GB1581467A - F1-d-ribofuranosyl imidazole-4,5-dicarboxylic acid derivatives - Google Patents

F1-d-ribofuranosyl imidazole-4,5-dicarboxylic acid derivatives Download PDF

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Publication number
GB1581467A
GB1581467A GB32933/77A GB3293377A GB1581467A GB 1581467 A GB1581467 A GB 1581467A GB 32933/77 A GB32933/77 A GB 32933/77A GB 3293377 A GB3293377 A GB 3293377A GB 1581467 A GB1581467 A GB 1581467A
Authority
GB
United Kingdom
Prior art keywords
conh
compounds
formula
general formula
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB32933/77A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of GB1581467A publication Critical patent/GB1581467A/en
Expired legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/052—Imidazole radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Cardiology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
GB32933/77A 1976-08-06 1977-08-05 F1-d-ribofuranosyl imidazole-4,5-dicarboxylic acid derivatives Expired GB1581467A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT585976A AT350735B (de) 1976-08-06 1976-08-06 Verfahren zur herstellung von neuen ribo- furanosyl-imidazolderivaten

Publications (1)

Publication Number Publication Date
GB1581467A true GB1581467A (en) 1980-12-17

Family

ID=3580308

Family Applications (1)

Application Number Title Priority Date Filing Date
GB32933/77A Expired GB1581467A (en) 1976-08-06 1977-08-05 F1-d-ribofuranosyl imidazole-4,5-dicarboxylic acid derivatives

Country Status (10)

Country Link
US (1) US4115641A (enExample)
JP (1) JPS5321165A (enExample)
AT (1) AT350735B (enExample)
BE (1) BE857512A (enExample)
CA (1) CA1089451A (enExample)
DE (1) DE2735458A1 (enExample)
FR (1) FR2360604A1 (enExample)
GB (1) GB1581467A (enExample)
NL (1) NL7708696A (enExample)
ZA (1) ZA774612B (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0004261B1 (de) * 1978-02-01 1982-04-28 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Neue Imidazolderivate, Verfahren zu deren Herstellung und Arzneimittel diese enthaltend
JPS55116582U (enExample) * 1979-02-13 1980-08-16
IL99124A (en) * 1990-08-10 1998-02-22 Gensia Pharma Substituted imidazole analogs of aica riboside
IL99125A0 (en) * 1990-08-10 1992-07-15 Gensia Pharma Derivatives of imidazole analog of aica riboside and their use
CA2602291C (en) 2005-03-28 2015-08-11 Pericor Therapeutics, Inc. Treatments for preventing or reducing adverse effects in a patient having decreased left ventricular function

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2034785A1 (de) * 1970-07-14 1972-01-20 Boehnnger Mannheim GmbH, 6800 Mann heim Waldhof Adenosin 5 carbonsäurederivate
DE2105560A1 (de) * 1971-02-06 1972-09-07 Boehringer Mannheim Gmbh, 6800 Mannheim Purinribonucleosid-Derivate und Verfahren zur Herstellung derselben
US3897415A (en) * 1971-06-01 1975-07-29 Icn Pharmaceuticals 5-Substituted 1,2,4-triazole-3-carboxamido nucleosides and analogs thereof
CH563405A5 (enExample) * 1971-09-10 1975-06-30 Duschinsky Robert Dr Schweiz I
US3864483A (en) * 1972-03-22 1975-02-04 Abbott Lab Adenosine-5{40 -carboxylic acid amides
US3855205A (en) * 1972-10-03 1974-12-17 Abbott Lab Process for preparing adenosine-5{40 -carboxylates
DE2342479A1 (de) * 1973-08-23 1975-03-13 Merck Patent Gmbh Ribonucleosid-5'-nitrate und verfahren zu ihrer herstellung
LU72078A1 (enExample) * 1975-03-18 1977-01-31
CH658188A5 (de) * 1984-03-23 1986-10-31 Ciba Geigy Ag Lagerstabile schnellzerfallende pharmazeutische presslinge.

Also Published As

Publication number Publication date
BE857512A (fr) 1978-02-06
DE2735458A1 (de) 1978-02-09
FR2360604B1 (enExample) 1979-07-13
CA1089451A (en) 1980-11-11
US4115641A (en) 1978-09-19
FR2360604A1 (fr) 1978-03-03
ATA585976A (de) 1978-11-15
AT350735B (de) 1979-06-11
ZA774612B (en) 1978-06-28
JPS5321165A (en) 1978-02-27
NL7708696A (nl) 1978-02-08

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee