GB201812149D0 - Nucleic acid detection method - Google Patents

Nucleic acid detection method

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Publication number
GB201812149D0
GB201812149D0 GBGB1812149.1A GB201812149A GB201812149D0 GB 201812149 D0 GB201812149 D0 GB 201812149D0 GB 201812149 A GB201812149 A GB 201812149A GB 201812149 D0 GB201812149 D0 GB 201812149D0
Authority
GB
United Kingdom
Prior art keywords
nucleic acid
detection method
acid detection
nucleic
detection
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB1812149.1A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sense Biodetection Ltd
Original Assignee
Sense Biodetection Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sense Biodetection Ltd filed Critical Sense Biodetection Ltd
Priority to GBGB1812149.1A priority Critical patent/GB201812149D0/en
Publication of GB201812149D0 publication Critical patent/GB201812149D0/en
Priority to PCT/GB2019/052089 priority patent/WO2020021272A1/en
Priority to US17/059,927 priority patent/US20210246487A1/en
Priority to GB1910661.6A priority patent/GB2577171B/en
Priority to EP25190042.9A priority patent/EP4647507A3/en
Priority to KR1020217001295A priority patent/KR20210038541A/ko
Priority to CN201980049448.3A priority patent/CN112469833A/zh
Priority to MX2021000946A priority patent/MX2021000946A/es
Priority to EP19748909.9A priority patent/EP3784799B1/en
Priority to ES19748909T priority patent/ES3040542T3/es
Priority to JP2021503732A priority patent/JP7629847B2/ja
Priority to AU2019311340A priority patent/AU2019311340B2/en
Priority to NZ772006A priority patent/NZ772006B2/en
Priority to BR112021000574-9A priority patent/BR112021000574A2/pt
Priority to CA3107388A priority patent/CA3107388A1/en
Priority to US16/773,289 priority patent/US12275991B2/en
Priority to US17/013,810 priority patent/US20210040571A1/en
Priority to ZA2020/07778A priority patent/ZA202007778B/en
Priority to AU2023201422A priority patent/AU2023201422A1/en
Priority to JP2024187527A priority patent/JP2025026849A/ja
Priority to US19/076,978 priority patent/US20250320555A1/en
Priority to US19/076,980 priority patent/US20250283171A1/en
Ceased legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/6853Nucleic acid amplification reactions using modified primers or templates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6827Hybridisation assays for detection of mutation or polymorphism
    • C12Q1/683Hybridisation assays for detection of mutation or polymorphism involving restriction enzymes, e.g. restriction fragment length polymorphism [RFLP]
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    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
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    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6816Hybridisation assays characterised by the detection means
    • CCHEMISTRY; METALLURGY
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    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6834Enzymatic or biochemical coupling of nucleic acids to a solid phase
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
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    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
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    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306Solid-phase reaction mechanisms
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12Q2521/00Reaction characterised by the enzymatic activity
    • C12Q2521/10Nucleotidyl transfering
    • C12Q2521/101DNA polymerase
    • CCHEMISTRY; METALLURGY
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    • C12Q2525/00Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
    • C12Q2525/10Modifications characterised by
    • C12Q2525/101Modifications characterised by incorporating non-naturally occurring nucleotides, e.g. inosine
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    • C12Q2527/00Reactions demanding special reaction conditions
    • C12Q2527/101Temperature
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    • C12Q2531/00Reactions of nucleic acids characterised by
    • C12Q2531/10Reactions of nucleic acids characterised by the purpose being amplify/increase the copy number of target nucleic acid
    • C12Q2531/119Strand displacement amplification [SDA]
    • CCHEMISTRY; METALLURGY
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    • C12Q2563/00Nucleic acid detection characterized by the use of physical, structural and functional properties
    • C12Q2563/107Nucleic acid detection characterized by the use of physical, structural and functional properties fluorescence
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/118Prognosis of disease development
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    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/178Oligonucleotides characterized by their use miRNA, siRNA or ncRNA

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
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  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pathology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
GBGB1812149.1A 2018-07-25 2018-07-25 Nucleic acid detection method Ceased GB201812149D0 (en)

Priority Applications (22)

Application Number Priority Date Filing Date Title
GBGB1812149.1A GB201812149D0 (en) 2018-07-25 2018-07-25 Nucleic acid detection method
CA3107388A CA3107388A1 (en) 2018-07-25 2019-07-25 Nucleic acid detection method
JP2021503732A JP7629847B2 (ja) 2018-07-25 2019-07-25 核酸検出方法
NZ772006A NZ772006B2 (en) 2019-07-25 Nucleic acid detection method
GB1910661.6A GB2577171B (en) 2018-07-25 2019-07-25 Nucleic acid detection method utilising primers and probes
EP25190042.9A EP4647507A3 (en) 2018-07-25 2019-07-25 Nucleic acid detection method
KR1020217001295A KR20210038541A (ko) 2018-07-25 2019-07-25 핵산 검출 방법
CN201980049448.3A CN112469833A (zh) 2018-07-25 2019-07-25 核酸检测方法
MX2021000946A MX2021000946A (es) 2018-07-25 2019-07-25 Metodo de deteccion de acido nucleico.
EP19748909.9A EP3784799B1 (en) 2018-07-25 2019-07-25 Nucleic acid detection method
ES19748909T ES3040542T3 (en) 2018-07-25 2019-07-25 Nucleic acid detection method
PCT/GB2019/052089 WO2020021272A1 (en) 2018-07-25 2019-07-25 Nucleic acid detection method
AU2019311340A AU2019311340B2 (en) 2018-07-25 2019-07-25 Nucleic acid detection method
US17/059,927 US20210246487A1 (en) 2018-07-25 2019-07-25 Nucleic acid detection method
BR112021000574-9A BR112021000574A2 (pt) 2018-07-25 2019-07-25 Método de detecção de ácido nucleico
US16/773,289 US12275991B2 (en) 2018-07-25 2020-01-27 Nucleic acid detection method
US17/013,810 US20210040571A1 (en) 2018-07-25 2020-09-07 Nucleic acid detection method
ZA2020/07778A ZA202007778B (en) 2018-07-25 2020-12-14 Nucleic acid detection method
AU2023201422A AU2023201422A1 (en) 2018-07-25 2023-03-07 Nucleic acid detection method
JP2024187527A JP2025026849A (ja) 2018-07-25 2024-10-24 核酸検出方法
US19/076,978 US20250320555A1 (en) 2018-07-25 2025-03-11 Nucleic acid detection method
US19/076,980 US20250283171A1 (en) 2018-07-25 2025-03-11 Nucleic acid detection method

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1812149.1A GB201812149D0 (en) 2018-07-25 2018-07-25 Nucleic acid detection method

Publications (1)

Publication Number Publication Date
GB201812149D0 true GB201812149D0 (en) 2018-09-05

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ID=63364368

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GBGB1812149.1A Ceased GB201812149D0 (en) 2018-07-25 2018-07-25 Nucleic acid detection method
GB1910661.6A Active GB2577171B (en) 2018-07-25 2019-07-25 Nucleic acid detection method utilising primers and probes

Family Applications After (1)

Application Number Title Priority Date Filing Date
GB1910661.6A Active GB2577171B (en) 2018-07-25 2019-07-25 Nucleic acid detection method utilising primers and probes

Country Status (13)

Country Link
US (4) US20210246487A1 (https=)
EP (2) EP4647507A3 (https=)
JP (2) JP7629847B2 (https=)
KR (1) KR20210038541A (https=)
CN (1) CN112469833A (https=)
AU (2) AU2019311340B2 (https=)
BR (1) BR112021000574A2 (https=)
CA (1) CA3107388A1 (https=)
ES (1) ES3040542T3 (https=)
GB (2) GB201812149D0 (https=)
MX (1) MX2021000946A (https=)
WO (1) WO2020021272A1 (https=)
ZA (1) ZA202007778B (https=)

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Publication number Priority date Publication date Assignee Title
GB201611469D0 (en) 2016-06-30 2016-08-17 Lumiradx Tech Ltd Improvements in or relating to nucleic acid amplification processes
GB2569965A (en) 2018-01-04 2019-07-10 Lumiradx Uk Ltd Improvements in or relating to amplification of nucleic acids
US20210040571A1 (en) * 2018-07-25 2021-02-11 Sense Biodetection Limited Nucleic acid detection method
GB201812149D0 (en) * 2018-07-25 2018-09-05 Sense Biodetection Ltd Nucleic acid detection method
EP4196787A1 (en) 2020-08-11 2023-06-21 Zoetis Services LLC Lateral flow device for detecting sars-cov-2 antibodies in human and animal samples
JP2023539299A (ja) 2020-08-26 2023-09-13 センス バイオディテクション リミテッド デバイス
WO2022043697A1 (en) 2020-08-26 2022-03-03 Sense Biodetection Limited Devices
CN113624980B (zh) * 2021-08-09 2023-06-13 四川大学华西医院 基于识别诱导的恒温扩增技术对蛋白质进行检测的方法及试剂盒
CN114107510B (zh) * 2021-12-10 2023-10-03 湖南工程学院 基于dna三链介导构建多维dna酶矩阵的超灵敏循环核酸检测体系、试剂盒和方法
CN117568446A (zh) * 2022-08-08 2024-02-20 台达电子国际(新加坡)私人有限公司 检测病毒感染性的样本前处理试剂盒及方法
CN116162693B (zh) * 2022-08-12 2025-08-01 浙江大学 一种检测阿尔茨海默病致病基因突变和apoe基因型的引物组合及试剂盒
CN115747322B (zh) * 2022-08-12 2025-08-01 浙江大学 一种恒温多重扩增检测肝豆状核变性atp7b基因高频突变位点基因分型的检测方法
WO2024072805A1 (en) * 2022-09-26 2024-04-04 Lau, Johnson Yiu-Nam Compositions, systems, and methods for detection of ovarian cancer
WO2024080776A1 (ko) * 2022-10-14 2024-04-18 고려대학교 산학협력단 비색 검출을 위한 황 함유 프로브 및 핵산 내 황 도입을 통한 효소 활성 가속화 방법
CN116536400A (zh) * 2023-04-06 2023-08-04 广州迪澳基因科技有限公司 一种高特异性等温核酸扩增方法
CN117046441B (zh) * 2023-08-14 2024-04-02 中国科学院生态环境研究中心 磁性氧化石墨烯粒子、制备方法及其应用
WO2025255157A1 (en) * 2024-06-04 2025-12-11 President And Fellows Of Harvard College Systems, methods, and compositions for protein screening
WO2026015653A2 (en) 2024-07-09 2026-01-15 Sherlock Biosciences, Inc. Power-free fluidic device

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