GB1440634A - Process for the preparation of vincamone and vincanol - Google Patents
Process for the preparation of vincamone and vincanolInfo
- Publication number
- GB1440634A GB1440634A GB5687373A GB5687373A GB1440634A GB 1440634 A GB1440634 A GB 1440634A GB 5687373 A GB5687373 A GB 5687373A GB 5687373 A GB5687373 A GB 5687373A GB 1440634 A GB1440634 A GB 1440634A
- Authority
- GB
- United Kingdom
- Prior art keywords
- vincanol
- vincamone
- mixture
- pure
- isovincanol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- WYJAPUKIYAZSEM-MOPGFXCFSA-N Eburnamonine Chemical compound C1=CC=C2C(CCN3CCC4)=C5[C@@H]3[C@]4(CC)CC(=O)N5C2=C1 WYJAPUKIYAZSEM-MOPGFXCFSA-N 0.000 title abstract 8
- HONLKDDLTAZVQV-UHFFFAOYSA-N eburnamine Natural products C1=CC=C2C(CCN3CCC4)=C5C3C4(CC)CC(O)N5C2=C1 HONLKDDLTAZVQV-UHFFFAOYSA-N 0.000 title abstract 8
- WYJAPUKIYAZSEM-UHFFFAOYSA-N rac-Eburnamonin Natural products C1=CC=C2C(CCN3CCC4)=C5C3C4(CC)CC(=O)N5C2=C1 WYJAPUKIYAZSEM-UHFFFAOYSA-N 0.000 title abstract 8
- 229960002922 vinburnine Drugs 0.000 title abstract 8
- HONLKDDLTAZVQV-UHOSZYNNSA-N vincanol Chemical compound C1=CC=C2C(CCN3CCC4)=C5[C@@H]3[C@]4(CC)C[C@H](O)N5C2=C1 HONLKDDLTAZVQV-UHOSZYNNSA-N 0.000 title abstract 8
- 229950002496 vincanol Drugs 0.000 title abstract 8
- 239000000203 mixture Substances 0.000 abstract 4
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- KMGUEILFFWDGFV-UHFFFAOYSA-N 2-benzoyl-2-benzoyloxy-3-hydroxybutanedioic acid Chemical compound C=1C=CC=CC=1C(=O)C(C(C(O)=O)O)(C(O)=O)OC(=O)C1=CC=CC=C1 KMGUEILFFWDGFV-UHFFFAOYSA-N 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 229910052987 metal hydride Inorganic materials 0.000 abstract 1
- 150000004681 metal hydrides Chemical class 0.000 abstract 1
- 239000007800 oxidant agent Substances 0.000 abstract 1
- 230000001590 oxidative effect Effects 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D461/00—Heterocyclic compounds containing indolo [3,2,1-d,e] pyrido [3,2,1,j] [1,5]-naphthyridine ring systems, e.g. vincamine
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HURI492A HU166766B (enrdf_load_stackoverflow) | 1972-12-08 | 1972-12-08 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1440634A true GB1440634A (en) | 1976-06-23 |
Family
ID=11000909
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB5687373A Expired GB1440634A (en) | 1972-12-08 | 1973-12-07 | Process for the preparation of vincamone and vincanol |
Country Status (11)
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4291038A (en) * | 1977-02-22 | 1981-09-22 | Roussel Uclaf | Cerebral vasodilating 20,21-dinoreburnamenine derivatives |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU182411B (en) * | 1981-11-03 | 1984-01-30 | Richter Gedeon Vegyeszet | Process for preparing eburnamonine derivatives |
HU187139B (en) * | 1982-06-30 | 1985-11-28 | Richter Gedeon Vegyeszet | Process for preparing new eburnan derivatives |
HU191403B (en) * | 1984-04-02 | 1987-02-27 | Richter Gedeon Vegyeszeti Gyar Rt,Hu | Process for preparing new, raceme and optically active 14-hydroxyimino-eburnane |
-
1972
- 1972-12-08 HU HURI492A patent/HU166766B/hu unknown
-
1973
- 1973-11-21 AT AT974773A patent/AT341686B/de active
- 1973-12-03 DD DD175062A patent/DD108091A5/xx unknown
- 1973-12-04 CH CH994076A patent/CH591482A5/xx not_active IP Right Cessation
- 1973-12-04 CH CH1693273A patent/CH593973A5/xx not_active IP Right Cessation
- 1973-12-05 BE BE138536A patent/BE808245A/xx not_active IP Right Cessation
- 1973-12-05 FR FR7343390A patent/FR2209757B1/fr not_active Expired
- 1973-12-06 SE SE7316516A patent/SE408646B/xx unknown
- 1973-12-07 GB GB5687373A patent/GB1440634A/en not_active Expired
- 1973-12-07 SU SU731976298A patent/SU629883A3/ru active
- 1973-12-07 PL PL1973167132A patent/PL94163B1/pl unknown
- 1973-12-08 JP JP48137274A patent/JPS5147720B2/ja not_active Expired
-
1976
- 1976-10-05 SU SU762406242A patent/SU589923A3/ru active
-
1977
- 1977-03-02 SE SE7702331A patent/SE415884B/xx unknown
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4291038A (en) * | 1977-02-22 | 1981-09-22 | Roussel Uclaf | Cerebral vasodilating 20,21-dinoreburnamenine derivatives |
Also Published As
Publication number | Publication date |
---|---|
JPS49133400A (enrdf_load_stackoverflow) | 1974-12-21 |
PL94163B1 (enrdf_load_stackoverflow) | 1977-07-30 |
FR2209757A1 (enrdf_load_stackoverflow) | 1974-07-05 |
SE7702331L (sv) | 1977-03-02 |
SE415884B (sv) | 1980-11-10 |
SU589923A3 (ru) | 1978-01-25 |
SU629883A3 (ru) | 1978-10-25 |
CH593973A5 (enrdf_load_stackoverflow) | 1977-12-30 |
SE408646B (sv) | 1979-06-25 |
BE808245A (fr) | 1974-03-29 |
JPS5147720B2 (enrdf_load_stackoverflow) | 1976-12-16 |
CH591482A5 (enrdf_load_stackoverflow) | 1977-09-30 |
AT341686B (de) | 1978-02-27 |
DD108091A5 (enrdf_load_stackoverflow) | 1974-09-05 |
HU166766B (enrdf_load_stackoverflow) | 1975-05-28 |
ATA974773A (de) | 1977-06-15 |
FR2209757B1 (enrdf_load_stackoverflow) | 1977-09-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed [section 19, patents act 1949] | ||
PCNP | Patent ceased through non-payment of renewal fee |