GB1484848A - Phenyl-alkane-carboxylic acid derivatives - Google Patents

Phenyl-alkane-carboxylic acid derivatives

Info

Publication number
GB1484848A
GB1484848A GB15550/76A GB1555076A GB1484848A GB 1484848 A GB1484848 A GB 1484848A GB 15550/76 A GB15550/76 A GB 15550/76A GB 1555076 A GB1555076 A GB 1555076A GB 1484848 A GB1484848 A GB 1484848A
Authority
GB
United Kingdom
Prior art keywords
substituted
unsubstituted
alkane
carboxylic acid
alkoxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB15550/76A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19752517229 external-priority patent/DE2517229A1/de
Priority claimed from DE19762604560 external-priority patent/DE2604560A1/de
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Publication of GB1484848A publication Critical patent/GB1484848A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81Amides; Imides
    • C07D213/82Amides; Imides in position 3
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/24Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/66Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00Systems containing at least three condensed rings
    • C07C2603/02Ortho- or ortho- and peri-condensed systems
    • C07C2603/04Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/06Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
    • C07C2603/10Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
    • C07C2603/12Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
    • C07C2603/18Fluorenes; Hydrogenated fluorenes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Quinoline Compounds (AREA)
  • Furan Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Indole Compounds (AREA)
GB15550/76A 1975-04-18 1976-04-15 Phenyl-alkane-carboxylic acid derivatives Expired GB1484848A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19752517229 DE2517229A1 (de) 1975-04-18 1975-04-18 Phenylalkylcarbonsaeure-derivate und verfahren zu ihrer herstellung
DE19762604560 DE2604560A1 (de) 1976-02-06 1976-02-06 Phenylalkancarbonsaeure-derivate und verfahren zu ihrer herstellung

Publications (1)

Publication Number Publication Date
GB1484848A true GB1484848A (en) 1977-09-08

Family

ID=25768786

Family Applications (1)

Application Number Title Priority Date Filing Date
GB15550/76A Expired GB1484848A (en) 1975-04-18 1976-04-15 Phenyl-alkane-carboxylic acid derivatives

Country Status (23)

Country Link
US (1) US4113871A (US20020095090A1-20020718-M00002.png)
JP (1) JPS51136646A (US20020095090A1-20020718-M00002.png)
AR (1) AR213174A1 (US20020095090A1-20020718-M00002.png)
AT (1) AT345795B (US20020095090A1-20020718-M00002.png)
AU (1) AU497513B2 (US20020095090A1-20020718-M00002.png)
BG (1) BG26518A3 (US20020095090A1-20020718-M00002.png)
CA (1) CA1047513A (US20020095090A1-20020718-M00002.png)
DD (1) DD124974A5 (US20020095090A1-20020718-M00002.png)
DK (1) DK148576A (US20020095090A1-20020718-M00002.png)
ES (1) ES446976A1 (US20020095090A1-20020718-M00002.png)
FI (1) FI761004A (US20020095090A1-20020718-M00002.png)
FR (1) FR2307528A1 (US20020095090A1-20020718-M00002.png)
GB (1) GB1484848A (US20020095090A1-20020718-M00002.png)
HU (1) HU177559B (US20020095090A1-20020718-M00002.png)
IE (1) IE42712B1 (US20020095090A1-20020718-M00002.png)
IL (1) IL49411A (US20020095090A1-20020718-M00002.png)
LU (1) LU74786A1 (US20020095090A1-20020718-M00002.png)
NL (1) NL7603947A (US20020095090A1-20020718-M00002.png)
PL (1) PL101299B1 (US20020095090A1-20020718-M00002.png)
PT (1) PT65019B (US20020095090A1-20020718-M00002.png)
RO (1) RO73520A (US20020095090A1-20020718-M00002.png)
SE (1) SE423231B (US20020095090A1-20020718-M00002.png)
SU (1) SU618038A3 (US20020095090A1-20020718-M00002.png)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0172147A2 (en) * 1984-08-14 1986-02-19 Medosan Industrie Biochimiche Riunite S.r.l. Amide derivatives of 2-(p-aminobenzyl)-butyric acid and esters thereof having hypolipidemizing activity
US5741926A (en) * 1997-02-12 1998-04-21 Shaman Pharmaceuticals, Inc. Aniline derivatives having antihyperglycemic activity
US8686154B2 (en) 1997-02-07 2014-04-01 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2532420A1 (de) * 1975-07-19 1977-02-03 Boehringer Mannheim Gmbh Phenylessigsaeure-derivate und verfahren zu ihrer herstellung
LU79008A1 (de) * 1978-02-03 1979-09-06 Byk Gulden Lomberg Chem Fab W-(n-alkyl-n-benzoyl-amino)-phenylalkansaeuren,ihre verwendung und herstellung sowie sie enthaltende arzneimittel
IT1121577B (it) * 1979-06-14 1986-04-02 Wassermann Spa A Procedimento per la produzione di carbossammido-etilbenzen-4-4solfonammidi
DE3062216D1 (en) * 1979-09-06 1983-04-07 Beecham Group Plc Cinnamic acid derivatives, their preparation, and pharmaceutical compositions containing them
DE3000377A1 (de) * 1980-01-07 1981-07-09 Boehringer Mannheim Gmbh, 6800 Mannheim Neue sulfonamide, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel
US4413011A (en) * 1981-02-26 1983-11-01 Warner-Lambert Company Substituted 2,2-dimethyl-5-phenoxypentanoic acid benzamides as anti-arteriosclerotic agents and method
PT77219B (fr) * 1982-08-24 1986-02-04 May & Baker Ltd Procede de preparation des derives de la benzamide
US4689182A (en) * 1985-12-20 1987-08-25 Warner-Lambert Company Benzoic acid and benzoic acid ester derivatives having anti-inflammatory and analgesic activity
CA2057324A1 (en) * 1990-12-18 1992-06-19 Lora Louise Fitch Benzamide and sulfonamide hypoglycemic agents
BR9813019A (pt) * 1997-10-02 2000-09-05 Sankyo Co Derivados do ácido amidocarboxìlico, agentes para diminuir a glicose do sangue, redutor de lipìdio, para melhorar a resistência à insulina, anti-inflamatório, para imuno regulagem, para inibir a aldose reductase, para inibir a 5-lipoxigenase, para a geração de supressor de peróxido de lipìdio, para ativar a ppar, para minorar a osteoporose, e, composições para a terapia ou prevenção da diabete melito, da hiperlipemia, da obesidade, da tolerância à glicose prejudicada, da resistência à insulina que não a igt, do fìgado gorduroso, de complicações diabéticas, da arterioesclerose, da diabete melito gestacional, da sìndrome do ovário policìstico, da artroesteìte, da artrite reumática, de doenças alérgicas, da asma, do câncer, de doenças auto imunes, da pancreatite, e de cataratas
JP4618845B2 (ja) * 1999-06-09 2011-01-26 杏林製薬株式会社 ヒトペルオキシゾーム増殖薬活性化受容体(PPAR)αアゴニストとしての置換フェニルプロピオン酸誘導体
AU2001258784A1 (en) * 2000-05-22 2001-12-03 Takeda Chemical Industries Ltd. Tyrosine phosphatase inhibitors
MY129000A (en) * 2000-08-31 2007-03-30 Tanabe Seiyaku Co INHIBITORS OF a4 MEDIATED CELL ADHESION
CA2430846A1 (en) * 2000-12-05 2002-06-13 Kyorin Pharmaceutical Co., Ltd. Substituted carboxylic acid derivatives
NZ531153A (en) * 2001-08-09 2005-10-28 Ono Pharmaceutical Co Carboxylic acid derivative compounds and drugs comprising these compounds as the active ingredient
DK1517883T3 (da) * 2002-06-20 2008-05-26 Astrazeneca Ab Ortho-substituerede benzoesyrederivater til behandling af insulinresistens
SE0201937D0 (sv) * 2002-06-20 2002-06-20 Astrazeneca Ab Therapeutic agents
JPWO2006016637A1 (ja) * 2004-08-11 2008-05-01 杏林製薬株式会社 新規環状アミノ安息香酸誘導体
US8101774B2 (en) * 2004-10-18 2012-01-24 Japan Tobacco Inc. Ester derivatives and medicinal use thereof

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0172147A2 (en) * 1984-08-14 1986-02-19 Medosan Industrie Biochimiche Riunite S.r.l. Amide derivatives of 2-(p-aminobenzyl)-butyric acid and esters thereof having hypolipidemizing activity
EP0172147A3 (en) * 1984-08-14 1988-07-13 Medosan Industrie Biochimiche Riunite S.P.A. Amide derivatives of 2-(p-aminobenzyl)-butyric acid and esters thereof having hypolipidemizing activity
US8686154B2 (en) 1997-02-07 2014-04-01 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5741926A (en) * 1997-02-12 1998-04-21 Shaman Pharmaceuticals, Inc. Aniline derivatives having antihyperglycemic activity

Also Published As

Publication number Publication date
FR2307528A1 (fr) 1976-11-12
AR213174A1 (es) 1978-12-29
US4113871A (en) 1978-09-12
IE42712L (en) 1976-10-18
SE423231B (sv) 1982-04-26
HU177559B (en) 1981-11-28
IE42712B1 (en) 1980-10-08
PT65019A (de) 1976-05-01
IL49411A0 (en) 1976-06-30
JPS51136646A (en) 1976-11-26
ATA283676A (de) 1978-02-15
FR2307528B1 (US20020095090A1-20020718-M00002.png) 1981-11-13
AU1315776A (en) 1977-10-27
RO73520A (ro) 1980-12-30
AT345795B (de) 1978-10-10
ES446976A1 (es) 1977-06-01
AU497513B2 (en) 1978-12-14
NL7603947A (nl) 1976-10-20
BG26518A3 (US20020095090A1-20020718-M00002.png) 1979-04-12
CA1047513A (en) 1979-01-30
PL101299B1 (pl) 1978-12-30
LU74786A1 (US20020095090A1-20020718-M00002.png) 1977-01-12
DK148576A (da) 1976-10-19
PT65019B (de) 1977-09-09
IL49411A (en) 1979-12-30
FI761004A (US20020095090A1-20020718-M00002.png) 1976-10-19
SE7604381L (sv) 1976-10-19
DD124974A5 (US20020095090A1-20020718-M00002.png) 1977-03-23
SU618038A3 (ru) 1978-07-30

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee