GB1468347A - Aminoindanes - Google Patents
AminoindanesInfo
- Publication number
- GB1468347A GB1468347A GB1030473A GB1030473A GB1468347A GB 1468347 A GB1468347 A GB 1468347A GB 1030473 A GB1030473 A GB 1030473A GB 1030473 A GB1030473 A GB 1030473A GB 1468347 A GB1468347 A GB 1468347A
- Authority
- GB
- United Kingdom
- Prior art keywords
- aminoindane
- phenyl
- aminopropyl
- substituted
- aminoindanes
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- XJEVHMGJSYVQBQ-UHFFFAOYSA-N 2,3-dihydro-1h-inden-1-amine Chemical class C1=CC=C2C(N)CCC2=C1 XJEVHMGJSYVQBQ-UHFFFAOYSA-N 0.000 title abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- IPHLKNASBKBUSH-UHFFFAOYSA-N 1-methylsulfonyl-2,3-dihydro-1H-indene Chemical compound CS(=O)(=O)C1CCc2ccccc12 IPHLKNASBKBUSH-UHFFFAOYSA-N 0.000 abstract 1
- 125000004105 2-pyridyl group Chemical group N1=C([*])C([H])=C([H])C([H])=C1[H] 0.000 abstract 1
- UZFMOKQJFYMBGY-UHFFFAOYSA-N 4-hydroxy-TEMPO Chemical compound CC1(C)CC(O)CC(C)(C)N1[O] UZFMOKQJFYMBGY-UHFFFAOYSA-N 0.000 abstract 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 1
- HPTMXLNJFKITJR-UHFFFAOYSA-N N'-(2,3-dihydro-1H-inden-2-yl)-N'-phenyl-N-propan-2-ylpropane-1,3-diamine Chemical compound C1(=CC=CC=C1)N(C1CC2=CC=CC=C2C1)CCCNC(C)C HPTMXLNJFKITJR-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000000304 alkynyl group Chemical group 0.000 abstract 1
- 125000004103 aminoalkyl group Chemical group 0.000 abstract 1
- 206010003119 arrhythmia Diseases 0.000 abstract 1
- 230000006793 arrhythmia Effects 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- -1 diethylaminobutyryl Chemical group 0.000 abstract 1
- 125000002768 hydroxyalkyl group Chemical group 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 238000010561 standard procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (24)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1030473A GB1468347A (en) | 1973-03-02 | 1973-03-02 | Aminoindanes |
| AR252609A AR204526A1 (es) | 1973-03-02 | 1974-01-01 | Procedimiento para preparar nuevos derivados de 2-aminoindano |
| CA193,354A CA1036164A (en) | 1973-03-02 | 1974-02-25 | Derivatives of 2-amino-indane, the preparation and use thereof |
| ZA00741232A ZA741232B (en) | 1973-03-02 | 1974-02-25 | New derivatives of 2-aminoindane, the preparation and use thereof |
| AU66070/74A AU485528B2 (en) | 1973-03-02 | 1974-02-27 | New derivatives of 2-aminoindane the preparation and use thereof |
| IL44320A IL44320A (en) | 1973-03-02 | 1974-02-28 | Derivatives of 2-aminoindane their preparation and pharmaceutical compositions containing them |
| NL7402830A NL7402830A (enrdf_load_html_response) | 1973-03-02 | 1974-03-01 | |
| JP2470474A JPS547789B2 (enrdf_load_html_response) | 1973-03-02 | 1974-03-01 | |
| CH257877A CH593910A5 (enrdf_load_html_response) | 1973-03-02 | 1974-03-01 | |
| CH257777A CH605619A5 (enrdf_load_html_response) | 1973-03-02 | 1974-03-01 | |
| BE141546A BE811762A (fr) | 1973-03-02 | 1974-03-01 | Nouveaux derives du 2-aminoindane |
| ES423789A ES423789A1 (es) | 1973-03-02 | 1974-03-01 | Un procedimiento para preparar nuevos derivados de 2-ami- noindano. |
| FR7407092A FR2219787B1 (enrdf_load_html_response) | 1973-03-02 | 1974-03-01 | |
| CH297474A CH593909A5 (enrdf_load_html_response) | 1973-03-02 | 1974-03-01 | |
| HUCI1459A HU169840B (enrdf_load_html_response) | 1973-03-02 | 1974-03-01 | |
| DE2409791A DE2409791C3 (de) | 1973-03-02 | 1974-03-01 | Derivate von 2-Aminoindan und'sie enthaltende Arzneimittel |
| AT170774A AT333742B (de) | 1973-03-02 | 1974-03-01 | Verfahren zur herstellung neuer 2-aminoindan-derivate |
| LU69535A LU69535A1 (enrdf_load_html_response) | 1973-03-02 | 1974-03-01 | |
| MX579774U MX5318E (es) | 1973-03-02 | 1974-03-04 | Procedimiento para preparar derivados de 2-aminoindano |
| DD176932A DD112262A5 (enrdf_load_html_response) | 1973-03-02 | 1974-03-04 | |
| DD181958A DD113999A5 (enrdf_load_html_response) | 1973-03-02 | 1974-03-04 | |
| AR260956A AR206652A1 (es) | 1973-03-02 | 1975-01-01 | Procedimiento para preparar nuevos derivados de n-amino-alquil-2-aminoindano |
| AR260957A AR206653A1 (es) | 1973-03-02 | 1975-01-01 | Procedimiento para preparar nuevos derivados de n-aminoalquil-2-amino-indano |
| AT359175A AT336017B (de) | 1973-03-02 | 1975-05-12 | Verfahren zur herstellung neuer 2-aminoindan-derivate und ihrer saureadditionssalze |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1030473A GB1468347A (en) | 1973-03-02 | 1973-03-02 | Aminoindanes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1468347A true GB1468347A (en) | 1977-03-23 |
Family
ID=9965409
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1030473A Expired GB1468347A (en) | 1973-03-02 | 1973-03-02 | Aminoindanes |
Country Status (16)
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1185267A4 (en) * | 1999-06-10 | 2003-09-03 | Bridge Pharma Inc | DERMAL ARNESTHETICS |
| EP1658847A3 (en) * | 1999-06-10 | 2006-07-26 | Bridge Pharma, Inc. | Indane derivatives as dermal anesthetic agents |
| US7592458B2 (en) | 2006-07-21 | 2009-09-22 | Wright George E | Dermal anesthetic compounds and pharmaceutical compositions for inducing local anesthesia and mitigating neuropathic pain |
| US7718674B2 (en) | 2004-09-27 | 2010-05-18 | Bridge Pharma, Inc. | Methods of relieving neuropathic pain with the S-isomer of 2-{2[N-(2-indanyl)-N-phenylamino]ethyl}piperidine |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE760018A (fr) * | 1969-12-19 | 1971-06-08 | Christiaens Sa A | Nouveau derives du 2-amino-indane, leur preparation et leur utilisation |
| JPS5216322B2 (enrdf_load_html_response) * | 1972-06-22 | 1977-05-09 | ||
| JPS4922702A (enrdf_load_html_response) * | 1972-06-22 | 1974-02-28 |
-
1973
- 1973-03-02 GB GB1030473A patent/GB1468347A/en not_active Expired
-
1974
- 1974-01-01 AR AR252609A patent/AR204526A1/es active
- 1974-02-25 CA CA193,354A patent/CA1036164A/en not_active Expired
- 1974-02-25 ZA ZA00741232A patent/ZA741232B/xx unknown
- 1974-02-28 IL IL44320A patent/IL44320A/en unknown
- 1974-03-01 ES ES423789A patent/ES423789A1/es not_active Expired
- 1974-03-01 BE BE141546A patent/BE811762A/xx unknown
- 1974-03-01 CH CH257877A patent/CH593910A5/xx not_active IP Right Cessation
- 1974-03-01 HU HUCI1459A patent/HU169840B/hu unknown
- 1974-03-01 CH CH257777A patent/CH605619A5/xx not_active IP Right Cessation
- 1974-03-01 FR FR7407092A patent/FR2219787B1/fr not_active Expired
- 1974-03-01 AT AT170774A patent/AT333742B/de not_active IP Right Cessation
- 1974-03-01 NL NL7402830A patent/NL7402830A/xx not_active Application Discontinuation
- 1974-03-01 DE DE2409791A patent/DE2409791C3/de not_active Expired
- 1974-03-01 CH CH297474A patent/CH593909A5/xx not_active IP Right Cessation
- 1974-03-01 LU LU69535A patent/LU69535A1/xx unknown
- 1974-03-01 JP JP2470474A patent/JPS547789B2/ja not_active Expired
- 1974-03-04 DD DD176932A patent/DD112262A5/xx unknown
- 1974-03-04 DD DD181958A patent/DD113999A5/xx unknown
-
1975
- 1975-01-01 AR AR260957A patent/AR206653A1/es active
- 1975-01-01 AR AR260956A patent/AR206652A1/es active
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1185267A4 (en) * | 1999-06-10 | 2003-09-03 | Bridge Pharma Inc | DERMAL ARNESTHETICS |
| EP1658847A3 (en) * | 1999-06-10 | 2006-07-26 | Bridge Pharma, Inc. | Indane derivatives as dermal anesthetic agents |
| US7718674B2 (en) | 2004-09-27 | 2010-05-18 | Bridge Pharma, Inc. | Methods of relieving neuropathic pain with the S-isomer of 2-{2[N-(2-indanyl)-N-phenylamino]ethyl}piperidine |
| US7592458B2 (en) | 2006-07-21 | 2009-09-22 | Wright George E | Dermal anesthetic compounds and pharmaceutical compositions for inducing local anesthesia and mitigating neuropathic pain |
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |