GB1467763A - 2-substituted thio-1,4-benzodiazepine derivatives - Google Patents

2-substituted thio-1,4-benzodiazepine derivatives

Info

Publication number
GB1467763A
GB1467763A GB1151875A GB1151875A GB1467763A GB 1467763 A GB1467763 A GB 1467763A GB 1151875 A GB1151875 A GB 1151875A GB 1151875 A GB1151875 A GB 1151875A GB 1467763 A GB1467763 A GB 1467763A
Authority
GB
United Kingdom
Prior art keywords
march
alkyl
compounds
benzodiazepine derivatives
substituted thio
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1151875A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujisawa Pharmaceutical Co Ltd
Original Assignee
Fujisawa Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujisawa Pharmaceutical Co Ltd filed Critical Fujisawa Pharmaceutical Co Ltd
Publication of GB1467763A publication Critical patent/GB1467763A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/22Sulfur atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives

Abstract

1467763 Benzodiazepines FUJISAWA PHARMACEUTICAL CO Ltd 19 March 1975 [20 March 1974] 11518/75 Heading C2C Compounds of the general formula (R 1 , 2 =H, halogen, NO 2 , NH 2 , CN, alkyl, haloalkyl, alkoxy, alkylthio, alkanesulphinyl, alkanesulphonyl, alkanoylamino, dialkylamino; R 3 =alkylene; R 4 , 5 =H, alkyl or NR 4 R 5 =ring which may contain an oxygen atom or a second nitrogen atom and/or may be substituted) and their salts are prepared by reacting the corresponding 2-thione with R 4 R 5 NR 3 )X (X = acid residue), optionally followed by salt formation. These compounds are psychotropic agents, and may be administered in the form of pharmaceutical preparations containing them in association with a carrier.
GB1151875A 1974-03-20 1975-03-19 2-substituted thio-1,4-benzodiazepine derivatives Expired GB1467763A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP49031905A JPS5919099B2 (en) 1974-03-20 1974-03-20 Method for producing 2-substituted thio-1,4-benzodiazepine derivatives

Publications (1)

Publication Number Publication Date
GB1467763A true GB1467763A (en) 1977-03-23

Family

ID=12344003

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1151875A Expired GB1467763A (en) 1974-03-20 1975-03-19 2-substituted thio-1,4-benzodiazepine derivatives

Country Status (15)

Country Link
JP (1) JPS5919099B2 (en)
AU (1) AU7929875A (en)
BE (1) BE826817A (en)
CA (1) CA1064029A (en)
DE (1) DE2511898A1 (en)
DK (1) DK114175A (en)
ES (1) ES435812A1 (en)
FI (1) FI750816A (en)
FR (1) FR2264545B1 (en)
GB (1) GB1467763A (en)
HU (1) HU170141B (en)
NL (1) NL7503269A (en)
NO (1) NO750943L (en)
SE (1) SE7503164L (en)
ZA (1) ZA751715B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4094870A (en) * 1974-03-20 1978-06-13 Fujisawa Pharmaceutical Co., Ltd. 2-Substituted thio-1,4-benzodiazepine derivatives

Also Published As

Publication number Publication date
SE7503164L (en) 1975-09-22
HU170141B (en) 1977-04-28
JPS5919099B2 (en) 1984-05-02
FR2264545A1 (en) 1975-10-17
DK114175A (en) 1975-09-21
DE2511898A1 (en) 1975-09-25
ES435812A1 (en) 1976-12-01
FI750816A (en) 1975-09-21
BE826817A (en) 1975-09-18
ZA751715B (en) 1976-02-25
JPS50131980A (en) 1975-10-18
NL7503269A (en) 1975-09-23
FR2264545B1 (en) 1978-08-04
NO750943L (en) 1975-09-23
CA1064029A (en) 1979-10-09
AU7929875A (en) 1976-09-23

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee