GB1471564A - Direct compression tabletting composition and tablets produced therefrom - Google Patents
Direct compression tabletting composition and tablets produced therefromInfo
- Publication number
- GB1471564A GB1471564A GB4158774A GB4158774A GB1471564A GB 1471564 A GB1471564 A GB 1471564A GB 4158774 A GB4158774 A GB 4158774A GB 4158774 A GB4158774 A GB 4158774A GB 1471564 A GB1471564 A GB 1471564A
- Authority
- GB
- United Kingdom
- Prior art keywords
- mixture
- maltodextrin
- weight
- vehicle
- direct compression
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000000203 mixture Substances 0.000 title abstract 5
- 238000007907 direct compression Methods 0.000 title abstract 2
- 229920002774 Maltodextrin Polymers 0.000 abstract 3
- 239000005913 Maltodextrin Substances 0.000 abstract 3
- 229940035034 maltodextrin Drugs 0.000 abstract 3
- RZVAJINKPMORJF-UHFFFAOYSA-N Acetaminophen Chemical compound CC(=O)NC1=CC=C(O)C=C1 RZVAJINKPMORJF-UHFFFAOYSA-N 0.000 abstract 2
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 abstract 2
- 239000003826 tablet Substances 0.000 abstract 2
- ZAKOWWREFLAJOT-CEFNRUSXSA-N D-alpha-tocopherylacetate Chemical compound CC(=O)OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C ZAKOWWREFLAJOT-CEFNRUSXSA-N 0.000 abstract 1
- 229920002245 Dextrose equivalent Polymers 0.000 abstract 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 1
- UIIMBOGNXHQVGW-DEQYMQKBSA-M Sodium bicarbonate-14C Chemical compound [Na+].O[14C]([O-])=O UIIMBOGNXHQVGW-DEQYMQKBSA-M 0.000 abstract 1
- ABBQHOQBGMUPJH-UHFFFAOYSA-M Sodium salicylate Chemical compound [Na+].OC1=CC=CC=C1C([O-])=O ABBQHOQBGMUPJH-UHFFFAOYSA-M 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- WNROFYMDJYEPJX-UHFFFAOYSA-K aluminium hydroxide Chemical compound [OH-].[OH-].[OH-].[Al+3] WNROFYMDJYEPJX-UHFFFAOYSA-K 0.000 abstract 1
- 229910021502 aluminium hydroxide Inorganic materials 0.000 abstract 1
- 229940024545 aluminum hydroxide Drugs 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 229960005070 ascorbic acid Drugs 0.000 abstract 1
- 235000010323 ascorbic acid Nutrition 0.000 abstract 1
- 239000011668 ascorbic acid Substances 0.000 abstract 1
- MKJXYGKVIBWPFZ-UHFFFAOYSA-L calcium lactate Chemical compound [Ca+2].CC(O)C([O-])=O.CC(O)C([O-])=O MKJXYGKVIBWPFZ-UHFFFAOYSA-L 0.000 abstract 1
- 239000001527 calcium lactate Substances 0.000 abstract 1
- 229960002401 calcium lactate Drugs 0.000 abstract 1
- 235000011086 calcium lactate Nutrition 0.000 abstract 1
- 239000007891 compressed tablet Substances 0.000 abstract 1
- ZAKOWWREFLAJOT-UHFFFAOYSA-N d-alpha-Tocopheryl acetate Natural products CC(=O)OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C ZAKOWWREFLAJOT-UHFFFAOYSA-N 0.000 abstract 1
- 239000008121 dextrose Substances 0.000 abstract 1
- GXGAKHNRMVGRPK-UHFFFAOYSA-N dimagnesium;dioxido-bis[[oxido(oxo)silyl]oxy]silane Chemical compound [Mg+2].[Mg+2].[O-][Si](=O)O[Si]([O-])([O-])O[Si]([O-])=O GXGAKHNRMVGRPK-UHFFFAOYSA-N 0.000 abstract 1
- 238000001035 drying Methods 0.000 abstract 1
- 239000011790 ferrous sulphate Substances 0.000 abstract 1
- 235000003891 ferrous sulphate Nutrition 0.000 abstract 1
- 238000005469 granulation Methods 0.000 abstract 1
- 230000003179 granulation Effects 0.000 abstract 1
- 239000000391 magnesium silicate Substances 0.000 abstract 1
- 229940099273 magnesium trisilicate Drugs 0.000 abstract 1
- 229910000386 magnesium trisilicate Inorganic materials 0.000 abstract 1
- 235000019793 magnesium trisilicate Nutrition 0.000 abstract 1
- 229960005489 paracetamol Drugs 0.000 abstract 1
- 229960004025 sodium salicylate Drugs 0.000 abstract 1
- 239000008247 solid mixture Substances 0.000 abstract 1
- 229940042585 tocopherol acetate Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C13—SUGAR INDUSTRY
- C13B—PRODUCTION OF SUCROSE; APPARATUS SPECIALLY ADAPTED THEREFOR
- C13B50/00—Sugar products, e.g. powdered, lump or liquid sugar; Working-up of sugar
- C13B50/002—Addition of chemicals or other foodstuffs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
-
- C—CHEMISTRY; METALLURGY
- C13—SUGAR INDUSTRY
- C13B—PRODUCTION OF SUCROSE; APPARATUS SPECIALLY ADAPTED THEREFOR
- C13B50/00—Sugar products, e.g. powdered, lump or liquid sugar; Working-up of sugar
- C13B50/02—Sugar products, e.g. powdered, lump or liquid sugar; Working-up of sugar formed by moulding sugar
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Food Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US401322A US3873694A (en) | 1973-09-27 | 1973-09-27 | Direct compression tabletting composition and pharmaceutical tablets produced therefrom |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1471564A true GB1471564A (en) | 1977-04-27 |
Family
ID=23587269
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB4158774A Expired GB1471564A (en) | 1973-09-27 | 1974-09-24 | Direct compression tabletting composition and tablets produced therefrom |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US3873694A (https=) |
| JP (1) | JPS5058219A (https=) |
| ES (1) | ES430431A1 (https=) |
| GB (1) | GB1471564A (https=) |
| MY (1) | MY7800034A (https=) |
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2822324C3 (de) * | 1978-05-22 | 1981-02-26 | Basf Ag, 6700 Ludwigshafen | Herstellung von Vitamin-E-Trockenpulver |
| US4349542A (en) * | 1979-06-08 | 1982-09-14 | National Research Development Corporation | Mixture containing active ingredient and dendritic crystalline sugar for tableting |
| SE7905972L (sv) * | 1979-07-09 | 1981-01-10 | Haessle Ab | Forfarande for framstellning av magsyraneutraliserande medel, magsyraneutraliserande medel, samt metod for behandling av hyperaciditet och dermed relaterande sjukdomstillstand |
| AR226763A1 (es) * | 1980-12-22 | 1982-08-13 | Monsanto Co | Metodo de preparacion de una granulacion analgesica de acetaminofeno |
| IE55579B1 (en) * | 1982-07-06 | 1990-11-07 | Sterwin Ag | Processes for preparing tablets by a modified'wet-granulation'technique |
| US4495177A (en) * | 1983-01-17 | 1985-01-22 | Shaklee Corporation | Gel tableting agent |
| US4643894A (en) * | 1984-07-24 | 1987-02-17 | Colorcon, Inc. | Maltodextrin coating |
| US4639458A (en) * | 1985-01-22 | 1987-01-27 | Merck & Co., Inc. | Tablet and formulation |
| US4684534A (en) * | 1985-02-19 | 1987-08-04 | Dynagram Corporation Of America | Quick-liquifying, chewable tablet |
| US4711894A (en) * | 1986-01-16 | 1987-12-08 | Henkel Corporation | Stabilized tocopherol in dry, particulate, free-flowing form |
| FR2613619B1 (fr) * | 1987-04-07 | 1993-10-15 | Recherche Informatique Pharmacie | Medicaments, produits dietetiques ou produits d'hygiene sous forme de compositions pulverulentes obtenues par adsorption de principes actifs sur un sucre a dissolution rapide |
| US4894236A (en) * | 1988-01-12 | 1990-01-16 | Choong-Gook Jang | Direct compression tablet binders for acetaminophen |
| US5047246A (en) * | 1988-09-09 | 1991-09-10 | Bristol-Myers Company | Direct compression cyclophosphamide tablet |
| NZ232346A (en) * | 1989-02-07 | 1992-03-26 | Duphar Int Res | Effervescent oral rehydration solution comprising saccharides, amino acids and bicarbonate salts |
| US5198228A (en) * | 1989-09-14 | 1993-03-30 | Hoechst-Roussel Pharmaceuticals Inc. | Direct dry compressible acetaminophen tablet |
| US5130140A (en) * | 1989-09-14 | 1992-07-14 | Hoeschst-Roussel Pharmaceuticals Inc. | Method of making direct dry compressible acetaminophen composition |
| US5037658A (en) * | 1989-09-14 | 1991-08-06 | Hoechst-Roussel Pharmaceuticals, Inc. | Direct dry compressible acetaminophen composition |
| DK0527153T3 (da) * | 1990-04-04 | 1996-11-25 | Berwind Pharma Service | Vandige filmovertræk af maltodextrin og cellulosepolymerer |
| JP2542122B2 (ja) * | 1990-04-18 | 1996-10-09 | 旭化成工業株式会社 | 球状核、球形顆粒およびその製造方法 |
| EP0452862B1 (en) * | 1990-04-18 | 1995-07-19 | Asahi Kasei Kogyo Kabushiki Kaisha | Spherical seed cores, spherical granules and process for production thereof |
| US5531983A (en) * | 1990-10-08 | 1996-07-02 | Purac Biochem B.V. | Oral hygiene preparation |
| SE9301220D0 (sv) * | 1993-04-14 | 1993-04-14 | Kabi Pharmacia Ab | Manufacturing matrices |
| US5424289A (en) * | 1993-07-30 | 1995-06-13 | Alza Corporation | Solid formulations of therapeutic proteins for gastrointestinal delivery |
| ATE253899T1 (de) * | 1994-01-31 | 2003-11-15 | Yamanouchi Pharma Co Ltd | Intraoral löslicher formpressling und verfahren zu seiner herstellung |
| US5798388A (en) * | 1996-09-06 | 1998-08-25 | Cellular Sciences, Inc. | Method and composition for treating mammalian diseases caused by inflammatory response |
| US6080427A (en) * | 1997-04-17 | 2000-06-27 | Bristol-Myers Squibb Company | Cefadroxil monohydrate tablet formulation |
| FR2769636B1 (fr) * | 1997-10-13 | 2000-01-28 | Saint Louis Sucre Sa | Produit hydrophobe a base de saccharose |
| US6348264B1 (en) | 1998-04-27 | 2002-02-19 | Roquette Freres | Process for producing low de starch hydrolysates by nanofiltration fractionation, products obtained thereby, and use of such products |
| US6723342B1 (en) | 1999-02-08 | 2004-04-20 | Fmc Corporation | Edible coating composition |
| US6432448B1 (en) | 1999-02-08 | 2002-08-13 | Fmc Corporation | Edible coating composition |
| US6716453B1 (en) * | 1999-05-20 | 2004-04-06 | Verion, Inc. | Method for increasing the active loading of compressible composition forms |
| US6500462B1 (en) | 1999-10-29 | 2002-12-31 | Fmc Corporation | Edible MCC/PGA coating composition |
| BR0115585A (pt) | 2000-11-28 | 2005-12-13 | Fmc Corp | Composições de revestimento de pronta liberação, endurecìvel, comestìvel, seca e, úmida, forma de dosagem sólida, e, método para revestir uma forma de dosagem sólida farmacêutica ou veterinária, confeito, semente, ração animal, fertilizante, comprimido de pesticida ou alimento |
| US6932861B2 (en) * | 2000-11-28 | 2005-08-23 | Fmc Corporation | Edible PGA coating composition |
| US7282217B1 (en) | 2003-08-29 | 2007-10-16 | Kv Pharmaceutical Company | Rapidly disintegrable tablets |
| US20050143343A1 (en) * | 2003-12-30 | 2005-06-30 | Nerenberg Arnold P. | Nutritional supplement for enhancing the production and effect of natural human growth hormone |
| US20080069936A1 (en) * | 2006-09-18 | 2008-03-20 | ISON Renny | Cohesive non-free flowing sweeetener compositions containing a hygroscopic gluing agent and a desiccant |
| EP2395972A4 (en) * | 2009-02-11 | 2014-02-12 | Liangping Yu | PARTICULATE COMPOSITION AND METHOD FOR PRODUCING THE SAME |
| CN103237902A (zh) | 2010-08-13 | 2013-08-07 | Rdm企业股份有限公司 | 减少糖的颜色的方法和组合物 |
| WO2014144407A1 (en) | 2013-03-15 | 2014-09-18 | Braintree Laboratories, Inc. | Dual use oral pharmaceutical composition tablets of sulfate saltes and methods of use thereof |
| DE202015004009U1 (de) | 2015-06-09 | 2016-01-11 | Hermes Arzneimittel Gmbh | Schnell zerfallende Tabletten ohne Zerfallsbeschleuniger |
| DE202016005032U1 (de) | 2016-08-19 | 2017-02-10 | Hermes Arzneimittel Gmbh | Schnell zerfallende Efeu-Trinktabletten ohne Zerfallsbeschleuniger |
| US10143656B1 (en) | 2017-08-04 | 2018-12-04 | Braintree Laboratories, Inc. | Solid oral sulfate salt formulations for cleaning a colon and methods of using same |
| JP2023144552A (ja) * | 2022-03-28 | 2023-10-11 | 三菱商事ライフサイエンス株式会社 | 顆粒状賦形剤用結合剤、それを用いた賦形剤および錠剤、ならびに崩壊性を上昇させる方法 |
| WO2024256873A1 (en) | 2023-06-15 | 2024-12-19 | Sebela Ireland Limited | Methods of administering safe colon cleansing compositions |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3140201A (en) * | 1962-01-09 | 1964-07-07 | American Sugar | Dry pulverulent sugar products and process for producing same |
| US3169888A (en) * | 1962-03-05 | 1965-02-16 | American Sugar | Pressed crystal sugar tablet and method of manufacturing same |
| US3305447A (en) * | 1963-06-12 | 1967-02-21 | American Sugar | Tabletting sugar and method of preparing same |
| US3619292A (en) * | 1968-07-15 | 1971-11-09 | Penick & Ford Ltd | Tablets and method of forming |
| US3589909A (en) * | 1968-10-31 | 1971-06-29 | Corn Products Co | Gum confections containing dextrose and 5-15 d. e. starch hydrolysate |
| US3639168A (en) * | 1969-04-29 | 1972-02-01 | Sucrest Corp | Direct compression vehicles |
| US3627583A (en) * | 1969-04-29 | 1971-12-14 | Sucrest Corp | Direct compression vehicles |
| US3639169A (en) * | 1969-04-29 | 1972-02-01 | Sucrest Corp | Direct compression vehicles and method therefor |
| US3642535A (en) * | 1970-01-21 | 1972-02-15 | American Sugar | Tabletting sugar, method of preparing compositions containing same |
-
1973
- 1973-09-27 US US401322A patent/US3873694A/en not_active Expired - Lifetime
-
1974
- 1974-09-24 GB GB4158774A patent/GB1471564A/en not_active Expired
- 1974-09-26 ES ES430431A patent/ES430431A1/es not_active Expired
- 1974-09-27 JP JP49110653A patent/JPS5058219A/ja active Pending
-
1978
- 1978-12-30 MY MY34/78A patent/MY7800034A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US3873694A (en) | 1975-03-25 |
| MY7800034A (en) | 1978-12-31 |
| ES430431A1 (es) | 1976-10-01 |
| JPS5058219A (https=) | 1975-05-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |