SG11202102490TA - Tyk2 kinase inhibitors - Google Patents

Tyk2 kinase inhibitors

Info

Publication number
SG11202102490TA
SG11202102490TA SG11202102490TA SG11202102490TA SG11202102490TA SG 11202102490T A SG11202102490T A SG 11202102490TA SG 11202102490T A SG11202102490T A SG 11202102490TA SG 11202102490T A SG11202102490T A SG 11202102490TA SG 11202102490T A SG11202102490T A SG 11202102490TA
Authority
SG
Singapore
Prior art keywords
kinase inhibitors
tyk2 kinase
tyk2
inhibitors
kinase
Prior art date
Application number
SG11202102490TA
Inventor
John Charles Reader
Original Assignee
Sareum Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sareum Ltd filed Critical Sareum Ltd
Publication of SG11202102490TA publication Critical patent/SG11202102490TA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/34Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/48Nitrogen atoms not forming part of a nitro radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/541Non-condensed thiazines containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SG11202102490TA 2018-10-08 2019-10-07 Tyk2 kinase inhibitors SG11202102490TA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1816369.1A GB201816369D0 (en) 2018-10-08 2018-10-08 Pharmaceutical compounds
PCT/EP2019/077118 WO2020074461A1 (en) 2018-10-08 2019-10-07 Tyk2 kinase inhibitors

Publications (1)

Publication Number Publication Date
SG11202102490TA true SG11202102490TA (en) 2021-04-29

Family

ID=64397425

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202102490TA SG11202102490TA (en) 2018-10-08 2019-10-07 Tyk2 kinase inhibitors

Country Status (13)

Country Link
US (1) US20210387981A1 (en)
EP (1) EP3864009A1 (en)
JP (1) JP7383030B2 (en)
KR (1) KR20210076036A (en)
CN (1) CN113056456B (en)
AU (1) AU2019359320B2 (en)
BR (1) BR112021006424A2 (en)
CA (1) CA3111049A1 (en)
GB (1) GB201816369D0 (en)
IL (1) IL281599A (en)
MX (1) MX2021003929A (en)
SG (1) SG11202102490TA (en)
WO (1) WO2020074461A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB202005114D0 (en) * 2020-04-07 2020-05-20 Sareum Ltd Crystalline Forms of a Pharmaceutical Compound
WO2023076161A1 (en) 2021-10-25 2023-05-04 Kymera Therapeutics, Inc. Tyk2 degraders and uses thereof

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0709031D0 (en) * 2007-05-10 2007-06-20 Sareum Ltd Pharmaceutical compounds
CA2690141A1 (en) 2007-06-20 2008-12-24 Merck Sharp & Dohme Corp. Inhibitors of janus kinases
CA2719847A1 (en) 2008-04-21 2010-01-28 Merck Sharp & Dohme Corp. Inhibitors of janus kinases
CA2727928A1 (en) 2008-06-18 2009-12-23 Merck Sharp & Dohme Corp. Inhibitors of janus kinases
JP2011527680A (en) 2008-07-09 2011-11-04 メルク・シャープ・エンド・ドーム・コーポレイション JANUS kinase inhibitors
GB0820819D0 (en) 2008-11-13 2008-12-24 Sareum Ltd Pharmaceutical compounds
CN102869359A (en) 2010-03-17 2013-01-09 弗·哈夫曼-拉罗切有限公司 Imidazopyridine compounds, compositions and methods of use
EP2588105A1 (en) 2010-07-01 2013-05-08 Cellzome Limited Triazolopyridines as tyk2 inhibitors
EP2634185B1 (en) * 2012-03-02 2016-01-13 Sareum Limited TYK2 kinase inhibitors
KR101202026B1 (en) 2012-07-03 2012-11-16 민호현 Method for manufacturing loess stone-planting
HRP20220766T1 (en) 2012-11-08 2022-09-16 Bristol-Myers Squibb Company Amide-substituted heterocyclic compounds useful as modulators of il-12, il-23 and/or ifn alpha responses
JP6239118B2 (en) 2013-09-03 2017-11-29 サリウム リミテッド Pharmaceutical compounds
NO2721710T3 (en) 2014-08-21 2018-03-31
GB201617871D0 (en) 2016-10-21 2016-12-07 Sareum Limited Pharmaceutical compounds

Also Published As

Publication number Publication date
CN113056456B (en) 2023-06-13
GB201816369D0 (en) 2018-11-28
MX2021003929A (en) 2021-06-04
IL281599A (en) 2021-05-31
AU2019359320B2 (en) 2024-04-04
US20210387981A1 (en) 2021-12-16
CA3111049A1 (en) 2020-04-16
EP3864009A1 (en) 2021-08-18
BR112021006424A2 (en) 2021-07-06
CN113056456A (en) 2021-06-29
WO2020074461A1 (en) 2020-04-16
KR20210076036A (en) 2021-06-23
JP7383030B2 (en) 2023-11-17
JP2022514799A (en) 2022-02-15
AU2019359320A1 (en) 2021-03-18

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