GB201002730D0 - Product - Google Patents

Product

Info

Publication number
GB201002730D0
GB201002730D0 GBGB1002730.8A GB201002730A GB201002730D0 GB 201002730 D0 GB201002730 D0 GB 201002730D0 GB 201002730 A GB201002730 A GB 201002730A GB 201002730 D0 GB201002730 D0 GB 201002730D0
Authority
GB
United Kingdom
Prior art keywords
product
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB1002730.8A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universitetet i Oslo
Original Assignee
Universitetet i Oslo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universitetet i Oslo filed Critical Universitetet i Oslo
Priority to GBGB1002730.8A priority Critical patent/GB201002730D0/en
Publication of GB201002730D0 publication Critical patent/GB201002730D0/en
Priority to AU2011217027A priority patent/AU2011217027B2/en
Priority to RS20160323A priority patent/RS54744B1/sr
Priority to RU2012138302/10A priority patent/RU2604813C2/ru
Priority to PL11730044T priority patent/PL2536746T3/pl
Priority to US13/579,887 priority patent/US8828379B2/en
Priority to HUE11730044A priority patent/HUE027952T2/en
Priority to ES11730044T priority patent/ES2572388T3/es
Priority to SI201130815A priority patent/SI2536746T1/sl
Priority to HRP20160475TT priority patent/HRP20160475T1/hr
Priority to PCT/GB2011/050325 priority patent/WO2011101681A2/en
Priority to JP2012553409A priority patent/JP5537675B2/ja
Priority to KR1020127024287A priority patent/KR101647176B1/ko
Priority to CA2789492A priority patent/CA2789492C/en
Priority to EP11730044.2A priority patent/EP2536746B1/en
Priority to CN201180011237.4A priority patent/CN102947330B/zh
Priority to DK11730044.2T priority patent/DK2536746T3/en
Priority to US14/331,014 priority patent/US9056920B2/en
Priority to CY20161100397T priority patent/CY1117697T1/el
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70539—MHC-molecules, e.g. HLA-molecules
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
    • G01N33/6869—Interleukin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
GBGB1002730.8A 2010-02-18 2010-02-18 Product Ceased GB201002730D0 (en)

Priority Applications (19)

Application Number Priority Date Filing Date Title
GBGB1002730.8A GB201002730D0 (en) 2010-02-18 2010-02-18 Product
DK11730044.2T DK2536746T3 (en) 2010-02-18 2011-02-18 Disulphide-bond stabilized functional soluble MHC class II heterodimeric
SI201130815A SI2536746T1 (sl) 2010-02-18 2011-02-18 Z disulfidno vezjo-stabilizirani funkcionalni topni heterodimeri mhc razreda ii
PCT/GB2011/050325 WO2011101681A2 (en) 2010-02-18 2011-02-18 Disulphide bond-stabilized functional soluble mhc class ii heterodimers
RU2012138302/10A RU2604813C2 (ru) 2010-02-18 2011-02-18 Функциональные растворимые гетеродимеры мнс ii класса со стабилизирующей дисульфидной связью
PL11730044T PL2536746T3 (pl) 2010-02-18 2011-02-18 Stabilizowane wiązaniem disulfidowym funkcjonalne rozpuszczalne heterodimery mhc klasy ii
US13/579,887 US8828379B2 (en) 2010-02-18 2011-02-18 Disulphide bond-stabilized functional soluble MHC class II heterodimers
HUE11730044A HUE027952T2 (en) 2010-02-18 2011-02-18 Disulfide bonded, functional, soluble, MCH class II heterodimers
ES11730044T ES2572388T3 (es) 2010-02-18 2011-02-18 Heterodímeros del MHC de clase II solubles funcionales estabilizados por enlaces disulfuro
AU2011217027A AU2011217027B2 (en) 2010-02-18 2011-02-18 Disulphide bond-stabilized functional soluble MHC class II heterodimers
HRP20160475TT HRP20160475T1 (hr) 2010-02-18 2011-02-18 Disulfidnom vezom stabilizirani funkcionalni topivi heterodimeri mhc klase ii
RS20160323A RS54744B1 (sr) 2010-02-18 2011-02-18 Rastvorljivi funkcionalni heterodimeri mhc klase ii stabilizovani disulfidnom vezom
JP2012553409A JP5537675B2 (ja) 2010-02-18 2011-02-18 ジスルフィド結合により安定化された機能的可溶性ｍｈｃクラスｉｉヘテロ二量体
KR1020127024287A KR101647176B1 (ko) 2010-02-18 2011-02-18 디설파이드 결합으로 안정화된 기능성 가용성 ｍｈｃ클래스 ⅱ 헤테로다이머류
CA2789492A CA2789492C (en) 2010-02-18 2011-02-18 Disulphide bond-stabilized functional soluble mhc class ii heterodimers
EP11730044.2A EP2536746B1 (en) 2010-02-18 2011-02-18 Disulphide bond-stabilized functional soluble mhc class ii heterodimers
CN201180011237.4A CN102947330B (zh) 2010-02-18 2011-02-18 二硫键稳定的功能性可溶mhc ii类异二聚体
US14/331,014 US9056920B2 (en) 2010-02-18 2014-07-14 Disulphide bond-stabilized functional soluble MHC class II heterodimers
CY20161100397T CY1117697T1 (el) 2010-02-18 2016-05-11 Σταθεροποιημενα απο δεσμους δισουλφιδιων λειτουργικα ευδιαλυτα ετεροδιμερη toy mhc ταξης ii

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1002730.8A GB201002730D0 (en) 2010-02-18 2010-02-18 Product

Publications (1)

Publication Number Publication Date
GB201002730D0 true GB201002730D0 (en) 2010-04-07

Family

ID=42113985

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB1002730.8A Ceased GB201002730D0 (en) 2010-02-18 2010-02-18 Product

Country Status (18)

Country Link
US (2) US8828379B2 (enExample)
EP (1) EP2536746B1 (enExample)
JP (1) JP5537675B2 (enExample)
KR (1) KR101647176B1 (enExample)
CN (1) CN102947330B (enExample)
AU (1) AU2011217027B2 (enExample)
CA (1) CA2789492C (enExample)
CY (1) CY1117697T1 (enExample)
DK (1) DK2536746T3 (enExample)
ES (1) ES2572388T3 (enExample)
GB (1) GB201002730D0 (enExample)
HR (1) HRP20160475T1 (enExample)
HU (1) HUE027952T2 (enExample)
PL (1) PL2536746T3 (enExample)
RS (1) RS54744B1 (enExample)
RU (1) RU2604813C2 (enExample)
SI (1) SI2536746T1 (enExample)
WO (1) WO2011101681A2 (enExample)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10787701B2 (en) 2010-04-05 2020-09-29 Prognosys Biosciences, Inc. Spatially encoded biological assays
RU2746407C1 (ru) 2012-02-23 2021-04-13 Стейдж Селл Терапеутикс Гмбх Хроматографическое выделение клеток и других сложных биологических материалов
USRE50065E1 (en) 2012-10-17 2024-07-30 10X Genomics Sweden Ab Methods and product for optimising localised or spatial detection of gene expression in a tissue sample
GB201309469D0 (en) 2013-05-28 2013-07-10 Imcyse Sa Detection of CD4+ T lymphocytes
RU2732148C2 (ru) * 2014-07-09 2020-09-11 Люпин Лимитед Двухцистронная бактериальная система экспрессии
US11059880B2 (en) 2015-06-30 2021-07-13 Arizona Board Of Regents On Behalf Of The University Of Arizona Redirected cells with MHC chimeric receptors and methods of use in immunotherapy
MA45489A (fr) 2015-10-22 2018-08-29 Juno Therapeutics Gmbh Procédés de culture de cellules, kits et appareil associés
MA45426A (fr) 2015-10-22 2019-05-01 Juno Therapeutics Gmbh Procédés, kits, agents et appareils de transduction
US10294454B2 (en) 2016-08-24 2019-05-21 General Electric Company Methods and kits for cell activation
AU2017357865B2 (en) * 2016-11-09 2024-10-31 Uti Limited Partnership Recombinant pMHC class II molecules
CN111032850B (zh) 2017-04-27 2024-08-13 朱诺治疗学有限公司 寡聚粒子试剂及其使用方法
DE102018122546B3 (de) 2018-09-14 2019-12-05 Immatics Biotechnologies Gmbh Verfahren zum Hochdurchsatz-Peptid-MHC-Affinitätsscreening für TCR-Liganden
US20230147726A1 (en) * 2018-09-28 2023-05-11 Danmarks Tekniske Universitet High throughput epitope identification and t cell receptor specificity determination using loadable detection molecules
TWI852977B (zh) 2019-01-10 2024-08-21 美商健生生物科技公司 前列腺新抗原及其用途
EP3719033A1 (en) * 2019-04-02 2020-10-07 imusyn GmbH & Co. KG Stabilized mhc i
WO2021035049A1 (en) * 2019-08-21 2021-02-25 Uti Limited Partnership Improved recombinant pmhc molecules
WO2021050792A2 (en) * 2019-09-13 2021-03-18 The Regents Of The University Of California Systems and methods for the preparation of peptide-mhc-i complexes with native glycan modifications
KR20220110233A (ko) * 2019-12-02 2022-08-05 리제너론 파마슈티칼스 인코포레이티드 펩티드-mhc ii 단백질 작제물 및 그의 용도
TW202144388A (zh) 2020-02-14 2021-12-01 美商健生生物科技公司 在卵巢癌中表現之新抗原及其用途
TW202144389A (zh) 2020-02-14 2021-12-01 美商健生生物科技公司 在多發性骨髓瘤中表現之新抗原及其用途
DE102020109447A1 (de) 2020-04-03 2021-10-07 Jacobs University Bremen Ggmbh Synthetisches mhc-klasse-ii-protein
WO2022009052A2 (en) 2020-07-06 2022-01-13 Janssen Biotech, Inc. Prostate neoantigens and their uses
CN118813436A (zh) * 2023-07-24 2024-10-22 佳吾益(北京)科技有限公司 展示单mhc等位基因功能蛋白的工程化细胞
CN119220425A (zh) * 2023-07-28 2024-12-31 佳吾益(北京)科技有限公司 发现mhc新抗原肽表位的工程化细胞
WO2025137580A1 (en) * 2023-12-22 2025-06-26 Antiger Therapeutics, Inc. Class ii hla with inter-chain disulfide bond

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990010457A1 (en) 1989-03-14 1990-09-20 New York University Method of treating hiv infections using immunotoxins
AU730457B2 (en) * 1996-08-16 2001-03-08 President And Fellows Of Harvard College Soluble monovalent and multivalent MHC class II fusion proteins, and uses therefor
CA2302779C (en) * 1997-09-16 2010-02-02 Oregon Health Sciences University Recombinant mhc molecules useful for manipulation of antigen-specific t-cells
WO1999060120A2 (en) * 1998-05-19 1999-11-25 Avidex Limited Soluble t cell receptor
RU2303264C2 (ru) * 2001-02-19 2007-07-20 Мерк Патент Гмбх Способ идентификации эпитопов т-клеток и его применение для получения молекул со сниженной иммуногенностью
GB2392158B (en) * 2002-08-21 2005-02-16 Proimmune Ltd Chimeric MHC protein and oligomer thereof
ES2559409T3 (es) * 2003-09-05 2016-02-12 Oregon Health & Science University Moléculas de MHC recombinantes monoméricas útiles para la manipulación de células T específicas de antígenos
CA2638892A1 (en) * 2005-03-18 2006-09-28 Oregon Health & Science University Recombinant mhc molecules useful for manipulation of antigen-specific t cells
ES2657504T3 (es) 2006-08-11 2018-03-05 Life Sciences Research Partners Vzw Péptidos inmunogénicos y su uso en trastornos inmunitarios
EP2097789B1 (en) * 2006-12-01 2012-08-01 Carl Zeiss SMT GmbH Optical system with an exchangeable, manipulable correction arrangement for reducing image aberrations
US8735330B2 (en) 2007-08-20 2014-05-27 Nextera As pVII phage display

Also Published As

Publication number Publication date
JP2013519721A (ja) 2013-05-30
EP2536746B1 (en) 2016-04-20
WO2011101681A3 (en) 2011-12-08
WO2011101681A2 (en) 2011-08-25
RS54744B1 (sr) 2016-10-31
DK2536746T3 (en) 2016-05-30
CN102947330B (zh) 2015-09-16
HUE027952T2 (en) 2016-11-28
EP2536746A2 (en) 2012-12-26
JP5537675B2 (ja) 2014-07-02
HRP20160475T1 (hr) 2016-06-03
US9056920B2 (en) 2015-06-16
RU2012138302A (ru) 2014-03-27
CA2789492A1 (en) 2011-08-25
KR20130009782A (ko) 2013-01-23
US8828379B2 (en) 2014-09-09
SI2536746T1 (sl) 2016-09-30
KR101647176B1 (ko) 2016-08-09
ES2572388T3 (es) 2016-05-31
CA2789492C (en) 2017-04-18
CN102947330A (zh) 2013-02-27
AU2011217027A1 (en) 2012-09-06
RU2604813C2 (ru) 2016-12-10
AU2011217027B2 (en) 2015-02-05
PL2536746T3 (pl) 2016-08-31
US20130171668A1 (en) 2013-07-04
US20140349315A1 (en) 2014-11-27
CY1117697T1 (el) 2017-05-17

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Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)