FR2350100A1 - Derives disubstitues de la piperazine, leur procede de preparation et leurs applications therapeutiques - Google Patents

Derives disubstitues de la piperazine, leur procede de preparation et leurs applications therapeutiques

Info

Publication number
FR2350100A1
FR2350100A1 FR7613592A FR7613592A FR2350100A1 FR 2350100 A1 FR2350100 A1 FR 2350100A1 FR 7613592 A FR7613592 A FR 7613592A FR 7613592 A FR7613592 A FR 7613592A FR 2350100 A1 FR2350100 A1 FR 2350100A1
Authority
FR
France
Prior art keywords
disubstitute
piperazine
derivatives
preparation
therapeutic applications
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7613592A
Other languages
English (en)
Other versions
FR2350100B1 (fr
Inventor
Andre Buzas
Jean-Marie Melon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SAUBA LAB
Original Assignee
SAUBA LAB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SAUBA LAB filed Critical SAUBA LAB
Priority to FR7613592A priority Critical patent/FR2350100A1/fr
Priority to ES456988A priority patent/ES456988A1/es
Priority to GB1317377A priority patent/GB1529782A/en
Priority to DE19772719246 priority patent/DE2719246C2/de
Publication of FR2350100A1 publication Critical patent/FR2350100A1/fr
Application granted granted Critical
Publication of FR2350100B1 publication Critical patent/FR2350100B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
    • C07D295/104—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/108—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/092—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings with aromatic radicals attached to the chain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/54—Radicals substituted by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR7613592A 1976-05-06 1976-05-06 Derives disubstitues de la piperazine, leur procede de preparation et leurs applications therapeutiques Granted FR2350100A1 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
FR7613592A FR2350100A1 (fr) 1976-05-06 1976-05-06 Derives disubstitues de la piperazine, leur procede de preparation et leurs applications therapeutiques
ES456988A ES456988A1 (es) 1976-05-06 1977-03-18 Procedimiento para preparar derivados disustituidos de pipe-razina.
GB1317377A GB1529782A (en) 1976-05-06 1977-03-29 Disubstituted derivatives of piperazine a method of preparation of the said derivatives and therapeutic applications thereof
DE19772719246 DE2719246C2 (de) 1976-05-06 1977-04-29 Dimaleat von 1[2(4-Methoxybenzhydryloxyäthyl)]-4-[3(4-fluorbenzoyl)-propyl]-piperazin, Verfahren zu dessen Herstellung und diese Verbindung enthaltendes Arzneimittel

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7613592A FR2350100A1 (fr) 1976-05-06 1976-05-06 Derives disubstitues de la piperazine, leur procede de preparation et leurs applications therapeutiques

Publications (2)

Publication Number Publication Date
FR2350100A1 true FR2350100A1 (fr) 1977-12-02
FR2350100B1 FR2350100B1 (fr) 1979-04-27

Family

ID=9172778

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7613592A Granted FR2350100A1 (fr) 1976-05-06 1976-05-06 Derives disubstitues de la piperazine, leur procede de preparation et leurs applications therapeutiques

Country Status (4)

Country Link
DE (1) DE2719246C2 (fr)
ES (1) ES456988A1 (fr)
FR (1) FR2350100A1 (fr)
GB (1) GB1529782A (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0099148A1 (fr) * 1982-06-29 1984-01-25 Gist-Brocades N.V. Dérivés de pipérazine, leurs procédés de préparation en compositions pharmaceutiques les contenant
EP0259227B1 (fr) * 1986-09-05 1991-12-27 Société anonyme: LES LABORATOIRES MERAM Dérivés de la benzhydryloxyéthyl-pipéridine, procédé d'obtention et compositions pharmaceutiques les contenant
EP0254627B1 (fr) * 1986-07-10 1992-06-17 Société anonyme: LES LABORATOIRES MERAM Dérivés de la benzhydryloxyéthylpipérazine, procédés d'obtention et compositions pharmaceutiques les contenant

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE10193T1 (de) * 1980-06-16 1984-11-15 Ab Ferrosan Diphenylbutyl-1-acylpiperazine.
JPS61207380A (ja) * 1985-03-11 1986-09-13 Taiyo Yakuhin Kogyo Kk モベンゾキサミンの経口製剤
US5276035A (en) * 1990-07-26 1994-01-04 Novo Nordisk A/S 1,4-disubstituted piperazines
DK178490D0 (da) * 1990-07-26 1990-07-26 Novo Nordisk As 1,4-disubstituerede piperaziner
JPH10504324A (ja) * 1995-06-07 1998-04-28 デイド、ケミストリー、システムズ、インコーポレイテッド 薬物の免疫原その他の接合体の製造
EP0937053A1 (fr) * 1996-10-31 1999-08-25 THE UNITED STATES OF AMERICA, as represented by the Secretary of the Department of Health and Human Services Derives a liberation prolongee d'analogues hydroxyles de 1- 2 bis(aryl)methoxy]ethyl]-piperazines et -homopiperazines substituees et leur utilisation comme antagonistes non competitifs du recaptage de la dopamine

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0099148A1 (fr) * 1982-06-29 1984-01-25 Gist-Brocades N.V. Dérivés de pipérazine, leurs procédés de préparation en compositions pharmaceutiques les contenant
EP0254627B1 (fr) * 1986-07-10 1992-06-17 Société anonyme: LES LABORATOIRES MERAM Dérivés de la benzhydryloxyéthylpipérazine, procédés d'obtention et compositions pharmaceutiques les contenant
EP0259227B1 (fr) * 1986-09-05 1991-12-27 Société anonyme: LES LABORATOIRES MERAM Dérivés de la benzhydryloxyéthyl-pipéridine, procédé d'obtention et compositions pharmaceutiques les contenant

Also Published As

Publication number Publication date
DE2719246A1 (de) 1977-11-10
GB1529782A (en) 1978-10-25
ES456988A1 (es) 1978-02-16
FR2350100B1 (fr) 1979-04-27
DE2719246C2 (de) 1984-11-08

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Legal Events

Date Code Title Description
TP Transmission of property
TP Transmission of property
ST Notification of lapse