BE824028A - Procede pour la purification de cephalosporines comportant un groupe acide carboxylique libre - Google Patents

Procede pour la purification de cephalosporines comportant un groupe acide carboxylique libre

Info

Publication number
BE824028A
BE824028A BE152080A BE152080A BE824028A BE 824028 A BE824028 A BE 824028A BE 152080 A BE152080 A BE 152080A BE 152080 A BE152080 A BE 152080A BE 824028 A BE824028 A BE 824028A
Authority
BE
Belgium
Prior art keywords
purification
carboxylic acid
acid group
free carboxylic
cephalosporins containing
Prior art date
Application number
BE152080A
Other languages
English (en)
French (fr)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of BE824028A publication Critical patent/BE824028A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/247-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36Methylene radicals, substituted by sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02Preparation
    • C07D501/12Separation; Purification

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
BE152080A 1974-01-23 1974-12-31 Procede pour la purification de cephalosporines comportant un groupe acide carboxylique libre BE824028A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US43591174A 1974-01-23 1974-01-23

Publications (1)

Publication Number Publication Date
BE824028A true BE824028A (fr) 1975-06-30

Family

ID=23730331

Family Applications (1)

Application Number Title Priority Date Filing Date
BE152080A BE824028A (fr) 1974-01-23 1974-12-31 Procede pour la purification de cephalosporines comportant un groupe acide carboxylique libre

Country Status (9)

Country Link
JP (1) JPS50106996A (xx)
BE (1) BE824028A (xx)
CH (1) CH613971A5 (xx)
DE (1) DE2502097A1 (xx)
ES (1) ES433995A1 (xx)
FR (1) FR2258388B1 (xx)
GB (1) GB1472966A (xx)
IE (1) IE40481B1 (xx)
NL (1) NL7500805A (xx)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5398989A (en) * 1977-02-09 1978-08-29 Fujisawa Pharmaceut Co Ltd Purification of cephalosporin compounds
US4115644A (en) * 1977-09-19 1978-09-19 Eli Lilly And Company Process for preparing pure cefamandole from alkali metal and ammonium salts thereof
JPS5665894A (en) * 1979-10-31 1981-06-03 Asahi Chem Ind Co Ltd Purification of 7-aminocephalosporanic acid derivative
JPS60161990A (ja) * 1984-02-02 1985-08-23 Shionogi & Co Ltd オキサセフアロスポリンの精製法
GB8406218D0 (en) * 1984-03-09 1984-04-11 Glaxo Group Ltd Process
EP0697396B1 (en) * 1994-08-17 1999-04-14 General Electric Company Adsorption process for amine or amine salt recovery from aqueous brine solutions
JPH10101679A (ja) * 1996-10-02 1998-04-21 Otsuka Chem Co Ltd セファゾリンの製造法
CA2292618C (en) * 1997-06-04 2007-07-31 Biochemie Gesellschaft M.B.H. Improved precipitation process of 7-aminocephalosporanic acid (7-aca)
CN104610282B (zh) * 2015-02-14 2017-03-15 石药集团中诺药业(石家庄)有限公司 一种头孢唑啉酸的提纯方法

Also Published As

Publication number Publication date
NL7500805A (nl) 1975-07-25
IE40481L (en) 1975-07-23
CH613971A5 (en) 1979-10-31
FR2258388A1 (xx) 1975-08-18
GB1472966A (en) 1977-05-11
DE2502097A1 (de) 1975-07-24
FR2258388B1 (xx) 1978-07-07
JPS50106996A (xx) 1975-08-22
ES433995A1 (es) 1976-11-16
IE40481B1 (en) 1979-06-06

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: SMITHKLINE CORP.

Effective date: 19881231