ES8801292A1 - Procedimiento para la obtencion de compuestos de heterociclil-penem - Google Patents

Procedimiento para la obtencion de compuestos de heterociclil-penem

Info

Publication number
ES8801292A1
ES8801292A1 ES553986A ES553986A ES8801292A1 ES 8801292 A1 ES8801292 A1 ES 8801292A1 ES 553986 A ES553986 A ES 553986A ES 553986 A ES553986 A ES 553986A ES 8801292 A1 ES8801292 A1 ES 8801292A1
Authority
ES
Spain
Prior art keywords
ring
compounds
penem
formula
lower alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES553986A
Other languages
English (en)
Other versions
ES553986A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of ES8801292A1 publication Critical patent/ES8801292A1/es
Publication of ES553986A0 publication Critical patent/ES553986A0/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)

Abstract

PROCEDIMIENTO PARA OBTENER COMPUESTOS DE HETEROCICLIL-PENEM. COMPRENDE: A) DISOLVER A UN COMPUESTO DE FORMULA (II) EN DIOXANO; Y B( CALENTAR LA DISOLUCION ENTRE 30J Y 160JC, PARA CERRAR EL ANILLO DE (II) Y OBTENER UN COMPUESTO DE FORMULA (I) Y SUS SALES FARMACEUTICAMENTE ACEPTABLES. SIENDO: R1, ALQUILO INFERIOR SUSTITUIDO POR HIDROXI; R2, UN RESTO HETEROARILO DE 5 MIEMBROS MONOCICLICO; R3, CARBOXILO; XB, FOSFONIO TRES VECES SUSTITUIDO; R''3, R3; Y Z, O O S. SE UTILIZAN PARA COMBATIR INFECCIONES PRODUCIDAS POR BACTERIAS GRAM-(B) Y GRAM-(C).
ES553986A 1985-04-17 1986-04-15 Procedimiento para la obtencion de compuestos de heterociclil-penem Expired ES8801292A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH163585 1985-04-17

Publications (2)

Publication Number Publication Date
ES8801292A1 true ES8801292A1 (es) 1987-12-16
ES553986A0 ES553986A0 (es) 1987-12-16

Family

ID=4215062

Family Applications (1)

Application Number Title Priority Date Filing Date
ES553986A Expired ES8801292A1 (es) 1985-04-17 1986-04-15 Procedimiento para la obtencion de compuestos de heterociclil-penem

Country Status (6)

Country Link
EP (1) EP0199675A1 (es)
JP (1) JPS61243088A (es)
KR (1) KR860008186A (es)
AU (1) AU5618986A (es)
DK (1) DK172486A (es)
ES (1) ES8801292A1 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4826832A (en) * 1986-05-06 1989-05-02 Ciba-Geigy Corporation Penen compounds
CA2019260C (en) * 1989-06-22 1999-06-29 Hirokazu Ochiai Penam derivatives and salts thereof, processes for producing the same and antibacterial agent comprising the same
JP2973126B2 (ja) * 1989-06-22 1999-11-08 富山化学工業株式会社 新規なペナム誘導体およびその塩
EP0597401A3 (en) * 1992-11-11 1995-07-26 Takeda Chemical Industries Ltd Preparation of penemes.
KR0168979B1 (ko) * 1995-07-12 1999-01-15 김종인 티아졸릴 트리아졸로티아졸 유도체
CN113943263A (zh) * 2021-11-17 2022-01-18 凯美克(上海)医药科技有限公司 一种2-(氨基甲基)-1,3-噻唑-5-羧酸甲酯的合成方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4168314A (en) * 1977-11-17 1979-09-18 Merck & Co., Inc. 6-(1'-Hydroxyethyl)-2-aminoethylthio-pen-2-em-3-carboxylic acid
EP0003960B1 (de) * 1978-02-02 1983-06-29 Ciba-Geigy Ag 6-Substituierte Thia-Azaverbindungen, ihre Herstellung und diese enthaltende pharmazeutische Präparate
EP0109362A1 (de) * 1982-11-16 1984-05-23 Ciba-Geigy Ag Heterocyclylverbindungen, Verfahren zu ihrer Herstellung, pharmazeutische Präparate, welche diese Verbindungen enthalten, und Verwendung von letzteren

Also Published As

Publication number Publication date
EP0199675A1 (de) 1986-10-29
KR860008186A (ko) 1986-11-12
DK172486D0 (da) 1986-04-16
JPS61243088A (ja) 1986-10-29
AU5618986A (en) 1986-10-23
DK172486A (da) 1986-10-18
ES553986A0 (es) 1987-12-16

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