ES8507545A1 - Un procedimiento para la preparacion de derivados de 1-normon-2-ilo. - Google Patents

Un procedimiento para la preparacion de derivados de 1-normon-2-ilo.

Info

Publication number
ES8507545A1
ES8507545A1 ES530030A ES530030A ES8507545A1 ES 8507545 A1 ES8507545 A1 ES 8507545A1 ES 530030 A ES530030 A ES 530030A ES 530030 A ES530030 A ES 530030A ES 8507545 A1 ES8507545 A1 ES 8507545A1
Authority
ES
Spain
Prior art keywords
carbon
image
nitrogen
atoms
atom
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES530030A
Other languages
English (en)
Other versions
ES530030A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Publication of ES8507545A1 publication Critical patent/ES8507545A1/es
Publication of ES530030A0 publication Critical patent/ES530030A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/14—Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE DERIVADOS DE 1-NORMON-2-ILO, DE FORMULA GENERAL (I).CONSISTE EN HACER REACCIONAR UN COMPUESTO DE FORMULA GENERAL (II), EN LA QUE Z1, Z2 Y Z3 SON IGUALES O DIFERENTES Y CADA UNO DE ELLOS ES HIDROGENO O UN GRUPO PROTECTOR DE HIDROXI, CON UN COMPUESTO DE FORMULA GENERAL (III), EN LA QUE MB ES UN CATION METALICO, PREFERIBLEMENTE UN CATION DE METAL ALCALINO; Y R3 ES UN GRUPO ESTABILIZANTE DE ANIONES QUE SE ELIMINA ESPONTANEAMENTE CON UN GRUPO BBB-HIDROXILO, PARA PRODUCIR UNA OLEFINA.DE APLICACION EN MEDICINA Y VETERINARIA POR SU ACTIVIDAD ANTIBACTERIANA Y ANTIMICOPLASMICA.
ES530030A 1983-02-25 1984-02-24 Un procedimiento para la preparacion de derivados de 1-normon-2-ilo. Granted ES530030A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB838305316A GB8305316D0 (en) 1983-02-25 1983-02-25 Compounds

Publications (2)

Publication Number Publication Date
ES8507545A1 true ES8507545A1 (es) 1985-09-01
ES530030A0 ES530030A0 (es) 1985-09-01

Family

ID=10538629

Family Applications (4)

Application Number Title Priority Date Filing Date
ES530030A Granted ES530030A0 (es) 1983-02-25 1984-02-24 Un procedimiento para la preparacion de derivados de 1-normon-2-ilo.
ES538699A Expired ES8601981A1 (es) 1983-02-25 1984-12-17 Un procedimiento para la preparacion de derivados de 1-normon-2-ilo
ES538698A Expired ES8601975A1 (es) 1983-02-25 1984-12-17 Un procedimiento para la preparacion de derivados de 1-normon-2-ilo
ES538697A Granted ES538697A0 (es) 1983-02-25 1984-12-17 Un procedimiento para la preparacion de derivados de 1-normon-2-ilo

Family Applications After (3)

Application Number Title Priority Date Filing Date
ES538699A Expired ES8601981A1 (es) 1983-02-25 1984-12-17 Un procedimiento para la preparacion de derivados de 1-normon-2-ilo
ES538698A Expired ES8601975A1 (es) 1983-02-25 1984-12-17 Un procedimiento para la preparacion de derivados de 1-normon-2-ilo
ES538697A Granted ES538697A0 (es) 1983-02-25 1984-12-17 Un procedimiento para la preparacion de derivados de 1-normon-2-ilo

Country Status (12)

Country Link
US (1) US4861788A (es)
EP (1) EP0123378B1 (es)
JP (1) JPS59196889A (es)
AU (1) AU579311B2 (es)
CA (1) CA1240318A (es)
DE (1) DE3479657D1 (es)
DK (1) DK96184A (es)
ES (4) ES530030A0 (es)
GB (1) GB8305316D0 (es)
GR (1) GR79823B (es)
NZ (1) NZ207261A (es)
ZA (1) ZA841366B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8815626D0 (en) * 1988-06-30 1988-08-03 Beecham Group Plc Novel compounds
IL94051A0 (en) * 1989-04-12 1991-01-31 Beecham Group Plc 1-normon-2-yl-heterocycles,process for their preparation and pharmaceutical compositions containing them
GB8928839D0 (en) * 1989-12-21 1990-02-28 Beecham Group Plc Novel compounds
GB9325832D0 (en) * 1993-12-17 1994-02-23 Smithkline Beecham Plc Novel compounds
US6951946B2 (en) * 2002-03-19 2005-10-04 Lexicon Pharmaceuticals, Inc. Large scale synthesis of 1,2,4- and 1,3,4-oxadiazole carboxylates

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2860726D1 (en) * 1977-11-05 1981-08-27 Beecham Group Plc Antibacterially active amides, process for their preparation and pharmaceutical compositions containing said amides
EP0045150A1 (en) * 1980-07-24 1982-02-03 Beecham Group Plc Antibacterial compounds, processes for their preparation and composititions containing them
PT73431B (en) * 1980-08-02 1982-10-08 Beecham Group Plc Antibacterial compounds processes for their preparation and compositions containing them
US4436751A (en) * 1980-12-31 1984-03-13 Beecham Group Limited Nitrobenzyl monates antibacterial compounds
EP0087953B1 (en) * 1982-02-27 1988-04-27 Beecham Group Plc Antibacterial 1-normon-2-yl-heterocyclic compounds

Also Published As

Publication number Publication date
US4861788A (en) 1989-08-29
ES538698A0 (es) 1985-11-01
DK96184A (da) 1984-08-26
ES538699A0 (es) 1985-11-01
EP0123378A2 (en) 1984-10-31
DE3479657D1 (en) 1989-10-12
NZ207261A (en) 1987-10-30
DK96184D0 (da) 1984-02-23
ES8601980A1 (es) 1985-11-01
JPH0534357B2 (es) 1993-05-21
ZA841366B (en) 1985-01-30
CA1240318A (en) 1988-08-09
EP0123378A3 (en) 1985-09-18
ES538697A0 (es) 1985-11-01
GR79823B (es) 1984-10-31
GB8305316D0 (en) 1983-03-30
ES530030A0 (es) 1985-09-01
AU2486084A (en) 1984-08-30
JPS59196889A (ja) 1984-11-08
ES8601981A1 (es) 1985-11-01
ES8601975A1 (es) 1985-11-01
AU579311B2 (en) 1988-11-24
EP0123378B1 (en) 1989-09-06

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Legal Events

Date Code Title Description
MM4A Patent lapsed

Effective date: 19960506