GB1492140A - Benzylpyrimidine derivatives - Google Patents

Benzylpyrimidine derivatives

Info

Publication number
GB1492140A
GB1492140A GB52604/75A GB5260475A GB1492140A GB 1492140 A GB1492140 A GB 1492140A GB 52604/75 A GB52604/75 A GB 52604/75A GB 5260475 A GB5260475 A GB 5260475A GB 1492140 A GB1492140 A GB 1492140A
Authority
GB
United Kingdom
Prior art keywords
amino
groups
compounds
pyrrolidino
piperidino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB52604/75A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of GB1492140A publication Critical patent/GB1492140A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/325Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/325Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
    • C07D207/327Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56Nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48Two nitrogen atoms
    • C07D239/49Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cosmetics (AREA)
GB52604/75A 1974-12-24 1975-12-23 Benzylpyrimidine derivatives Expired GB1492140A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1728774A CH605828A5 (enrdf_load_stackoverflow) 1974-12-24 1974-12-24

Publications (1)

Publication Number Publication Date
GB1492140A true GB1492140A (en) 1977-11-16

Family

ID=4424233

Family Applications (1)

Application Number Title Priority Date Filing Date
GB52604/75A Expired GB1492140A (en) 1974-12-24 1975-12-23 Benzylpyrimidine derivatives

Country Status (25)

Country Link
JP (1) JPS5191273A (enrdf_load_stackoverflow)
AT (1) AT344704B (enrdf_load_stackoverflow)
AU (1) AU500102B2 (enrdf_load_stackoverflow)
BE (1) BE836996A (enrdf_load_stackoverflow)
BR (1) BR7508534A (enrdf_load_stackoverflow)
CA (1) CA1059127A (enrdf_load_stackoverflow)
CH (2) CH605828A5 (enrdf_load_stackoverflow)
CU (1) CU34406A (enrdf_load_stackoverflow)
DD (1) DD123603A5 (enrdf_load_stackoverflow)
DE (1) DE2558150A1 (enrdf_load_stackoverflow)
DK (1) DK137797B (enrdf_load_stackoverflow)
ES (1) ES443790A1 (enrdf_load_stackoverflow)
FI (1) FI753312A7 (enrdf_load_stackoverflow)
FR (1) FR2295750A1 (enrdf_load_stackoverflow)
GB (1) GB1492140A (enrdf_load_stackoverflow)
HU (1) HU174324B (enrdf_load_stackoverflow)
IL (1) IL48416A (enrdf_load_stackoverflow)
LU (1) LU73971A1 (enrdf_load_stackoverflow)
NL (1) NL7514269A (enrdf_load_stackoverflow)
NO (1) NO141408C (enrdf_load_stackoverflow)
PH (1) PH12314A (enrdf_load_stackoverflow)
PL (1) PL101046B1 (enrdf_load_stackoverflow)
SE (1) SE417607B (enrdf_load_stackoverflow)
SU (1) SU612629A3 (enrdf_load_stackoverflow)
ZA (1) ZA756964B (enrdf_load_stackoverflow)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN120081720A (zh) * 2025-02-18 2025-06-03 天津汇仁恒通科技有限公司 一种二乙烯基芳香化合物的制备方法

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR71725B (enrdf_load_stackoverflow) * 1977-11-10 1983-06-22 Hoffmann La Roche
EP2467142B1 (en) 2009-08-17 2016-09-21 Memorial Sloan-Kettering Cancer Center 2-(Pyrimidin-5-yl)-thiopyrimidine derivatives as Hsp70 and Hsc70 modulators for the treatment of proliferative disorders
CN107074806B (zh) 2014-05-13 2021-04-23 纪念斯隆-凯特琳癌症中心 Hsp70调节子以及其制造和使用方法

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN120081720A (zh) * 2025-02-18 2025-06-03 天津汇仁恒通科技有限公司 一种二乙烯基芳香化合物的制备方法

Also Published As

Publication number Publication date
CH605828A5 (enrdf_load_stackoverflow) 1978-10-13
CU34406A (es) 1978-09-08
FR2295750A1 (fr) 1976-07-23
IL48416A0 (en) 1976-01-30
SU612629A3 (ru) 1978-06-25
ES443790A1 (es) 1977-12-16
NO141408C (no) 1980-03-05
ATA975975A (de) 1977-12-15
AU8643375A (en) 1977-05-12
SE417607B (sv) 1981-03-30
NO141408B (no) 1979-11-26
PH12314A (en) 1979-01-16
LU73971A1 (enrdf_load_stackoverflow) 1977-07-01
BR7508534A (pt) 1976-12-21
AU500102B2 (en) 1979-05-10
DK137797C (enrdf_load_stackoverflow) 1978-10-16
DK589675A (enrdf_load_stackoverflow) 1976-06-25
PL101046B1 (pl) 1978-11-30
HU174324B (hu) 1979-12-28
AT344704B (de) 1978-08-10
BE836996A (fr) 1976-06-23
JPS5191273A (enrdf_load_stackoverflow) 1976-08-10
DE2558150A1 (de) 1976-07-01
CH617191A5 (en) 1980-05-14
CA1059127A (en) 1979-07-24
DK137797B (da) 1978-05-08
FI753312A7 (enrdf_load_stackoverflow) 1976-06-25
FR2295750B1 (enrdf_load_stackoverflow) 1980-06-20
IL48416A (en) 1980-02-29
SE7514642L (sv) 1976-06-28
ZA756964B (en) 1976-10-27
NL7514269A (nl) 1976-06-28
DD123603A5 (enrdf_load_stackoverflow) 1977-01-05
NO754372L (enrdf_load_stackoverflow) 1976-06-25

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee