GB1533529A - 4-amino-6,7-dimethoxy-2-(4-(heterocyclo-carbonyl)piperazin-1-yl)quinazolines - Google Patents

4-amino-6,7-dimethoxy-2-(4-(heterocyclo-carbonyl)piperazin-1-yl)quinazolines

Info

Publication number
GB1533529A
GB1533529A GB6704/77A GB670477A GB1533529A GB 1533529 A GB1533529 A GB 1533529A GB 6704/77 A GB6704/77 A GB 6704/77A GB 670477 A GB670477 A GB 670477A GB 1533529 A GB1533529 A GB 1533529A
Authority
GB
United Kingdom
Prior art keywords
quinazolines
heterocyclo
piperazin
dimethoxy
carbonyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB6704/77A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Co
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/658,979 external-priority patent/US4001238A/en
Priority claimed from US05/658,961 external-priority patent/US4001237A/en
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of GB1533529A publication Critical patent/GB1533529A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
GB6704/77A 1976-02-18 1977-02-17 4-amino-6,7-dimethoxy-2-(4-(heterocyclo-carbonyl)piperazin-1-yl)quinazolines Expired GB1533529A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US05/658,979 US4001238A (en) 1976-02-18 1976-02-18 1,3,4-oxadiazole amides
US05/658,961 US4001237A (en) 1976-02-18 1976-02-18 Oxazole, isoxazole, thiazole and isothiazole amides

Publications (1)

Publication Number Publication Date
GB1533529A true GB1533529A (en) 1978-11-29

Family

ID=27097727

Family Applications (1)

Application Number Title Priority Date Filing Date
GB6704/77A Expired GB1533529A (en) 1976-02-18 1977-02-17 4-amino-6,7-dimethoxy-2-(4-(heterocyclo-carbonyl)piperazin-1-yl)quinazolines

Country Status (16)

Country Link
JP (1) JPS584716B2 (xx)
CA (1) CA1081228A (xx)
CH (1) CH635838A5 (xx)
CY (1) CY1122A (xx)
DE (1) DE2707067A1 (xx)
DK (1) DK65177A (xx)
FI (1) FI770485A (xx)
FR (1) FR2348924A1 (xx)
GB (1) GB1533529A (xx)
IE (1) IE44614B1 (xx)
KE (1) KE3155A (xx)
LU (1) LU76802A1 (xx)
MY (1) MY8200110A (xx)
NL (1) NL7701753A (xx)
SE (1) SE7701732L (xx)
YU (4) YU45477A (xx)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1018879A1 (en) * 1996-02-02 2000-07-19 Nitromed, Inc. Nitrosated and nitrosylated alpha-adrenergic receptor antagonist compounds, compositions and their uses
EP1852422A2 (en) * 1996-02-02 2007-11-07 Nitromed, Inc. Nitrosated and nitorsylated alpha-andrenergic receptor antagonist compounds, compositions and their uses

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5791987A (en) * 1980-11-26 1982-06-08 Sankyo Co Ltd Aminoquinazoline derivative and its preparation
AU2003246571B2 (en) * 2002-06-29 2008-06-26 Zentaris Gmbh Arylcarbonylpiperazines and heteroarylcarbonylpiperazines and the use thereof for treating benign and malignant tumour diseases

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1018879A1 (en) * 1996-02-02 2000-07-19 Nitromed, Inc. Nitrosated and nitrosylated alpha-adrenergic receptor antagonist compounds, compositions and their uses
EP1018879A4 (en) * 1996-02-02 2002-07-24 Nitromed Inc NITROSIZED AND NITROSYLATED ALPHA ADRENO RECEPTORE ANTAGONISTS, PREPARATIONS AND THEIR USE
EP1852422A2 (en) * 1996-02-02 2007-11-07 Nitromed, Inc. Nitrosated and nitorsylated alpha-andrenergic receptor antagonist compounds, compositions and their uses
EP1852422A3 (en) * 1996-02-02 2007-11-21 Nitromed, Inc. Nitrosated and nitorsylated alpha-andrenergic receptor antagonist compounds, compositions and their uses

Also Published As

Publication number Publication date
AU2242677A (en) 1978-07-06
FR2348924A1 (fr) 1977-11-18
SE7701732L (sv) 1977-08-19
JPS584716B2 (ja) 1983-01-27
DK65177A (da) 1977-08-19
YU45477A (en) 1982-10-31
FR2348924B1 (xx) 1980-05-09
IE44614L (en) 1977-08-18
DE2707067A1 (de) 1977-08-25
YU161182A (en) 1982-10-31
LU76802A1 (xx) 1977-09-12
KE3155A (en) 1981-09-18
IE44614B1 (en) 1982-01-27
NL7701753A (nl) 1977-08-22
YU267780A (en) 1983-06-30
MY8200110A (en) 1982-12-31
CY1122A (en) 1981-12-04
JPS52102286A (en) 1977-08-27
FI770485A (xx) 1977-08-19
YU161282A (en) 1982-10-31
CH635838A5 (en) 1983-04-29
CA1081228A (en) 1980-07-08

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee