GB201816369D0 - Pharmaceutical compounds - Google Patents

Pharmaceutical compounds

Info

Publication number
GB201816369D0
GB201816369D0 GBGB1816369.1A GB201816369A GB201816369D0 GB 201816369 D0 GB201816369 D0 GB 201816369D0 GB 201816369 A GB201816369 A GB 201816369A GB 201816369 D0 GB201816369 D0 GB 201816369D0
Authority
GB
United Kingdom
Prior art keywords
pharmaceutical compounds
pharmaceutical
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB1816369.1A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sareum Ltd
Original Assignee
Sareum Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sareum Ltd filed Critical Sareum Ltd
Priority to GBGB1816369.1A priority Critical patent/GB201816369D0/en
Publication of GB201816369D0 publication Critical patent/GB201816369D0/en
Priority to IL281599A priority patent/IL281599B2/en
Priority to KR1020217013504A priority patent/KR102844196B1/ko
Priority to DK19794095.0T priority patent/DK3864009T3/da
Priority to US17/283,151 priority patent/US12187716B2/en
Priority to PT197940950T priority patent/PT3864009T/pt
Priority to MX2021003929A priority patent/MX2021003929A/es
Priority to ES19794095T priority patent/ES3021420T3/es
Priority to JP2021543577A priority patent/JP7383030B2/ja
Priority to SG11202102490TA priority patent/SG11202102490TA/en
Priority to EP19794095.0A priority patent/EP3864009B1/en
Priority to CA3111049A priority patent/CA3111049A1/en
Priority to BR112021006424A priority patent/BR112021006424A2/pt
Priority to PL19794095.0T priority patent/PL3864009T3/pl
Priority to PCT/EP2019/077118 priority patent/WO2020074461A1/en
Priority to FIEP19794095.0T priority patent/FI3864009T3/fi
Priority to CN201980066166.4A priority patent/CN113056456B/zh
Priority to AU2019359320A priority patent/AU2019359320B2/en
Ceased legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/541Non-condensed thiazines containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/34Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/48Nitrogen atoms not forming part of a nitro radical

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
GBGB1816369.1A 2018-10-08 2018-10-08 Pharmaceutical compounds Ceased GB201816369D0 (en)

Priority Applications (18)

Application Number Priority Date Filing Date Title
GBGB1816369.1A GB201816369D0 (en) 2018-10-08 2018-10-08 Pharmaceutical compounds
AU2019359320A AU2019359320B2 (en) 2018-10-08 2019-10-07 TYK2 kinase inhibitors
JP2021543577A JP7383030B2 (ja) 2018-10-08 2019-10-07 Tyk2キナーゼ阻害剤
EP19794095.0A EP3864009B1 (en) 2018-10-08 2019-10-07 Tyk2 kinase inhibitors
DK19794095.0T DK3864009T3 (da) 2018-10-08 2019-10-07 Tyk2-kinasehæmmere
US17/283,151 US12187716B2 (en) 2018-10-08 2019-10-07 TYK2 kinase inhibitors
PT197940950T PT3864009T (pt) 2018-10-08 2019-10-07 Inibidores da tyk2 quinase
MX2021003929A MX2021003929A (es) 2018-10-08 2019-10-07 Compuestos farmaceuticos.
ES19794095T ES3021420T3 (en) 2018-10-08 2019-10-07 Tyk2 kinase inhibitors
IL281599A IL281599B2 (en) 2018-10-08 2019-10-07 2-(2,6-dichlorophenyl)-5-[4-(1,1-dioxo-1,4-thiazinane-4-carbonyl)anilino]-1,3-oxazole-4- carboxamide, and its 3-fluoro derivative
SG11202102490TA SG11202102490TA (en) 2018-10-08 2019-10-07 Tyk2 kinase inhibitors
KR1020217013504A KR102844196B1 (ko) 2018-10-08 2019-10-07 Tyk2 키나제 억제제
CA3111049A CA3111049A1 (en) 2018-10-08 2019-10-07 Tyk2 kinase inhibitors
BR112021006424A BR112021006424A2 (pt) 2018-10-08 2019-10-07 inibidores de quinase tyk2
PL19794095.0T PL3864009T3 (pl) 2018-10-08 2019-10-07 Inhibitory kinazy tyk2
PCT/EP2019/077118 WO2020074461A1 (en) 2018-10-08 2019-10-07 Tyk2 kinase inhibitors
FIEP19794095.0T FI3864009T3 (fi) 2018-10-08 2019-10-07 TYK2-kinaasi-inhibiittoreita
CN201980066166.4A CN113056456B (zh) 2018-10-08 2019-10-07 Tyk2激酶抑制剂

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1816369.1A GB201816369D0 (en) 2018-10-08 2018-10-08 Pharmaceutical compounds

Publications (1)

Publication Number Publication Date
GB201816369D0 true GB201816369D0 (en) 2018-11-28

Family

ID=64397425

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB1816369.1A Ceased GB201816369D0 (en) 2018-10-08 2018-10-08 Pharmaceutical compounds

Country Status (18)

Country Link
US (1) US12187716B2 (enExample)
EP (1) EP3864009B1 (enExample)
JP (1) JP7383030B2 (enExample)
KR (1) KR102844196B1 (enExample)
CN (1) CN113056456B (enExample)
AU (1) AU2019359320B2 (enExample)
BR (1) BR112021006424A2 (enExample)
CA (1) CA3111049A1 (enExample)
DK (1) DK3864009T3 (enExample)
ES (1) ES3021420T3 (enExample)
FI (1) FI3864009T3 (enExample)
GB (1) GB201816369D0 (enExample)
IL (1) IL281599B2 (enExample)
MX (1) MX2021003929A (enExample)
PL (1) PL3864009T3 (enExample)
PT (1) PT3864009T (enExample)
SG (1) SG11202102490TA (enExample)
WO (1) WO2020074461A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB202005114D0 (en) * 2020-04-07 2020-05-20 Sareum Ltd Crystalline Forms of a Pharmaceutical Compound
EP4423086A1 (en) 2021-10-25 2024-09-04 Kymera Therapeutics, Inc. Tyk2 degraders and uses thereof

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE794096A (fr) 1972-08-07 1973-05-16 Lepetit Spa Oxazoles 2,4,5-trisubstitues et leur preparation
GB1497536A (en) 1973-12-17 1978-01-12 Lilly Industries Ltd 2-acylaminooxazoles methods for their preparation and their use
DE19653355A1 (de) 1996-12-20 1998-06-25 Dresden Arzneimittel Neue, antikonvulsiv wirkende Aminoimidazole und Verfahren zu ihrer Herstellung
GB0003154D0 (en) 2000-02-12 2000-04-05 Astrazeneca Uk Ltd Novel compounds
NZ522696A (en) 2000-06-28 2004-08-27 Astrazeneca Ab Substituted quinazoline derivatives and their use as inhibitors
MXPA03003868A (es) 2000-10-30 2003-07-28 Janssen Pharmaceutica Nv Inhibidores de tripeptidil peptidasa.
EP1554269A1 (en) 2002-07-09 2005-07-20 Vertex Pharmaceuticals Incorporated Imidazoles, oxazoles and thiazoles with protein kinase inhibiting activities
PL1684750T3 (pl) 2003-10-23 2010-10-29 Ab Science 2-Aminoarylooksazole jako inhibitory kinazy tyrozynowej
GB0504753D0 (en) 2005-03-08 2005-04-13 Astrazeneca Ab Chemical compounds
EP1932833B1 (en) 2005-10-07 2012-08-01 Kissei Pharmaceutical Co., Ltd. Nitrogenated heterocyclic compound and pharmaceutical composition comprising the same
ATE480525T1 (de) 2006-05-12 2010-09-15 Ab Science Neues verfahren zur synthese von 2- aminooxazolverbindungen
US20090093452A1 (en) 2006-08-24 2009-04-09 Pfizer Inc. Pyrrole, Thiophene, Furan, Imidazole, Oxazole, and Thiazole Derivatives
GB0709031D0 (en) 2007-05-10 2007-06-20 Sareum Ltd Pharmaceutical compounds
EP2166846B1 (en) 2007-06-20 2012-10-17 Merck Sharp & Dohme Corp. Inhibitors of janus kinases
EP2278969B1 (en) 2008-04-21 2013-02-13 Merck Sharp & Dohme Corp. Inhibitors of Janus kinases
EP2299816B1 (en) 2008-06-18 2013-11-13 Merck Sharp & Dohme Corp. Inhibitors of janus kinases
CA2730010A1 (en) 2008-07-09 2010-01-14 Merck Sharp & Dohme Corp. Inhibitors of janus kinases
EP2166006A1 (en) 2008-09-18 2010-03-24 Dompe' S.P.A. 2-aryl-propionic acids and derivatives and pharmaceutical compositions containing them
GB0820819D0 (en) 2008-11-13 2008-12-24 Sareum Ltd Pharmaceutical compounds
JP2013522267A (ja) 2010-03-17 2013-06-13 エフ.ホフマン−ラ ロシュ アーゲー イミダゾピリジン化合物、組成物、および使用法
EP2588105A1 (en) 2010-07-01 2013-05-08 Cellzome Limited Triazolopyridines as tyk2 inhibitors
WO2012021611A1 (en) 2010-08-11 2012-02-16 Millennium Pharmaceuticals, Inc. Heteroaryls and uses thereof
WO2013055645A1 (en) 2011-10-12 2013-04-18 Array Biopharma Inc. 5,7-substituted-imidazo[1,2-c]pyrimidines
GB201202027D0 (en) 2012-02-06 2012-03-21 Sareum Ltd Pharmaceutical compounds
DK2634185T3 (en) * 2012-03-02 2016-03-21 Sareum Ltd Tyk2 kinase inhibitors
KR101202026B1 (ko) 2012-07-03 2012-11-16 민호현 황토 석부작 제조 방법
AU2013341186B2 (en) 2012-11-08 2017-03-30 Bristol-Myers Squibb Company Amide-substituted heterocyclic compounds useful as modulators of IL-12, IL-23 and/or IFN alpha responses
CN105793245B (zh) * 2013-09-03 2018-03-20 萨勒姆有限公司 药物化合物
JP6310767B2 (ja) 2014-05-13 2018-04-11 日本電子株式会社 自動分析装置及びノズル洗浄方法
NO2721710T3 (enExample) 2014-08-21 2018-03-31
GB201617871D0 (en) 2016-10-21 2016-12-07 Sareum Limited Pharmaceutical compounds
GB202005114D0 (en) 2020-04-07 2020-05-20 Sareum Ltd Crystalline Forms of a Pharmaceutical Compound

Also Published As

Publication number Publication date
ES3021420T3 (en) 2025-05-26
CA3111049A1 (en) 2020-04-16
MX2021003929A (es) 2021-06-04
BR112021006424A2 (pt) 2021-07-06
EP3864009B1 (en) 2025-02-19
CN113056456B (zh) 2023-06-13
PL3864009T3 (pl) 2025-04-22
CN113056456A (zh) 2021-06-29
FI3864009T3 (fi) 2025-03-24
KR102844196B1 (ko) 2025-08-07
US20210387981A1 (en) 2021-12-16
KR20210076036A (ko) 2021-06-23
US12187716B2 (en) 2025-01-07
JP7383030B2 (ja) 2023-11-17
PT3864009T (pt) 2025-04-23
DK3864009T3 (da) 2025-03-17
IL281599B1 (en) 2024-06-01
WO2020074461A1 (en) 2020-04-16
SG11202102490TA (en) 2021-04-29
IL281599A (en) 2021-05-31
JP2022514799A (ja) 2022-02-15
EP3864009A1 (en) 2021-08-18
IL281599B2 (en) 2024-10-01
AU2019359320A1 (en) 2021-03-18
AU2019359320B2 (en) 2024-04-04

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Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)