GB1593288A - Bone prosthetic material - Google Patents
Bone prosthetic material Download PDFInfo
- Publication number
- GB1593288A GB1593288A GB3920577A GB3920577A GB1593288A GB 1593288 A GB1593288 A GB 1593288A GB 3920577 A GB3920577 A GB 3920577A GB 3920577 A GB3920577 A GB 3920577A GB 1593288 A GB1593288 A GB 1593288A
- Authority
- GB
- United Kingdom
- Prior art keywords
- polymer
- material according
- powder
- members
- charge
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000000463 material Substances 0.000 title claims abstract description 75
- 210000000988 bone and bone Anatomy 0.000 title claims abstract description 35
- 229920000642 polymer Polymers 0.000 claims abstract description 53
- 230000004936 stimulating effect Effects 0.000 claims abstract description 5
- 239000000843 powder Substances 0.000 claims description 25
- 230000001097 osteosynthetic effect Effects 0.000 claims description 17
- 239000001506 calcium phosphate Substances 0.000 claims description 15
- 229920001577 copolymer Polymers 0.000 claims description 15
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 claims description 14
- 239000002671 adjuvant Substances 0.000 claims description 13
- 235000011010 calcium phosphates Nutrition 0.000 claims description 11
- 239000000203 mixture Substances 0.000 claims description 11
- 150000003839 salts Chemical class 0.000 claims description 11
- 229910000389 calcium phosphate Inorganic materials 0.000 claims description 10
- RKDVKSZUMVYZHH-UHFFFAOYSA-N 1,4-dioxane-2,5-dione Chemical compound O=C1COC(=O)CO1 RKDVKSZUMVYZHH-UHFFFAOYSA-N 0.000 claims description 9
- 230000009471 action Effects 0.000 claims description 9
- 239000007787 solid Substances 0.000 claims description 9
- 229920001519 homopolymer Polymers 0.000 claims description 8
- 238000000034 method Methods 0.000 claims description 8
- 239000000178 monomer Substances 0.000 claims description 8
- 239000002245 particle Substances 0.000 claims description 8
- 230000009103 reabsorption Effects 0.000 claims description 8
- 239000008187 granular material Substances 0.000 claims description 7
- -1 phosphate anions Chemical class 0.000 claims description 7
- JJTUDXZGHPGLLC-IMJSIDKUSA-N 4511-42-6 Chemical compound C[C@@H]1OC(=O)[C@H](C)OC1=O JJTUDXZGHPGLLC-IMJSIDKUSA-N 0.000 claims description 6
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims description 6
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 claims description 6
- 229910019142 PO4 Inorganic materials 0.000 claims description 6
- 230000008901 benefit Effects 0.000 claims description 6
- 230000015572 biosynthetic process Effects 0.000 claims description 6
- 229910052791 calcium Inorganic materials 0.000 claims description 6
- 230000012010 growth Effects 0.000 claims description 6
- 239000000126 substance Substances 0.000 claims description 6
- 239000011575 calcium Substances 0.000 claims description 5
- 238000000465 moulding Methods 0.000 claims description 5
- 239000010452 phosphate Substances 0.000 claims description 5
- 238000004873 anchoring Methods 0.000 claims description 4
- 239000002131 composite material Substances 0.000 claims description 4
- 238000011049 filling Methods 0.000 claims description 4
- 238000005470 impregnation Methods 0.000 claims description 4
- 239000011777 magnesium Substances 0.000 claims description 4
- 229910052749 magnesium Inorganic materials 0.000 claims description 4
- PUZPDOWCWNUUKD-UHFFFAOYSA-M sodium fluoride Chemical compound [F-].[Na+] PUZPDOWCWNUUKD-UHFFFAOYSA-M 0.000 claims description 4
- 229910000391 tricalcium phosphate Inorganic materials 0.000 claims description 4
- 235000019731 tricalcium phosphate Nutrition 0.000 claims description 4
- 229940078499 tricalcium phosphate Drugs 0.000 claims description 4
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 claims description 3
- 150000001642 boronic acid derivatives Chemical class 0.000 claims description 3
- 239000002775 capsule Substances 0.000 claims description 3
- 150000004649 carbonic acid derivatives Chemical class 0.000 claims description 3
- 239000003054 catalyst Substances 0.000 claims description 3
- 239000000919 ceramic Substances 0.000 claims description 3
- 238000007906 compression Methods 0.000 claims description 3
- 230000006835 compression Effects 0.000 claims description 3
- 150000004673 fluoride salts Chemical class 0.000 claims description 3
- 229910052700 potassium Inorganic materials 0.000 claims description 3
- 239000011591 potassium Substances 0.000 claims description 3
- 150000004760 silicates Chemical class 0.000 claims description 3
- 210000000538 tail Anatomy 0.000 claims description 3
- 229910000838 Al alloy Inorganic materials 0.000 claims description 2
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims description 2
- 206010023204 Joint dislocation Diseases 0.000 claims description 2
- WHXSMMKQMYFTQS-UHFFFAOYSA-N Lithium Chemical compound [Li] WHXSMMKQMYFTQS-UHFFFAOYSA-N 0.000 claims description 2
- 241001465754 Metazoa Species 0.000 claims description 2
- 241001494479 Pecora Species 0.000 claims description 2
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 claims description 2
- 229910000756 V alloy Inorganic materials 0.000 claims description 2
- 239000004411 aluminium Substances 0.000 claims description 2
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 claims description 2
- BVKZGUZCCUSVTD-UHFFFAOYSA-N carbonic acid Chemical compound OC(O)=O BVKZGUZCCUSVTD-UHFFFAOYSA-N 0.000 claims description 2
- 239000000470 constituent Substances 0.000 claims description 2
- 238000005520 cutting process Methods 0.000 claims description 2
- 238000007872 degassing Methods 0.000 claims description 2
- 238000002474 experimental method Methods 0.000 claims description 2
- 238000001125 extrusion Methods 0.000 claims description 2
- 229910052588 hydroxylapatite Inorganic materials 0.000 claims description 2
- 210000003127 knee Anatomy 0.000 claims description 2
- 229910052744 lithium Inorganic materials 0.000 claims description 2
- 238000003754 machining Methods 0.000 claims description 2
- 230000003287 optical effect Effects 0.000 claims description 2
- XYJRXVWERLGGKC-UHFFFAOYSA-D pentacalcium;hydroxide;triphosphate Chemical compound [OH-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O XYJRXVWERLGGKC-UHFFFAOYSA-D 0.000 claims description 2
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 claims description 2
- 229920002959 polymer blend Polymers 0.000 claims description 2
- 230000035484 reaction time Effects 0.000 claims description 2
- 229910052708 sodium Inorganic materials 0.000 claims description 2
- 239000011734 sodium Substances 0.000 claims description 2
- 235000013024 sodium fluoride Nutrition 0.000 claims description 2
- 239000011775 sodium fluoride Substances 0.000 claims description 2
- 239000010936 titanium Substances 0.000 claims description 2
- 229910052719 titanium Inorganic materials 0.000 claims description 2
- 235000001055 magnesium Nutrition 0.000 claims 2
- 229940091250 magnesium supplement Drugs 0.000 claims 2
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 claims 1
- 229920000249 biocompatible polymer Polymers 0.000 abstract 1
- 239000000945 filler Substances 0.000 abstract 1
- 239000011256 inorganic filler Substances 0.000 abstract 1
- 239000012766 organic filler Substances 0.000 abstract 1
- 239000007943 implant Substances 0.000 description 5
- 239000011148 porous material Substances 0.000 description 5
- 238000000576 coating method Methods 0.000 description 4
- ZWEHNKRNPOVVGH-UHFFFAOYSA-N 2-Butanone Chemical compound CCC(C)=O ZWEHNKRNPOVVGH-UHFFFAOYSA-N 0.000 description 3
- 229910052751 metal Inorganic materials 0.000 description 3
- 239000002184 metal Substances 0.000 description 3
- 238000002156 mixing Methods 0.000 description 3
- 235000021317 phosphate Nutrition 0.000 description 3
- 238000011282 treatment Methods 0.000 description 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 2
- 230000008468 bone growth Effects 0.000 description 2
- 239000004568 cement Substances 0.000 description 2
- 239000011248 coating agent Substances 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 239000005020 polyethylene terephthalate Substances 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- 230000003014 reinforcing effect Effects 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 230000000638 stimulation Effects 0.000 description 2
- 229920001169 thermoplastic Polymers 0.000 description 2
- 239000004416 thermosoftening plastic Substances 0.000 description 2
- 210000001519 tissue Anatomy 0.000 description 2
- 230000009466 transformation Effects 0.000 description 2
- RYHBNJHYFVUHQT-UHFFFAOYSA-N 1,4-Dioxane Chemical compound C1COCCO1 RYHBNJHYFVUHQT-UHFFFAOYSA-N 0.000 description 1
- 229920004934 Dacron® Polymers 0.000 description 1
- VVQNEPGJFQJSBK-UHFFFAOYSA-N Methyl methacrylate Chemical compound COC(=O)C(C)=C VVQNEPGJFQJSBK-UHFFFAOYSA-N 0.000 description 1
- 229920000954 Polyglycolide Polymers 0.000 description 1
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 description 1
- 230000004913 activation Effects 0.000 description 1
- 150000001735 carboxylic acids Chemical class 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 230000000295 complement effect Effects 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
- 230000001627 detrimental effect Effects 0.000 description 1
- 238000000227 grinding Methods 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 229920006158 high molecular weight polymer Polymers 0.000 description 1
- 239000008240 homogeneous mixture Substances 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 238000011065 in-situ storage Methods 0.000 description 1
- 238000010348 incorporation Methods 0.000 description 1
- 238000001746 injection moulding Methods 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- JJTUDXZGHPGLLC-UHFFFAOYSA-N lactide Chemical compound CC1OC(=O)C(C)OC1=O JJTUDXZGHPGLLC-UHFFFAOYSA-N 0.000 description 1
- VVNXEADCOVSAER-UHFFFAOYSA-N lithium sodium Chemical compound [Li].[Na] VVNXEADCOVSAER-UHFFFAOYSA-N 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- GVALZJMUIHGIMD-UHFFFAOYSA-H magnesium phosphate Chemical class [Mg+2].[Mg+2].[Mg+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O GVALZJMUIHGIMD-UHFFFAOYSA-H 0.000 description 1
- 239000004137 magnesium phosphate Substances 0.000 description 1
- 235000010994 magnesium phosphates Nutrition 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 230000011164 ossification Effects 0.000 description 1
- 208000008798 osteoma Diseases 0.000 description 1
- 230000000704 physical effect Effects 0.000 description 1
- 239000011505 plaster Substances 0.000 description 1
- 229920001432 poly(L-lactide) Polymers 0.000 description 1
- 229920000747 poly(lactic acid) Polymers 0.000 description 1
- 229920000139 polyethylene terephthalate Polymers 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 230000000750 progressive effect Effects 0.000 description 1
- 238000002271 resection Methods 0.000 description 1
- 238000007151 ring opening polymerisation reaction Methods 0.000 description 1
- 238000007493 shaping process Methods 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 230000008733 trauma Effects 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/58—Materials at least partially resorbable by the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
- A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
- A61L27/46—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with phosphorus-containing inorganic fillers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Medicinal Chemistry (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Inorganic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Composite Materials (AREA)
- Materials Engineering (AREA)
- Materials For Medical Uses (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7628163A FR2364644B1 (fr) | 1976-09-20 | 1976-09-20 | Nouveau materiau de prothese osseuse et son application |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1593288A true GB1593288A (en) | 1981-07-15 |
Family
ID=9177829
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB3920577A Expired GB1593288A (en) | 1976-09-20 | 1977-09-20 | Bone prosthetic material |
Country Status (8)
| Country | Link |
|---|---|
| BE (1) | BE858815A (enrdf_load_stackoverflow) |
| CH (1) | CH624572A5 (enrdf_load_stackoverflow) |
| DE (1) | DE2742128A1 (enrdf_load_stackoverflow) |
| ES (1) | ES462630A1 (enrdf_load_stackoverflow) |
| FR (1) | FR2364644B1 (enrdf_load_stackoverflow) |
| GB (1) | GB1593288A (enrdf_load_stackoverflow) |
| IT (1) | IT1086088B (enrdf_load_stackoverflow) |
| NL (1) | NL185392C (enrdf_load_stackoverflow) |
Cited By (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4525495A (en) * | 1983-07-22 | 1985-06-25 | The Dow Chemical Company | Mineral filled composites |
| EP0144228A3 (en) * | 1983-12-01 | 1986-12-30 | Ethicon Inc. | Glass-filled, absorbable surgical devices |
| US4636526A (en) * | 1985-02-19 | 1987-01-13 | The Dow Chemical Company | Composites of unsintered calcium phosphates and synthetic biodegradable polymers useful as hard tissue prosthetics |
| US4661536A (en) * | 1985-02-19 | 1987-04-28 | The Dow Chemical Company | Process for the preparation of hard tissue prosthetics |
| US4698375A (en) * | 1985-02-19 | 1987-10-06 | The Dow Chemical Company | Composites of unsintered calcium phosphates and synthetic biodegradable polymers useful as hard tissue prosthetics |
| WO1988001517A1 (en) * | 1986-09-05 | 1988-03-10 | Materials Consultants Oy | Bone graft implant |
| US4842604A (en) * | 1985-02-19 | 1989-06-27 | The Dow Chemical Company | Composites of unsintered calcium phosphates and synthetic biodegradable polymers useful as hard tissue prosthetics |
| US5180765A (en) * | 1988-08-08 | 1993-01-19 | Biopak Technology, Ltd. | Biodegradable packaging thermoplastics from lactides |
| US5366756A (en) * | 1992-06-15 | 1994-11-22 | United States Surgical Corporation | Method for treating bioabsorbable implant material |
| US5424346A (en) * | 1988-08-08 | 1995-06-13 | Ecopol, Llc | Biodegradable replacement of crystal polystyrene |
| AU667516B2 (en) * | 1992-04-03 | 1996-03-28 | Bio Holdings International Limited | Bone prosthesis material containing calcium carbonate particles dispersed in a bioresorbable polymer matrix |
| US5522894A (en) * | 1984-12-14 | 1996-06-04 | Draenert; Klaus | Bone replacement material made of absorbable beads |
| EP0714666A1 (en) * | 1994-11-30 | 1996-06-05 | Ethicon, Inc. | Hard tissue bone cements and substitutes |
| US5552454A (en) * | 1988-08-09 | 1996-09-03 | Henkel Kommanditgesellschaft Auf Aktien | New materials for bone replacement and for joining bones or prostheses |
| EP1080700A3 (de) * | 1999-08-28 | 2003-05-07 | Lutz Prof.-Dr. Claes | Folie aus resorbierbarem Polymermaterial und Verfahren zur Herstellung einer solchen Folie |
| JP2008518669A (ja) * | 2004-10-29 | 2008-06-05 | スミス アンド ネフュー インコーポレーテッド | 生体吸収性ポリマー |
| US20140170235A1 (en) * | 2004-10-29 | 2014-06-19 | Smith & Nephew, Inc. | Bioabsorbable polymers |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4055862A (en) * | 1976-01-23 | 1977-11-01 | Zimmer Usa, Inc. | Human body implant of graphitic carbon fiber reinforced ultra-high molecular weight polyethylene |
| FR2439003A1 (fr) * | 1978-10-20 | 1980-05-16 | Anvar | Nouvelles pieces d'osteosynthese, leur preparation et leur application |
| DE2905878A1 (de) * | 1979-02-16 | 1980-08-28 | Merck Patent Gmbh | Implantationsmaterialien und verfahren zu ihrer herstellung |
| FR2470605A1 (en) * | 1979-12-06 | 1981-06-12 | Ispytatelny Inst Med | Bio-destructive material for bone fixation - comprises matrix of copolymer contg. hydrophilic and hydrophobic units and reinforcing fibres |
| US4496446A (en) * | 1980-10-20 | 1985-01-29 | American Cyanamid Company | Modification of polyglycolic acid structural elements to achieve variable in-vivo physical properties |
| DE3176533D1 (en) * | 1980-10-20 | 1987-12-23 | American Cyanamid Co | Modification of polyglycolic acid to achieve variable in-vivo physical properties |
| DE3374659D1 (en) * | 1983-02-03 | 1988-01-07 | Ethicon Inc | Paste for hemostasis and for temporary relief of defects in the traumatism of bones |
| US4655777A (en) * | 1983-12-19 | 1987-04-07 | Southern Research Institute | Method of producing biodegradable prosthesis and products therefrom |
| NL8402178A (nl) * | 1984-07-10 | 1986-02-03 | Rijksuniversiteit | Entstuk, geschikt voor behandeling door reconstructieve chirurgie van beschadigingen van beenachtig materiaal. |
| NL8402534A (nl) * | 1984-08-17 | 1986-03-17 | Gerrit Johannes Brinks | Materiaal, geschikt voor toepassing als implantatiemateriaal bij mens en dier ter vervanging van afwezig botweefsel, alsmede werkwijze ter bereiding van het materiaal. |
| DE3445731A1 (de) * | 1984-12-14 | 1986-06-19 | Klaus Dr.med. Dr.med.habil. 8000 München Draenert | Werkstoff und seine verwendung |
| DE3445709A1 (de) * | 1984-12-14 | 1986-06-19 | Klaus Dr.med. Dr.med.habil. 8000 München Draenert | Verschluss aus chirurgischem material |
| DE3671375D1 (de) * | 1985-02-19 | 1990-06-28 | Dow Chemical Co | Hartgewebeprothese und verfahren zu ihrer herstellung. |
| GB2181438B (en) * | 1985-10-07 | 1989-10-11 | South African Inventions | Biocompatible material |
| US4781183A (en) * | 1986-08-27 | 1988-11-01 | American Cyanamid Company | Surgical prosthesis |
| DE4120325A1 (de) * | 1991-06-20 | 1992-12-24 | Merck Patent Gmbh | Implantatwerkstoff |
| US6065476A (en) * | 1994-12-21 | 2000-05-23 | Board Of Regents, University Of Texas System | Method of enhancing surface porosity of biodegradable implants |
| DE19614421C2 (de) * | 1996-04-12 | 1999-12-16 | Biovision Gmbh | Verfahren zur Herstellung eines biodegradierbaren Knochenersatz- und Implantatwerkstoffes und biodegradierbarer Knochenersatz- und Implantatwerkstoff |
| US7012106B2 (en) | 2003-03-28 | 2006-03-14 | Ethicon, Inc. | Reinforced implantable medical devices |
| US8016865B2 (en) | 2003-09-29 | 2011-09-13 | Depuy Mitek, Inc. | Method of performing anterior cruciate ligament reconstruction using biodegradable interference screw |
| CA2637606C (en) | 2006-01-19 | 2013-03-19 | Osteotech, Inc. | Porous osteoimplant |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3443261A (en) * | 1967-09-01 | 1969-05-13 | Fmc Corp | Prosthetic structures from microcrystalline collagen |
| DE2502884A1 (de) * | 1975-01-24 | 1976-07-29 | Juergen J Dipl Phy Hildebrandt | Mittel zur biologischen implantation von knochen- und gelenkersatz |
| DE2620891C3 (de) * | 1976-05-12 | 1989-06-29 | Battelle-Institut eV, 6000 Frankfurt | Fester, resorbierbarer Knochenersatz-, Knochenverbund- oder Prothesenverankerungswerkstoff |
-
1976
- 1976-09-20 FR FR7628163A patent/FR2364644B1/fr not_active Expired
-
1977
- 1977-09-16 BE BE181005A patent/BE858815A/xx not_active IP Right Cessation
- 1977-09-17 CH CH1135177A patent/CH624572A5/fr not_active IP Right Cessation
- 1977-09-19 DE DE19772742128 patent/DE2742128A1/de active Granted
- 1977-09-20 GB GB3920577A patent/GB1593288A/en not_active Expired
- 1977-09-20 NL NL7710315A patent/NL185392C/xx not_active IP Right Cessation
- 1977-09-20 IT IT2772777A patent/IT1086088B/it active
- 1977-09-20 ES ES462630A patent/ES462630A1/es not_active Expired
Cited By (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4525495A (en) * | 1983-07-22 | 1985-06-25 | The Dow Chemical Company | Mineral filled composites |
| EP0144228A3 (en) * | 1983-12-01 | 1986-12-30 | Ethicon Inc. | Glass-filled, absorbable surgical devices |
| US5522894A (en) * | 1984-12-14 | 1996-06-04 | Draenert; Klaus | Bone replacement material made of absorbable beads |
| US4636526A (en) * | 1985-02-19 | 1987-01-13 | The Dow Chemical Company | Composites of unsintered calcium phosphates and synthetic biodegradable polymers useful as hard tissue prosthetics |
| US4661536A (en) * | 1985-02-19 | 1987-04-28 | The Dow Chemical Company | Process for the preparation of hard tissue prosthetics |
| US4698375A (en) * | 1985-02-19 | 1987-10-06 | The Dow Chemical Company | Composites of unsintered calcium phosphates and synthetic biodegradable polymers useful as hard tissue prosthetics |
| US4842604A (en) * | 1985-02-19 | 1989-06-27 | The Dow Chemical Company | Composites of unsintered calcium phosphates and synthetic biodegradable polymers useful as hard tissue prosthetics |
| WO1988001517A1 (en) * | 1986-09-05 | 1988-03-10 | Materials Consultants Oy | Bone graft implant |
| US5180765A (en) * | 1988-08-08 | 1993-01-19 | Biopak Technology, Ltd. | Biodegradable packaging thermoplastics from lactides |
| US5424346A (en) * | 1988-08-08 | 1995-06-13 | Ecopol, Llc | Biodegradable replacement of crystal polystyrene |
| US5552454A (en) * | 1988-08-09 | 1996-09-03 | Henkel Kommanditgesellschaft Auf Aktien | New materials for bone replacement and for joining bones or prostheses |
| AU667516B2 (en) * | 1992-04-03 | 1996-03-28 | Bio Holdings International Limited | Bone prosthesis material containing calcium carbonate particles dispersed in a bioresorbable polymer matrix |
| US5366756A (en) * | 1992-06-15 | 1994-11-22 | United States Surgical Corporation | Method for treating bioabsorbable implant material |
| US5697976A (en) * | 1992-06-15 | 1997-12-16 | United States Surgical Corporation | Bioabsorbable implant material |
| EP0714666A1 (en) * | 1994-11-30 | 1996-06-05 | Ethicon, Inc. | Hard tissue bone cements and substitutes |
| EP1080700A3 (de) * | 1999-08-28 | 2003-05-07 | Lutz Prof.-Dr. Claes | Folie aus resorbierbarem Polymermaterial und Verfahren zur Herstellung einer solchen Folie |
| JP2008518669A (ja) * | 2004-10-29 | 2008-06-05 | スミス アンド ネフュー インコーポレーテッド | 生体吸収性ポリマー |
| US20140170235A1 (en) * | 2004-10-29 | 2014-06-19 | Smith & Nephew, Inc. | Bioabsorbable polymers |
| US9173981B2 (en) * | 2004-10-29 | 2015-11-03 | Smith & Nephew, Inc. | Bioabsorbable polymers |
Also Published As
| Publication number | Publication date |
|---|---|
| IT1086088B (it) | 1985-05-28 |
| ES462630A1 (es) | 1978-07-01 |
| FR2364644B1 (fr) | 1981-02-06 |
| DE2742128C2 (enrdf_load_stackoverflow) | 1990-02-15 |
| FR2364644A1 (fr) | 1978-04-14 |
| NL7710315A (nl) | 1978-03-22 |
| NL185392C (nl) | 1990-04-02 |
| CH624572A5 (en) | 1981-08-14 |
| BE858815A (fr) | 1978-03-16 |
| NL185392B (nl) | 1989-11-01 |
| DE2742128A1 (de) | 1978-03-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PE20 | Patent expired after termination of 20 years |
Effective date: 19970919 |