GB1493969A - Physiologically active tetrapeptides and their n-acyl derivatives and processes for producing the same - Google Patents
Physiologically active tetrapeptides and their n-acyl derivatives and processes for producing the sameInfo
- Publication number
- GB1493969A GB1493969A GB681975A GB681975A GB1493969A GB 1493969 A GB1493969 A GB 1493969A GB 681975 A GB681975 A GB 681975A GB 681975 A GB681975 A GB 681975A GB 1493969 A GB1493969 A GB 1493969A
- Authority
- GB
- United Kingdom
- Prior art keywords
- val
- isovaleryl
- ala
- feb
- dec
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- -1 isovaleryl Chemical group 0.000 abstract 6
- DFVFTMTWCUHJBL-UHFFFAOYSA-N 4-azaniumyl-3-hydroxy-6-methylheptanoate Chemical compound CC(C)CC(N)C(O)CC(O)=O DFVFTMTWCUHJBL-UHFFFAOYSA-N 0.000 abstract 2
- 102000004190 Enzymes Human genes 0.000 abstract 2
- 108090000790 Enzymes Proteins 0.000 abstract 2
- KZSNJWFQEVHDMF-BYPYZUCNSA-N L-valine Chemical compound CC(C)[C@H](N)C(O)=O KZSNJWFQEVHDMF-BYPYZUCNSA-N 0.000 abstract 2
- 125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 244000005700 microbiome Species 0.000 abstract 2
- 241000589212 Acetobacter pasteurianus Species 0.000 abstract 1
- 241000607528 Aeromonas hydrophila Species 0.000 abstract 1
- 241000589155 Agrobacterium tumefaciens Species 0.000 abstract 1
- 241000186063 Arthrobacter Species 0.000 abstract 1
- 241000193752 Bacillus circulans Species 0.000 abstract 1
- 241000194107 Bacillus megaterium Species 0.000 abstract 1
- 235000014469 Bacillus subtilis Nutrition 0.000 abstract 1
- 241001274890 Boeremia exigua Species 0.000 abstract 1
- 241000186320 Cellulomonas fimi Species 0.000 abstract 1
- 240000001817 Cereus hexagonus Species 0.000 abstract 1
- 241000588919 Citrobacter freundii Species 0.000 abstract 1
- 241000193171 Clostridium butyricum Species 0.000 abstract 1
- 241000222199 Colletotrichum Species 0.000 abstract 1
- 241000186145 Corynebacterium ammoniagenes Species 0.000 abstract 1
- 241000194032 Enterococcus faecalis Species 0.000 abstract 1
- 241000588724 Escherichia coli Species 0.000 abstract 1
- 241001149959 Fusarium sp. Species 0.000 abstract 1
- 241000588915 Klebsiella aerogenes Species 0.000 abstract 1
- 241000191948 Kocuria rosea Species 0.000 abstract 1
- 240000001929 Lactobacillus brevis Species 0.000 abstract 1
- 235000013957 Lactobacillus brevis Nutrition 0.000 abstract 1
- 241000192130 Leuconostoc mesenteroides Species 0.000 abstract 1
- 241000193386 Lysinibacillus sphaericus Species 0.000 abstract 1
- 241001495426 Macrophomina phaseolina Species 0.000 abstract 1
- 241001467566 Microbacterium lacticum Species 0.000 abstract 1
- 241000191938 Micrococcus luteus Species 0.000 abstract 1
- 241000242366 Microcyclus Species 0.000 abstract 1
- 241000186334 Propionibacterium freudenreichii subsp. shermanii Species 0.000 abstract 1
- 241000586779 Protaminobacter Species 0.000 abstract 1
- 241000589516 Pseudomonas Species 0.000 abstract 1
- 241001361634 Rhizoctonia Species 0.000 abstract 1
- 241000191963 Staphylococcus epidermidis Species 0.000 abstract 1
- 241000266363 Stemphylium sarciniforme Species 0.000 abstract 1
- 241000589636 Xanthomonas campestris Species 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000003236 benzoyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C(*)=O 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 125000001721 carboxyacetyl group Chemical group 0.000 abstract 1
- 238000000354 decomposition reaction Methods 0.000 abstract 1
- 229940092559 enterobacter aerogenes Drugs 0.000 abstract 1
- 229910052736 halogen Chemical group 0.000 abstract 1
- 150000002367 halogens Chemical group 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 125000003431 oxalo group Chemical group 0.000 abstract 1
- 125000001312 palmitoyl group Chemical group O=C([*])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 239000000758 substrate Substances 0.000 abstract 1
- 229960004295 valine Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0205—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)3-C(=0)-, e.g. statine or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/58—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from fungi
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
- C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Crystallography & Structural Chemistry (AREA)
- Biophysics (AREA)
- Mycology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2395374A JPS5339513B2 (enrdf_load_stackoverflow) | 1974-02-28 | 1974-02-28 | |
| JP2884974A JPS5533880B2 (enrdf_load_stackoverflow) | 1974-03-12 | 1974-03-12 | |
| JP49040696A JPS5233094B2 (enrdf_load_stackoverflow) | 1974-04-10 | 1974-04-10 | |
| JP14520874A JPS537516B2 (enrdf_load_stackoverflow) | 1974-12-17 | 1974-12-17 | |
| JP14647474A JPS5173187A (en) | 1974-12-19 | 1974-12-19 | nn ashirupeputaidoruibunkaikosono seizoho |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1493969A true GB1493969A (en) | 1977-12-07 |
Family
ID=27520592
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB681975A Expired GB1493969A (en) | 1974-02-28 | 1975-02-18 | Physiologically active tetrapeptides and their n-acyl derivatives and processes for producing the same |
Country Status (4)
| Country | Link |
|---|---|
| CA (1) | CA1040123A (enrdf_load_stackoverflow) |
| DE (1) | DE2506601C3 (enrdf_load_stackoverflow) |
| FR (1) | FR2262532B1 (enrdf_load_stackoverflow) |
| GB (1) | GB1493969A (enrdf_load_stackoverflow) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5424845A (en) * | 1977-07-22 | 1979-02-24 | Microbial Chem Res Found | Novel bio-active peptide and its derivative |
| US4384994A (en) * | 1981-10-08 | 1983-05-24 | Merck & Co., Inc. | Renin inhibitory peptides |
| CA1258748A (en) * | 1981-10-08 | 1989-08-22 | Daniel F. Veber | Renin inhibitory peptides |
| CA1245217A (en) * | 1981-12-10 | 1988-11-22 | Joshua S. Boger | Renin inhibitory peptides having phe su13 xx deletion |
| FR2531951A1 (fr) * | 1982-08-17 | 1984-02-24 | Sanofi Sa | Derives peptidiques inhibiteurs de proteases acides, procede pour leur preparation et medicaments qui en contiennent |
-
1975
- 1975-02-17 DE DE19752506601 patent/DE2506601C3/de not_active Expired
- 1975-02-18 GB GB681975A patent/GB1493969A/en not_active Expired
- 1975-02-25 FR FR7505849A patent/FR2262532B1/fr not_active Expired
- 1975-02-27 CA CA221,066A patent/CA1040123A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| CA1040123A (en) | 1978-10-10 |
| DE2506601B2 (de) | 1980-04-24 |
| FR2262532B1 (enrdf_load_stackoverflow) | 1978-12-22 |
| FR2262532A1 (enrdf_load_stackoverflow) | 1975-09-26 |
| DE2506601A1 (de) | 1975-09-04 |
| DE2506601C3 (de) | 1980-12-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |