GB1509074A - Cephalosporin derivatives - Google Patents
Cephalosporin derivativesInfo
- Publication number
- GB1509074A GB1509074A GB1302875A GB1302875A GB1509074A GB 1509074 A GB1509074 A GB 1509074A GB 1302875 A GB1302875 A GB 1302875A GB 1302875 A GB1302875 A GB 1302875A GB 1509074 A GB1509074 A GB 1509074A
- Authority
- GB
- United Kingdom
- Prior art keywords
- group
- ring
- compounds
- nitrogen atoms
- hydrogen atom
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229930186147 Cephalosporin Natural products 0.000 title 1
- 229940124587 cephalosporin Drugs 0.000 title 1
- 150000001780 cephalosporins Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 3
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- 125000004043 oxo group Chemical group O=* 0.000 abstract 2
- 229910052717 sulfur Inorganic materials 0.000 abstract 2
- 125000004434 sulfur atom Chemical group 0.000 abstract 2
- QMDFJHAAWUGVKQ-UHFFFAOYSA-N 2h-thiopyran Chemical group C1SC=CC=C1 QMDFJHAAWUGVKQ-UHFFFAOYSA-N 0.000 abstract 1
- GNSPINPIWPZMKW-UHFFFAOYSA-N [1,2,4]triazolo[3,4-b][1,3,4]thiadiazole Chemical group C1=NN=C2SC=NN21 GNSPINPIWPZMKW-UHFFFAOYSA-N 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- YGBFLZPYDUKSPT-MRVPVSSYSA-N cephalosporanic acid Chemical class S1CC(COC(=O)C)=C(C(O)=O)N2C(=O)C[C@H]21 YGBFLZPYDUKSPT-MRVPVSSYSA-N 0.000 abstract 1
- -1 heterocyclic thiol Chemical class 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 125000000843 phenylene group Chemical group C1(=C(C=CC=C1)*)* 0.000 abstract 1
- ILVXOBCQQYKLDS-UHFFFAOYSA-N pyridine N-oxide Chemical group [O-][N+]1=CC=CC=C1 ILVXOBCQQYKLDS-UHFFFAOYSA-N 0.000 abstract 1
- 125000002943 quinolinyl group Chemical group N1=C(C=CC2=CC=CC=C12)* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000000020 sulfo group Chemical group O=S(=O)([*])O[H] 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/36—Methylene radicals, substituted by sulfur atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP49038545A JPS5953276B2 (ja) | 1974-04-05 | 1974-04-05 | 新セフアロスポリン誘導体の製造方法 |
| JP4188474A JPS50140480A (enrdf_load_stackoverflow) | 1974-04-15 | 1974-04-15 | |
| JP6312474A JPS50154282A (enrdf_load_stackoverflow) | 1974-06-04 | 1974-06-04 | |
| JP6477474A JPS604191B2 (ja) | 1974-06-07 | 1974-06-07 | セフアロスポラン酸新誘導体の合成方法 |
| JP49116976A JPS5143785A (en) | 1974-10-11 | 1974-10-11 | Shinsefuarosuhorinkanrenkagobutsuno goseiho |
| JP11963874A JPS5148686A (ja) | 1974-10-17 | 1974-10-17 | Shinsefuarosuhorinkanrenkagobutsuno goseihoho |
| JP50013200A JPS5188988A (enrdf_load_stackoverflow) | 1975-01-31 | 1975-01-31 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1509074A true GB1509074A (en) | 1978-04-26 |
Family
ID=27563645
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1302875A Expired GB1509074A (en) | 1974-04-05 | 1975-03-27 | Cephalosporin derivatives |
Country Status (4)
| Country | Link |
|---|---|
| DE (1) | DE2514322A1 (enrdf_load_stackoverflow) |
| DK (1) | DK143875A (enrdf_load_stackoverflow) |
| FR (1) | FR2266507B1 (enrdf_load_stackoverflow) |
| GB (1) | GB1509074A (enrdf_load_stackoverflow) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114671892A (zh) * | 2022-04-24 | 2022-06-28 | 江苏海洋大学 | 含7-氨基头孢烷酸的1,3,4-噻二唑衍生物及制法与用途 |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1074784A (en) * | 1974-09-06 | 1980-04-01 | Sumitomo Chemical Company | N-ACYLAMINO-.alpha.-ARYLACETAMIDO CEPHALOSPORINS |
| US4286089A (en) | 1974-12-27 | 1981-08-25 | Smithkline Corporation | 7-Acyl-3-(substituted tetrazolyl thiomethyl)cephalosporins |
| US4093723A (en) | 1976-05-19 | 1978-06-06 | Smithkline Corporation | 7-Acyl-3-(sulfonic acid and sulfamoyl substituted tetrazolyl thiomethyl) cephalosporins |
| US4041162A (en) | 1976-03-11 | 1977-08-09 | Smithkline Corporation | 7-Acyl-3-(sulfoalkyl substituted oxadiazolylthiomethyl) cephalosporins |
| US4101656A (en) | 1976-07-12 | 1978-07-18 | Smithkline Corporation | 7β-Acylamino-3-(alkanesulfonamidoalkyl substituted tetrazolylthiomethyl) cephalosporins, antibacterial compositions containing them and methods of treating bacterial infections with them |
| JPS545974A (en) * | 1977-06-16 | 1979-01-17 | Ajinomoto Co Inc | Imidazoledicaroboxylic acid derivatives |
| US4117124A (en) * | 1977-06-30 | 1978-09-26 | Smithkline Corporation | 7-Acylamino-3-[[3-(carboxymethyl)thio-1H-1,2,4-triazol-5-yl]thiomethyl]-3-cephem-4-carboxylic acids |
| JPS55129287A (en) * | 1979-03-27 | 1980-10-06 | Ajinomoto Co Inc | Imidazole-dicarboxylic acid derivative |
| US4576937A (en) * | 1984-02-29 | 1986-03-18 | Smithkline Beckman Corporation | 7-D-Mandelamido-3(1-sulfomethyltetrazol-5-yl)thiomethyl-3-cephem-4-carboxylic acid monosodium salt |
| US5273973A (en) * | 1988-10-24 | 1993-12-28 | Norwich Eaton Pharmaceuticals, Inc. | Antimicrobial quinolonyl esters |
| US5180719A (en) * | 1988-10-24 | 1993-01-19 | Norwich Eaton Pharmaceuticals, Inc. | Antimicrobial quinolonyl lactam esters |
| CA2001203C (en) * | 1988-10-24 | 2001-02-13 | Thomas P. Demuth, Jr. | Novel antimicrobial dithiocarbamoyl quinolones |
| US5491139A (en) * | 1988-10-24 | 1996-02-13 | The Procter & Gamble Company | Antimicrobial quinolonyl lactams |
| US5328908A (en) * | 1988-10-24 | 1994-07-12 | Procter & Gamble Pharmaceuticals, Inc. | Antimicrobial quinolone thioureas |
| EP0366189A3 (en) * | 1988-10-24 | 1992-01-02 | Norwich Eaton Pharmaceuticals, Inc. | Novel antimicrobial lactam-quinolones |
| ES2147721T3 (es) * | 1990-04-18 | 2000-10-01 | Procter & Gamble Pharma | Quinolonil lactamas antimicrobianas. |
-
1975
- 1975-03-27 GB GB1302875A patent/GB1509074A/en not_active Expired
- 1975-04-02 DE DE19752514322 patent/DE2514322A1/de active Pending
- 1975-04-03 FR FR7510474A patent/FR2266507B1/fr not_active Expired
- 1975-04-04 DK DK143875A patent/DK143875A/da not_active IP Right Cessation
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114671892A (zh) * | 2022-04-24 | 2022-06-28 | 江苏海洋大学 | 含7-氨基头孢烷酸的1,3,4-噻二唑衍生物及制法与用途 |
| CN114671892B (zh) * | 2022-04-24 | 2023-04-11 | 江苏海洋大学 | 含7-氨基头孢烷酸的1,3,4-噻二唑衍生物及制法与用途 |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2266507A1 (enrdf_load_stackoverflow) | 1975-10-31 |
| DE2514322A1 (de) | 1975-10-09 |
| FR2266507B1 (enrdf_load_stackoverflow) | 1978-11-10 |
| DK143875A (enrdf_load_stackoverflow) | 1975-10-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |