GB201501593D0 - New compounds and processes - Google Patents

New compounds and processes

Info

Publication number
GB201501593D0
GB201501593D0 GBGB1501593.6A GB201501593A GB201501593D0 GB 201501593 D0 GB201501593 D0 GB 201501593D0 GB 201501593 A GB201501593 A GB 201501593A GB 201501593 D0 GB201501593 D0 GB 201501593D0
Authority
GB
United Kingdom
Prior art keywords
processes
new compounds
compounds
new
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB1501593.6A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nobel Chemicals AB
Original Assignee
Cambrex Karlskoga AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cambrex Karlskoga AB filed Critical Cambrex Karlskoga AB
Priority to GBGB1501593.6A priority Critical patent/GB201501593D0/en
Publication of GB201501593D0 publication Critical patent/GB201501593D0/en
Priority to PL16706396T priority patent/PL3250556T3/pl
Priority to PCT/GB2016/050204 priority patent/WO2016120635A1/en
Priority to KR1020177023707A priority patent/KR102458638B1/ko
Priority to US15/547,288 priority patent/US10053420B2/en
Priority to CN201680012547.0A priority patent/CN107428648B/zh
Priority to ES16706396T priority patent/ES2716748T3/es
Priority to HRP20190286TT priority patent/HRP20190286T1/hr
Priority to TR2019/02673T priority patent/TR201902673T4/tr
Priority to EP16706396.5A priority patent/EP3250556B1/en
Priority to HUE16706396A priority patent/HUE042626T2/hu
Priority to DK16706396.5T priority patent/DK3250556T3/en
Priority to JP2017540562A priority patent/JP6702623B2/ja
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/01—Sulfonic acids
    • C07C309/02—Sulfonic acids having sulfo groups bound to acyclic carbon atoms
    • C07C309/24—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of a carbon skeleton containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/455—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation with carboxylic acids or their derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C249/00—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C249/02—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of compounds containing imino groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/62—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by hydrogenation of carbon-to-carbon double or triple bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/63—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/78—Separation; Purification; Stabilisation; Use of additives
    • C07C45/86—Use of additives, e.g. for stabilisation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C07D233/58—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/14—Esters of phosphoric acids containing P(=O)-halide groups
    • C07F9/1403—Esters of phosphoric acids containing P(=O)-halide groups containing the structure Hal-P(=O)-O-unsaturated acyclic group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00—Compounds having —CHO groups
    • C07C47/20—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms
    • C07C47/228—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing six-membered aromatic rings, e.g. phenylacetaldehyde
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00—Compounds having —CHO groups
    • C07C47/20—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms
    • C07C47/228—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing six-membered aromatic rings, e.g. phenylacetaldehyde
    • C07C47/232—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing six-membered aromatic rings, e.g. phenylacetaldehyde having unsaturation outside the aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00—Compounds having —CHO groups
    • C07C47/20—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms
    • C07C47/24—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Plural Heterocyclic Compounds (AREA)
GBGB1501593.6A 2015-01-30 2015-01-30 New compounds and processes Ceased GB201501593D0 (en)

Priority Applications (13)

Application Number Priority Date Filing Date Title
GBGB1501593.6A GB201501593D0 (en) 2015-01-30 2015-01-30 New compounds and processes
JP2017540562A JP6702623B2 (ja) 2015-01-30 2016-01-29 メデトミジンの合成に有用な３−アリールブタナールなどの化合物の調製方法
ES16706396T ES2716748T3 (es) 2015-01-30 2016-01-29 Procedimientos de preparación de compuestos, tales como 3-arilbutanales, útiles en la síntesis de medetomidina
PCT/GB2016/050204 WO2016120635A1 (en) 2015-01-30 2016-01-29 Processes for the preparation of compounds, such as 3-arylbutanals, useful in the synthesis of medetomidine
KR1020177023707A KR102458638B1 (ko) 2015-01-30 2016-01-29 메데토미딘의 합성에서 유용한 3-아릴부탄알과 같은 화합물의 제조 방법
US15/547,288 US10053420B2 (en) 2015-01-30 2016-01-29 Processes for the preparation of compounds, such as 3-arylbutanals, useful in the synthesis of medetomidine
CN201680012547.0A CN107428648B (zh) 2015-01-30 2016-01-29 用于制备可用于合成美托咪定的诸如3-芳基丁醛的化合物的方法
PL16706396T PL3250556T3 (pl) 2015-01-30 2016-01-29 Sposoby otrzymywania związków, takich jak 3-arylobutanale, stosowanych w syntezie medetomidyny
HRP20190286TT HRP20190286T1 (hr) 2015-01-30 2016-01-29 Postupci za pripremu spojeva, kao što su 3-arilbutanali, korisni u sintezi medetomidina
TR2019/02673T TR201902673T4 (tr) 2015-01-30 2016-01-29 Medetomidin sentezinde yararlı olan 3-arilbütanlar gibi bileşiklerin hazırlanması için işlemler.
EP16706396.5A EP3250556B1 (en) 2015-01-30 2016-01-29 Processes for the preparation of compounds, such as 3-arylbutanals, useful in the synthesis of medetomidine
HUE16706396A HUE042626T2 (hu) 2015-01-30 2016-01-29 Eljárások a medetomidin szintézisnél hasznosítható vegyületek, például 3 aril-butiral-dehidek elõállítására
DK16706396.5T DK3250556T3 (en) 2015-01-30 2016-01-29 PROCEDURES FOR THE PREPARATION OF COMPOUNDS, SUCH AS 3-ARYL BUTANALS THAT CAN BE USED FOR THE SYNTHESIS OF MEDETOMIDINE

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1501593.6A GB201501593D0 (en) 2015-01-30 2015-01-30 New compounds and processes

Publications (1)

Publication Number Publication Date
GB201501593D0 true GB201501593D0 (en) 2015-03-18

Family

ID=52705534

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB1501593.6A Ceased GB201501593D0 (en) 2015-01-30 2015-01-30 New compounds and processes

Country Status (13)

Country Link
US (1) US10053420B2 (enExample)
EP (1) EP3250556B1 (enExample)
JP (1) JP6702623B2 (enExample)
KR (1) KR102458638B1 (enExample)
CN (1) CN107428648B (enExample)
DK (1) DK3250556T3 (enExample)
ES (1) ES2716748T3 (enExample)
GB (1) GB201501593D0 (enExample)
HR (1) HRP20190286T1 (enExample)
HU (1) HUE042626T2 (enExample)
PL (1) PL3250556T3 (enExample)
TR (1) TR201902673T4 (enExample)
WO (1) WO2016120635A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12050293B2 (en) 2018-12-19 2024-07-30 Pgs Geophysical As Medetomidine compositions having improved anti-fouling characteristics
PT4038149T (pt) 2020-10-21 2023-05-29 I Tech Ab Compostos anti-incrustação
EP4506340A1 (en) * 2022-03-22 2025-02-12 Obshestvo s Ogranichennoj Otvetstvennostju "Vikzdorove Zhivotnyh" Method for producing medetomidine and its derivatives
WO2026015064A1 (en) 2024-07-09 2026-01-15 I-Tech Ab Antifouling paint composition with improved in-can stability

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2340812C2 (de) 1973-08-11 1982-05-27 Basf Ag, 6700 Ludwigshafen Phenylpropanale sowie ein Verfahren zu deren Herstellung
US4416902A (en) 1982-07-16 1983-11-22 International Flavors & Fragrances Inc. Flavoring with cyclohexenyl-beta-methyl acrolein derivatives
DE19714042A1 (de) 1997-04-05 1998-10-08 Henkel Kgaa Verfahren zur Herstellung aromatischer Aldehyde
WO2007111630A1 (en) * 2005-07-29 2007-10-04 Flexitral, Inc. Compounds which release an odor on a change in ph
CN102458659B (zh) * 2009-06-03 2014-07-09 高砂香料工业株式会社 不对称氢化催化剂
TW201223934A (en) 2010-11-26 2012-06-16 Lonza Ag 3-(2,3-dimethylphenyl)-2-butenal and its use as perfume
WO2012098067A1 (en) * 2011-01-19 2012-07-26 Dsm Ip Assets B.V. Preparation of 4-acetoxy-2-methylbutanal by catalytic carbon carbon double bond hydrogenation
TW201238603A (en) * 2011-03-10 2012-10-01 Lonza Ag Method for preparation of 3-(2,3-dimethylphenyl)-2-butenal
IN2014DN00144A (enExample) * 2011-07-22 2015-05-22 Cambrex Karlskoga Ab
WO2012172120A2 (en) * 2012-05-08 2012-12-20 Lonza Ltd 2-(2,3-dimethylphenyl)-1-propanal and its use as perfume
JP5777840B2 (ja) * 2012-05-08 2015-09-09 ロンザ・リミテッド ２−（２，３−ジメチルフェニル）−１−プロパナールを調製するための方法
WO2012172119A2 (en) * 2012-05-08 2012-12-20 Lonza Ltd Method for the preparation of medetomidine

Also Published As

Publication number Publication date
JP6702623B2 (ja) 2020-06-03
KR102458638B1 (ko) 2022-10-24
KR20170108080A (ko) 2017-09-26
HUE042626T2 (hu) 2019-07-29
PL3250556T3 (pl) 2019-05-31
US10053420B2 (en) 2018-08-21
CN107428648B (zh) 2021-12-10
EP3250556A1 (en) 2017-12-06
CN107428648A (zh) 2017-12-01
JP2018505179A (ja) 2018-02-22
WO2016120635A1 (en) 2016-08-04
HRP20190286T1 (hr) 2019-04-05
DK3250556T3 (en) 2019-03-11
TR201902673T4 (tr) 2019-03-21
EP3250556B1 (en) 2018-12-05
ES2716748T3 (es) 2019-06-14
US20180009744A1 (en) 2018-01-11

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Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)