GB201311361D0 - Compounds and their therapeutic use - Google Patents
Compounds and their therapeutic useInfo
- Publication number
- GB201311361D0 GB201311361D0 GBGB1311361.8A GB201311361A GB201311361D0 GB 201311361 D0 GB201311361 D0 GB 201311361D0 GB 201311361 A GB201311361 A GB 201311361A GB 201311361 D0 GB201311361 D0 GB 201311361D0
- Authority
- GB
- United Kingdom
- Prior art keywords
- compounds
- therapeutic use
- therapeutic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 150000001875 compounds Chemical class 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
- C07C311/20—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/61—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Dermatology (AREA)
- Vascular Medicine (AREA)
- Pain & Pain Management (AREA)
- Urology & Nephrology (AREA)
- Oncology (AREA)
- Diabetes (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (32)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1311361.8A GB201311361D0 (en) | 2013-06-26 | 2013-06-26 | Compounds and their therapeutic use |
| CA2915075A CA2915075C (en) | 2013-06-26 | 2014-06-24 | N-(4-hydroxy-4-methyl-cyclohexyl)-4-phenyl-benzenesulfonamides and n-(4-hydroxy-4-methyl-cyclohexyl)-4-(2-pyridyl)benzenesulfonamides and their therapeutic use |
| DK14735642.2T DK3013799T3 (en) | 2013-06-26 | 2014-06-24 | N- (4-HYDROXY-4-METHYL-CYCLOHEXYL) -4-PHENYL-BENZENESULPHONAMIDES AND N- (4-HYDROXY-4-METHYL-CYCLOHEXYL) -4- (2-PYRIDYL) -BENZENESULPHONAMIDES AND THEIR THERAPEES |
| HRP20171611TT HRP20171611T1 (hr) | 2013-06-26 | 2014-06-24 | N-(4-hidroksi-4-metil-cikloheksil)-4-fenil-benzensulfonamidi i n-(4-hidroksi-4-metil-cikloheksil)-4-(2-piridil)-benzensulfonamidi i njihova terapeutska primjena |
| MX2015016914A MX374328B (es) | 2013-06-26 | 2014-06-24 | N-(4-hidroxi-4-metil-ciclohexil)-4-fenil-bencensulfonamidas y n-(4-hidroxi-4-metil-ciclohexil)-4-(2-piridil)bencensulfonamidas y su uso terapéutico. |
| MEP-2017-208A ME02834B (me) | 2013-06-26 | 2014-06-24 | N-(4-hidroksi-4-metil-cikloheksil)-4-fenil-benzensulfonamid i n-(4-hidroksi-4-metilcikloheksil)- 4-(2-piridil)benzensulfonamid i nihova terapijska upotreba |
| CN201480047140.2A CN105492426B (zh) | 2013-06-26 | 2014-06-24 | N‑(4‑羟基‑4‑甲基‑环己基)‑4‑苯基‑苯磺酰胺和n‑(4‑羟基‑4‑甲基‑环己基)‑4‑(2‑吡啶基)苯磺酰胺和其治疗性用途 |
| JP2016522860A JP6360555B2 (ja) | 2013-06-26 | 2014-06-24 | N−(4−ヒドロキシ−4−メチル−シクロヘキシル)−4−フェニル−ベンゼンスルホンアミド及びn−(4−ヒドロキシ−4−メチル−シクロヘキシル)−4−(2−ピリジル)ベンゼンスルホンアミド、並びにそれらの治療的使用 |
| SI201430364T SI3013799T1 (sl) | 2013-06-26 | 2014-06-24 | N-(4-hidroksi-4-metil-cikloheksil)-4-fenil-benzensulfonamidi in N-(4-hidroksi-4-metil-cikloheksil)-4-(2-piridil)benzensulfonamidi in njihova terapevtska uporaba |
| KR1020167002015A KR102151299B1 (ko) | 2013-06-26 | 2014-06-24 | N-(4-하이드록시-4-메틸-사이클로헥실)-4-페닐-벤젠설폰아미드 및 n-(4-하이드록시-4-메틸-사이클로헥실)-4-(2-피리딜)벤젠설폰아미드 및 이들의 치료 용도 |
| LTEP14735642.2T LT3013799T (lt) | 2013-06-26 | 2014-06-24 | N-(4-hidroksi-4-metil-cikloheksil)-4-fenil-benzensulfonamidai ir n-(4-hidroksi-4-metil-cikloheksil)-4-(2-piridil)benzensulfonamidai bei jų terapinis panaudojimas |
| HK16105875.1A HK1218115B (en) | 2013-06-26 | 2014-06-24 | N-(4-hydroxy-4-methyl-cyclohexyl)-4-phenyl-benzenesulfonamides and n-(4-hydroxy-4-methyl-cyclohexyl)-4-(2-pyridyl)benzenesulfonamides and their therapeutic use |
| RS20170876A RS56256B1 (sr) | 2013-06-26 | 2014-06-24 | N-(4-hidroksi-4-metil-cikloheksil)-4-fenil-benzensulfonamid i n-(4-hidroksi-4-metil-cikloheksil)-4-(2-piridil)benzensulfonamid i njihova terapijska upotreba |
| SM20170503T SMT201700503T1 (it) | 2013-06-26 | 2014-06-24 | N-(4-idrossi-4-metil-cicloesil)-4-fenil-benzensolfonammidi e n-(4-idrossi-4-metil-cicloesil)-4- (2-piridil)benzensolfonammidi e loro uso terapeutico |
| PT147356422T PT3013799T (pt) | 2013-06-26 | 2014-06-24 | N-(4-hidroxi-4-metil-ciclohexil)-4-fenil-benzenossulfonamidas e n-(4-hidroxi-4-metil-ciclohexil)-4-(2-piridil)benzenossulfonamidas e a sua utilização terapêutica |
| ES14735642.2T ES2641758T3 (es) | 2013-06-26 | 2014-06-24 | N-(4-hidroxi-4-metil-ciclohexil)-4-fenil-bencenosulfonamidas y N-(4-hidroxi-4-metil-ciclohexil)-4-(2-piridil)bencenosulfonamidas y su uso terapéutico |
| EP14735642.2A EP3013799B1 (en) | 2013-06-26 | 2014-06-24 | N-(4-hydroxy-4-methyl-cyclohexyl)-4-phenyl-benzenesulfonamides and n-(4-hydroxy-4-methyl-cyclohexyl)-4-(2-pyridyl)benzenesulfonamides and their therapeutic use |
| EA201592308A EA028077B1 (ru) | 2013-06-26 | 2014-06-24 | N-(4-гидрокси-4-метилциклогексил)-4-фенилбензолсульфонамиды и n-(4-гидрокси-4-метилциклогексил)-4-(2-пиридил)бензолсульфонамиды и их терапевтическое применение |
| NZ715192A NZ715192A (en) | 2013-06-26 | 2014-06-24 | N-(4-hydroxy-4-methyl-cyclohexyl)-4-phenyl-benzenesulfonamides and n-(4-hydroxy-4-methyl-cyclohexyl)-4-(2-pyridyl)benzenesulfonamides and their therapeutic use |
| AU2014300745A AU2014300745B2 (en) | 2013-06-26 | 2014-06-24 | N-(4-hydroxy-4-methyl-cyclohexyl)-4-phenyl-benzenesulfonamides and N-(4-hydroxy-4-methyl-cyclohexyl)-4-(2-pyridyl)benzenesulfonamides and their therapeutic use |
| SG11201510646SA SG11201510646SA (en) | 2013-06-26 | 2014-06-24 | N-(4-hydroxy-4-methyl-cyclohexyl)-4-phenyl-benzenesulfonamides and n-(4-hydroxy-4-methyl-cyclohexyl)-4-(2-pyridyl)benzenesulfonamides and their therapeutic use |
| HUE14735642A HUE034983T2 (en) | 2013-06-26 | 2014-06-24 | N-(4-hydroxy-4-methyl-cyclohexyl)-4-phenyl-benzenesulfonamides and n-(4-hydroxy-4-methyl-cyclohexyl)-4-(2-pyridyl)benzenesulfonamides and their therapeutic use |
| US14/899,422 US9624167B2 (en) | 2013-06-26 | 2014-06-24 | N-(4-hydroxy-4-methyl-cyclohexyl)-4-phenyl-benzenesulfonamides and N-(4-hydroxy-4-methyl-cyclohexyl)-4-(2-pyridyl)benzenesulfonamides and their therapeutic use |
| PCT/GB2014/051921 WO2014207445A1 (en) | 2013-06-26 | 2014-06-24 | N-(4-hydroxy-4-methyl-cyclohexyl)-4-phenyl-benzenesulfonamides and n-(4-hydroxy-4-methyl-cyclohexyl)-4-(2-pyridyl)benzenesulfonamides and their therapeutic use |
| BR112015031527-5A BR112015031527B1 (pt) | 2013-06-26 | 2014-06-24 | N-(4-hidróxi-4-metil-ciclo-hexil)-4-fenil- benzenossulfonamidas e n-(4- hidróxi-4-metil-ciclo-hexil)-4-(2-piridil) benze-nossulfonamidas, seus usos, composição farmacêutica e seu método de preparação |
| PL14735642T PL3013799T3 (pl) | 2013-06-26 | 2014-06-24 | N-(4-hydroksy-4-metylocykloheksylo)-4-fenylobenzenosulfonamidy i N-(4-hydroksy-4- metylocykloheksylo)-4-(2-pirydylo)benzenosulfonamidy i ich zastosowanie terapeutyczne |
| IL243103A IL243103B (en) | 2013-06-26 | 2015-12-14 | N-(4-hydroxy-4-methyl-cyclohexyl)-4-phenyl-benzenesulfonamides and n-(4-hydroxy-4-methyl-cyclohexyl)-4-(2-pyridyl)benzenesulfonamides and their medical use |
| ZA2016/00202A ZA201600202B (en) | 2013-06-26 | 2016-01-11 | N-(4-hydroxy-4-methyl-cyclohexyl)-4-phenyl-benzenesulfonamides and n-(4-hydroxy-4-methyl-cyclohexyl)-4-(2-pyridyl)benzenesulfonamides and their therapeutic use |
| US15/484,256 US9796670B2 (en) | 2013-06-26 | 2017-04-11 | N-(4-hydroxy-4-methyl-cyclohexyl)-4-phenyl-benzenesulfonamides and N-(4-hydroxy-4-methyl-cyclohexyl)-4-(2-pyridyl)benzenesulfonamides and their therapeutic use |
| CY20171101060T CY1119438T1 (el) | 2013-06-26 | 2017-10-11 | Ν-(4-υδροξυ-4-μεθυλ-κυκλοεξυλ)-4-φαινυλ-βενζολοσουλφοναμιδια και ν-(4-υδροξυ-4-μεθυλ-κυκλοεξυλ)-4-(2-πυριδυλ)βενζολοσουλφοναμιδια και η θεραπευτικη τους χρηση |
| US15/786,021 US10029979B2 (en) | 2013-06-26 | 2017-10-17 | N-(4-hydroxy-4-methyl-cyclohexyl)-4-phenyl-benzenesulfonamides and N-(4-hydroxy-4-methyl-cyclohexyl)-4-(2-pyridyl)benzenesulfonamides and their therapeutic use |
| US16/037,048 US10233147B2 (en) | 2013-06-26 | 2018-07-17 | N-(4-hydroxy-4-methyl-cyclohexyl)-4-phenyl-benzenesulfonamides and N-(4-hydroxy-4-methyl-cyclohexyl)-4-(2-pyridyl)benzenesulfonamides and their therapeutic use |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1311361.8A GB201311361D0 (en) | 2013-06-26 | 2013-06-26 | Compounds and their therapeutic use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB201311361D0 true GB201311361D0 (en) | 2013-08-14 |
Family
ID=48998987
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GBGB1311361.8A Ceased GB201311361D0 (en) | 2013-06-26 | 2013-06-26 | Compounds and their therapeutic use |
Country Status (28)
| Country | Link |
|---|---|
| US (4) | US9624167B2 (enExample) |
| EP (1) | EP3013799B1 (enExample) |
| JP (1) | JP6360555B2 (enExample) |
| KR (1) | KR102151299B1 (enExample) |
| CN (1) | CN105492426B (enExample) |
| AU (1) | AU2014300745B2 (enExample) |
| BR (1) | BR112015031527B1 (enExample) |
| CA (1) | CA2915075C (enExample) |
| CY (1) | CY1119438T1 (enExample) |
| DK (1) | DK3013799T3 (enExample) |
| EA (1) | EA028077B1 (enExample) |
| ES (1) | ES2641758T3 (enExample) |
| GB (1) | GB201311361D0 (enExample) |
| HR (1) | HRP20171611T1 (enExample) |
| HU (1) | HUE034983T2 (enExample) |
| IL (1) | IL243103B (enExample) |
| LT (1) | LT3013799T (enExample) |
| ME (1) | ME02834B (enExample) |
| MX (1) | MX374328B (enExample) |
| NZ (1) | NZ715192A (enExample) |
| PL (1) | PL3013799T3 (enExample) |
| PT (1) | PT3013799T (enExample) |
| RS (1) | RS56256B1 (enExample) |
| SG (1) | SG11201510646SA (enExample) |
| SI (1) | SI3013799T1 (enExample) |
| SM (1) | SMT201700503T1 (enExample) |
| WO (1) | WO2014207445A1 (enExample) |
| ZA (1) | ZA201600202B (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0817207D0 (en) | 2008-09-19 | 2008-10-29 | Pimco 2664 Ltd | therapeutic apsac compounds and their use |
| GB201311361D0 (en) | 2013-06-26 | 2013-08-14 | Pimco 2664 Ltd | Compounds and their therapeutic use |
| AU2015367528B2 (en) * | 2014-12-17 | 2020-05-14 | Pimco 2664 Limited | N-(4-hydroxy-4-methyl-cyclohexyl)-4-phenyl-benzenesulfonamide and N-(4-hydroxy-4-methyl-cyclohexyl)-4-(2-pyridyl)-benzenesulfonamide compounds and their therapeutic use |
| GB201813312D0 (en) * | 2018-08-15 | 2018-09-26 | Modern Biosciences Ltd | Compounds and their therapeutic use |
| GB201905520D0 (en) * | 2019-04-18 | 2019-06-05 | Modern Biosciences Ltd | Compounds and their therapeutic use |
| EP4431090A1 (en) | 2023-03-15 | 2024-09-18 | Istesso 1 Limited | Solfonamides acting as mitochondrial complex i modulator compounds |
| GB202308547D0 (en) | 2023-06-08 | 2023-07-26 | Istesso 2 Ltd | Tnf inhibitor combination therapies |
| GB202309515D0 (en) | 2023-06-23 | 2023-08-09 | Istesso 2 Ltd | JAK inhibitor and IL-6 inhibitor combination therapies |
| GB202315822D0 (en) | 2023-10-16 | 2023-11-29 | Istesso 3 Ltd | Anti-fibrotic combination therapeutics |
| GB202317050D0 (en) | 2023-11-07 | 2023-12-20 | Istesso 2 Ltd | Disease modifying anti-rheumatic drug combination therapies |
| EP4647071A1 (en) | 2024-05-10 | 2025-11-12 | Istesso Therapeutics Limited | Mitochondrial complex i modulator for use in the treatment of arthritis |
Family Cites Families (58)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB597810A (en) | 1943-04-12 | 1948-02-04 | Gen Printing Ink Corp | Improvements in or relating to derivatives of diphenyl |
| DE1046220B (de) | 1956-04-21 | 1958-12-11 | Bayer Ag | Verfahren zur Herstellung von Monoazofarbstoffen und deren Metallkomplexverbindungen |
| US4119784A (en) | 1977-07-01 | 1978-10-10 | American Cyanamid Company | Anionic substituted sulfonamido biphenyls |
| DE3000519A1 (de) | 1979-02-01 | 1980-08-14 | Byk Gulden Lomberg Chem Fab | Sulfonamido-alkansaeuren, ihre verwendung und herstellung sowie sie enthaltende arzneimittel |
| DE3535167A1 (de) | 1985-10-02 | 1987-04-09 | Boehringer Mannheim Gmbh | Neue sulfonyl-phenyl(alkyl)amine, verfahren zu ihrer herstellung sowie arzneimittel |
| IL118325A0 (en) | 1995-05-25 | 1996-10-31 | Pont Merck And Pharmaceutical | Integrin receptor antagonists and pharmaceutical compositions containing them |
| AP9801222A0 (en) | 1995-10-30 | 1998-06-30 | Smithkline Beecham Corp | Proatease inhibitors. |
| US5760028A (en) | 1995-12-22 | 1998-06-02 | The Dupont Merck Pharmaceutical Company | Integrin receptor antagonists |
| WO1997033887A1 (en) | 1996-03-15 | 1997-09-18 | Du Pont Pharmaceuticals Company | Spirocycle integrin inhibitors |
| PL331338A1 (en) | 1996-07-22 | 1999-07-05 | Monsanto Co | Thiosulphonamidic metaloprotease inhibitors |
| PT938471E (pt) | 1996-10-16 | 2002-05-31 | American Cyanamid Co | A preparacao e uso de acidos ortosulfonamidoarilhidroxamicos como inibidores de metaloproteinases de matriz e "tace" |
| DK0944619T3 (da) | 1996-11-27 | 2007-02-05 | Bristol Myers Squibb Pharma Co | Hidtil ukendte integrinreceptorantagonister |
| AU6780398A (en) | 1997-03-28 | 1998-10-22 | Du Pont Merck Pharmaceutical Company, The | Heterocyclic integrin inhibitor prodrugs |
| WO1998050342A1 (en) | 1997-05-08 | 1998-11-12 | Smithkline Beecham Corporation | Protease inhibitors |
| DE19719621A1 (de) | 1997-05-09 | 1998-11-12 | Hoechst Ag | Sulfonylaminocarbonsäuren |
| PT877019E (pt) | 1997-05-09 | 2002-05-31 | Hoechst Ag | Acidos diaminocarboxilicos substituidos |
| US6291425B1 (en) | 1999-09-01 | 2001-09-18 | Guilford Pharmaceuticals Inc. | Compounds, methods and pharmaceutical compositions for treating cellular damage, such as neural or cardiovascular tissue damage |
| UA63990C2 (uk) | 1998-01-23 | 2004-02-16 | Авентіс Фарма Дойчланд Гмбх | Сульфонамідні похідні, спосіб їх одержання та фармацевтична композиція на їх основі |
| EP1918278A1 (en) | 1998-02-04 | 2008-05-07 | Novartis AG | Sulfonylamino derivatives which inhibit matrix-degrading metalloproteinases |
| JPH11246527A (ja) | 1998-03-02 | 1999-09-14 | Shionogi & Co Ltd | Mmp−8阻害剤 |
| DE19815547C1 (de) | 1998-04-07 | 1999-12-02 | Joachim Schmidt | Haftmittel für Zahnprothesen |
| EP0960882A1 (en) | 1998-05-19 | 1999-12-01 | Hoechst Marion Roussel Deutschland GmbH | Thienyl substituted acylguanidines as inhibitors of bone resorption and vitronectin receptor antagonists |
| MXPA02009309A (es) | 2000-03-21 | 2003-03-12 | Procter & Gamble | Inhibidores de las metaloproteasas n-sustituidas que contienen cadenas laterales carboxiclicas. |
| AU2001264595A1 (en) | 2000-05-19 | 2001-12-03 | Guilford Pharmaceuticals Inc. | Sulfonamide and carbamide derivatives of 6(5h)phenanthridinones and their uses |
| AU2002228316A1 (en) | 2001-01-29 | 2002-08-12 | Insight Strategy And Marketing Ltd | Carbazole derivatives and their uses as heparanase inhibitors |
| US20050119305A1 (en) | 2001-03-21 | 2005-06-02 | Masao Naka | Il-6 production inhibitors |
| JP2004535390A (ja) | 2001-05-07 | 2004-11-25 | スミスクライン・ビーチャム・コーポレイション | スルホンアミド |
| PL368129A1 (en) | 2001-08-09 | 2005-03-21 | Ono Pharmaceutical Co, Ltd. | Carboxylic acid derivative compounds and drugs comprising these compounds as the active ingredient |
| GB0126157D0 (en) | 2001-10-31 | 2002-01-02 | Univ Aberdeen | Therapeutic compounds |
| EP1491190A4 (en) | 2002-03-27 | 2006-01-04 | Shionogi & Co | DECOMPOSITION INHIBITOR FOR CARTRIDGE EXTRACELLULAR MATRIX |
| JP4881558B2 (ja) | 2002-09-04 | 2012-02-22 | シェーリング コーポレイション | サイクリン依存性キナーゼインヒビターとしてのピラゾロピリミジン |
| DE10251170A1 (de) | 2002-10-31 | 2004-05-13 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue Beta-Agonisten, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel |
| WO2004073619A2 (en) | 2003-02-14 | 2004-09-02 | Smithkline Beecham Corporation | Ccr8 antagonists |
| DK1638544T3 (da) | 2003-05-07 | 2008-03-31 | Univ Aberdeen | Ketoner og reducerede ketoner som terapeutiske midler til behandling af knogletilstande |
| WO2004106290A1 (ja) | 2003-05-14 | 2004-12-09 | Kissei Pharmaceutical Co., Ltd. | アミノアルコール誘導体、それを含有する医薬組成物およびそれらの用途 |
| AR046330A1 (es) | 2003-09-09 | 2005-12-07 | Japan Tobacco Inc | Inhibidor de dipeptidilpeptidasa iv |
| GB0324792D0 (en) | 2003-10-23 | 2003-11-26 | Sterix Ltd | Compound |
| EP1696915A1 (en) | 2003-12-19 | 2006-09-06 | Pfizer, Inc. | Benzenesulfonylamino-pyridin-2-yl derivatives and related compounds as inhibitors of 11-beta-hydroxysteroid dehydrogenase type 1 (11-beta-hsd-1) for the treatment of diabetes and obesity |
| EP1723132A1 (en) | 2004-02-12 | 2006-11-22 | Asterand Uk Limited | Ep2 receptor agonists |
| GB0405193D0 (en) | 2004-03-08 | 2004-04-21 | Medical Res Council | Compounds |
| US20080255240A1 (en) | 2004-05-05 | 2008-10-16 | Novo Nordisk A/S | Sulfonamide Derivatives |
| GB0412553D0 (en) | 2004-06-04 | 2004-07-07 | Univ Aberdeen | Therapeutic agents for the treatment of bone conditions |
| US7470722B2 (en) | 2004-06-10 | 2008-12-30 | Kalypsys, Inc. | Multicyclic sulfonamide compounds as inhibitors of histone deacetylase for the treatment of disease |
| MX2007004862A (es) | 2004-10-29 | 2007-05-09 | Astrazeneca Ab | Nuevos derivados de sulfonamida como moduladores del receptor de glucocorticoides para el tratamiento de enfermedades inflamatorias. |
| EP1659113A1 (en) | 2004-11-08 | 2006-05-24 | Evotec AG | Inhibitors of 11beta-hydroxy steroid dehydrogenase type 1 (11beta-HSD1) |
| EA200702498A1 (ru) | 2005-06-16 | 2008-06-30 | Пфайзер Инк. | N-(пиридин-2-ил)сульфонамидные производные |
| WO2007008541A2 (en) | 2005-07-08 | 2007-01-18 | Kalypsys, Inc. | Cellular cholesterol absorption modifiers |
| TW200720261A (en) | 2005-08-31 | 2007-06-01 | Sankyo Co | Phenylene derivatives |
| DK2774925T3 (en) | 2005-11-08 | 2017-02-27 | Vertex Pharma | Heterocyclic modulators of ATP binding cassette transporters |
| AU2006337137B2 (en) | 2005-12-29 | 2012-06-14 | Tersera Therapeutics Llc | Multicyclic amino acid derivatives and methods of their use |
| US7560597B2 (en) | 2007-03-08 | 2009-07-14 | The University Court Of The University Of Aberdeen | 2′,4′-dichloro-biphenyl-4-yl-hydroxy-ketones and related compounds and their use as therapeutic agents |
| GB0705400D0 (en) | 2007-03-21 | 2007-05-02 | Univ Aberdeen | Therapeutic compounds andm their use |
| US8283368B2 (en) | 2008-08-29 | 2012-10-09 | The Regents Of The University Of Michigan | Selective ligands for the dopamine 3 (D3) receptor and methods of using the same |
| TWI453207B (zh) | 2008-09-08 | 2014-09-21 | Signal Pharm Llc | 胺基三唑并吡啶,其組合物及使用其之治療方法 |
| GB0817208D0 (en) | 2008-09-19 | 2008-10-29 | Pimco 2664 Ltd | Therapeutic apsap compounds and their use |
| GB0817207D0 (en) * | 2008-09-19 | 2008-10-29 | Pimco 2664 Ltd | therapeutic apsac compounds and their use |
| GB201311361D0 (en) | 2013-06-26 | 2013-08-14 | Pimco 2664 Ltd | Compounds and their therapeutic use |
| AU2015367528B2 (en) | 2014-12-17 | 2020-05-14 | Pimco 2664 Limited | N-(4-hydroxy-4-methyl-cyclohexyl)-4-phenyl-benzenesulfonamide and N-(4-hydroxy-4-methyl-cyclohexyl)-4-(2-pyridyl)-benzenesulfonamide compounds and their therapeutic use |
-
2013
- 2013-06-26 GB GBGB1311361.8A patent/GB201311361D0/en not_active Ceased
-
2014
- 2014-06-24 AU AU2014300745A patent/AU2014300745B2/en active Active
- 2014-06-24 LT LTEP14735642.2T patent/LT3013799T/lt unknown
- 2014-06-24 ME MEP-2017-208A patent/ME02834B/me unknown
- 2014-06-24 EP EP14735642.2A patent/EP3013799B1/en active Active
- 2014-06-24 KR KR1020167002015A patent/KR102151299B1/ko active Active
- 2014-06-24 HU HUE14735642A patent/HUE034983T2/en unknown
- 2014-06-24 CN CN201480047140.2A patent/CN105492426B/zh active Active
- 2014-06-24 EA EA201592308A patent/EA028077B1/ru unknown
- 2014-06-24 NZ NZ715192A patent/NZ715192A/en unknown
- 2014-06-24 JP JP2016522860A patent/JP6360555B2/ja active Active
- 2014-06-24 SG SG11201510646SA patent/SG11201510646SA/en unknown
- 2014-06-24 WO PCT/GB2014/051921 patent/WO2014207445A1/en not_active Ceased
- 2014-06-24 CA CA2915075A patent/CA2915075C/en active Active
- 2014-06-24 SI SI201430364T patent/SI3013799T1/sl unknown
- 2014-06-24 PT PT147356422T patent/PT3013799T/pt unknown
- 2014-06-24 BR BR112015031527-5A patent/BR112015031527B1/pt active IP Right Grant
- 2014-06-24 SM SM20170503T patent/SMT201700503T1/it unknown
- 2014-06-24 DK DK14735642.2T patent/DK3013799T3/en active
- 2014-06-24 RS RS20170876A patent/RS56256B1/sr unknown
- 2014-06-24 HR HRP20171611TT patent/HRP20171611T1/hr unknown
- 2014-06-24 PL PL14735642T patent/PL3013799T3/pl unknown
- 2014-06-24 MX MX2015016914A patent/MX374328B/es active IP Right Grant
- 2014-06-24 US US14/899,422 patent/US9624167B2/en active Active
- 2014-06-24 ES ES14735642.2T patent/ES2641758T3/es active Active
-
2015
- 2015-12-14 IL IL243103A patent/IL243103B/en active IP Right Grant
-
2016
- 2016-01-11 ZA ZA2016/00202A patent/ZA201600202B/en unknown
-
2017
- 2017-04-11 US US15/484,256 patent/US9796670B2/en active Active
- 2017-10-11 CY CY20171101060T patent/CY1119438T1/el unknown
- 2017-10-17 US US15/786,021 patent/US10029979B2/en active Active
-
2018
- 2018-07-17 US US16/037,048 patent/US10233147B2/en active Active
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GB201320729D0 (en) | Therapeutic compounds and their use | |
| ZA201506487B (en) | Therapeutic compounds and compositions | |
| GB201321743D0 (en) | Therapeutic agents | |
| GB201321746D0 (en) | Therapeutic agents | |
| GB201321738D0 (en) | Therapeutic Agents | |
| GB201321736D0 (en) | Therapeutic agents | |
| GB201321729D0 (en) | Therapeutic agents | |
| GB201321728D0 (en) | Therapeutic agents | |
| GB201321733D0 (en) | Therapeutic agents | |
| GB201321730D0 (en) | Therapeutic agents | |
| GB201321739D0 (en) | Therapeutic agents | |
| GB201321741D0 (en) | Therapeutic agents | |
| GB201321740D0 (en) | Therapeutic agents | |
| GB201321732D0 (en) | Therapeutic agents | |
| GB201321734D0 (en) | Therapeutic Agents | |
| GB201321744D0 (en) | Therapeutic agents | |
| GB201321737D0 (en) | Therapeutic Agents | |
| GB201311361D0 (en) | Compounds and their therapeutic use | |
| GB201321748D0 (en) | Therapeutic agents | |
| GB201321742D0 (en) | Therapeutic agents | |
| GB201321735D0 (en) | Therapeutic Agents | |
| GB201321745D0 (en) | Therapeutic agents | |
| GB201308440D0 (en) | Therapeutic | |
| GB201321731D0 (en) | Therapeutic agents | |
| ZA201607581B (en) | Dosage forms and therapeutic uses l-4lchlorokynurenine |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AT | Applications terminated before publication under section 16(1) | ||
| AT | Applications terminated before publication under section 16(1) |