GB1451151A - Chromanols and derivatives thereof - Google Patents

Chromanols and derivatives thereof

Info

Publication number
GB1451151A
GB1451151A GB1323174A GB1323174A GB1451151A GB 1451151 A GB1451151 A GB 1451151A GB 1323174 A GB1323174 A GB 1323174A GB 1323174 A GB1323174 A GB 1323174A GB 1451151 A GB1451151 A GB 1451151A
Authority
GB
United Kingdom
Prior art keywords
chromanols
hydrates
ethers
image
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1323174A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Priority to GB1323174A priority Critical patent/GB1451151A/en
Priority to US05/504,087 priority patent/US3960880A/en
Priority to IE443/75A priority patent/IE40859B1/en
Priority to ZA00751396A priority patent/ZA751396B/en
Priority to FI750732A priority patent/FI750732A/fi
Priority to NL7503368A priority patent/NL7503368A/en
Priority to FR7508882A priority patent/FR2265372B1/fr
Priority to BE154633A priority patent/BE827030A/en
Priority to SE7503406A priority patent/SE7503406L/xx
Priority to ES436029A priority patent/ES436029A1/en
Priority to DE19752513220 priority patent/DE2513220A1/en
Priority to CH380875A priority patent/CH612965A5/en
Priority to DK132775A priority patent/DK132775A/da
Priority to AT232375A priority patent/AT345825B/en
Priority to JP50036521A priority patent/JPS50135085A/ja
Priority to AU80466/75A priority patent/AU8046675A/en
Publication of GB1451151A publication Critical patent/GB1451151A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrane Compounds (AREA)

Abstract

Chromanols with good antihypertensive effects and lower toxicity and with the following formula are prepared <IMAGE> in which R1 is a straight-chain alkyl radical which is optionally alpha -substituted by 1 or 2 methyl groups and has 5-8 C atoms, as well as their salts, ethers, acyl derivatives and hydrates. This entails reducing a corresponding compound of the formula VI or its phenol salts or ethers <IMAGE> in which B<(-)> is defined as anion, preferably with sodium borohydride. Acylation or hydration of the compound of the formula III results in the corresponding acyl derivatives or hydrates.
GB1323174A 1974-03-26 1974-03-26 Chromanols and derivatives thereof Expired GB1451151A (en)

Priority Applications (16)

Application Number Priority Date Filing Date Title
GB1323174A GB1451151A (en) 1974-03-26 1974-03-26 Chromanols and derivatives thereof
US05/504,087 US3960880A (en) 1974-03-26 1974-09-09 Tetrahydropyrid-4-yl-chroman-5-ol derivatives
IE443/75A IE40859B1 (en) 1974-03-26 1975-03-03 Chromanols and derivatives thereof
ZA00751396A ZA751396B (en) 1974-03-26 1975-03-07 Chromanols
FI750732A FI750732A (en) 1974-03-26 1975-03-13
NL7503368A NL7503368A (en) 1974-03-26 1975-03-20 METHOD OF PREPARING A MEDICINAL PRODUCT WITH BLOOD PRESSURE-LOWERING ACTION, FORMED MEDICINAL PRODUCT OBTAINED BY THIS METHOD AND PROCESS FOR PREPARING OLD CHROMAN-5-OLD USED IN THE MEDICINAL PRODUCT.
FR7508882A FR2265372B1 (en) 1974-03-26 1975-03-21
BE154633A BE827030A (en) 1974-03-26 1975-03-21 CHROMANOLS
SE7503406A SE7503406L (en) 1974-03-26 1975-03-24
ES436029A ES436029A1 (en) 1974-03-26 1975-03-25 A procedure for the preparation of chromanols. (Machine-translation by Google Translate, not legally binding)
DE19752513220 DE2513220A1 (en) 1974-03-26 1975-03-25 CHROMANOLS, THE PROCESS FOR THEIR MANUFACTURING AND MEDICINAL PREPARATIONS CONTAINING THESE COMPOUNDS
CH380875A CH612965A5 (en) 1974-03-26 1975-03-25 Process for the preparation of chromanols and their ethers
DK132775A DK132775A (en) 1974-03-26 1975-03-26
AT232375A AT345825B (en) 1974-03-26 1975-03-26 PROCESS FOR THE PREPARATION OF NEW CHROMANOLS AND THEIR SALTS, HYDRATES, ETHERS AND ACYLDER DERIVATIVES
JP50036521A JPS50135085A (en) 1974-03-26 1975-03-26
AU80466/75A AU8046675A (en) 1974-03-26 1975-04-23 Chromanols

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB1323174A GB1451151A (en) 1974-03-26 1974-03-26 Chromanols and derivatives thereof
GB2963874 1974-07-04

Publications (1)

Publication Number Publication Date
GB1451151A true GB1451151A (en) 1976-09-29

Family

ID=26249640

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1323174A Expired GB1451151A (en) 1974-03-26 1974-03-26 Chromanols and derivatives thereof

Country Status (12)

Country Link
JP (1) JPS50135085A (en)
AT (1) AT345825B (en)
AU (1) AU8046675A (en)
CH (1) CH612965A5 (en)
DE (1) DE2513220A1 (en)
DK (1) DK132775A (en)
FI (1) FI750732A (en)
FR (1) FR2265372B1 (en)
GB (1) GB1451151A (en)
IE (1) IE40859B1 (en)
NL (1) NL7503368A (en)
SE (1) SE7503406L (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6336682B1 (en) * 2000-09-05 2002-01-08 M. Scot Rosko Child vehicle seat with shoulder strap guide

Also Published As

Publication number Publication date
JPS50135085A (en) 1975-10-25
IE40859B1 (en) 1979-08-29
CH612965A5 (en) 1979-08-31
IE40859L (en) 1975-09-26
DK132775A (en) 1975-09-27
FI750732A (en) 1975-09-27
FR2265372A1 (en) 1975-10-24
AT345825B (en) 1978-10-10
FR2265372B1 (en) 1978-07-28
AU8046675A (en) 1976-10-28
DE2513220A1 (en) 1975-10-02
NL7503368A (en) 1975-09-30
SE7503406L (en) 1975-09-29
ATA232375A (en) 1978-02-15

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee