GB1529782A - Disubstituted derivatives of piperazine a method of preparation of the said derivatives and therapeutic applications thereof - Google Patents
Disubstituted derivatives of piperazine a method of preparation of the said derivatives and therapeutic applications thereofInfo
- Publication number
- GB1529782A GB1529782A GB1317377A GB1317377A GB1529782A GB 1529782 A GB1529782 A GB 1529782A GB 1317377 A GB1317377 A GB 1317377A GB 1317377 A GB1317377 A GB 1317377A GB 1529782 A GB1529782 A GB 1529782A
- Authority
- GB
- United Kingdom
- Prior art keywords
- derivatives
- piperazine
- preparation
- therapeutic applications
- disubstituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
- C07D295/104—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/108—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/092—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings with aromatic radicals attached to the chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
- C07D317/54—Radicals substituted by oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7613592A FR2350100A1 (fr) | 1976-05-06 | 1976-05-06 | Derives disubstitues de la piperazine, leur procede de preparation et leurs applications therapeutiques |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1529782A true GB1529782A (en) | 1978-10-25 |
Family
ID=9172778
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB1317377A Expired GB1529782A (en) | 1976-05-06 | 1977-03-29 | Disubstituted derivatives of piperazine a method of preparation of the said derivatives and therapeutic applications thereof |
Country Status (4)
Country | Link |
---|---|
DE (1) | DE2719246C2 (fr) |
ES (1) | ES456988A1 (fr) |
FR (1) | FR2350100A1 (fr) |
GB (1) | GB1529782A (fr) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0194336A2 (fr) * | 1985-03-11 | 1986-09-17 | Taiyo Pharmaceutical Industry Co., Ltd. | Formulation orale de mobenzoxamine |
WO1992001686A1 (fr) * | 1990-07-26 | 1992-02-06 | Novo Nordisk A/S | Piperazines 1,4-bisubstituees |
US5276035A (en) * | 1990-07-26 | 1994-01-04 | Novo Nordisk A/S | 1,4-disubstituted piperazines |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0061453A1 (fr) * | 1980-06-16 | 1982-10-06 | AB Ferrosan | Diphenylbutyl-1-acylpiperazines |
NL8202636A (nl) * | 1982-06-29 | 1984-01-16 | Gist Brocades Nv | Piperazinederivaten, werkwijzen ter bereiding daarvan en farmaceutische preparaten die deze verbindingen bevatten. |
FR2601366B1 (fr) * | 1986-07-10 | 1988-11-25 | Andre Buzas | Derives de la benzhydryloxyethyl-piperazine, procedes d'obtention et de compositions pharmaceutiques les contenant. |
FR2603583B1 (fr) * | 1986-09-05 | 1988-12-09 | Andre Buzas | Derives de la benzhydryloxyethyl-piperidine, procede d'obtention et compositions pharmaceutiques les contenant |
EP0775128A1 (fr) * | 1995-06-07 | 1997-05-28 | Dade Chemistry Systems Inc. | Preparations d'immunogenes et d'autres conjugues de medicaments |
JP2001506978A (ja) * | 1996-10-31 | 2001-05-29 | アメリカ合衆国 | 置換1―[2[ビス(アリール)メトキシ]エチル]―ピペラジンおよび―ホモピペラジンのヒドロキシル化類似物の持続性放出誘導体およびそのドパミン再アップテイクの非競合的拮抗物質としての使用 |
-
1976
- 1976-05-06 FR FR7613592A patent/FR2350100A1/fr active Granted
-
1977
- 1977-03-18 ES ES456988A patent/ES456988A1/es not_active Expired
- 1977-03-29 GB GB1317377A patent/GB1529782A/en not_active Expired
- 1977-04-29 DE DE19772719246 patent/DE2719246C2/de not_active Expired
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0194336A2 (fr) * | 1985-03-11 | 1986-09-17 | Taiyo Pharmaceutical Industry Co., Ltd. | Formulation orale de mobenzoxamine |
EP0194336A3 (fr) * | 1985-03-11 | 1987-07-01 | Taiyo Pharmaceutical Industry Co., Ltd. | Formulation orale de mobenzoxamine |
WO1992001686A1 (fr) * | 1990-07-26 | 1992-02-06 | Novo Nordisk A/S | Piperazines 1,4-bisubstituees |
US5177077A (en) * | 1990-07-26 | 1993-01-05 | Novo Nordisk A/S | 1,4-disubstituted piperazines |
US5276035A (en) * | 1990-07-26 | 1994-01-04 | Novo Nordisk A/S | 1,4-disubstituted piperazines |
Also Published As
Publication number | Publication date |
---|---|
DE2719246C2 (de) | 1984-11-08 |
ES456988A1 (es) | 1978-02-16 |
FR2350100B1 (fr) | 1979-04-27 |
DE2719246A1 (de) | 1977-11-10 |
FR2350100A1 (fr) | 1977-12-02 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
PL257774A1 (en) | Insecticide | |
ATE65994T1 (de) | Insektentoetende pyrazoline. | |
GB1529782A (en) | Disubstituted derivatives of piperazine a method of preparation of the said derivatives and therapeutic applications thereof | |
BG33886A3 (en) | Method for heterocyclic compounds producing | |
JPS57102885A (en) | Novel derivatives of 1-(2-,3- or 4-quinolyl)- 2-or -3-(2- or 3-piperidyl or -pyrrolidinyl) ethanone or propanone, manufacture and medicine using same | |
MA19046A1 (fr) | Nouveau derive d'acides i-(cyclohexyl) -4-aryl-4-piperidinecarboxylique . | |
ATE25079T1 (de) | 2-(trisubstituierte phenyl-imino)-imidazoline. | |
FR2422624A1 (fr) | Nouveaux agents anticholinergiques doues d'activite antisecretoire, leur procede de preparation et leurs utilisations | |
BG96513A (bg) | Заместени 4-фенил-4-пиперидинкарбоксамиди с локален обезболяващ и болкоуспокояващ ефект и метод за тяхното получаване | |
BG41126A3 (en) | Method for preparing benzamides | |
IT8421471A1 (it) | Derivato di 1-[bis-{4-fluorofenil)metil]-4-(3-fenil-2-propenil)-esaidro-1h-1,4-diazepina ad attivita' calcio antagonista, sua preparazione e composizioni che lo contengono | |
FR2403995A1 (fr) | 1-(4,4-bis (4-fluorophenyl) butyl)-4-phenoxy-1,2,3,6-tetrahydropyridines et piperidines correspondantes ainsi que leur application pharmaceutique | |
BG35898A3 (en) | Method for preparing 1- (4- aryl- cyclohexyl)- piperidines | |
ATE69220T1 (de) | Sechsgliedrige heterocyclische derivate von n'substituiertenn,n'-diacylhydrazinen. | |
NO166542C (no) | Kobolt-basert superlegering og anvendelse av denne. | |
JPS56166143A (en) | Manufacture of 1-(4-hydroxy-phenyl)-butane- 3-one and novel intermediate thereby | |
FR2434806A1 (fr) | 1-(2,6-dihalobenzoyl)-3-(2-pyridinyl-5-substitue) urees, leur preparation et leur utilisation comme insecticides | |
ES8504793A1 (es) | Un procedimiento para la preparacion de una quinazolina | |
EG15454A (en) | Process for preparing of 1-(trialkoxybenzyl)piperazines | |
ATE121737T1 (de) | Herstellung von enantiomeren des dropropizins. | |
FR2446824A1 (fr) | 4,5,6,7-tetrahydro-1h(ou 2h)-indazoles a groupement amino et leur utilisation therapeutique | |
ATE94550T1 (de) | Mono- und diepoxidderivate von 23-deoxy-ll-f28249-verbindungen. | |
IT8045205A0 (it) | Miglioramento di piperazine nsostituite con attivita' brancospasmolitiche | |
SU1136450A1 (ru) | 4-(2'-Нафтиламино-4'-хлорфенил)-метилантипирин, проявляющий анальгетическую активность | |
SU788646A1 (ru) | 1-Ариламино-3-фенилиндолиноны-2, проявляющие анальгетическую активность |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed | ||
PCNP | Patent ceased through non-payment of renewal fee |