GB1409733A - Triiodinated n-methyl-dicarboxylic acid anilides and process for their manufacture - Google Patents

Triiodinated n-methyl-dicarboxylic acid anilides and process for their manufacture

Info

Publication number
GB1409733A
GB1409733A GB3673472A GB3673472A GB1409733A GB 1409733 A GB1409733 A GB 1409733A GB 3673472 A GB3673472 A GB 3673472A GB 3673472 A GB3673472 A GB 3673472A GB 1409733 A GB1409733 A GB 1409733A
Authority
GB
United Kingdom
Prior art keywords
alkoxy
hydroxyl
group
halogen
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB3673472A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering AG filed Critical Schering AG
Publication of GB1409733A publication Critical patent/GB1409733A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
    • C07D207/27—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
GB3673472A 1971-08-17 1972-08-07 Triiodinated n-methyl-dicarboxylic acid anilides and process for their manufacture Expired GB1409733A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2141803A DE2141803A1 (de) 1971-08-17 1971-08-17 Trijodierte n-methyl-dicarbonsaeureani-lide und verfahren zu iher herstellung

Publications (1)

Publication Number Publication Date
GB1409733A true GB1409733A (en) 1975-10-15

Family

ID=5817319

Family Applications (1)

Application Number Title Priority Date Filing Date
GB3673472A Expired GB1409733A (en) 1971-08-17 1972-08-07 Triiodinated n-methyl-dicarboxylic acid anilides and process for their manufacture

Country Status (18)

Country Link
US (1) US4001298A (enExample)
JP (1) JPS4829736A (enExample)
AR (1) AR204073A1 (enExample)
AT (2) AT317417B (enExample)
AU (1) AU476763B2 (enExample)
BE (1) BE787669A (enExample)
CA (1) CA977759A (enExample)
DD (1) DD100156A5 (enExample)
DE (1) DE2141803A1 (enExample)
DK (1) DK132375C (enExample)
ES (2) ES405769A1 (enExample)
FR (1) FR2150784B1 (enExample)
GB (1) GB1409733A (enExample)
HU (1) HU164151B (enExample)
IL (1) IL40088A (enExample)
NL (1) NL7209286A (enExample)
SU (1) SU474974A3 (enExample)
ZA (1) ZA725664B (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4225725A (en) * 1975-10-20 1980-09-30 Mallinckrodt, Inc. Lower alkoxymethyl esters of 2,4,6-triiodobenzoic acid derivatives
GB1539791A (en) * 1976-04-08 1979-02-07 Guerbet Sa X-ray contrast media
DE2628517C2 (de) * 1976-06-23 1985-02-21 Schering AG, 1000 Berlin und 4709 Bergkamen Dicarbonsäure-bis(3,5-dicarbamoyl-2,4,6-trijodanilid)-Verbindungen, Verfahren zu ihrer Herstellung und Röntgenkontrastmittel
DE2629228C2 (de) * 1976-06-25 1984-10-18 Schering AG, 1000 Berlin und 4709 Bergkamen Jodierte Isophthalamsäure-Derivate Verfahren zu deren Herstellung sowie deren Verwendung
EP0079397A1 (de) * 1981-11-13 1983-05-25 Schering Aktiengesellschaft Unsymmetrisch substituierte Dicarbonsäure-bis-(2,4,-6-trijodanilide), deren Herstellung und diese enthaltende Röntgenkontrastmittel
CA1327600C (en) * 1987-05-22 1994-03-08 Ernest Felder Process for the preparation of 5-acylamino-2,4,6- triiodo-or tribromo-benzoic acid derivatives and corresponding novel 5-acylamino-2,4,6-triiodo or tribromo-benzoic acid derivatives obtained by said process
US5614638A (en) * 1989-11-29 1997-03-25 Bracco International B.V. Nonionic radiographic contrast agents
US5869024A (en) * 1989-11-29 1999-02-09 Bracco International B.V. Methods and compositions for using non-ionic contrast agents to reduce the risk of clot formation in diagnostic procedures
US5527926A (en) * 1990-11-26 1996-06-18 Bracco International B.V. Methods and compositions for using non-ionic contrast agents to reduce the risk of clot formation in diagnostic procedures
US5278311A (en) * 1992-06-05 1994-01-11 E. R. Squibb & Sons, Inc. Nonionic radiographic contrast agents
US5463080A (en) * 1992-08-27 1995-10-31 Bracco International B.V. 2,4,6-triiodo-1,3-benzenedicarboxylic acid compounds used as radiolabelling reagents

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3542861A (en) * 1967-05-08 1970-11-24 Sterling Drug Inc 3-amino-5-cycloalkylcarbonylamino-2,4,6-triiodobenzoic acids
US3732293A (en) * 1968-03-15 1973-05-08 Sterling Drug Inc Iodinated bis(aminobenzoic acids) and esters thereof

Also Published As

Publication number Publication date
DD100156A5 (enExample) 1973-09-12
ES405770A1 (es) 1975-09-16
AU4565072A (en) 1974-02-21
DK132375B (da) 1975-12-01
AR204073A1 (es) 1975-11-20
AT329543B (de) 1976-05-10
DE2141803A1 (de) 1973-03-01
IL40088A0 (en) 1972-10-29
DK132375C (da) 1976-05-03
IL40088A (en) 1976-05-31
ATA713473A (de) 1975-08-15
FR2150784A1 (enExample) 1973-04-13
FR2150784B1 (enExample) 1975-06-20
AU476763B2 (en) 1976-10-07
NL7209286A (enExample) 1973-02-20
BE787669A (fr) 1973-02-19
ES405769A1 (es) 1975-09-16
HU164151B (enExample) 1973-12-28
JPS4829736A (enExample) 1973-04-19
ZA725664B (en) 1973-05-30
US4001298A (en) 1977-01-04
CA977759A (en) 1975-11-11
AT317417B (de) 1974-08-26
SU474974A3 (ru) 1975-06-25

Similar Documents

Publication Publication Date Title
PH22336A (en) A reactive derivative of 2,3-dioxapiperazine derivative
GB1409733A (en) Triiodinated n-methyl-dicarboxylic acid anilides and process for their manufacture
GB1488903A (en) X-ray contrast media
ES394370A1 (es) Procedimiento para la preparacion de derivados de la inso-indolina.
GB1241617A (en) New carboxylic acid amides, processes for their manufacture and their use
GB1369999A (en) Monomethyl-amino-triidobenzene compounds for use as x-ray shading agents
SE7710916L (sv) Anvendning av ortofosforsyraestrar i vattenhaltiga metallbearbetningsvetskor
ES423233A1 (es) Procedimiento para la preparacion de nuevas 2-fenilamino- imidazolinas-(2) sustituidas.
ES421068A1 (es) Procedimiento para la preparacion de nuevas 2-fenilamino- imidazolinas sustituidas.
ES385634A1 (es) Procedimiento para la preparacion de n - cicloalcohil - a- ril - amino - imidazolinas-(2) sustituidas.
ES399003A1 (es) Procedimiento para la preparacion de 2-arilamino-imidazoli-nas-(2) sustituidas.
ES441775A1 (es) Procedimiento para preparar colorantes antraquinonicos solu-bles en agua.
GB1227295A (enExample)
ES382564A1 (es) Procedimiento para la preparacion de derivados de la dihi- dro-10,11 dibenzo (b,f) azepina.
GB1499608A (en) Polybenzoxazoles
ES444180A1 (es) Un procedimiento para la preparacion de 6-amino-2, 2-dimetil-3-(5-tetrazolil) penam.
ES308051A1 (es) Procedimiento para la elaboracion de nuevos esteres de acido carboxilico, basicamente sustituidos.
ES439141A1 (es) Procedimiento para la produccion de hidroxialquilxantinas.
ES389369A1 (es) Procedimiento para la produccion de piperidil - furanonas sustituidas.
ES377921A1 (es) Procedimiento para la preparacion de derivados del acido adamantilcarboxamidofenilacetico.
GB1209631A (en) Pyrazoline compounds
ES302772A1 (es) Procedimiento para la obtencion de nuevos compuestos carbociclicos.
ES300123A1 (es) Un procedimiento para la preparación de nuevos derivados de piperazina sustituídos asimétricamente
ES441880A1 (es) Un procedimiento de preparacion de derivados de acidos 2- hidroximetil-tiazol-5-carboxilicos.
GB961627A (en) Penicillins

Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PLNP Patent lapsed through nonpayment of renewal fees