GB1427612A - Process for producing l-tryptophan - Google Patents

Process for producing l-tryptophan

Info

Publication number
GB1427612A
GB1427612A GB2502573A GB2502573A GB1427612A GB 1427612 A GB1427612 A GB 1427612A GB 2502573 A GB2502573 A GB 2502573A GB 2502573 A GB2502573 A GB 2502573A GB 1427612 A GB1427612 A GB 1427612A
Authority
GB
United Kingdom
Prior art keywords
alanine
tryptophan
phenylalanine
hydroxamate
tyrosine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2502573A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KH Neochem Co Ltd
Original Assignee
Kyowa Hakko Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP5217672A external-priority patent/JPS4913382A/ja
Priority claimed from JP47114236A external-priority patent/JPS5119037B2/ja
Application filed by Kyowa Hakko Kogyo Co Ltd filed Critical Kyowa Hakko Kogyo Co Ltd
Publication of GB1427612A publication Critical patent/GB1427612A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/22—Tryptophan; Tyrosine; Phenylalanine; 3,4-Dihydroxyphenylalanine
    • C12P13/227—Tryptophan

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

1427612 L-Tryptophan KYOWA HAKKO KOGYO CO Ltd 24 May 1973 [27 May 1972 16 Nov 1972] 25025/73 Heading C2C L-Tryptophan is made by aerobically culturing a mutant strain of Corynebacterium glutamicum which (a) has a requirement for phenylalanine and tyrosine and is resistant to (b) at least one tryptophan analogue selected from 4-, 5- or 6-methyltryptophan 7-azatryptophan, 5- or 6-fluorotryptophan, tryptophan hydroxamate, α - methyltryptophan and 3 - indolylacrylic acid, and (c) at least one analogue of phenylalanine and/or tyrosine selected from (2-, 3- or 4-fluorophenyl)alanine, (2-, 3- or 4- methylphenyl)alanine, (2-, or 3-hydroxyphenyl)- alanine, (2-, 3- or 4-aminophenyl)alanine, (2- or 4 - nitrophenyl)alanine, # - (2-, or 3 - thienyl)- alanine, (2 - indolyl)alanine, (1 - naphthyl)- alanine, (2 - naphthyl)alanine, (2 - pyridyl)- alanine, (2-, or 3 - thiazolyl)alanine, phenylalanine hydroxamate, 3 - aminotyrosine, 3- fluorotyrosine, 3-hydroxytyrosine, 3-nitrotyrosine, (5-hydroxy-2-pyridyl)alanine and tyrosine hydroxamate. Fermentation is effected in an aqueous medium containing sources of carbon and nitrogen, inorganic nutrients and growth factors.
GB2502573A 1972-05-27 1973-05-24 Process for producing l-tryptophan Expired GB1427612A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP5217672A JPS4913382A (en) 1972-05-27 1972-05-27
JP47114236A JPS5119037B2 (en) 1972-11-16 1972-11-16

Publications (1)

Publication Number Publication Date
GB1427612A true GB1427612A (en) 1976-03-10

Family

ID=26392794

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2502573A Expired GB1427612A (en) 1972-05-27 1973-05-24 Process for producing l-tryptophan

Country Status (9)

Country Link
CA (1) CA997292A (en)
DK (1) DK133055C (en)
ES (1) ES415211A1 (en)
FR (1) FR2189510B1 (en)
GB (1) GB1427612A (en)
IT (1) IT991605B (en)
NL (1) NL7307353A (en)
NO (1) NO137210C (en)
SE (1) SE393398B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112251477A (en) * 2020-11-19 2021-01-22 乐康珍泰（天津）生物技术有限公司 Method for improving fermentation yield and sugar-acid conversion rate of L-phenylalanine

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0128637B1 (en) * 1983-04-13 1987-07-22 Ajinomoto Co., Inc. Process for the production of l-tryptophan by a fermentation process
JPS60176593A (en) * 1984-02-22 1985-09-10 Kyowa Hakko Kogyo Co Ltd Preparation of l-tryptophan

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112251477A (en) * 2020-11-19 2021-01-22 乐康珍泰（天津）生物技术有限公司 Method for improving fermentation yield and sugar-acid conversion rate of L-phenylalanine

Also Published As

Publication number Publication date
IT991605B (en) 1975-08-30
DK133055B (en) 1976-03-15
SE393398B (en) 1977-05-09
ES415211A1 (en) 1976-06-01
FR2189510B1 (en) 1976-04-23
DK133055C (en) 1976-08-23
FR2189510A1 (en) 1974-01-25
NO137210B (en) 1977-10-10
NL7307353A (en) 1973-11-29
NO137210C (en) 1978-01-18
CA997292A (en) 1976-09-21

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee