GB1541321A - 2,3-dihydroimidazo(2,1-b)thiazole derivatives and process for their preparation - Google Patents

2,3-dihydroimidazo(2,1-b)thiazole derivatives and process for their preparation

Info

Publication number
GB1541321A
GB1541321A GB9517/76A GB951776A GB1541321A GB 1541321 A GB1541321 A GB 1541321A GB 9517/76 A GB9517/76 A GB 9517/76A GB 951776 A GB951776 A GB 951776A GB 1541321 A GB1541321 A GB 1541321A
Authority
GB
United Kingdom
Prior art keywords
dihydroimidazo
preparation
thiazole derivatives
thiazole
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB9517/76A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Metabio
Original Assignee
Metabio
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Metabio filed Critical Metabio
Priority to GB9517/76A priority Critical patent/GB1541321A/en
Priority to CH259777A priority patent/CH598267A5/xx
Priority to LU76879A priority patent/LU76879A1/xx
Priority to IL51581A priority patent/IL51581A/xx
Priority to IE467/77A priority patent/IE44280B1/en
Priority to ZA00771303A priority patent/ZA771303B/xx
Priority to FR7706434A priority patent/FR2343748A1/fr
Priority to CA273,239A priority patent/CA1074324A/en
Priority to US05/774,497 priority patent/US4110460A/en
Priority to DE19772709639 priority patent/DE2709639A1/de
Priority to SE7702503A priority patent/SE431653B/xx
Priority to NL7702446A priority patent/NL7702446A/xx
Priority to ES456575A priority patent/ES456575A1/es
Priority to BG035610A priority patent/BG28262A3/xx
Priority to YU00619/77A priority patent/YU61977A/xx
Priority to PT66278A priority patent/PT66278B/pt
Priority to RO7789635A priority patent/RO71301A/ro
Priority to PL1977196539A priority patent/PL102603B1/pl
Priority to DK104677A priority patent/DK144702C/da
Priority to CS771589A priority patent/CS190341B2/cs
Priority to FI770759A priority patent/FI62313C/fi
Priority to BE175621A priority patent/BE852259A/xx
Priority to HU77ME00002049A priority patent/HU172685B/hu
Priority to NO770841A priority patent/NO150884C/no
Priority to JP52026581A priority patent/JPS5927357B2/ja
Priority to AU23156/77A priority patent/AU503912B2/en
Priority to SU772459651A priority patent/SU629882A3/ru
Priority to AT164477A priority patent/AT352716B/de
Publication of GB1541321A publication Critical patent/GB1541321A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
GB9517/76A 1976-03-10 1976-03-10 2,3-dihydroimidazo(2,1-b)thiazole derivatives and process for their preparation Expired GB1541321A (en)

Priority Applications (28)

Application Number Priority Date Filing Date Title
GB9517/76A GB1541321A (en) 1976-03-10 1976-03-10 2,3-dihydroimidazo(2,1-b)thiazole derivatives and process for their preparation
CH259777A CH598267A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1976-03-10 1977-03-02
LU76879A LU76879A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1976-03-10 1977-03-02
IL51581A IL51581A (en) 1976-03-10 1977-03-02 5,6-bis-phenyl-2,3-diydro-imidazo(2,1-b)thiazole derivatives their preparation and pharmaceutical compositions containg them
IE467/77A IE44280B1 (en) 1976-03-10 1977-03-03 2,3-dihydro-imidazo/2,1-b-thiazole derivatives and process for their preparation
ZA00771303A ZA771303B (en) 1976-03-10 1977-03-04 New 2,3-dihydro-amidazo(2,1-b)-thiazole derivatives and process for their preparation
FR7706434A FR2343748A1 (fr) 1976-03-10 1977-03-04 Derives de 2,3-dihydro imidazo (2,1-b) thiazole, leur procede de preparation et leur application en therapeutique
CA273,239A CA1074324A (en) 1976-03-10 1977-03-04 Process for the preparation of new 2,3-dihydro-imidazo (2,1-b)-thiazole derivatives
US05/774,497 US4110460A (en) 1976-03-10 1977-03-04 2,3-Dihydro-imidazo[2,1-b]-thiazole derivatives and applications thereof
DE19772709639 DE2709639A1 (de) 1976-03-10 1977-03-05 Derivate von 2,3-dihydroimidazo eckige klammer auf 2,1-b eckige klammer zu thiazol, verfahren zu ihrer herstellung und sie enthaltende arzneimittel
SE7702503A SE431653B (sv) 1976-03-10 1977-03-07 Forfarande for framstellning av 2,3-dihydro-imidazo/2,1-b/tiazolderivat
NL7702446A NL7702446A (nl) 1976-03-10 1977-03-07 Werkwijze ter bereiding van nieuwe 2.3-dihydro- -imidazo(2.1-b)thiazolen, werkwijze ter berei- ding van farmaceutische preparaten en aldus verkregen gevormde preparaten.
ES456575A ES456575A1 (es) 1976-03-10 1977-03-07 Procedimiento de preparacion de derivados del 2,3-dihidro imidazo (2,1-b)tiazol.
BG035610A BG28262A3 (bg) 1976-03-10 1977-03-08 Метод за получаване на 2,3-дихидроимидазо/2,1-б/ тиазолови производни
YU00619/77A YU61977A (en) 1976-03-10 1977-03-08 Process for obtaining new derivatives of 2,3-dihydro-imidazo-(2,1-b)thiazole
PT66278A PT66278B (fr) 1976-03-10 1977-03-08 Procede de preparation de nouveaux derives de 2,3-dihydro imidazo /2,1-b/ thiazole
RO7789635A RO71301A (ro) 1976-03-10 1977-03-09 Procedeu de preparare de derivati de 2,3-dihidro-imidazo(2,1-b)tiazoli
PL1977196539A PL102603B1 (pl) 1976-03-10 1977-03-09 Sposob wytwarzania nowych pochodnych 2,3-dwuhydroimidazo/2,1-b/tiazolu
DK104677A DK144702C (da) 1976-03-10 1977-03-09 Analogifremgangsmaade til fremstilling af 2,3-dihydro-imidazo(2,1-b)-thiazolderivater
CS771589A CS190341B2 (en) 1976-03-10 1977-03-09 Method of producing new derivatives of 2,3-dihydro-imidazo/2,1-b/thiazole
FI770759A FI62313C (fi) 1976-03-10 1977-03-09 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 2,3-dihydroimidazo(2,1-b)tiazolderivat
BE175621A BE852259A (fr) 1976-03-10 1977-03-09 Derives de 2,3-dihydro (2,1-b) thiazole
HU77ME00002049A HU172685B (hu) 1976-03-10 1977-03-09 Sposob poluchenija proizvodnykh 2,3-digidro-imidazo/2,1-b/tiazola
NO770841A NO150884C (no) 1976-03-10 1977-03-09 Analogifremgangsmaate for fremstilling av nye, terapeutisk aktive imidazotiazolderivater
JP52026581A JPS5927357B2 (ja) 1976-03-10 1977-03-10 新規チアゾ−ル誘導体
AU23156/77A AU503912B2 (en) 1976-03-10 1977-03-10 2, 3-dihydro-imidazo (2, 1-b) thiazole derivatives
SU772459651A SU629882A3 (ru) 1976-03-10 1977-03-10 Способ получени производных 2,3-дигидроимидазо(2,1- )тиазола или их солей
AT164477A AT352716B (de) 1976-03-10 1977-03-10 Verfahren zur herstellung von neuen derivaten des 2,3-dihydroimidazo (2,1-b)thiazols

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB9517/76A GB1541321A (en) 1976-03-10 1976-03-10 2,3-dihydroimidazo(2,1-b)thiazole derivatives and process for their preparation

Publications (1)

Publication Number Publication Date
GB1541321A true GB1541321A (en) 1979-02-28

Family

ID=9873507

Family Applications (1)

Application Number Title Priority Date Filing Date
GB9517/76A Expired GB1541321A (en) 1976-03-10 1976-03-10 2,3-dihydroimidazo(2,1-b)thiazole derivatives and process for their preparation

Country Status (28)

Country Link
US (1) US4110460A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPS5927357B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) AT352716B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU503912B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BE (1) BE852259A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BG (1) BG28262A3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA1074324A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CH (1) CH598267A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CS (1) CS190341B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE2709639A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK144702C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES456575A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FI (1) FI62313C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FR (1) FR2343748A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GB (1) GB1541321A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HU (1) HU172685B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IE (1) IE44280B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IL (1) IL51581A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
LU (1) LU76879A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NL (1) NL7702446A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NO (1) NO150884C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PL (1) PL102603B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PT (1) PT66278B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
RO (1) RO71301A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SE (1) SE431653B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SU (1) SU629882A3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
YU (1) YU61977A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ZA (1) ZA771303B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4204067A (en) * 1976-09-24 1980-05-20 Adhikary Parimal K Derivatives of imidazo[2,1-b] thiazole
US4263311A (en) * 1976-09-27 1981-04-21 Smithkline Corporation 5,6-Phenyl-2,3-dihydroimidazo [2,1-b] thiazoles
LU77703A1 (de) * 1977-07-07 1979-03-26 Ciba Geigy Ag Verfahren zur herstellung von bicyclischen thia-diaza-verbindungen
US4153706A (en) 1978-02-13 1979-05-08 Smithkline Corporation 6-Hydroxy-5,6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazoles
US4175127A (en) * 1978-09-27 1979-11-20 Smithkline Corporation Pyridyl substituted 2,3-dihydroimidazo[2,1-b]thiazoles
PL221188A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1979-01-05 1980-12-01 Ciba Geigy Ag
US4364942A (en) * 1979-06-21 1982-12-21 Janssen Pharmaceutica N.V. 2,3-Dihydro-imidazo (2,1-b)benzothiazoles compositions useful as anti-parkinsonism agents
FR2463774A1 (fr) * 1979-08-21 1981-02-27 Yamanouchi Pharma Co Ltd Derives du 2-phenylimidazo(2,1-b)benzothiazole
FR2479831A1 (fr) * 1980-04-08 1981-10-09 Synthelabo Derives de thiazole, leur preparation et leur application en therapeutique
US4327221A (en) * 1980-10-15 1982-04-27 American Home Products Corporation 2-Substituted-3-hydroxythiazolo(2,3-8)-thiazolium salts and mesoionic didehydro derivatives thereof
US4719218A (en) * 1985-12-12 1988-01-12 Smithkline Beckman Corporation Pyrrolo[1,2-a]imidazole and pyrrolo[1,2-a]pyridine derivatives and their use as 5-lipoxygenase pathway inhibitor
ZW24186A1 (en) * 1985-12-12 1987-07-08 Smithkline Beckman Corp Inhibition of the 5-lipoxygenase pathway
US4751310A (en) * 1985-12-12 1988-06-14 Smithkline Beckman Corporation Inhibition of the 5-lipoxygenase pathway
US5145858A (en) * 1985-12-12 1992-09-08 Smithkline Beecham Corp. Pyrrolo [1,2-a] imidazole and imidazo [1,2a] pyridine derivatives and their use as 5-lipoxygenase pathway inhibitors
US5002941A (en) * 1985-12-12 1991-03-26 Smithkline Beecham Corporation Pyrrolo(1,2-a)imidazole and imidazo(1,2-a)pyridine derivatives and their use as 5-lipoxygenase pathway inhibitors
US5134150A (en) * 1985-12-12 1992-07-28 Smithkline Beecham Corporation Inhibition of the 5-lipoxygenase pathway
US4794114A (en) * 1986-08-19 1988-12-27 Smithkline Beckman Corporation Inhibition of interleukin-1 production by monocytes and/or macrophages
US5630014A (en) * 1993-10-27 1997-05-13 Nec Corporation Gain controller with automatic adjustment using integration energy values
US6127387A (en) * 1996-12-10 2000-10-03 Thomas Jefferson University Use of CD4-binding small molecules to inhibit immune responses
WO2007034282A2 (en) * 2005-09-19 2007-03-29 Pfizer Products Inc. Diaryl-imidazole compounds condensed with a heterocycle as c3a receptor antagonists

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL131034C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1964-05-11
US3455924A (en) * 1967-02-08 1969-07-15 Upjohn Co Dianisylimidazoles
NL164285C (nl) * 1968-01-09 1980-12-15 Rhone Poulenc Sa Werkwijze ter bereiding van een farmaceutisch preparaat, dat een imidazoÿ2.1-bÿthiazoolderivaat bevat, de gevormde farmaceutische preparaten, alsmede werkwijze voor het bereiden van dit imidazoÿ2.1-bÿthiazoolderivaat.

Also Published As

Publication number Publication date
LU76879A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1977-07-12
NO150884B (no) 1984-09-24
US4110460A (en) 1978-08-29
YU61977A (en) 1982-06-30
ZA771303B (en) 1978-01-25
CA1074324A (en) 1980-03-25
BE852259A (fr) 1977-09-09
IL51581A0 (en) 1977-05-31
ATA164477A (de) 1979-03-15
PT66278A (fr) 1977-04-01
DK104677A (da) 1977-09-11
SE431653B (sv) 1984-02-20
NL7702446A (nl) 1977-09-13
SU629882A3 (ru) 1978-10-25
AT352716B (de) 1979-10-10
NO150884C (no) 1985-01-09
DK144702B (da) 1982-05-17
PL102603B1 (pl) 1979-04-30
CH598267A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1978-04-28
BG28262A3 (bg) 1980-03-25
CS190341B2 (en) 1979-05-31
DK144702C (da) 1982-10-11
SE7702503L (sv) 1977-09-11
RO71301A (ro) 1981-11-24
AU2315677A (en) 1978-09-14
IE44280L (en) 1977-09-10
IL51581A (en) 1980-02-29
FI62313C (fi) 1982-12-10
JPS52136195A (en) 1977-11-14
FR2343748B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1980-07-18
HU172685B (hu) 1978-11-28
NO770841L (no) 1977-09-13
IE44280B1 (en) 1981-09-23
DE2709639A1 (de) 1977-09-15
ES456575A1 (es) 1978-02-16
JPS5927357B2 (ja) 1984-07-05
FR2343748A1 (fr) 1977-10-07
FI62313B (fi) 1982-08-31
FI770759A7 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1977-09-11
PT66278B (fr) 1978-08-08
AU503912B2 (en) 1979-09-27

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee