BE824028A - Procede pour la purification de cephalosporines comportant un groupe acide carboxylique libre - Google Patents
Procede pour la purification de cephalosporines comportant un groupe acide carboxylique libreInfo
- Publication number
- BE824028A BE824028A BE152080A BE152080A BE824028A BE 824028 A BE824028 A BE 824028A BE 152080 A BE152080 A BE 152080A BE 152080 A BE152080 A BE 152080A BE 824028 A BE824028 A BE 824028A
- Authority
- BE
- Belgium
- Prior art keywords
- purification
- carboxylic acid
- acid group
- free carboxylic
- cephalosporins containing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/36—Methylene radicals, substituted by sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/02—Preparation
- C07D501/12—Separation; Purification
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
- Peptides Or Proteins (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US43591174A | 1974-01-23 | 1974-01-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BE824028A true BE824028A (fr) | 1975-06-30 |
Family
ID=23730331
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BE152080A BE824028A (fr) | 1974-01-23 | 1974-12-31 | Procede pour la purification de cephalosporines comportant un groupe acide carboxylique libre |
Country Status (9)
| Country | Link |
|---|---|
| JP (1) | JPS50106996A (xx) |
| BE (1) | BE824028A (xx) |
| CH (1) | CH613971A5 (xx) |
| DE (1) | DE2502097A1 (xx) |
| ES (1) | ES433995A1 (xx) |
| FR (1) | FR2258388B1 (xx) |
| GB (1) | GB1472966A (xx) |
| IE (1) | IE40481B1 (xx) |
| NL (1) | NL7500805A (xx) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5398989A (en) * | 1977-02-09 | 1978-08-29 | Fujisawa Pharmaceut Co Ltd | Purification of cephalosporin compounds |
| US4115644A (en) * | 1977-09-19 | 1978-09-19 | Eli Lilly And Company | Process for preparing pure cefamandole from alkali metal and ammonium salts thereof |
| JPS5665894A (en) * | 1979-10-31 | 1981-06-03 | Asahi Chem Ind Co Ltd | Purification of 7-aminocephalosporanic acid derivative |
| JPS60161990A (ja) * | 1984-02-02 | 1985-08-23 | Shionogi & Co Ltd | オキサセフアロスポリンの精製法 |
| GB8406218D0 (en) * | 1984-03-09 | 1984-04-11 | Glaxo Group Ltd | Process |
| EP0697396B1 (en) * | 1994-08-17 | 1999-04-14 | General Electric Company | Adsorption process for amine or amine salt recovery from aqueous brine solutions |
| JPH10101679A (ja) * | 1996-10-02 | 1998-04-21 | Otsuka Chem Co Ltd | セファゾリンの製造法 |
| CA2292618C (en) * | 1997-06-04 | 2007-07-31 | Biochemie Gesellschaft M.B.H. | Improved precipitation process of 7-aminocephalosporanic acid (7-aca) |
| CN104610282B (zh) * | 2015-02-14 | 2017-03-15 | 石药集团中诺药业（石家庄）有限公司 | 一种头孢唑啉酸的提纯方法 |
-
1974
- 1974-12-31 BE BE152080A patent/BE824028A/xx not_active IP Right Cessation
-
1975
- 1975-01-20 DE DE19752502097 patent/DE2502097A1/de not_active Withdrawn
- 1975-01-20 IE IE10375A patent/IE40481B1/xx unknown
- 1975-01-20 GB GB238275A patent/GB1472966A/en not_active Expired
- 1975-01-20 FR FR7501678A patent/FR2258388B1/fr not_active Expired
- 1975-01-21 ES ES433995A patent/ES433995A1/es not_active Expired
- 1975-01-22 CH CH83375A patent/CH613971A5/xx not_active IP Right Cessation
- 1975-01-22 JP JP50010125A patent/JPS50106996A/ja active Pending
- 1975-01-23 NL NL7500805A patent/NL7500805A/xx not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| NL7500805A (nl) | 1975-07-25 |
| IE40481L (en) | 1975-07-23 |
| CH613971A5 (en) | 1979-10-31 |
| FR2258388A1 (xx) | 1975-08-18 |
| GB1472966A (en) | 1977-05-11 |
| DE2502097A1 (de) | 1975-07-24 |
| FR2258388B1 (xx) | 1978-07-07 |
| JPS50106996A (xx) | 1975-08-22 |
| ES433995A1 (es) | 1976-11-16 |
| IE40481B1 (en) | 1979-06-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RE | Patent lapsed |
Owner name: SMITHKLINE CORP. Effective date: 19881231 |