DK3864009T3 - Tyk2-kinasehæmmere - Google Patents
Tyk2-kinasehæmmere Download PDFInfo
- Publication number
- DK3864009T3 DK3864009T3 DK19794095.0T DK19794095T DK3864009T3 DK 3864009 T3 DK3864009 T3 DK 3864009T3 DK 19794095 T DK19794095 T DK 19794095T DK 3864009 T3 DK3864009 T3 DK 3864009T3
- Authority
- DK
- Denmark
- Prior art keywords
- kinase inhibitors
- tyk2 kinase
- tyk2
- inhibitors
- kinase
- Prior art date
Links
- 101000844245 Homo sapiens Non-receptor tyrosine-protein kinase TYK2 Proteins 0.000 title 1
- 102100032028 Non-receptor tyrosine-protein kinase TYK2 Human genes 0.000 title 1
- 229940043355 kinase inhibitor Drugs 0.000 title 1
- 239000003757 phosphotransferase inhibitor Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/541—Non-condensed thiazines containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D263/34—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/48—Nitrogen atoms not forming part of a nitro radical
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1816369.1A GB201816369D0 (en) | 2018-10-08 | 2018-10-08 | Pharmaceutical compounds |
| PCT/EP2019/077118 WO2020074461A1 (en) | 2018-10-08 | 2019-10-07 | Tyk2 kinase inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3864009T3 true DK3864009T3 (da) | 2025-03-17 |
Family
ID=64397425
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK19794095.0T DK3864009T3 (da) | 2018-10-08 | 2019-10-07 | Tyk2-kinasehæmmere |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US12187716B2 (enExample) |
| EP (1) | EP3864009B1 (enExample) |
| JP (1) | JP7383030B2 (enExample) |
| KR (1) | KR102844196B1 (enExample) |
| CN (1) | CN113056456B (enExample) |
| AU (1) | AU2019359320B2 (enExample) |
| BR (1) | BR112021006424A2 (enExample) |
| CA (1) | CA3111049A1 (enExample) |
| DK (1) | DK3864009T3 (enExample) |
| ES (1) | ES3021420T3 (enExample) |
| FI (1) | FI3864009T3 (enExample) |
| GB (1) | GB201816369D0 (enExample) |
| IL (1) | IL281599B2 (enExample) |
| MX (1) | MX2021003929A (enExample) |
| PL (1) | PL3864009T3 (enExample) |
| PT (1) | PT3864009T (enExample) |
| SG (1) | SG11202102490TA (enExample) |
| WO (1) | WO2020074461A1 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB202005114D0 (en) * | 2020-04-07 | 2020-05-20 | Sareum Ltd | Crystalline Forms of a Pharmaceutical Compound |
| EP4423086A1 (en) | 2021-10-25 | 2024-09-04 | Kymera Therapeutics, Inc. | Tyk2 degraders and uses thereof |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE794096A (fr) | 1972-08-07 | 1973-05-16 | Lepetit Spa | Oxazoles 2,4,5-trisubstitues et leur preparation |
| GB1497536A (en) | 1973-12-17 | 1978-01-12 | Lilly Industries Ltd | 2-acylaminooxazoles methods for their preparation and their use |
| DE19653355A1 (de) | 1996-12-20 | 1998-06-25 | Dresden Arzneimittel | Neue, antikonvulsiv wirkende Aminoimidazole und Verfahren zu ihrer Herstellung |
| GB0003154D0 (en) | 2000-02-12 | 2000-04-05 | Astrazeneca Uk Ltd | Novel compounds |
| NZ522696A (en) | 2000-06-28 | 2004-08-27 | Astrazeneca Ab | Substituted quinazoline derivatives and their use as inhibitors |
| MXPA03003868A (es) | 2000-10-30 | 2003-07-28 | Janssen Pharmaceutica Nv | Inhibidores de tripeptidil peptidasa. |
| EP1554269A1 (en) | 2002-07-09 | 2005-07-20 | Vertex Pharmaceuticals Incorporated | Imidazoles, oxazoles and thiazoles with protein kinase inhibiting activities |
| PL1684750T3 (pl) | 2003-10-23 | 2010-10-29 | Ab Science | 2-Aminoarylooksazole jako inhibitory kinazy tyrozynowej |
| GB0504753D0 (en) | 2005-03-08 | 2005-04-13 | Astrazeneca Ab | Chemical compounds |
| EP1932833B1 (en) | 2005-10-07 | 2012-08-01 | Kissei Pharmaceutical Co., Ltd. | Nitrogenated heterocyclic compound and pharmaceutical composition comprising the same |
| ATE480525T1 (de) | 2006-05-12 | 2010-09-15 | Ab Science | Neues verfahren zur synthese von 2- aminooxazolverbindungen |
| US20090093452A1 (en) | 2006-08-24 | 2009-04-09 | Pfizer Inc. | Pyrrole, Thiophene, Furan, Imidazole, Oxazole, and Thiazole Derivatives |
| GB0709031D0 (en) | 2007-05-10 | 2007-06-20 | Sareum Ltd | Pharmaceutical compounds |
| EP2166846B1 (en) | 2007-06-20 | 2012-10-17 | Merck Sharp & Dohme Corp. | Inhibitors of janus kinases |
| EP2278969B1 (en) | 2008-04-21 | 2013-02-13 | Merck Sharp & Dohme Corp. | Inhibitors of Janus kinases |
| EP2299816B1 (en) | 2008-06-18 | 2013-11-13 | Merck Sharp & Dohme Corp. | Inhibitors of janus kinases |
| CA2730010A1 (en) | 2008-07-09 | 2010-01-14 | Merck Sharp & Dohme Corp. | Inhibitors of janus kinases |
| EP2166006A1 (en) | 2008-09-18 | 2010-03-24 | Dompe' S.P.A. | 2-aryl-propionic acids and derivatives and pharmaceutical compositions containing them |
| GB0820819D0 (en) | 2008-11-13 | 2008-12-24 | Sareum Ltd | Pharmaceutical compounds |
| JP2013522267A (ja) | 2010-03-17 | 2013-06-13 | エフ．ホフマン−ラ ロシュ アーゲー | イミダゾピリジン化合物、組成物、および使用法 |
| EP2588105A1 (en) | 2010-07-01 | 2013-05-08 | Cellzome Limited | Triazolopyridines as tyk2 inhibitors |
| WO2012021611A1 (en) | 2010-08-11 | 2012-02-16 | Millennium Pharmaceuticals, Inc. | Heteroaryls and uses thereof |
| WO2013055645A1 (en) | 2011-10-12 | 2013-04-18 | Array Biopharma Inc. | 5,7-substituted-imidazo[1,2-c]pyrimidines |
| GB201202027D0 (en) | 2012-02-06 | 2012-03-21 | Sareum Ltd | Pharmaceutical compounds |
| DK2634185T3 (en) * | 2012-03-02 | 2016-03-21 | Sareum Ltd | Tyk2 kinase inhibitors |
| KR101202026B1 (ko) | 2012-07-03 | 2012-11-16 | 민호현 | 황토 석부작 제조 방법 |
| AU2013341186B2 (en) | 2012-11-08 | 2017-03-30 | Bristol-Myers Squibb Company | Amide-substituted heterocyclic compounds useful as modulators of IL-12, IL-23 and/or IFN alpha responses |
| CN105793245B (zh) * | 2013-09-03 | 2018-03-20 | 萨勒姆有限公司 | 药物化合物 |
| JP6310767B2 (ja) | 2014-05-13 | 2018-04-11 | 日本電子株式会社 | 自動分析装置及びノズル洗浄方法 |
| NO2721710T3 (enExample) | 2014-08-21 | 2018-03-31 | ||
| GB201617871D0 (en) | 2016-10-21 | 2016-12-07 | Sareum Limited | Pharmaceutical compounds |
| GB202005114D0 (en) | 2020-04-07 | 2020-05-20 | Sareum Ltd | Crystalline Forms of a Pharmaceutical Compound |
-
2018
- 2018-10-08 GB GBGB1816369.1A patent/GB201816369D0/en not_active Ceased
-
2019
- 2019-10-07 WO PCT/EP2019/077118 patent/WO2020074461A1/en not_active Ceased
- 2019-10-07 ES ES19794095T patent/ES3021420T3/es active Active
- 2019-10-07 CA CA3111049A patent/CA3111049A1/en active Pending
- 2019-10-07 PL PL19794095.0T patent/PL3864009T3/pl unknown
- 2019-10-07 JP JP2021543577A patent/JP7383030B2/ja active Active
- 2019-10-07 KR KR1020217013504A patent/KR102844196B1/ko active Active
- 2019-10-07 DK DK19794095.0T patent/DK3864009T3/da active
- 2019-10-07 BR BR112021006424A patent/BR112021006424A2/pt unknown
- 2019-10-07 US US17/283,151 patent/US12187716B2/en active Active
- 2019-10-07 EP EP19794095.0A patent/EP3864009B1/en active Active
- 2019-10-07 FI FIEP19794095.0T patent/FI3864009T3/fi active
- 2019-10-07 SG SG11202102490TA patent/SG11202102490TA/en unknown
- 2019-10-07 MX MX2021003929A patent/MX2021003929A/es unknown
- 2019-10-07 CN CN201980066166.4A patent/CN113056456B/zh active Active
- 2019-10-07 IL IL281599A patent/IL281599B2/en unknown
- 2019-10-07 AU AU2019359320A patent/AU2019359320B2/en active Active
- 2019-10-07 PT PT197940950T patent/PT3864009T/pt unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES3021420T3 (en) | 2025-05-26 |
| CA3111049A1 (en) | 2020-04-16 |
| MX2021003929A (es) | 2021-06-04 |
| BR112021006424A2 (pt) | 2021-07-06 |
| GB201816369D0 (en) | 2018-11-28 |
| EP3864009B1 (en) | 2025-02-19 |
| CN113056456B (zh) | 2023-06-13 |
| PL3864009T3 (pl) | 2025-04-22 |
| CN113056456A (zh) | 2021-06-29 |
| FI3864009T3 (fi) | 2025-03-24 |
| KR102844196B1 (ko) | 2025-08-07 |
| US20210387981A1 (en) | 2021-12-16 |
| KR20210076036A (ko) | 2021-06-23 |
| US12187716B2 (en) | 2025-01-07 |
| JP7383030B2 (ja) | 2023-11-17 |
| PT3864009T (pt) | 2025-04-23 |
| IL281599B1 (en) | 2024-06-01 |
| WO2020074461A1 (en) | 2020-04-16 |
| SG11202102490TA (en) | 2021-04-29 |
| IL281599A (en) | 2021-05-31 |
| JP2022514799A (ja) | 2022-02-15 |
| EP3864009A1 (en) | 2021-08-18 |
| IL281599B2 (en) | 2024-10-01 |
| AU2019359320A1 (en) | 2021-03-18 |
| AU2019359320B2 (en) | 2024-04-04 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL283639A (en) | Kif18a inhibitors | |
| DK3999506T3 (da) | Parp1-hæmmere | |
| IL290779A (en) | Heterocyclic rip1 kinase inhibitors | |
| IL280593A (en) | Pyrrolopyrimidine itk inhibitors | |
| MA54550A (fr) | Inhibiteurs de kif18a | |
| IL282090A (en) | Tyk2 inhibitors and uses thereof | |
| EP4007756C0 (en) | KIF18A INHIBITORS | |
| DK3788040T3 (da) | Pyridazinoner som parp7-inhibitorer | |
| EP4007753C0 (en) | Kif18a inhibitors | |
| EP3801503A4 (en) | INHIBITORS OF SARM1 | |
| EP3804707A4 (en) | KINASE INHIBITOR | |
| HUE057801T2 (hu) | Aminotriazolopiridinek mint kináz inhibitorok | |
| EP3902805A4 (en) | CYCLINE-DEPENDENT KINASE INHIBITORS | |
| IL276269A (en) | Aminopyrrolotriazines as kinase inhibitors | |
| DK3303334T3 (da) | Tyrosinkinasehæmmere | |
| MA52813A (fr) | Inhibiteurs de sarm1 | |
| MA52809A (fr) | Inhibiteurs de sarm1 | |
| HRP20260058T1 (hr) | Dozni oblici za tyk2 inhibitore | |
| HUE058292T2 (hu) | Aminoimidazopiridazinok mint kináz inhibitorok | |
| DK3783000T3 (da) | Makrocyklisk kinasehæmmer | |
| EP3817736A4 (en) | PIKFYVE INHIBITORS | |
| EP3927700A4 (en) | KINAS INHIBITORS | |
| IL281514A (en) | O-glycoprotein-2-acetamido-2-deoxy-3-d-glucopyranosidase inhibitors | |
| DK3956322T3 (da) | Jak1-selektiv kinaseinhibitor | |
| EP3849985A4 (en) | ALKYNYL NICOTINAMIDE COMPOUNDS AS KINASE INHIBITORS |