GB1410852A - Substituted 4-biphenylyl-butenoic acids esters and amides and pharmaceutical compositions containing them - Google Patents
Substituted 4-biphenylyl-butenoic acids esters and amides and pharmaceutical compositions containing themInfo
- Publication number
- GB1410852A GB1410852A GB3884473A GB3884473A GB1410852A GB 1410852 A GB1410852 A GB 1410852A GB 3884473 A GB3884473 A GB 3884473A GB 3884473 A GB3884473 A GB 3884473A GB 1410852 A GB1410852 A GB 1410852A
- Authority
- GB
- United Kingdom
- Prior art keywords
- formula
- alkoxy
- compounds
- biphenylyl
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- RWDLDKBHYBMTDJ-UHFFFAOYSA-N 4-(2-phenylphenyl)but-2-enoic acid Chemical class OC(=O)C=CCC1=CC=CC=C1C1=CC=CC=C1 RWDLDKBHYBMTDJ-UHFFFAOYSA-N 0.000 title abstract 2
- 150000001408 amides Chemical class 0.000 title 1
- 239000008194 pharmaceutical composition Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 8
- 125000003545 alkoxy group Chemical group 0.000 abstract 5
- 125000005843 halogen group Chemical group 0.000 abstract 2
- -1 B is OH Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 230000001741 anti-phlogistic effect Effects 0.000 abstract 1
- 239000012024 dehydrating agents Substances 0.000 abstract 1
- 150000007529 inorganic bases Chemical class 0.000 abstract 1
- 125000000896 monocarboxylic acid group Chemical group 0.000 abstract 1
- 150000007530 organic bases Chemical class 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C245/00—Compounds containing chains of at least two nitrogen atoms with at least one nitrogen-to-nitrogen multiple bond
- C07C245/12—Diazo compounds, i.e. compounds having the free valencies of >N2 groups attached to the same carbon atom
- C07C245/14—Diazo compounds, i.e. compounds having the free valencies of >N2 groups attached to the same carbon atom having diazo groups bound to acyclic carbon atoms of a carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C17/00—Preparation of halogenated hydrocarbons
- C07C17/093—Preparation of halogenated hydrocarbons by replacement by halogens
- C07C17/16—Preparation of halogenated hydrocarbons by replacement by halogens of hydroxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C17/00—Preparation of halogenated hydrocarbons
- C07C17/093—Preparation of halogenated hydrocarbons by replacement by halogens
- C07C17/20—Preparation of halogenated hydrocarbons by replacement by halogens of halogen atoms by other halogen atoms
- C07C17/202—Preparation of halogenated hydrocarbons by replacement by halogens of halogen atoms by other halogen atoms two or more compounds being involved in the reaction
- C07C17/208—Preparation of halogenated hydrocarbons by replacement by halogens of halogen atoms by other halogen atoms two or more compounds being involved in the reaction the other compound being MX
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
- C07C45/46—Friedel-Crafts reactions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/56—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
- C07C45/57—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom
- C07C45/58—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom in three-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/80—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen
- C07C49/813—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen polycyclic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
- C07C57/58—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
- C07C57/58—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
- C07C57/60—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings having unsaturation outside the rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/64—Acyl halides
- C07C57/76—Acyl halides containing halogen outside the carbonyl halide groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
- C07C59/56—Unsaturated compounds containing hydroxy or O-metal groups containing halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/48—Compounds containing oxirane rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/32—Oxygen atoms
- C07D307/33—Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/54—Quaternary phosphonium compounds
- C07F9/5407—Acyclic saturated phosphonium compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
- C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2240441A DE2240441A1 (de) | 1972-08-17 | 1972-08-17 | Neue biphenylderivate und verfahren zur herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1410852A true GB1410852A (en) | 1975-10-22 |
Family
ID=5853790
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB3884473A Expired GB1410852A (en) | 1972-08-17 | 1973-08-16 | Substituted 4-biphenylyl-butenoic acids esters and amides and pharmaceutical compositions containing them |
| GB3884373A Expired GB1411495A (en) | 1972-08-17 | 1973-08-16 | Substituted-4-biphenyl-3-hydroxybutyric acids esters and amides and pharmaceutical compositions containing them |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB3884373A Expired GB1411495A (en) | 1972-08-17 | 1973-08-16 | Substituted-4-biphenyl-3-hydroxybutyric acids esters and amides and pharmaceutical compositions containing them |
Country Status (19)
| Country | Link |
|---|---|
| JP (2) | JPS49124051A (cg-RX-API-DMAC10.html) |
| AT (3) | AT323144B (cg-RX-API-DMAC10.html) |
| AU (2) | AU476340B2 (cg-RX-API-DMAC10.html) |
| BE (3) | BE803734A (cg-RX-API-DMAC10.html) |
| BG (3) | BG21197A3 (cg-RX-API-DMAC10.html) |
| CH (1) | CH588435A5 (cg-RX-API-DMAC10.html) |
| CS (3) | CS165386B2 (cg-RX-API-DMAC10.html) |
| DD (2) | DD107901A5 (cg-RX-API-DMAC10.html) |
| DE (1) | DE2240441A1 (cg-RX-API-DMAC10.html) |
| ES (4) | ES417884A1 (cg-RX-API-DMAC10.html) |
| FR (2) | FR2196167B1 (cg-RX-API-DMAC10.html) |
| GB (2) | GB1410852A (cg-RX-API-DMAC10.html) |
| HU (2) | HU166516B (cg-RX-API-DMAC10.html) |
| IL (2) | IL43003A0 (cg-RX-API-DMAC10.html) |
| NL (2) | NL7311300A (cg-RX-API-DMAC10.html) |
| PL (2) | PL94510B1 (cg-RX-API-DMAC10.html) |
| RO (2) | RO62918A (cg-RX-API-DMAC10.html) |
| SU (11) | SU482039A3 (cg-RX-API-DMAC10.html) |
| ZA (3) | ZA735616B (cg-RX-API-DMAC10.html) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2457275A1 (fr) * | 1979-05-21 | 1980-12-19 | Fabre Sa Pierre | Acides p-biphenyl-4 methyl-2 buten-3 oiques utiles dans le traitement des rhumatismes |
| RU2686489C1 (ru) * | 2018-12-27 | 2019-04-29 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Санкт-Петербургский государственный университет (СПбГУ)" | Способ получения α-диазокарбонильных соединений в водной среде |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2162038A1 (de) * | 1970-05-05 | 1972-08-17 | William H Rorer Ine , Fort Washington, Pa (V St A ) | Verfahren zur Herstellung von synthe tischen Alkansauren und deren Derivaten |
| BE776316R (fr) * | 1971-03-10 | 1972-06-06 | Rorer Inc William H | Nouveaux derives d'acides phenyl-acetiques substitues et procede pour leur |
-
1972
- 1972-08-17 DE DE2240441A patent/DE2240441A1/de active Pending
-
1973
- 1973-08-14 ES ES417884A patent/ES417884A1/es not_active Expired
- 1973-08-14 AT AT710873A patent/AT323144B/de not_active IP Right Cessation
- 1973-08-14 AT AT711273A patent/AT328427B/de not_active IP Right Cessation
- 1973-08-14 AT AT710773A patent/AT323143B/de not_active IP Right Cessation
- 1973-08-14 CH CH1170773A patent/CH588435A5/xx not_active IP Right Cessation
- 1973-08-14 ES ES417883A patent/ES417883A1/es not_active Expired
- 1973-08-15 DD DD172907A patent/DD107901A5/xx unknown
- 1973-08-15 HU HUTO925A patent/HU166516B/hu unknown
- 1973-08-15 SU SU1958291A patent/SU482039A3/ru active
- 1973-08-15 HU HUTO926A patent/HU166517B/hu unknown
- 1973-08-15 SU SU1958288A patent/SU484679A3/ru active
- 1973-08-15 DD DD172906A patent/DD108071A5/xx unknown
- 1973-08-15 BG BG024327A patent/BG21197A3/xx unknown
- 1973-08-15 BG BG24328A patent/BG22069A3/xx unknown
- 1973-08-15 SU SU1958290A patent/SU511846A3/ru active
- 1973-08-15 BG BG027671A patent/BG21844A3/xx unknown
- 1973-08-16 IL IL43003A patent/IL43003A0/xx unknown
- 1973-08-16 NL NL7311300A patent/NL7311300A/xx unknown
- 1973-08-16 PL PL1973186474A patent/PL94510B1/pl unknown
- 1973-08-16 ZA ZA00735616A patent/ZA735616B/xx unknown
- 1973-08-16 ZA ZA00735628A patent/ZA735628B/xx unknown
- 1973-08-16 GB GB3884473A patent/GB1410852A/en not_active Expired
- 1973-08-16 NL NL7311301A patent/NL7311301A/xx unknown
- 1973-08-16 ZA ZA00735629A patent/ZA735629B/xx unknown
- 1973-08-16 IL IL43004A patent/IL43004A0/xx unknown
- 1973-08-16 JP JP48092052A patent/JPS49124051A/ja active Pending
- 1973-08-16 PL PL1973164708A patent/PL90397B1/pl unknown
- 1973-08-16 CS CS4903A patent/CS165386B2/cs unknown
- 1973-08-16 CS CS4904A patent/CS165387B2/cs unknown
- 1973-08-16 CS CS5793A patent/CS165385B2/cs unknown
- 1973-08-16 JP JP48092053A patent/JPS49124052A/ja active Pending
- 1973-08-16 GB GB3884373A patent/GB1411495A/en not_active Expired
- 1973-08-16 AU AU59309/73A patent/AU476340B2/en not_active Expired
- 1973-08-16 AU AU59308/73A patent/AU5930873A/en not_active Expired
- 1973-08-17 RO RO7300075822A patent/RO62918A/ro unknown
- 1973-08-17 FR FR7330075A patent/FR2196167B1/fr not_active Expired
- 1973-08-17 FR FR7330076A patent/FR2196168B1/fr not_active Expired
- 1973-08-17 BE BE134691A patent/BE803734A/xx unknown
- 1973-08-17 RO RO7300075821A patent/RO62917A/ro unknown
- 1973-08-17 BE BE134689A patent/BE803732A/xx unknown
- 1973-08-17 BE BE134690A patent/BE803733A/xx unknown
-
1974
- 1974-10-21 SU SU2069110A patent/SU554810A3/ru active
- 1974-10-21 SU SU2069774A patent/SU552021A3/ru active
- 1974-10-21 SU SU2069771A patent/SU520030A3/ru active
- 1974-10-21 SU SU2069576A patent/SU561505A3/ru active
- 1974-10-21 SU SU2069114A patent/SU538658A3/ru active
- 1974-10-21 SU SU2069577A patent/SU520907A3/ru active
- 1974-10-21 SU SU2069578A patent/SU511847A3/ru active
- 1974-10-21 SU SU7402069575A patent/SU577967A3/ru active
- 1974-11-30 ES ES432464A patent/ES432464A1/es not_active Expired
- 1974-11-30 ES ES432465A patent/ES432465A1/es not_active Expired
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES8104233A1 (es) | Procedimiento para preparar derivados de acidos quinolina- carboxilicos | |
| GB1468012A (en) | 2-amino-3-carboxy-thiophene derivatives | |
| IE40511B1 (en) | N-(1-(-phenylalkyl)-piperidyl-j)-(-(-pyridyl)-carbonic acid amides | |
| GB1505885A (en) | Substituted cephalosporins | |
| GB991586A (en) | Process for the preparation of penicillins | |
| GB1169945A (en) | Pharmaceutical Compositions containing Diphenylalkyl-amine Derivatives | |
| DE2965701D1 (en) | 1-imidazol-2-ylidene-3-thienyl-urea derivatives, processes therefor, and pharmaceutical compositions | |
| GB1497039A (en) | Penicillins and cephalosporins | |
| GB1241637A (en) | Improvements in or relating to anti-inflammatory compositions | |
| GB1164555A (en) | New Tropine Derivatives | |
| GB1411495A (en) | Substituted-4-biphenyl-3-hydroxybutyric acids esters and amides and pharmaceutical compositions containing them | |
| GB1438419A (en) | 2-oxo-1-pyridinyl penicillin and cephalosporin derivatives | |
| GB1412546A (en) | Morpholine derivatives | |
| GB1316361A (en) | 5h-dibenzazepines | |
| GB1377316A (en) | Dialkylaminoalkyl esters of arylaliphatic acids and acid addition salts thereof | |
| GB1361249A (en) | 3-sulphoalkyl-6-hydroxy-pyrid--2--ones their manufacture and use | |
| ES399014A1 (es) | Procedimiento para la preparacion de derivados de acido 6-amino-penicilanico. | |
| GB894460A (en) | Improvements in or relating to penicillins | |
| GB1501476A (en) | Process for the preparation of reactive penicillanic acid and cephalosporanic acid derivatives and a process for the preparation thereof | |
| ES352579A1 (es) | Un procedimiento para la preparacion de un oxazol sustitui-do por monoarilo. | |
| GB1242096A (en) | Benzobenzofuranooxepine compounds and process for preparing the same | |
| GB1327536A (en) | Xanthen-2-yl-propionic acids | |
| GB1298507A (en) | N-substituted 3-carbamoyl-1-thia-isochroman-1,1-dioxide derivatives | |
| ES414340A1 (es) | Procedimiento de preparacion de derivados de la n-(m-tri- fluormetiltio-fenil-)-piperazina. | |
| GB1234625A (cg-RX-API-DMAC10.html) |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PLNP | Patent lapsed through nonpayment of renewal fees |