GB1472966A - Cephalosporin purification process - Google Patents
Cephalosporin purification processInfo
- Publication number
- GB1472966A GB1472966A GB238275A GB238275A GB1472966A GB 1472966 A GB1472966 A GB 1472966A GB 238275 A GB238275 A GB 238275A GB 238275 A GB238275 A GB 238275A GB 1472966 A GB1472966 A GB 1472966A
- Authority
- GB
- United Kingdom
- Prior art keywords
- carboxylic acid
- salt
- adsorbent
- aqueous solution
- cephalosporin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/36—Methylene radicals, substituted by sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/02—Preparation
- C07D501/12—Separation; Purification
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US43591174A | 1974-01-23 | 1974-01-23 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1472966A true GB1472966A (en) | 1977-05-11 |
Family
ID=23730331
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB238275A Expired GB1472966A (en) | 1974-01-23 | 1975-01-20 | Cephalosporin purification process |
Country Status (9)
Country | Link |
---|---|
JP (1) | JPS50106996A (xx) |
BE (1) | BE824028A (xx) |
CH (1) | CH613971A5 (xx) |
DE (1) | DE2502097A1 (xx) |
ES (1) | ES433995A1 (xx) |
FR (1) | FR2258388B1 (xx) |
GB (1) | GB1472966A (xx) |
IE (1) | IE40481B1 (xx) |
NL (1) | NL7500805A (xx) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AT386206B (de) * | 1984-03-09 | 1988-07-25 | Glaxo Group Ltd | Verfahren zur wiedergewinnung von (6r, 7r)7-( (z)-2-(2-aminothiazol-4-yl)-2-2(2-carboxyprop-2 oxyimino)-acetamido)-3-(1-pyridiniummethyl)ceph-3-em-4-carboxylat (ceftazidim) aus einer dieses enthaltenden waessrigen loesung |
EP0697396A1 (en) * | 1994-08-17 | 1996-02-21 | General Electric Company | Adsorption process for amine or amine salt recovery from aqueous brine solutions |
ES2129006A1 (es) * | 1996-10-02 | 1999-05-16 | Otsuka Kagaku Kk | Procedimiento para producir cefazolina. |
CN104610282A (zh) * | 2015-02-14 | 2015-05-13 | 石药集团中诺药业(石家庄)有限公司 | 一种头孢唑啉酸的提纯方法 |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5398989A (en) * | 1977-02-09 | 1978-08-29 | Fujisawa Pharmaceut Co Ltd | Purification of cephalosporin compounds |
US4115644A (en) * | 1977-09-19 | 1978-09-19 | Eli Lilly And Company | Process for preparing pure cefamandole from alkali metal and ammonium salts thereof |
JPS5665894A (en) * | 1979-10-31 | 1981-06-03 | Asahi Chem Ind Co Ltd | Purification of 7-aminocephalosporanic acid derivative |
JPS60161990A (ja) * | 1984-02-02 | 1985-08-23 | Shionogi & Co Ltd | オキサセフアロスポリンの精製法 |
WO1998055484A1 (en) * | 1997-06-04 | 1998-12-10 | Biochemie Gesellschaft Mbh | Improved precipitation process of 7-aminocephalosporanic acid (7-aca) |
-
1974
- 1974-12-31 BE BE152080A patent/BE824028A/xx not_active IP Right Cessation
-
1975
- 1975-01-20 DE DE19752502097 patent/DE2502097A1/de not_active Withdrawn
- 1975-01-20 IE IE10375A patent/IE40481B1/xx unknown
- 1975-01-20 FR FR7501678A patent/FR2258388B1/fr not_active Expired
- 1975-01-20 GB GB238275A patent/GB1472966A/en not_active Expired
- 1975-01-21 ES ES433995A patent/ES433995A1/es not_active Expired
- 1975-01-22 JP JP50010125A patent/JPS50106996A/ja active Pending
- 1975-01-22 CH CH83375A patent/CH613971A5/xx not_active IP Right Cessation
- 1975-01-23 NL NL7500805A patent/NL7500805A/xx not_active Application Discontinuation
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AT386206B (de) * | 1984-03-09 | 1988-07-25 | Glaxo Group Ltd | Verfahren zur wiedergewinnung von (6r, 7r)7-( (z)-2-(2-aminothiazol-4-yl)-2-2(2-carboxyprop-2 oxyimino)-acetamido)-3-(1-pyridiniummethyl)ceph-3-em-4-carboxylat (ceftazidim) aus einer dieses enthaltenden waessrigen loesung |
US4769450A (en) * | 1984-03-09 | 1988-09-06 | Glaxo Group Limited | Process for recovering ceftazidime |
EP0697396A1 (en) * | 1994-08-17 | 1996-02-21 | General Electric Company | Adsorption process for amine or amine salt recovery from aqueous brine solutions |
ES2129006A1 (es) * | 1996-10-02 | 1999-05-16 | Otsuka Kagaku Kk | Procedimiento para producir cefazolina. |
CN104610282A (zh) * | 2015-02-14 | 2015-05-13 | 石药集团中诺药业(石家庄)有限公司 | 一种头孢唑啉酸的提纯方法 |
Also Published As
Publication number | Publication date |
---|---|
CH613971A5 (en) | 1979-10-31 |
FR2258388A1 (xx) | 1975-08-18 |
IE40481B1 (en) | 1979-06-06 |
FR2258388B1 (xx) | 1978-07-07 |
IE40481L (en) | 1975-07-23 |
BE824028A (fr) | 1975-06-30 |
ES433995A1 (es) | 1976-11-16 |
NL7500805A (nl) | 1975-07-25 |
DE2502097A1 (de) | 1975-07-24 |
JPS50106996A (xx) | 1975-08-22 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed | ||
PCNP | Patent ceased through non-payment of renewal fee |