07-20 广东奇方药业有限公司 一种稳定的纳洛酮粉针剂
IL159729A0 (en) 2004-01-06 2004-06-20 Doron I Friedman Non-aqueous composition for oral delivery of insoluble bioactive agents
US8642079B2 (en) 2004-02-23 2014-02-04 Hormos Medical Corporation Solid formulations of ospemifene
US9895444B2 (en) 2004-08-25 2018-02-20 Aegis Therapeutics, Llc Compositions for drug administration
CN1615867A (zh) 2004-10-22 2005-05-18 北京阳光润禾科技有限公司 注射用盐酸纳洛酮冻干粉针制剂
CN1781479B (zh) 2004-12-02 2010-06-30 和记黄埔医药企业有限公司 一种马蔺子素分散体系及其制备方法
CN101132769A (zh) 2005-02-10 2008-02-27 奥瑞克索股份公司 用于药物的跨黏膜给药的药物组合物
KR101233235B1 (ko) 2005-08-26 2013-02-15 에스케이케미칼주식회사 초기 용출율이 개선된 프란루카스트 고체분산체의 약제학적조성물 및 그의 제조방법
US20070202163A1 (en) 2005-09-09 2007-08-30 Mutasem Rawas-Qalaji Fast-disintegrating epinephrine tablets for buccal or sublingual administration
CN1939358A (zh) 2005-09-30 2007-04-04 江西本草天工科技有限责任公司 肿节风分散片
CN1813739A (zh) 2005-11-25 2006-08-09 王颖 一种注射用盐酸纳美芬冻干粉针制剂
JP2009524646A (ja) 2006-01-27 2009-07-02 ザ・プロヴォスト，フェローズ・アンド・スカラーズ・オブ・ザ・カレッジ・オブ・ザ・ホーリー・アンド・アンディヴァイデッド・トリニティー・オブ・クイーン・エリザベス，ニア・ダブリン 多孔性微粒子の製造方法
WO2007096906A2 (en) 2006-02-27 2007-08-30 Panacea Biotec Ltd. Novel buccoadhesive compositions and process of preparation thereof
US20100226979A1 (en) 2006-03-21 2010-09-09 Jubilant Organosys Limited Taste Masked Phamaceutical Composition for Oral Solid Dosage form and Process for Preparing the Same Using Magnesium Aluminium Silicate
US20090208576A1 (en) 2006-03-31 2009-08-20 Gandhi Anilkumar S Orally Disintegrating Tablets
EP2061427B1 (en) 2006-09-15 2011-07-20 Echo Pharmaceuticals B.V. Granulate containing a pharmaceutically active substance and an emulsifier and method for its manufacture
US20080269347A1 (en) 2006-09-28 2008-10-30 Azopharma, Inc. Epinephrine formulations
CA2678455C (en) 2007-01-10 2019-02-12 Board Of Regents The University Of Texas System Enhanced delivery of immunosuppressive drug compositions for pulmonary delivery
WO2009040595A1 (en) 2007-09-28 2009-04-02 Wockhardt Research Centre Multi-dose pharmaceutical composition of analgesic for nasal administration
CA2718255C (en) 2008-03-11 2016-08-23 Aska Pharmaceutical Co., Ltd. Solid dispersion and pharmaceutical composition of the same, and production processes thereof
US20090246256A1 (en) 2008-03-27 2009-10-01 Al-Ghananeem Abeer M Compositions and Methods for Transmucosal Delivery of Lofexidine
US20090264530A1 (en) 2008-04-16 2009-10-22 Nickell Robert P Combined nsaid and acetaminophen formulation and method
US8715715B2 (en) 2008-11-03 2014-05-06 Nal Pharmaceuticals Ltd. Dosage form for insertion into the mouth
DK2432502T3 (en) 2009-05-20 2018-03-12 Aeras STABLE, SPRAY DRIED, IMMUNOGENE, VIRUS COMPOSITIONS
MX337126B (es) 2009-05-29 2016-02-12 Pearl Therapeutics Inc Administracion respiratoria de agentes activos.
US20110097401A1 (en) 2009-06-12 2011-04-28 Meritage Pharma, Inc. Methods for treating gastrointestinal disorders
CA2775404C (en) 2009-09-25 2017-01-03 Dr. Reddy's Laboratories Limited Formulations comprising triptan compounds
CA2809263A1 (en) 2010-08-27 2012-03-01 Eleni Dokou Pharmaceutical composition and administrations thereof
AU2011296343B2 (en) 2010-08-30 2015-12-10 Pulmatrix Operating Company, Inc. Dry powder formulations and methods for treating pulmonary diseases
MY165826A (en) 2010-10-01 2018-05-17 Cipla Ltd Pharmaceutical composition
CA2819663C (en) 2010-12-02 2019-12-24 Adare Pharmaceuticals, Inc. Rapidly dispersing granules, orally disintegrating tablets and methods
MX359670B (es) 2011-02-18 2018-10-05 Biolingus Ip Llc Proceso para preparar productos que comprenden activos estabilizados y composiciones que los comprenden.
MY194947A (en) 2011-05-13 2022-12-27 Euro Celtique Sa Intranasal pharmaceutical dosage forms comprising naloxone
JP6054380B2 (ja) 2012-05-11 2016-12-27 株式会社アクティバスファーマ 有機化合物ナノ粉体、その製造方法ならびに懸濁液
CA3169368A1 (en) 2012-06-15 2014-01-09 Nova Southeastern University Epinephrine nanoparticles, methods of fabrication thereof, and methods for use thereof for treatment of conditions responsive to epinephrine
US9789071B2 (en) * 2012-06-27 2017-10-17 G2B Pharma, Inc. Intranasal formulation of epinephrine for the treatment of anaphylaxis
AU2014315459A1 (en) 2013-09-03 2016-04-07 G2B Pharma Inc. Intranasal formulation for the treatment of cardiopulmonary resuscitation (CPR), cardiac life support (CLS), anaphylaxis and/or anaphylactoid reactions
EP2886107A1 (en) 2013-12-17 2015-06-24 ObsEva S.A. Oral formulations of pyrrolydine derivatives
WO2015095389A1 (en) 2013-12-18 2015-06-25 Aegis Therapeutics, Llc Compositions for drug administration
US9192570B2 (en) 2013-12-20 2015-11-24 AntiOP, Inc. Intranasal naloxone compositions and methods of making and using same
US9480644B2 (en) 2014-03-14 2016-11-01 Opiant Pharmaceuticals, Inc. Nasal drug products and methods of their use
US10085937B2 (en) 2014-03-14 2018-10-02 Adapt Pharma Limited Nasal drug products and methods of their use
DK3125875T3 (da) 2014-04-04 2023-07-24 Ai Therapeutics Inc Inhalerbar rapamycinformulering til behandling af aldersrelaterede tilstande
US20190008759A1 (en) 2014-07-03 2019-01-10 Darren Rubin Safer and more effective methods of transmucosal delivery for raising blood pressure and stimulating the body
US11135155B2 (en) 2014-07-08 2021-10-05 Hikma Pharmaceuticals Usa Inc. Liquid naloxone spray
EP3174534A1 (en) 2014-08-01 2017-06-07 KRKA, d.d., Novo mesto Pharmaceutical formulation comprising an opioid agonist and an opioid antagonist prepared by melt granulation using lipid esters
CA2961829C (en) * 2014-09-18 2023-09-12 Virun, Inc. Pre-spray emulsions and powders containing non-polar compounds
JP6919093B2 (ja) 2014-10-08 2021-08-18 ザンボン ソシエタ ペル アチオニ 配合物の安定性を高めるために噴霧乾燥によって得られる少なくとも１種の乾燥粉末を含む組成物
ES2949137T3 (es) 2014-11-14 2023-09-25 Asoltech Srl Composición a base de coq10 campo de la invención
EP3025705B8 (en) 2014-11-25 2018-11-28 Sanofi Ilaç Sanayi ve Ticaret Anonim Sirketi Stable ivabradine formulations
CN104547220A (zh) 2014-12-30 2015-04-29 陈宏� 一种治疗儿童视觉疲劳的中药组合物及其制剂
US10166197B2 (en) 2015-02-13 2019-01-01 St. John's University Sugar ester nanoparticle stabilizers
EA034820B1 (ru) 2015-02-17 2020-03-25 Эли Лилли Энд Компани Порошковый состав для интраназального введения для лечения гипогликемии
US20170189352A1 (en) 2015-03-13 2017-07-06 Par Pharmaceutical, Inc. Epinephrine formulations
EP3280740A4 (en) 2015-04-08 2019-03-27 Ling, Chang-Chun PHARMACEUTICAL COMPOSITIONS OF POLYANIONIC AND NONIONIC CYCLODEXTRIN BASED DENDRIMERS AND USES THEREOF
KR20180002750A (ko) 2015-05-01 2018-01-08 키비타스 테라퓨틱스, 인코포레이티드. 폐 전달용 졸미트립탄 분말
US10039710B2 (en) 2015-09-18 2018-08-07 Insys Development Company, Inc. Epinephrine spray formulations
JP6953414B2 (ja) 2016-01-20 2021-10-27 フラリー パウダーズ エルエルシーＦｌｕｒｒｙ Ｐｏｗｄｅｒｓ，Ｌｌｃ 親油性成分を含む吸入に好適な分散性の噴霧乾燥粉末を製造する方法
ITUB20161027A1 (it) 2016-02-24 2017-08-24 Altergon Sa Preparazioni farmaceutiche oromucosali ad elevata biodisponibilita’ a base di ciclodestrina e sucralosio
US20190364946A1 (en) 2016-03-16 2019-12-05 Omegatri As Powders and tablets comprising omega-3 fatty acid derivatives and methods for their production
US20170312226A1 (en) 2016-04-28 2017-11-02 Ascent Pharmaceuticals, Inc. Pharmaceutical dosage forms
EP3463375A1 (en) 2016-06-03 2019-04-10 M Et P Pharma AG Nasal pharmaceutical compositions with a porous excipient
US20190350881A1 (en) 2016-06-17 2019-11-21 Ys Pharmtech Stabilization of epinephrine formulations
RU2747237C2 (ru) * 2016-07-06 2021-04-29 Маккормик Энд Компани, Инкорпорейтед Природные инкапсулированные ароматизирующие продукты
WO2018025089A2 (en) 2016-08-05 2018-02-08 Shin Nippon Biomedical Laboratories, Ltd. Pharmaceutical compositions
US20190231707A1 (en) 2016-09-28 2019-08-01 Chrono Therapeutics Inc. Transdermal drug delivery device for delivering opioids
WO2018064672A1 (en) 2016-09-30 2018-04-05 Opiant Pharmaceuticals, Inc. Treatment with intranasal naloxone
WO2018089709A1 (en) 2016-11-09 2018-05-17 Opiant Pharmaceuticals, Inc. Compositions, devices, and methods for the treatment of opioid-receptor-mediated conditions
CN110139651A (zh) 2016-11-18 2019-08-16 欧邦特制药公司 用于治疗阿片样物质过量的组合物和方法
WO2018148382A1 (en) 2017-02-10 2018-08-16 Mucodel Pharma Llc Chemically stable compositions of a pharmaceutical active agent in a multi-chambered delivery system for mucosal delivery
WO2018195029A1 (en) 2017-04-17 2018-10-25 Insys Development Company, Inc. Epinephrine spray formulations
US20180193332A1 (en) 2017-10-09 2018-07-12 Adapt Pharma Operations Limited Low-temperature stable opioid antagonist solutions
WO2019139865A1 (en) 2018-01-10 2019-07-18 Insys Development Company. Inc. Methods of stabilizing epinephrine
WO2019157099A1 (en) 2018-02-06 2019-08-15 Aegis Therapeutics, Llc Intranasal epinephrine formulations and methods for the treatment of disease
WO2019182745A1 (en) 2018-03-19 2019-09-26 Bryn Pharma, LLC Epinephrine spray formulations
CN112512506A (zh) 2018-06-13 2021-03-16 希克玛药物美国股份有限公司 肾上腺素喷雾制剂
WO2020205663A1 (en) 2019-03-29 2020-10-08 The Regents Of The University Of California Inhaled statins as bronchodilators to improve lung function in respiratory diseases
US10729687B1 (en) 2019-07-09 2020-08-04 Orexo Ab Pharmaceutical composition for nasal delivery
FR3098420B1 (fr) 2019-07-10 2021-07-09 Aptar France Sas Dispositif de distribution nasale de poudre
US11400045B2 (en) 2020-03-16 2022-08-02 Nasus Pharma Ltd. Treatment with powdered intranasal epinephrine
RS63725B1 (sr) 2020-05-18 2022-12-30 Orexo Ab Nova farmaceutska kompozicija za davanje leka
FR3121047B1 (fr) 2021-03-29 2023-07-14 Aptar France Sas Dispositif de distribution nasale de poudre
US11617716B2 (en) 2021-06-10 2023-04-04 Belhaven BioPharma Inc. Dry powder formulations of epinephrine and associated methods
AR127780A1 (es) 2021-11-25 2024-02-28 Orexo Ab Nueva composición farmacéutica que comprende adrenalina

Patent Citations (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5702362A (en) 1995-05-26 1997-12-30 Bayer Aktiengesellschaft Nasal applicator
US6398074B1 (en) 1998-03-10 2002-06-04 Valois S.A. Reservoir, reservoir filling method and device for dispensing fluid contained in the reservoir
US6938798B2 (en) 2000-12-08 2005-09-06 Tebro S.A. Fluid or powdery product dispensing device
US20050001411A1 (en) 2001-09-06 2005-01-06 Christian Theiss Method for the determination of parameters of a seat passenger
US8747813B2 (en) 2002-06-28 2014-06-10 Civitas Therapeutics, Inc. Inhalable epinephrine
US7947742B2 (en) 2002-06-28 2011-05-24 Civitas Therapeutics, Inc. Inhalable epinephrine
US8415397B2 (en) 2002-06-28 2013-04-09 Civitas Therapeutics, Inc. Inhalable epinephrine
US7722566B2 (en) 2003-10-09 2010-05-25 Shin Nippon Biomedical Laboratories, Ltd. Device to deliver a powdery medicine into nasal cavity
WO2010142696A1 (en) 2009-06-11 2010-12-16 Charité - Universitätsmedizin Berlin Use of opioid receptor antagonists for acute treatment of paraphilic arousal states
US20110045088A1 (en) 2009-07-31 2011-02-24 Shin Nippon Biomedical Laboratories, Ltd. Intranasal granisetron and nasal applicator
WO2014004400A2 (en) 2012-06-28 2014-01-03 The Governt. Of The Usa As Represented By The Secretary Of The Department Of Health & Human Services Nasal dry powder delivery system for vaccines and other treatment agents
US9724713B2 (en) 2013-07-05 2017-08-08 Aptar France Sas Fluid or powdery product dispensing device
US20180092839A1 (en) 2016-10-03 2018-04-05 Lance L. Gooberman Medicated spray for treatment of substance abuse, overdose, addiction and impulse control disorders
WO2019038756A1 (en) 2017-08-20 2019-02-28 Solubest Ltd. DRY POWDER COMPOSITIONS FOR INTRANASAL DELIVERY
US10653690B1 (en) 2019-07-09 2020-05-19 Orexo Ab Pharmaceutical composition for nasal delivery

Non-Patent Citations (11)

* Cited by examiner, † Cited by third party
Title
"Aulton's Pharmaceutics: The Design and Manufacture of Medicines", 2017, ELSEVIER
"Remington: The Science and Practice of Pharmacy", 2020, PHARMACEUTICAL PRESS
"The HLB System: A Time-Saving Guide to Emulsifier Selection", 1976, ICI AMERICAS INC, pages: 20 - 21
BERTAN ET AL., EUR. J. PHARM. SCI., vol. 27, 2006, pages 62
GANDHI, ADVANCED DRUG DELIVERY REVIEWS, vol. 43, 1994, pages 67
J. DRUG DELIVERY, 2018, pages 1 - 19
KOUZHOU ET AL.: "Amorphous Solid Dispersions", 2014, SPRINGER
LACHMAN ET AL.: "The Theory and Practice of Industrial Pharmacy", 2015, CBS
RUSSO ET AL., J. PHARM. SCI., vol. 95, 2006, pages 2253
SHOJAEI, J. PHARM. PHARMACEUTICAL SCI., vol. 15, 1998, pages 19
VENGEROVICH ET AL., BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE, vol. 163, 2017, pages 737

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