IT1049449B - ACETIC ACID DERIVATIVES HAVING PHARMACOLOGICAL ACTIVITIES AND COMPOSITIONS CONTAINING THEM - Google Patents

ACETIC ACID DERIVATIVES HAVING PHARMACOLOGICAL ACTIVITIES AND COMPOSITIONS CONTAINING THEM

Info

Publication number
IT1049449B
IT1049449B IT24734/75A IT2473475A IT1049449B IT 1049449 B IT1049449 B IT 1049449B IT 24734/75 A IT24734/75 A IT 24734/75A IT 2473475 A IT2473475 A IT 2473475A IT 1049449 B IT1049449 B IT 1049449B
Authority
IT
Italy
Prior art keywords
acid
acetic acid
propyl
compositions containing
june
Prior art date
Application number
IT24734/75A
Other languages
Italian (it)
Inventor
A Boucherle
M Broll
P Eymard
G Taillandier
B Ferrandes
G Benoit
Original Assignee
Labaz
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Labaz filed Critical Labaz
Application granted granted Critical
Publication of IT1049449B publication Critical patent/IT1049449B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/01—Saturated compounds having only one carboxyl group and containing hydroxy or O-metal groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/09—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by hydrolysis
    • C07C29/095—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by hydrolysis of esters of organic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/60—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by elimination of -OH groups, e.g. by dehydration
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/16—Preparation of carboxylic acids or their salts, halides or anhydrides by oxidation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/36—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by hydrogenation of carbon-to-carbon unsaturated bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/367—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by introduction of functional groups containing oxygen only in singly bound form
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/377—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by splitting-off hydrogen or functional groups; by hydrogenolysis of functional groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/41—Preparation of salts of carboxylic acids
    • C07C51/412—Preparation of salts of carboxylic acids by conversion of the acids, their salts, esters or anhydrides with the same carboxylic acid part
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C53/00—Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen
    • C07C53/126—Acids containing more than four carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/02—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
    • C07C57/03—Monocarboxylic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

1485269 Pharmaceutical compositions containing acetic acid derivatives LABAZ 12 June 1975 [26 June 1974] 28416/74 Heading ASB [Also in Division C2] Pharmaceutical or veterinary compositions, usable in treating non-human subjects with central neurological disorders, comprise as an active ingredient an acetic acid derivative of formula: where R represents where R, and R 2 may be the same or different and each represent an alkyl group with 1-4 carbon atoms, n is an integer from 1-3 inclusive and R 3 and R 4 , which are identical, each represent a straight chain alkyl radical with 1-4 carbon atoms, in association with a carrier or excipient other than Ordinary tap water or a common organic solvent. Preferred active ingredients are 3-n-propyl hexanoic acid; 4-n-propyl-heptanoic acid, 3-n-butyl heptanoic acid, 3-Methyl-butanoic acid, 3-ethyl-pentanoic acid and 5-n-propyl octanoic acid. The composition is preferably in a unit dosage form for rectal or oral administration.
IT24734/75A 1974-06-26 1975-06-25 ACETIC ACID DERIVATIVES HAVING PHARMACOLOGICAL ACTIVITIES AND COMPOSITIONS CONTAINING THEM IT1049449B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB28416/74A GB1485269A (en) 1974-06-26 1974-06-26 Pharmaceutical compositions containing acetic acid derivatives

Publications (1)

Publication Number Publication Date
IT1049449B true IT1049449B (en) 1981-01-20

Family

ID=10275286

Family Applications (1)

Application Number Title Priority Date Filing Date
IT24734/75A IT1049449B (en) 1974-06-26 1975-06-25 ACETIC ACID DERIVATIVES HAVING PHARMACOLOGICAL ACTIVITIES AND COMPOSITIONS CONTAINING THEM

Country Status (21)

Country Link
JP (1) JPS6041058B2 (en)
AR (2) AR205748A1 (en)
AT (1) AT341490B (en)
CA (1) CA1041015A (en)
CH (2) CH609667A5 (en)
DE (1) DE2528025A1 (en)
DK (1) DK288775A (en)
ES (1) ES438905A1 (en)
FI (1) FI66834C (en)
FR (1) FR2276036A1 (en)
GB (1) GB1485269A (en)
HU (1) HU174772B (en)
IE (1) IE42947B1 (en)
IT (1) IT1049449B (en)
NL (1) NL7507253A (en)
NO (1) NO146905C (en)
NZ (1) NZ177837A (en)
OA (1) OA05039A (en)
SE (2) SE427926B (en)
YU (2) YU40439B (en)
ZA (1) ZA753800B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2558154B1 (en) * 1984-01-16 1986-08-29 Pf Medicament C10 TO C20 BRANCHED FATTY ACIDS USEFUL AS MEDICAMENTS, AND PROCESS FOR THEIR PREPARATION
GB2323706B (en) * 1997-03-13 2002-02-13 United Microelectronics Corp Method to inhibit the formation of ion implantation induced edge defects

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2484486A (en) * 1946-05-15 1949-10-11 Eastman Kodak Co Preparation of carboxylic acids by the reduction of beta lactones
US2484500A (en) * 1947-10-28 1949-10-11 Eastman Kodak Co Preparation of propionic acids by reduction of beta propiono lactones
FR2442M (en) * 1962-10-17 1964-04-06 Henry Eugene Dipropylacetic acid and its derivatives as new central nervous system depressants.

Also Published As

Publication number Publication date
IE42947B1 (en) 1980-11-19
NO752270L (en) 1975-12-30
OA05039A (en) 1980-12-31
FI66834B (en) 1984-08-31
AT341490B (en) 1978-02-10
SE7507297L (en) 1975-12-29
GB1485269A (en) 1977-09-08
AR205748A1 (en) 1976-05-31
NZ177837A (en) 1978-12-18
ATA487575A (en) 1977-06-15
SE7907843L (en) 1979-09-21
NO146905C (en) 1982-12-29
CH609667A5 (en) 1979-03-15
NO146905B (en) 1982-09-20
FI66834C (en) 1984-12-10
DK288775A (en) 1975-12-27
SE435275B (en) 1984-09-17
FR2276036A1 (en) 1976-01-23
JPS5129216A (en) 1976-03-12
JPS6041058B2 (en) 1985-09-13
YU162975A (en) 1983-09-30
AU8239375A (en) 1977-01-06
CH609668A5 (en) 1979-03-15
ZA753800B (en) 1976-05-26
YU59883A (en) 1983-12-31
NL7507253A (en) 1975-12-30
FI751888A (en) 1975-12-27
SE427926B (en) 1983-05-24
FR2276036B1 (en) 1978-11-10
CA1041015A (en) 1978-10-24
AR212236A1 (en) 1978-06-15
DE2528025A1 (en) 1976-01-15
HU174772B (en) 1980-03-28
ES438905A1 (en) 1977-02-01
YU40439B (en) 1986-02-28
IE42947L (en) 1975-12-26
YU41539B (en) 1987-08-31

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