GB1453394A - Phenylpropylamine derivatives - Google Patents

Phenylpropylamine derivatives

Info

Publication number
GB1453394A
GB1453394A GB1207274A GB1207274A GB1453394A GB 1453394 A GB1453394 A GB 1453394A GB 1207274 A GB1207274 A GB 1207274A GB 1207274 A GB1207274 A GB 1207274A GB 1453394 A GB1453394 A GB 1453394A
Authority
GB
United Kingdom
Prior art keywords
radical
carbon atoms
alkyl
compounds
atoms
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1207274A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP3209173A external-priority patent/JPS49117437A/ja
Priority claimed from JP3209073A external-priority patent/JPS49117433A/ja
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of GB1453394A publication Critical patent/GB1453394A/en
Expired legal-status Critical Current

Links

Landscapes

  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Compounds of the formula <IMAGE> in which R<1> and R<2> are identical or different and represent hydrogen atoms, hydroxyl groups or methoxy radicals, R<3> is a phenyl radical and R<4> is an alkyl radical having 1 to 6 carbon atoms, R<5> represents an alkyl radical having 1 to 6 carbon atoms or a hydroxyalkyl radical having 2 or 3 carbon atoms and R<6> denotes a hydrogen atom, an alkyl radical having 1 to 6 carbon atoms or a hydroxyalkyl radical having 2 or 3 carbon atoms, with the proviso that in cases in which R<1> and R<2> are hydrogen atoms, R<4> is not a methyl radical, R<5> is not an alkyl group and R<6> is neither a hydrogen atom nor an alkyl group, are obtained by alkylation of corresponding 3-phenylpropylamines. The compounds and their salts with acids are distinguished, with very low toxicity, by potent analgesic properties; they also have an antipyretic and cough-relieving action.
GB1207274A 1973-03-19 1974-03-19 Phenylpropylamine derivatives Expired GB1453394A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP3209173A JPS49117437A (en) 1973-03-19 1973-03-19
JP3209073A JPS49117433A (en) 1973-03-19 1973-03-19

Publications (1)

Publication Number Publication Date
GB1453394A true GB1453394A (en) 1976-10-20

Family

ID=26370606

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1207274A Expired GB1453394A (en) 1973-03-19 1974-03-19 Phenylpropylamine derivatives

Country Status (5)

Country Link
CH (1) CH609324A5 (en)
DE (1) DE2412798A1 (en)
FR (1) FR2222355B1 (en)
GB (1) GB1453394A (en)
NL (1) NL7403348A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1633695A2 (en) * 2003-05-23 2006-03-15 Bridge Pharma, Inc. Smooth muscle spasmolytic agents

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0069063B1 (en) * 1981-06-19 1986-01-22 Ciba-Geigy Ag Aminoalkyl-substituted aromatic or heterocyclic compounds and process for their preparation
DE3360926D1 (en) * 1982-06-16 1985-11-07 Ciba Geigy Ag Hydroquinone ethers and a process for preparing them
DE4426245A1 (en) 1994-07-23 1996-02-22 Gruenenthal Gmbh 1-phenyl-3-dimethylamino-propane compounds with pharmacological activity

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1633695A2 (en) * 2003-05-23 2006-03-15 Bridge Pharma, Inc. Smooth muscle spasmolytic agents
EP1633695A4 (en) * 2003-05-23 2007-12-12 Bridge Pharma Inc Smooth muscle spasmolytic agents

Also Published As

Publication number Publication date
FR2222355A1 (en) 1974-10-18
CH609324A5 (en) 1979-02-28
NL7403348A (en) 1974-09-23
DE2412798A1 (en) 1974-09-26
FR2222355B1 (en) 1977-11-04

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee