GB1485269A - Pharmaceutical compositions containing acetic acid derivatives - Google Patents

Pharmaceutical compositions containing acetic acid derivatives

Info

Publication number
GB1485269A
GB1485269A GB28416/74A GB2841674A GB1485269A GB 1485269 A GB1485269 A GB 1485269A GB 28416/74 A GB28416/74 A GB 28416/74A GB 2841674 A GB2841674 A GB 2841674A GB 1485269 A GB1485269 A GB 1485269A
Authority
GB
United Kingdom
Prior art keywords
acid
acetic acid
propyl
compositions containing
pharmaceutical compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB28416/74A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Labaz SA
Original Assignee
Labaz SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Labaz SA filed Critical Labaz SA
Priority to GB28416/74A priority Critical patent/GB1485269A/en
Priority to AR259339A priority patent/AR205748A1/en
Priority to IE1128/80A priority patent/IE42948B1/en
Priority to IE1323/75A priority patent/IE42947B1/en
Priority to GB2833376A priority patent/GB1486534A/en
Priority to FR7518489A priority patent/FR2276036A1/en
Priority to ZA00753800A priority patent/ZA753800B/en
Priority to NZ185111A priority patent/NZ185111A/en
Priority to NZ177837A priority patent/NZ177837A/en
Priority to HU75LA870A priority patent/HU174772B/en
Priority to NL7507253A priority patent/NL7507253A/en
Priority to CA229,907A priority patent/CA1041015A/en
Priority to DE19752528025 priority patent/DE2528025A1/en
Priority to AU82393/75A priority patent/AU493526B2/en
Priority to AT487575A priority patent/AT341490B/en
Priority to SE7507297A priority patent/SE427926B/en
Priority to IT24734/75A priority patent/IT1049449B/en
Priority to YU1629/75A priority patent/YU40439B/en
Priority to NO752270A priority patent/NO146905C/en
Priority to DK288775A priority patent/DK288775A/en
Priority to ES438905A priority patent/ES438905A1/en
Priority to OA55538A priority patent/OA05039A/en
Priority to JP50079960A priority patent/JPS6041058B2/en
Priority to FI751888A priority patent/FI66834C/en
Priority to CH325278A priority patent/CH609668A5/en
Priority to CH832675A priority patent/CH609667A5/en
Priority to MX720175U priority patent/MX5548E/en
Priority to AR261324A priority patent/AR212236A1/en
Priority to AT877576A priority patent/AT341491B/en
Publication of GB1485269A publication Critical patent/GB1485269A/en
Priority to SE7907843A priority patent/SE435275B/en
Priority to YU598/83A priority patent/YU41539B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/01—Saturated compounds having only one carboxyl group and containing hydroxy or O-metal groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/09—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by hydrolysis
    • C07C29/095—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by hydrolysis of esters of organic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/60—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by elimination of -OH groups, e.g. by dehydration
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/16—Preparation of carboxylic acids or their salts, halides or anhydrides by oxidation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/36—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by hydrogenation of carbon-to-carbon unsaturated bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/367—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by introduction of functional groups containing oxygen only in singly bound form
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/377—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by splitting-off hydrogen or functional groups; by hydrogenolysis of functional groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/41—Preparation of salts of carboxylic acids
    • C07C51/412—Preparation of salts of carboxylic acids by conversion of the acids, their salts, esters or anhydrides with the same carboxylic acid part
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C53/00—Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen
    • C07C53/126—Acids containing more than four carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/02—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
    • C07C57/03—Monocarboxylic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

1485269 Pharmaceutical compositions containing acetic acid derivatives LABAZ 12 June 1975 [26 June 1974] 28416/74 Heading ASB [Also in Division C2] Pharmaceutical or veterinary compositions, usable in treating non-human subjects with central neurological disorders, comprise as an active ingredient an acetic acid derivative of formula: where R represents where R, and R 2 may be the same or different and each represent an alkyl group with 1-4 carbon atoms, n is an integer from 1-3 inclusive and R 3 and R 4 , which are identical, each represent a straight chain alkyl radical with 1-4 carbon atoms, in association with a carrier or excipient other than Ordinary tap water or a common organic solvent. Preferred active ingredients are 3-n-propyl hexanoic acid; 4-n-propyl-heptanoic acid, 3-n-butyl heptanoic acid, 3-Methyl-butanoic acid, 3-ethyl-pentanoic acid and 5-n-propyl octanoic acid. The composition is preferably in a unit dosage form for rectal or oral administration.
GB28416/74A 1974-06-26 1974-06-26 Pharmaceutical compositions containing acetic acid derivatives Expired GB1485269A (en)

Priority Applications (31)

Application Number Priority Date Filing Date Title
GB28416/74A GB1485269A (en) 1974-06-26 1974-06-26 Pharmaceutical compositions containing acetic acid derivatives
AR259339A AR205748A1 (en) 1974-06-26 1975-01-01 PROCEDURE FOR THE PREPARATION OF SUBSTITUTED 3- OR 4-ALKYL FORMIC ACIDS AND THEIR SALTS
IE1128/80A IE42948B1 (en) 1974-06-26 1975-06-12 Pharmaceutically acceptable salts of alkanoic acid derivatives and compositions containing the same
IE1323/75A IE42947B1 (en) 1974-06-26 1975-06-12 Pharmaceutical compositions containing acetic acid derivatives
GB2833376A GB1486534A (en) 1974-06-26 1975-06-12 Pharmaceutically acceptable salts of alkanoic acid derivatives and compositions containing the same
FR7518489A FR2276036A1 (en) 1974-06-26 1975-06-13 ACETIC ACID ACTIVE DERIVATIVES, THERAPEUTIC COMPOSITIONS CONTAINING THEM AND THE PROCESSES FOR THE PREPARATION OF THESE DERIVATIVES AND COMPOSITIONS
ZA00753800A ZA753800B (en) 1974-06-26 1975-06-13 Acetic acid derivatives having pharmocological activity and compositions containing the same
NZ185111A NZ185111A (en) 1974-06-26 1975-06-16 Salts of alkynoic acids and pharmaceutical compositions
NZ177837A NZ177837A (en) 1974-06-26 1975-06-16 Pharmaceutical and veterinary compositions containing acetic acid derivatives
HU75LA870A HU174772B (en) 1974-06-26 1975-06-18 Process for producing pharmaceutically active acetic acid derivatives
NL7507253A NL7507253A (en) 1974-06-26 1975-06-18 ACETIC ACID DERIVATIVES AND PROCEDURES FOR THEIR PREPARATION AND USE.
CA229,907A CA1041015A (en) 1974-06-26 1975-06-23 Acetic acid derivatives pharmacological activity and compositions containing the same
DE19752528025 DE2528025A1 (en) 1974-06-26 1975-06-24 MEDICINAL PRODUCTS AND METHOD FOR PRODUCING IT
AU82393/75A AU493526B2 (en) 1974-06-26 1975-06-24 Acetic acid derivatives having parmacological activity and composition containing thesame
SE7507297A SE427926B (en) 1974-06-26 1975-06-25 ANALOGY PROCEDURE FOR THE PREPARATION OF ETHIC ACID DERIVATIVES
AT487575A AT341490B (en) 1974-06-26 1975-06-25 METHOD FOR PRODUCING NEW ALKALINE SALTS OF DAILKYL PROPIONIC ACIDS
IT24734/75A IT1049449B (en) 1974-06-26 1975-06-25 ACETIC ACID DERIVATIVES HAVING PHARMACOLOGICAL ACTIVITIES AND COMPOSITIONS CONTAINING THEM
YU1629/75A YU40439B (en) 1974-06-26 1975-06-25 Process for obtaining acetic acid derivatives
NO752270A NO146905C (en) 1974-06-26 1975-06-25 ANALOGY PROCEDURE FOR THE PREPARATION OF PHYSIOLOGICALLY ACTIVE OMEGA-DIALKYL-ALKANIC ACID DERIVATIVES
DK288775A DK288775A (en) 1974-06-26 1975-06-25 ALKALIMETAL SALTS OF ACTIC ACID DERIVATIVES AND PROCEDURES FOR THE PREPARATION
FI751888A FI66834C (en) 1974-06-26 1975-06-26 FOERFARANDE FOER FRAMSTAELLNING AV TERAPEUTISKT AKTIVA OMEGA DIALKYLALKANSYREDERIVAT
OA55538A OA05039A (en) 1974-06-26 1975-06-26 Process for the preparation of active derivatives of acetic acid.
JP50079960A JPS6041058B2 (en) 1974-06-26 1975-06-26 Method for producing acetic acid derivatives
ES438905A ES438905A1 (en) 1974-06-26 1975-06-26 Pharmaceutical compositions containing acetic acid derivatives
CH325278A CH609668A5 (en) 1974-06-26 1975-06-26 Process for the preparation of acetic acid derivatives
CH832675A CH609667A5 (en) 1974-06-26 1975-06-26 Process for the preparation of acetic acid derivatives
MX720175U MX5548E (en) 1974-06-26 1975-06-26 PROCEDURE FOR PREPARING ACETIC ACID DERIVATIVES
AR261324A AR212236A1 (en) 1974-06-26 1975-11-24 PROCEDURE FOR PREPARING BETA-DIALKYL-SUBSTITUTED PROPIONIC ACID ALKALINE METAL SALTS
AT877576A AT341491B (en) 1974-06-26 1976-11-26 PROCESS FOR THE PREPARATION OF NEW SALT OF OMEGA-DIPROPYLALCANIC ACIDS
SE7907843A SE435275B (en) 1974-06-26 1979-09-21 ANALOGY PROCEDURE FOR PREPARING NEW ETHIC ACID DERIVATIVES
YU598/83A YU41539B (en) 1974-06-26 1983-03-11 Process for btaining new acetic acid derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB28416/74A GB1485269A (en) 1974-06-26 1974-06-26 Pharmaceutical compositions containing acetic acid derivatives

Publications (1)

Publication Number Publication Date
GB1485269A true GB1485269A (en) 1977-09-08

Family

ID=10275286

Family Applications (1)

Application Number Title Priority Date Filing Date
GB28416/74A Expired GB1485269A (en) 1974-06-26 1974-06-26 Pharmaceutical compositions containing acetic acid derivatives

Country Status (21)

Country Link
JP (1) JPS6041058B2 (en)
AR (2) AR205748A1 (en)
AT (1) AT341490B (en)
CA (1) CA1041015A (en)
CH (2) CH609668A5 (en)
DE (1) DE2528025A1 (en)
DK (1) DK288775A (en)
ES (1) ES438905A1 (en)
FI (1) FI66834C (en)
FR (1) FR2276036A1 (en)
GB (1) GB1485269A (en)
HU (1) HU174772B (en)
IE (1) IE42947B1 (en)
IT (1) IT1049449B (en)
NL (1) NL7507253A (en)
NO (1) NO146905C (en)
NZ (1) NZ177837A (en)
OA (1) OA05039A (en)
SE (2) SE427926B (en)
YU (2) YU40439B (en)
ZA (1) ZA753800B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2558154B1 (en) * 1984-01-16 1986-08-29 Pf Medicament C10 TO C20 BRANCHED FATTY ACIDS USEFUL AS MEDICAMENTS, AND PROCESS FOR THEIR PREPARATION
GB2323706B (en) * 1997-03-13 2002-02-13 United Microelectronics Corp Method to inhibit the formation of ion implantation induced edge defects

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2484486A (en) * 1946-05-15 1949-10-11 Eastman Kodak Co Preparation of carboxylic acids by the reduction of beta lactones
US2484500A (en) * 1947-10-28 1949-10-11 Eastman Kodak Co Preparation of propionic acids by reduction of beta propiono lactones
FR2442M (en) * 1962-10-17 1964-04-06 Henry Eugene Dipropylacetic acid and its derivatives as new central nervous system depressants.

Also Published As

Publication number Publication date
AT341490B (en) 1978-02-10
NO752270L (en) 1975-12-30
NO146905B (en) 1982-09-20
SE427926B (en) 1983-05-24
FR2276036A1 (en) 1976-01-23
SE7907843L (en) 1979-09-21
FI66834C (en) 1984-12-10
HU174772B (en) 1980-03-28
AU8239375A (en) 1977-01-06
CH609667A5 (en) 1979-03-15
CH609668A5 (en) 1979-03-15
ES438905A1 (en) 1977-02-01
ZA753800B (en) 1976-05-26
IE42947L (en) 1975-12-26
FR2276036B1 (en) 1978-11-10
AR205748A1 (en) 1976-05-31
IT1049449B (en) 1981-01-20
NL7507253A (en) 1975-12-30
FI751888A (en) 1975-12-27
NO146905C (en) 1982-12-29
CA1041015A (en) 1978-10-24
YU40439B (en) 1986-02-28
FI66834B (en) 1984-08-31
JPS5129216A (en) 1976-03-12
YU41539B (en) 1987-08-31
IE42947B1 (en) 1980-11-19
DK288775A (en) 1975-12-27
YU162975A (en) 1983-09-30
DE2528025A1 (en) 1976-01-15
SE435275B (en) 1984-09-17
YU59883A (en) 1983-12-31
JPS6041058B2 (en) 1985-09-13
AR212236A1 (en) 1978-06-15
OA05039A (en) 1980-12-31
SE7507297L (en) 1975-12-29
ATA487575A (en) 1977-06-15
NZ177837A (en) 1978-12-18

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
732 Registration of transactions, instruments or events in the register (sect. 32/1977)
PCNP Patent ceased through non-payment of renewal fee