|
US5981481A
(en)
*
|
1974-12-06 |
1999-11-09 |
The Johns Hopkins University |
Human C3b/C4b receptor (CR1)
|
|
JPH0742235B2
(ja)
|
1985-11-08 |
1995-05-10 |
三共株式会社 |
自己免疫性疾病の予防・治療剤
|
|
DE3600368C1
(de)
|
1986-01-09 |
1987-04-02 |
Goldschmidt Ag Th |
Trennmittel fuer Polyurethanformteile
|
|
IL89790A
(en)
|
1988-04-01 |
2002-05-23 |
Johns Hopking University |
Nucleic acid sequences that encode and cells that produce cr1 protein and methods of production and purification
|
|
US6458360B1
(en)
|
1990-04-25 |
2002-10-01 |
The Johns Hopkins University |
Soluble complement regulatory molecules
|
|
CA2097825A1
(en)
|
1990-12-06 |
1992-06-07 |
Henry C. Marsh, Jr. |
Synergistic compositions of soluble complement receptors and compounds that inhibit complement and/or suppress immune activity
|
|
EP0649468B1
(en)
|
1992-06-24 |
2000-03-15 |
AdProTech plc |
Soluble cr1 derivatives
|
|
GB9301289D0
(en)
|
1993-01-22 |
1993-03-17 |
Smithkline Beecham Plc |
Novel composition
|
|
US5679546A
(en)
|
1993-09-24 |
1997-10-21 |
Cytomed, Inc. |
Chimeric proteins which block complement activation
|
|
US5648244A
(en)
|
1993-09-27 |
1997-07-15 |
President And Fellows Of Harvard College |
Production, purification, cleavage and use of fusion peptides
|
|
WO1999044625A1
(en)
|
1998-03-03 |
1999-09-10 |
John Hopkins University |
Smallpox inhibitor of complement enzymes (spice) protein and methods of inhibiting complement activation
|
|
WO2000061752A2
(en)
|
1999-04-09 |
2000-10-19 |
Washington University |
Modified complement system regulators
|
|
US20030049831A1
(en)
|
2000-03-13 |
2003-03-13 |
Murphy Brendan F. |
Novel factor-H related protein 5 and antibodies thereto
|
|
US20030086940A1
(en)
|
2001-08-10 |
2003-05-08 |
Cristina Costa |
Engineered recombinant molecule that regulates humoral and cellular effector functions of the immune system
|
|
MXPA05003493A
(es)
|
2002-10-02 |
2005-09-30 |
Catalyst Biosciences |
Metodos para generar y seleccionar proteasas con especificidad alterada.
|
|
WO2004075838A2
(en)
|
2003-02-21 |
2004-09-10 |
Rikshospitalet-Radiumhospitalet Hf |
Method and compositions for the treatment of meconium aspiration syndrome
|
|
EP1601377A4
(en)
|
2003-02-21 |
2009-07-15 |
Genentech Inc |
METHOD FOR THE PREVENTION AND TREATMENT OF TISSUE DAMAGE IN CONNECTION WITH ISCHEMIC REPERFUSION DAMAGE
|
|
WO2004103294A2
(en)
|
2003-05-15 |
2004-12-02 |
Tanox, Inc. |
Methods and compositions for the prevention and treatment of sepsis
|
|
WO2005014849A2
(en)
|
2003-07-03 |
2005-02-17 |
Euro-Celtique, S.A. |
Genes associated with responses to neuropathic pain
|
|
US7556814B2
(en)
|
2003-10-23 |
2009-07-07 |
Karp Nelson M |
Immunogenic compositions comprising UV-irradiated, psoralen-inactivated, desialated human immunodeficiency virus (HIV) devoid of CD55 and CD59 in the viral membrane
|
|
US8124097B2
(en)
*
|
2004-01-21 |
2012-02-28 |
Case Western Reserve University |
Hybrid and chimeric polypeptides that regulate activation of complement
|
|
JP2005211063A
(ja)
|
2004-01-30 |
2005-08-11 |
Junko Maekuroshima |
ブレンドノニ茶
|
|
US20050169921A1
(en)
|
2004-02-03 |
2005-08-04 |
Leonard Bell |
Method of treating hemolytic disease
|
|
US20050277158A1
(en)
|
2004-06-10 |
2005-12-15 |
Ge Chen |
Method and kit for donor specific complement-fixing antibodies crossmatch
|
|
EP1814576A2
(en)
|
2004-07-20 |
2007-08-08 |
Critical Therapeutics, Inc. |
Combination therapies of hmgb and complement inhibitors against inflammation
|
|
US8088579B2
(en)
|
2005-02-14 |
2012-01-03 |
University Of Iowa Research Foundation |
Complement factor H for diagnosis of age-related macular degeneration
|
|
WO2006120160A1
(en)
|
2005-05-06 |
2006-11-16 |
Laboratoires Serono S.A. |
Use of an immunoglobulin domain-containing cell surface recognition molecule for treating diseases
|
|
MX2008004693A
(es)
|
2005-10-21 |
2008-09-03 |
Catalyst Biosciences Inc |
Proteasas modificadas que inhiben la activacion del complemento.
|
|
PT2500030E
(pt)
|
2005-11-04 |
2015-09-24 |
Genentech Inc |
Uso de inibidores da via do complemento para tratar doenças oculares
|
|
PT2044111E
(pt)
|
2006-06-21 |
2014-11-12 |
Univ Colorado Regents |
Abordagem seletiva do fator h do complemento para o tratamento de doenças
|
|
ATE495447T1
(de)
|
2006-07-03 |
2011-01-15 |
Univ Johns Hopkins |
Peptidantikörperdepletion und anwendung zur probenvorbereitung für massenspektrometrie
|
|
WO2008008986A2
(en)
|
2006-07-13 |
2008-01-17 |
University Of Iowa Research Foundation |
Methods and reagents for treatment and diagnosis of vascular disorders and age-related macular degeneration
|
|
US8664176B2
(en)
|
2006-10-20 |
2014-03-04 |
Celldex Therapeutics, Inc. |
Treatment for age-related macular degeneration and other diseases of the eye
|
|
PL2907827T3
(pl)
|
2006-11-02 |
2019-03-29 |
Genentech, Inc. |
Humanizowane przeciwciała przeciw czynnikowi D i ich zastosowanie
|
|
GB0701213D0
(en)
|
2007-01-23 |
2007-02-28 |
Univ Cardiff |
Factor H polymorphisms in the diagnosis and therapy of inflammatory diseases such as age-related macular degeneration
|
|
NZ578873A
(en)
|
2007-03-01 |
2012-01-12 |
Wellstat Ophthalmics Corp |
Complement factor B analogs and uses for the treatment of complement mediated disease such as inflammation
|
|
GB2447696A
(en)
|
2007-03-23 |
2008-09-24 |
Univ Exeter |
Photonic biosensor arrays
|
|
GB2447698A
(en)
|
2007-03-23 |
2008-09-24 |
Univ Exeter |
Fabrication of photonic biosensor arrays
|
|
KR101572700B1
(ko)
*
|
2007-06-07 |
2015-11-30 |
제넨테크, 인크. |
보체-관련 장애의 예방 및 치료를 위한 C3b 항체 및 방법
|
|
WO2009022246A1
(en)
|
2007-08-10 |
2009-02-19 |
Koninklijke Philips Electronics N.V. |
Sensor array for spr-based detection.
|
|
US20100324154A1
(en)
|
2007-11-01 |
2010-12-23 |
Hageman Gregory S |
Assessing susceptibility to vascular disorders
|
|
AR069130A1
(es)
|
2007-11-02 |
2009-12-30 |
Novartis Ag |
Moleculas de enlace de la opsonina principal del complemento (c3b) y metodos para modular el componente de complemento
|
|
WO2009121065A2
(en)
|
2008-03-28 |
2009-10-01 |
Apellis Ag |
Modulation and repletion/enhancement of the complement system for treatment of trauma
|
|
CR20170001A
(es)
|
2008-04-28 |
2017-08-10 |
Genentech Inc |
Anticuerpos anti factor d humanizados
|
|
US20090324585A1
(en)
|
2008-06-12 |
2009-12-31 |
The Trustees of the Leland Standford Junior University |
Complement inhibitory agents as therapeutics in posttraumatic and degenerative arthritis
|
|
WO2010027872A1
(en)
|
2008-08-27 |
2010-03-11 |
Children's Hospital & Research Center At Oakland |
Complement factor h-based assays for serum bactericidal activity against neisseria meningitidis
|
|
GB0815576D0
(en)
|
2008-08-28 |
2008-10-01 |
Lucas & Co |
Analysis of glycated proteins
|
|
US8937046B2
(en)
|
2008-09-22 |
2015-01-20 |
The Regents Of The University Of Colorado, A Body Corporate |
Modulating the alternative complement pathway
|
|
US9447176B2
(en)
|
2008-11-10 |
2016-09-20 |
Alexion Pharmaceuticals, Inc. |
Methods and compositions for treating complement-associated disorders
|
|
WO2010056399A1
(en)
|
2008-11-17 |
2010-05-20 |
Incode Biopharmaceutics, Inc. |
Method and composition for modulating the immune system and various inflammatory conditions comprising complement depletors
|
|
AU2010306581B2
(en)
|
2009-10-16 |
2015-03-19 |
Omeros Corporation |
Methods for treating disseminated intravascular coagulation by inhibiting MASP-2 dependent complement activation
|
|
EP2496259B1
(en)
|
2009-11-05 |
2017-02-22 |
Alexion Pharmaceuticals, Inc. |
Treatment of paroxysmal nocturnal hemoglobinuria
|
|
GB0922659D0
(en)
|
2009-12-24 |
2010-02-10 |
Univ Edinburgh |
Factor H
|
|
CA2791962A1
(en)
|
2010-03-01 |
2011-09-09 |
Alexion Pharmaceuticals, Inc. |
Methods and compositions for treating degos' disease
|
|
US9815876B2
(en)
|
2010-03-05 |
2017-11-14 |
Omeros Corporation |
Chimeric inhibitor molecules of complement activation
|
|
CA2800526C
(en)
|
2010-04-22 |
2018-03-13 |
Ryan Cameron Denomme |
Method and apparatus for an interferometric localized surface plasmon resonance (ilspr) sensor
|
|
JP5986990B2
(ja)
|
2010-05-14 |
2016-09-06 |
ザ リージェンツ オブ ザ ユニヴァーシティ オブ コロラド,ア ボディ コーポレート |
改善された補体レセプター2(cr2)ターゲティング基
|
|
MX2012014975A
(es)
|
2010-06-22 |
2013-03-12 |
Univ Colorado Regents |
Anticuerpos al fragmento c3d de componente 3 de complemento.
|
|
CN103237557A
(zh)
|
2010-09-15 |
2013-08-07 |
赛尔戴克斯治疗公司 |
用可溶性I型补体受体(sCR1)治疗慢性肾病
|
|
MX348025B
(es)
|
2010-11-01 |
2017-05-24 |
Genentech Inc * |
Prediccion del paso a degeneracion macular avanzada relacionada con la edad utilizando una puntuacion poligenica.
|
|
WO2012095519A1
(en)
|
2011-01-13 |
2012-07-19 |
Leibniz-Institut Für Naturstoff-Forschung Und Infektionsbiologie |
Potent inhibitors of complement activation
|
|
CN107638565B
(zh)
|
2011-04-08 |
2021-12-21 |
莱斯特大学 |
用于治疗与masp-2依赖性补体活化相关的状况的方法
|
|
JP6138815B2
(ja)
*
|
2011-12-01 |
2017-05-31 |
エーピー バイオサイエンシーズ, インコーポレイテッド |
補体経路およびvegf経路に対するタンパク質インヒビターおよびそれらの使用方法
|
|
WO2013151663A1
(en)
*
|
2012-04-02 |
2013-10-10 |
modeRNA Therapeutics |
Modified polynucleotides for the production of membrane proteins
|
|
WO2013185069A1
(en)
|
2012-06-08 |
2013-12-12 |
Shire Human Genetic Therapies, Inc. |
Pulmonary delivery of mrna to non-lung target cells
|
|
EP2929035A1
(en)
|
2012-12-07 |
2015-10-14 |
Shire Human Genetic Therapies, Inc. |
Lipidic nanoparticles for mrna delivering
|
|
CA2899034A1
(en)
|
2013-01-23 |
2014-07-31 |
Musc Foundation For Research Development |
Targeting constructs based on natural antibodies and uses thereof
|
|
GB201301632D0
(en)
|
2013-01-30 |
2013-03-13 |
Imp Innovations |
Complement System
|
|
ME03043B
(me)
|
2013-03-14 |
2018-10-20 |
Alnylam Pharmaceuticals Inc |
Irnk sastavi komponente komplementa c5 i metode za njihovu upotrebu
|
|
WO2014194213A1
(en)
|
2013-05-30 |
2014-12-04 |
University Of Iowa Research Foundation |
Specific complement proteins and efficacy of antibody therapy
|
|
WO2014197885A2
(en)
|
2013-06-07 |
2014-12-11 |
Duke University |
Inhibitors of complement factor h
|
|
US20160184391A1
(en)
|
2013-08-16 |
2016-06-30 |
Alexion Pharmaceuticals, Inc. |
Treatment of graft rejection by administering a complement inhibitor to an organ prior to transplant
|
|
CN104231085B
(zh)
|
2013-09-05 |
2017-03-15 |
复旦大学附属肿瘤医院 |
靶向特异性补体系统抑制剂、其制备方法及应用
|
|
GB201318170D0
(en)
|
2013-10-14 |
2013-11-27 |
Univ Edinburgh |
Proteins with Diagnostic and Therapeutic Uses
|
|
WO2015061467A1
(en)
|
2013-10-22 |
2015-04-30 |
Shire Human Genetic Therapies, Inc. |
Lipid formulations for delivery of messenger rna
|
|
FR3015484A1
(fr)
*
|
2013-12-20 |
2015-06-26 |
Lab Francais Du Fractionnement |
Proteines recombinantes possedant une activite de facteur h
|
|
EP3177732A4
(en)
|
2014-08-08 |
2018-04-25 |
ModernaTX, Inc. |
Compositions and methods for the treatment of ophthalmic diseases and conditions
|
|
IL250667B2
(en)
|
2014-08-20 |
2023-10-01 |
Stichting Sanquin Bloedvoorziening |
Factor h potentiating antibodies and uses thereof
|
|
US20180280447A1
(en)
|
2014-10-29 |
2018-10-04 |
Sungkwang Medical Foundation |
Placenta-derived cells excreting c3 or c1r complement and composition containing same
|
|
US20210318287A1
(en)
|
2015-02-16 |
2021-10-14 |
The Regents Of The University Of Michigan |
Localized surface plasmon resonance sensor systems and methods
|
|
KR102789821B1
(ko)
|
2015-03-31 |
2025-04-02 |
소리소 파마슈티컬스 인크. |
프로테아제-절단가능 링커를 갖는 펩티드 구조물
|
|
EP3359663A4
(en)
*
|
2015-09-24 |
2019-08-14 |
The Trustees of The University of Pennsylvania |
COMPOSITION AND METHOD FOR THE TREATMENT OF A COMPLEMENT-MEDIATED DISEASE
|
|
SG11201808440YA
(en)
|
2016-04-15 |
2018-10-30 |
Regenxbio Inc |
Treatment of ocular diseases with fully-human post-translationally modified anti-vegf fab
|
|
GB201608046D0
(en)
*
|
2016-05-09 |
2016-06-22 |
Cambridge Entpr Ltd And Syndey Children S Hospitals Network Randwick And Westmead Incorporating The |
Treatment of complement-mediated disorders
|
|
KR102566634B1
(ko)
*
|
2016-06-28 |
2023-08-14 |
우니베르시테트 울름 |
보체 억제제 및 그의 용도
|
|
GB201709222D0
(en)
|
2017-06-09 |
2017-07-26 |
Univ Manchester |
C3b Inactivating Polypeptide
|
|
JP7295841B2
(ja)
|
2017-07-25 |
2023-06-21 |
バイオコン・リミテッド |
インスリン&インスリン類似体の配列の同定のためのペプチドマッピング方法
|
|
GB201800620D0
(en)
|
2018-01-15 |
2018-02-28 |
Univ Manchester |
C3b Binding Polypeptide
|
|
MX2020009458A
(es)
|
2018-03-13 |
2020-10-12 |
Amgen Inc |
Digestion secuencial de polipeptidos para analisis espectrometrico de masas.
|
|
CN112470003A
(zh)
|
2018-05-10 |
2021-03-09 |
曼彻斯特大学 |
评估黄斑变性的方法
|
|
AU2019268410B2
(en)
|
2018-05-16 |
2025-01-02 |
Csl Limited |
Soluble complement receptor type 1 variants and uses thereof
|
|
GB2583560A
(en)
|
2018-12-11 |
2020-11-04 |
Admirx Inc |
Fusion protein constructs for complement associated disease
|
|
GB201821082D0
(en)
|
2018-12-21 |
2019-02-06 |
Gyroscope Therapeutics Ltd |
Combination of complement factors i and h, and vector encoding thereof
|
|
CN114072425A
(zh)
|
2019-06-12 |
2022-02-18 |
杰特创新股份有限公司 |
可溶性补体受体1型变体缀合物及其用途
|
|
GB202006789D0
(en)
|
2020-05-07 |
2020-06-24 |
Univ Manchester |
Detection of complement proteins
|
|
GB202007353D0
(en)
|
2020-05-18 |
2020-07-01 |
Shaw Andrew |
Viral infection characterization
|
|
US20210373009A1
(en)
|
2020-05-28 |
2021-12-02 |
University Of North Texas |
Plasmonic meta-surface based molecular sensors and methods for making and using them
|
|
WO2022079453A1
(en)
|
2020-10-16 |
2022-04-21 |
Gyroscope Therapeutics Limited |
Nucleic acid encoding an anti-vegf entity and a negative complement regulator and uses thereof for the treatment of age-related macular degeneration
|