GB1444717A - Bicycloalkyl derivatives - Google Patents

Bicycloalkyl derivatives

Info

Publication number
GB1444717A
GB1444717A GB5093172A GB5093172A GB1444717A GB 1444717 A GB1444717 A GB 1444717A GB 5093172 A GB5093172 A GB 5093172A GB 5093172 A GB5093172 A GB 5093172A GB 1444717 A GB1444717 A GB 1444717A
Authority
GB
United Kingdom
Prior art keywords
oct
trans
alkyl
acid
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB5093172A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lilly Industries Ltd
Original Assignee
Lilly Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Industries Ltd filed Critical Lilly Industries Ltd
Priority to GB5093172A priority Critical patent/GB1444717A/en
Priority to IE1824/73A priority patent/IE38375B1/xx
Priority to IL43470A priority patent/IL43470A/en
Priority to SE7314756A priority patent/SE419980B/xx
Priority to FR7338821A priority patent/FR2205324B1/fr
Priority to BE137315A priority patent/BE806808A/xx
Priority to NLAANVRAGE7315031,A priority patent/NL182143C/xx
Priority to JP48123891A priority patent/JPS5747664B2/ja
Priority to DK593573AA priority patent/DK142111B/da
Priority to DE2354931A priority patent/DE2354931C2/de
Priority to CH1542273A priority patent/CH588440A5/xx
Priority to US05/603,230 priority patent/US3980785A/en
Publication of GB1444717A publication Critical patent/GB1444717A/en
Priority to JP57018087A priority patent/JPS5936973B2/ja
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/41—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by hydrogenolysis or reduction of carboxylic groups or functional derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/44—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by —CHO groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C247/00—Compounds containing azido groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/62—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by hydrogenation of carbon-to-carbon double or triple bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00—Compounds having —CHO groups
    • C07C47/20—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms
    • C07C47/235—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing six-membered aromatic rings and other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00—Compounds having —CHO groups
    • C07C47/38—Unsaturated compounds having —CHO groups bound to carbon atoms of rings other than six—membered aromatic rings
    • C07C47/453—Unsaturated compounds having —CHO groups bound to carbon atoms of rings other than six—membered aromatic rings containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00—Compounds having —CHO groups
    • C07C47/38—Unsaturated compounds having —CHO groups bound to carbon atoms of rings other than six—membered aromatic rings
    • C07C47/457—Unsaturated compounds having —CHO groups bound to carbon atoms of rings other than six—membered aromatic rings containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C53/00—Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen
    • C07C53/132—Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen containing rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/46—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings and other rings, e.g. cyclohexylphenylacetic acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
GB5093172A 1972-11-04 1972-11-04 Bicycloalkyl derivatives Expired GB1444717A (en)

Priority Applications (13)

Application Number Priority Date Filing Date Title
GB5093172A GB1444717A (en) 1972-11-04 1972-11-04 Bicycloalkyl derivatives
IE1824/73A IE38375B1 (en) 1972-11-04 1973-10-12 Bicycloalkyl derivatives
IL43470A IL43470A (en) 1972-11-04 1973-10-23 2-phenylbicyclo(2,2,2)octane derivatives,their preparation and pharmaceutical compositions containing them
SE7314756A SE419980B (sv) 1972-11-04 1973-10-30 Forfarande for framstellning av eventuellt substituerade 2-fenyl-bicyklo /2,2,2/okt-3-ylalkylaminer
FR7338821A FR2205324B1 (ru) 1972-11-04 1973-10-31
BE137315A BE806808A (fr) 1972-11-04 1973-10-31 Derives de bicycloalkyle
NLAANVRAGE7315031,A NL182143C (nl) 1972-11-04 1973-11-01 Werkwijze voor de bereiding van farmaceutisch werkzame, op de 2- en 3-posities gesubstitueerde, bicyclo-(2,2,2)-octaanderivaten, werkwijze voor de bereiding van een geneesmiddel, dat een dergelijke verbinding bevat, alsmede therapeutische voorwerpen op basis van een dergelijke verbinding.
JP48123891A JPS5747664B2 (ru) 1972-11-04 1973-11-02
DK593573AA DK142111B (da) 1972-11-04 1973-11-02 Analogifremgangsmåde til fremstilling af bicyclo(2,2,2)-octylaminderivater eller syreadditionssalte deraf.
DE2354931A DE2354931C2 (de) 1972-11-04 1973-11-02 trans-2-Phenylbicyclooctan-Verbindungen, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Zubereitungen
CH1542273A CH588440A5 (ru) 1972-11-04 1973-11-02
US05/603,230 US3980785A (en) 1972-11-04 1975-08-11 Secondary and tertiary-2-phenylbicyclo[2,2,2]oct-3-yl alkylamines and composition thereof
JP57018087A JPS5936973B2 (ja) 1972-11-04 1982-02-05 ビシクロアルキル誘導体

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB5093172A GB1444717A (en) 1972-11-04 1972-11-04 Bicycloalkyl derivatives

Publications (1)

Publication Number Publication Date
GB1444717A true GB1444717A (en) 1976-08-04

Family

ID=10457988

Family Applications (1)

Application Number Title Priority Date Filing Date
GB5093172A Expired GB1444717A (en) 1972-11-04 1972-11-04 Bicycloalkyl derivatives

Country Status (11)

Country Link
JP (2) JPS5747664B2 (ru)
BE (1) BE806808A (ru)
CH (1) CH588440A5 (ru)
DE (1) DE2354931C2 (ru)
DK (1) DK142111B (ru)
FR (1) FR2205324B1 (ru)
GB (1) GB1444717A (ru)
IE (1) IE38375B1 (ru)
IL (1) IL43470A (ru)
NL (1) NL182143C (ru)
SE (1) SE419980B (ru)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002028815A1 (en) * 2000-10-04 2002-04-11 Eli Lilly And Company Pharmaceutical compounds

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1549174A (en) * 1975-05-08 1979-08-01 Lilly Industries Ltd Amine derivatives
GB1551035A (en) * 1975-07-24 1979-08-22 Lilly Industries Ltd Derivatives of bicyclo (2,2,2)oct-3-ylmethylamine
US4215074A (en) * 1978-07-15 1980-07-29 Lilly Industries Limited Process for preparing cis-bicyclooctylamines

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1468808A1 (de) * 1965-04-21 1969-04-17 Du Pont Verfahren zur Herstellung von substituierten Phenylbicyclo-(2,2,2)-octanen

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002028815A1 (en) * 2000-10-04 2002-04-11 Eli Lilly And Company Pharmaceutical compounds

Also Published As

Publication number Publication date
IL43470A (en) 1976-08-31
CH588440A5 (ru) 1977-05-31
JPS57171941A (en) 1982-10-22
SE419980B (sv) 1981-09-07
BE806808A (fr) 1974-04-30
IE38375L (en) 1974-05-04
JPS5747664B2 (ru) 1982-10-12
NL7315031A (ru) 1974-05-07
DK142111B (da) 1980-09-01
NL182143B (nl) 1987-08-17
FR2205324B1 (ru) 1976-05-14
FR2205324A1 (ru) 1974-05-31
IE38375B1 (en) 1978-03-01
DK142111C (ru) 1981-02-02
DE2354931C2 (de) 1983-12-08
IL43470A0 (en) 1974-01-14
JPS5936973B2 (ja) 1984-09-06
NL182143C (nl) 1988-01-18
JPS49132058A (ru) 1974-12-18
DE2354931A1 (de) 1974-05-09

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee