GB1467763A - 2-substituted thio-1,4-benzodiazepine derivatives - Google Patents
2-substituted thio-1,4-benzodiazepine derivativesInfo
- Publication number
- GB1467763A GB1467763A GB1151875A GB1151875A GB1467763A GB 1467763 A GB1467763 A GB 1467763A GB 1151875 A GB1151875 A GB 1151875A GB 1151875 A GB1151875 A GB 1151875A GB 1467763 A GB1467763 A GB 1467763A
- Authority
- GB
- United Kingdom
- Prior art keywords
- march
- alkyl
- compounds
- benzodiazepine derivatives
- substituted thio
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
- C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
- C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
- C07D243/22—Sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Anesthesiology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Abstract
1467763 Benzodiazepines FUJISAWA PHARMACEUTICAL CO Ltd 19 March 1975 [20 March 1974] 11518/75 Heading C2C Compounds of the general formula (R 1 , 2 =H, halogen, NO 2 , NH 2 , CN, alkyl, haloalkyl, alkoxy, alkylthio, alkanesulphinyl, alkanesulphonyl, alkanoylamino, dialkylamino; R 3 =alkylene; R 4 , 5 =H, alkyl or NR 4 R 5 =ring which may contain an oxygen atom or a second nitrogen atom and/or may be substituted) and their salts are prepared by reacting the corresponding 2-thione with R 4 R 5 NR 3 )X (X = acid residue), optionally followed by salt formation. These compounds are psychotropic agents, and may be administered in the form of pharmaceutical preparations containing them in association with a carrier.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP49031905A JPS5919099B2 (en) | 1974-03-20 | 1974-03-20 | Method for producing 2-substituted thio-1,4-benzodiazepine derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1467763A true GB1467763A (en) | 1977-03-23 |
Family
ID=12344003
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB1151875A Expired GB1467763A (en) | 1974-03-20 | 1975-03-19 | 2-substituted thio-1,4-benzodiazepine derivatives |
Country Status (15)
Country | Link |
---|---|
JP (1) | JPS5919099B2 (en) |
AU (1) | AU7929875A (en) |
BE (1) | BE826817A (en) |
CA (1) | CA1064029A (en) |
DE (1) | DE2511898A1 (en) |
DK (1) | DK114175A (en) |
ES (1) | ES435812A1 (en) |
FI (1) | FI750816A (en) |
FR (1) | FR2264545B1 (en) |
GB (1) | GB1467763A (en) |
HU (1) | HU170141B (en) |
NL (1) | NL7503269A (en) |
NO (1) | NO750943L (en) |
SE (1) | SE7503164L (en) |
ZA (1) | ZA751715B (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4094870A (en) * | 1974-03-20 | 1978-06-13 | Fujisawa Pharmaceutical Co., Ltd. | 2-Substituted thio-1,4-benzodiazepine derivatives |
-
1974
- 1974-03-20 JP JP49031905A patent/JPS5919099B2/en not_active Expired
-
1975
- 1975-03-18 HU HUFU333A patent/HU170141B/hu unknown
- 1975-03-18 BE BE154448A patent/BE826817A/en unknown
- 1975-03-19 DK DK114175A patent/DK114175A/da unknown
- 1975-03-19 AU AU79298/75A patent/AU7929875A/en not_active Expired
- 1975-03-19 CA CA222,537A patent/CA1064029A/en not_active Expired
- 1975-03-19 NO NO750943A patent/NO750943L/no unknown
- 1975-03-19 ZA ZA00751715A patent/ZA751715B/en unknown
- 1975-03-19 FI FI750816A patent/FI750816A/fi not_active Application Discontinuation
- 1975-03-19 SE SE7503164A patent/SE7503164L/xx unknown
- 1975-03-19 FR FR7508599A patent/FR2264545B1/fr not_active Expired
- 1975-03-19 GB GB1151875A patent/GB1467763A/en not_active Expired
- 1975-03-19 NL NL7503269A patent/NL7503269A/en unknown
- 1975-03-19 DE DE19752511898 patent/DE2511898A1/en not_active Withdrawn
- 1975-03-20 ES ES435812A patent/ES435812A1/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
ZA751715B (en) | 1976-02-25 |
BE826817A (en) | 1975-09-18 |
NO750943L (en) | 1975-09-23 |
SE7503164L (en) | 1975-09-22 |
DE2511898A1 (en) | 1975-09-25 |
FR2264545B1 (en) | 1978-08-04 |
ES435812A1 (en) | 1976-12-01 |
FI750816A (en) | 1975-09-21 |
JPS5919099B2 (en) | 1984-05-02 |
CA1064029A (en) | 1979-10-09 |
AU7929875A (en) | 1976-09-23 |
NL7503269A (en) | 1975-09-23 |
HU170141B (en) | 1977-04-28 |
DK114175A (en) | 1975-09-21 |
JPS50131980A (en) | 1975-10-18 |
FR2264545A1 (en) | 1975-10-17 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed [section 19, patents act 1949] | ||
PCNP | Patent ceased through non-payment of renewal fee |