GB1554050A - Prostacyclin derivatives - Google Patents
Prostacyclin derivativesInfo
- Publication number
- GB1554050A GB1554050A GB36450/77A GB3645077A GB1554050A GB 1554050 A GB1554050 A GB 1554050A GB 36450/77 A GB36450/77 A GB 36450/77A GB 3645077 A GB3645077 A GB 3645077A GB 1554050 A GB1554050 A GB 1554050A
- Authority
- GB
- United Kingdom
- Prior art keywords
- formula
- image
- compounds
- compound
- mercury
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000003815 prostacyclins Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 5
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 abstract 2
- 229940121363 anti-inflammatory agent Drugs 0.000 abstract 1
- 239000002260 anti-inflammatory agent Substances 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 210000001772 blood platelet Anatomy 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- QSHDDOUJBYECFT-UHFFFAOYSA-N mercury Chemical compound [Hg] QSHDDOUJBYECFT-UHFFFAOYSA-N 0.000 abstract 1
- 229910052753 mercury Inorganic materials 0.000 abstract 1
- 229940100892 mercury compound Drugs 0.000 abstract 1
- 150000002731 mercury compounds Chemical class 0.000 abstract 1
- 230000002829 reductive effect Effects 0.000 abstract 1
- 208000010110 spontaneous platelet aggregation Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
- C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
- C07C405/0016—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing only hydroxy, etherified or esterified hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
- C07C405/0041—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing nitrogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/94—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyrane Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US78814477A | 1977-04-19 | 1977-04-19 | |
| US78814377A | 1977-04-19 | 1977-04-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1554050A true GB1554050A (en) | 1979-10-17 |
Family
ID=27120750
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB36450/77A Expired GB1554050A (en) | 1977-04-19 | 1977-09-01 | Prostacyclin derivatives |
Country Status (9)
| Country | Link |
|---|---|
| JP (1) | JPS53132573A (enrdf_load_stackoverflow) |
| AU (1) | AU509357B2 (enrdf_load_stackoverflow) |
| CA (1) | CA1184906A (enrdf_load_stackoverflow) |
| CH (1) | CH636347A5 (enrdf_load_stackoverflow) |
| DE (1) | DE2746932A1 (enrdf_load_stackoverflow) |
| FR (1) | FR2387975A1 (enrdf_load_stackoverflow) |
| GB (1) | GB1554050A (enrdf_load_stackoverflow) |
| NL (1) | NL7800011A (enrdf_load_stackoverflow) |
| SE (1) | SE434266B (enrdf_load_stackoverflow) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4206127A (en) * | 1977-11-23 | 1980-06-03 | Miles Laboratories, Inc. | 5,6-Dihydro analogues of prostaglandin I2 |
| JPH02294718A (ja) * | 1989-05-09 | 1990-12-05 | Fujitsu Ltd | ディジタル信号入力回路 |
| KR100830061B1 (ko) * | 1999-10-15 | 2008-05-16 | 수캄포 아게 | 이환식 화합물 조성물 및 이의 안정화 방법 |
| KR101768235B1 (ko) | 2009-07-28 | 2017-08-14 | 오노 야꾸힝 고교 가부시키가이샤 | 이환식 화합물 및 이의 의약 용도 |
| EP2669280B1 (en) * | 2011-01-27 | 2016-04-27 | ONO Pharmaceutical Co., Ltd. | Bicyclic compound and use thereof for medical purposes |
| WO2012102357A1 (ja) * | 2011-01-27 | 2012-08-02 | 小野薬品工業株式会社 | 二環式化合物およびその医薬用途 |
| US10899729B2 (en) | 2016-06-30 | 2021-01-26 | Ono Pharmaceutical Co.. Ltd. | Method for producing bicyclic compound |
-
1977
- 1977-08-22 CA CA000285239A patent/CA1184906A/en not_active Expired
- 1977-08-23 SE SE7709477A patent/SE434266B/xx not_active IP Right Cessation
- 1977-08-25 AU AU28206/77A patent/AU509357B2/en not_active Expired
- 1977-09-01 GB GB36450/77A patent/GB1554050A/en not_active Expired
- 1977-10-04 JP JP11872477A patent/JPS53132573A/ja active Granted
- 1977-10-19 DE DE19772746932 patent/DE2746932A1/de active Granted
- 1977-10-24 CH CH1293077A patent/CH636347A5/de not_active IP Right Cessation
- 1977-10-28 FR FR7732557A patent/FR2387975A1/fr active Granted
-
1978
- 1978-01-02 NL NL7800011A patent/NL7800011A/xx not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| DE2746932A1 (de) | 1978-11-02 |
| AU509357B2 (en) | 1980-05-08 |
| JPS6151597B2 (enrdf_load_stackoverflow) | 1986-11-10 |
| SE434266B (sv) | 1984-07-16 |
| FR2387975A1 (fr) | 1978-11-17 |
| AU2820677A (en) | 1979-03-01 |
| CH636347A5 (en) | 1983-05-31 |
| JPS53132573A (en) | 1978-11-18 |
| CA1184906A (en) | 1985-04-02 |
| DE2746932C2 (enrdf_load_stackoverflow) | 1988-03-31 |
| FR2387975B1 (enrdf_load_stackoverflow) | 1980-08-08 |
| NL7800011A (nl) | 1978-10-23 |
| SE7709477L (sv) | 1978-10-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |