GB202003668D0 - GPR52 Modulator compounds - Google Patents
GPR52 Modulator compoundsInfo
- Publication number
- GB202003668D0 GB202003668D0 GBGB2003668.7A GB202003668A GB202003668D0 GB 202003668 D0 GB202003668 D0 GB 202003668D0 GB 202003668 A GB202003668 A GB 202003668A GB 202003668 D0 GB202003668 D0 GB 202003668D0
- Authority
- GB
- United Kingdom
- Prior art keywords
- gpr52
- modulator compounds
- modulator
- compounds
- gpr52 modulator
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/16—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Amplifiers (AREA)
- Optical Modulation, Optical Deflection, Nonlinear Optics, Optical Demodulation, Optical Logic Elements (AREA)
Priority Applications (23)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB2003668.7A GB202003668D0 (en) | 2020-03-13 | 2020-03-13 | GPR52 Modulator compounds |
| PT217131036T PT4117784T (pt) | 2020-03-13 | 2021-03-15 | Compostos moduladores de gpr52 |
| EP21713103.6A EP4117784B1 (en) | 2020-03-13 | 2021-03-15 | Gpr52 modulator compounds |
| KR1020227035100A KR20220152296A (ko) | 2020-03-13 | 2021-03-15 | Gpr52 조절제 화합물 |
| AU2021235257A AU2021235257A1 (en) | 2020-03-13 | 2021-03-15 | GPR52 modulator compounds |
| LTEPPCT/GB2021/050638T LT4117784T (lt) | 2020-03-13 | 2021-03-15 | Gpr52 moduliuojantys junginiai |
| JP2022555137A JP7492597B2 (ja) | 2020-03-13 | 2021-03-15 | Ｇｐｒ５２モジュレーター化合物 |
| PCT/GB2021/050638 WO2021181122A1 (en) | 2020-03-13 | 2021-03-15 | Gpr52 modulator compounds |
| DK21713103.6T DK4117784T3 (da) | 2020-03-13 | 2021-03-15 | Gpr52-modulatorforbindelser |
| IL296413A IL296413B2 (en) | 2020-03-13 | 2021-03-15 | GPR52 modulator compounds |
| PL21713103.6T PL4117784T3 (pl) | 2020-03-13 | 2021-03-15 | Związki stanowiące modulator gpr52 |
| ES21713103T ES2992600T3 (en) | 2020-03-13 | 2021-03-15 | Gpr52 modulator compounds |
| CA3175429A CA3175429A1 (en) | 2020-03-13 | 2021-03-15 | Gpr52 modulator compounds |
| SM20240402T SMT202400402T1 (it) | 2020-03-13 | 2021-03-15 | Composti modulatori gpr52 |
| BR112022018287A BR112022018287A2 (pt) | 2020-03-13 | 2021-03-15 | Compostos moduladores de gpr52 |
| MX2022011333A MX2022011333A (es) | 2020-03-13 | 2021-03-15 | Compuestos moduladores de gpr52. |
| CN202180033813.9A CN115515681B (zh) | 2020-03-13 | 2021-03-15 | Gpr52调节剂化合物 |
| SI202130212T SI4117784T1 (sl) | 2020-03-13 | 2021-03-15 | Gpr52 modulatorne spojine |
| RS20241089A RS66063B1 (sr) | 2020-03-13 | 2021-03-15 | Jedinjenja gpr52 modulatora |
| HRP20241375TT HRP20241375T1 (hr) | 2020-03-13 | 2021-03-15 | Spojevi modulatora gpr52 |
| FIEP21713103.6T FI4117784T3 (fi) | 2020-03-13 | 2021-03-15 | GPR52:n modulaattoriyhdisteitä |
| HUE21713103A HUE068758T2 (hu) | 2020-03-13 | 2021-03-15 | GPR52 modulátorvegyületek |
| US17/909,792 US20240254101A1 (en) | 2020-03-13 | 2021-03-15 | Gpr52 modulator compounds |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB2003668.7A GB202003668D0 (en) | 2020-03-13 | 2020-03-13 | GPR52 Modulator compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB202003668D0 true GB202003668D0 (en) | 2020-04-29 |
Family
ID=70453676
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GBGB2003668.7A Ceased GB202003668D0 (en) | 2020-03-13 | 2020-03-13 | GPR52 Modulator compounds |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US20240254101A1 (https=) |
| EP (1) | EP4117784B1 (https=) |
| JP (1) | JP7492597B2 (https=) |
| KR (1) | KR20220152296A (https=) |
| CN (1) | CN115515681B (https=) |
| AU (1) | AU2021235257A1 (https=) |
| BR (1) | BR112022018287A2 (https=) |
| CA (1) | CA3175429A1 (https=) |
| DK (1) | DK4117784T3 (https=) |
| ES (1) | ES2992600T3 (https=) |
| FI (1) | FI4117784T3 (https=) |
| GB (1) | GB202003668D0 (https=) |
| HR (1) | HRP20241375T1 (https=) |
| HU (1) | HUE068758T2 (https=) |
| IL (1) | IL296413B2 (https=) |
| LT (1) | LT4117784T (https=) |
| MX (1) | MX2022011333A (https=) |
| PL (1) | PL4117784T3 (https=) |
| PT (1) | PT4117784T (https=) |
| RS (1) | RS66063B1 (https=) |
| SI (1) | SI4117784T1 (https=) |
| SM (1) | SMT202400402T1 (https=) |
| WO (1) | WO2021181122A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW202206413A (zh) | 2020-04-22 | 2022-02-16 | 美商紐羅克里生物科學有限公司 | Gpr52調節劑及其使用方法 |
| EP4330232A1 (en) * | 2021-04-26 | 2024-03-06 | Neurocrine Biosciences, Inc. | Gpr52 modulators and methods of use |
| GB202113186D0 (en) | 2021-09-15 | 2021-10-27 | Heptares Therapeutics Ltd | GPR52 Modulator compounds |
| WO2024091541A1 (en) * | 2022-10-26 | 2024-05-02 | Neurocrine Biosciences, Inc. | Compounds and compositions as gpr52 modulators |
| JP2026508053A (ja) * | 2022-10-26 | 2026-03-10 | ニューロクライン バイオサイエンシーズ，インコーポレイテッド | Ｇｐｒ５２モジュレーターとしての化合物および組成物 |
| WO2024091542A1 (en) * | 2022-10-26 | 2024-05-02 | Neurocrine Biosciences, Inc. | Compounds and compositions as gpr52 modulators |
| WO2025252061A1 (zh) * | 2024-06-04 | 2025-12-11 | 海思科医药集团股份有限公司 | 一种gpr52激动剂及其在医药上的应用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005037797A1 (en) * | 2003-10-21 | 2005-04-28 | Pharmacia Corporation | Substituted pyrazole urea compounds for the treatment of inflammation |
| WO2009107391A1 (ja) | 2008-02-27 | 2009-09-03 | 武田薬品工業株式会社 | ６員芳香環含有化合物 |
| WO2011078360A1 (ja) | 2009-12-24 | 2011-06-30 | 武田薬品工業株式会社 | アミド化合物 |
| EP2530078A1 (en) | 2010-01-27 | 2012-12-05 | Takeda Pharmaceutical Company Limited | Thiazole derivative |
| KR20180004193A (ko) * | 2015-04-29 | 2018-01-10 | 아레나 파마슈티칼스, 인크. | Gpr52와 관련된 장애의 치료 또는 예방을 위한 gpr52 조절제로서 1-헤테로아릴-인돌린-4-카르복스아미드 |
| JP7394747B2 (ja) * | 2017-09-13 | 2023-12-08 | ノバルティス アーゲー | ジフェニル誘導体及びその使用 |
-
2020
- 2020-03-13 GB GBGB2003668.7A patent/GB202003668D0/en not_active Ceased
-
2021
- 2021-03-15 HR HRP20241375TT patent/HRP20241375T1/hr unknown
- 2021-03-15 ES ES21713103T patent/ES2992600T3/es active Active
- 2021-03-15 EP EP21713103.6A patent/EP4117784B1/en active Active
- 2021-03-15 SI SI202130212T patent/SI4117784T1/sl unknown
- 2021-03-15 US US17/909,792 patent/US20240254101A1/en active Pending
- 2021-03-15 RS RS20241089A patent/RS66063B1/sr unknown
- 2021-03-15 AU AU2021235257A patent/AU2021235257A1/en active Pending
- 2021-03-15 IL IL296413A patent/IL296413B2/en unknown
- 2021-03-15 WO PCT/GB2021/050638 patent/WO2021181122A1/en not_active Ceased
- 2021-03-15 LT LTEPPCT/GB2021/050638T patent/LT4117784T/lt unknown
- 2021-03-15 DK DK21713103.6T patent/DK4117784T3/da active
- 2021-03-15 PT PT217131036T patent/PT4117784T/pt unknown
- 2021-03-15 CA CA3175429A patent/CA3175429A1/en active Pending
- 2021-03-15 SM SM20240402T patent/SMT202400402T1/it unknown
- 2021-03-15 MX MX2022011333A patent/MX2022011333A/es unknown
- 2021-03-15 PL PL21713103.6T patent/PL4117784T3/pl unknown
- 2021-03-15 KR KR1020227035100A patent/KR20220152296A/ko active Pending
- 2021-03-15 HU HUE21713103A patent/HUE068758T2/hu unknown
- 2021-03-15 BR BR112022018287A patent/BR112022018287A2/pt unknown
- 2021-03-15 FI FIEP21713103.6T patent/FI4117784T3/fi active
- 2021-03-15 CN CN202180033813.9A patent/CN115515681B/zh active Active
- 2021-03-15 JP JP2022555137A patent/JP7492597B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP7492597B2 (ja) | 2024-05-29 |
| EP4117784A1 (en) | 2023-01-18 |
| SMT202400402T1 (it) | 2024-11-15 |
| IL296413A (en) | 2022-11-01 |
| ES2992600T3 (en) | 2024-12-16 |
| CA3175429A1 (en) | 2021-09-16 |
| AU2021235257A1 (en) | 2022-10-06 |
| SI4117784T1 (sl) | 2025-03-31 |
| LT4117784T (lt) | 2024-10-25 |
| EP4117784B1 (en) | 2024-08-28 |
| DK4117784T3 (da) | 2024-10-14 |
| CN115515681A (zh) | 2022-12-23 |
| CN115515681B (zh) | 2024-09-03 |
| JP2023519666A (ja) | 2023-05-12 |
| RS66063B1 (sr) | 2024-11-29 |
| IL296413B1 (en) | 2025-11-01 |
| FI4117784T3 (fi) | 2024-10-10 |
| US20240254101A1 (en) | 2024-08-01 |
| KR20220152296A (ko) | 2022-11-15 |
| MX2022011333A (es) | 2022-12-08 |
| HUE068758T2 (hu) | 2025-01-28 |
| HRP20241375T1 (hr) | 2024-12-20 |
| PL4117784T3 (pl) | 2025-01-13 |
| BR112022018287A2 (pt) | 2022-11-22 |
| WO2021181122A1 (en) | 2021-09-16 |
| PT4117784T (pt) | 2024-10-07 |
| IL296413B2 (en) | 2026-03-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AT | Applications terminated before publication under section 16(1) |