GB1417138A - Process for making amino indazole compounds - Google Patents

Process for making amino indazole compounds

Info

Publication number
GB1417138A
GB1417138A GB5523172A GB5523172A GB1417138A GB 1417138 A GB1417138 A GB 1417138A GB 5523172 A GB5523172 A GB 5523172A GB 5523172 A GB5523172 A GB 5523172A GB 1417138 A GB1417138 A GB 1417138A
Authority
GB
United Kingdom
Prior art keywords
alkyl group
alkylation
compound
nov
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB5523172A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Delmar Chemicals Inc
Original Assignee
Delmar Chemicals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Delmar Chemicals Inc filed Critical Delmar Chemicals Inc
Publication of GB1417138A publication Critical patent/GB1417138A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
    • C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

1417138 1 - Substituted - 3 - disubstitutedamino - alkoxy - 1H indazole derivatives DELMAR CHEMICALS Ltd 30 Nov 1972 [30 Nov 1971] 55231/72 Heading C2C A process for making 1-substituted-3-disubstituted aminoalkoxy-1H indazoles having the general formula or a salt thereof, wherein R is a hydrogen or halogen atom; R 1 is an alkyl group or an optionally substituted aryl or aralkyl group; R 2 is a hydrogen atom or an alkyl group; R 3 and R 4 are alkyl groups and n is 1 or 2, comprises the N-alkylation of a compound of the formula wherein R 5 is a hydrogen atom or an alkyl group, in the form of a free base or an acid addition or quaternary ammonium salt thereof. The N- alkylation is suitably effected by a reductive or direct alkylation procedure. The starting material may be obtained by condensing a primary or secondary amine with a carbonyl compound, e.g. an aldehyde, and subsequently reducing the resulting compound, e.g. by catalytic hydrogenation or by using a metal hydride, formic acid or a derivative thereof.
GB5523172A 1971-11-30 1971-11-30 Process for making amino indazole compounds Expired GB1417138A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US20344871A 1971-11-30 1971-11-30

Publications (1)

Publication Number Publication Date
GB1417138A true GB1417138A (en) 1975-12-10

Family

ID=22754059

Family Applications (1)

Application Number Title Priority Date Filing Date
GB5523172A Expired GB1417138A (en) 1971-11-30 1971-11-30 Process for making amino indazole compounds

Country Status (8)

Country Link
JP (1) JPS5123505B2 (en)
AU (1) AU4944572A (en)
CA (1) CA977760A (en)
DE (1) DE2258693A1 (en)
FR (1) FR2162109B1 (en)
GB (1) GB1417138A (en)
NL (1) NL7216289A (en)
ZA (1) ZA728510B (en)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1382855A (en) * 1963-08-09 1964-12-18 Acraf 3-dialkoylaminoalkoxy-indazoles substituted in position 1 and process for preparing them

Also Published As

Publication number Publication date
JPS4862756A (en) 1973-09-01
ZA728510B (en) 1973-08-29
FR2162109A1 (en) 1973-07-13
AU4944572A (en) 1974-05-30
JPS5123505B2 (en) 1976-07-17
NL7216289A (en) 1973-06-04
DE2258693A1 (en) 1973-06-07
FR2162109B1 (en) 1976-04-23
CA977760A (en) 1975-11-11

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Legal Events

Date Code Title Description
PS Patent sealed
PLNP Patent lapsed through nonpayment of renewal fees