GB1409185A - Tetrahydro pyrrolo 1,2-a pyrazine-1 2h, 4 3h-diones - Google Patents

Tetrahydro pyrrolo 1,2-a pyrazine-1 2h, 4 3h-diones

Info

Publication number
GB1409185A
GB1409185A GB4580773A GB4580773A GB1409185A GB 1409185 A GB1409185 A GB 1409185A GB 4580773 A GB4580773 A GB 4580773A GB 4580773 A GB4580773 A GB 4580773A GB 1409185 A GB1409185 A GB 1409185A
Authority
GB
United Kingdom
Prior art keywords
compounds
alkoxy
prepared
compound
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB4580773A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gruppo Lepetit SpA
Original Assignee
Gruppo Lepetit SpA
Lepetit SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruppo Lepetit SpA, Lepetit SpA filed Critical Gruppo Lepetit SpA
Publication of GB1409185A publication Critical patent/GB1409185A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GB4580773A 1972-11-03 1973-10-01 Tetrahydro pyrrolo 1,2-a pyrazine-1 2h, 4 3h-diones Expired GB1409185A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT3127672 1972-11-03

Publications (1)

Publication Number Publication Date
GB1409185A true GB1409185A (en) 1975-10-08

Family

ID=11233382

Family Applications (1)

Application Number Title Priority Date Filing Date
GB4580773A Expired GB1409185A (en) 1972-11-03 1973-10-01 Tetrahydro pyrrolo 1,2-a pyrazine-1 2h, 4 3h-diones

Country Status (18)

Country Link
US (1) US3920660A (enExample)
JP (1) JPS4976896A (enExample)
AR (1) AR206504A1 (enExample)
AT (1) AT336622B (enExample)
AU (1) AU475776B2 (enExample)
BE (1) BE806827A (enExample)
DD (1) DD107930A5 (enExample)
DE (1) DE2354056A1 (enExample)
ES (2) ES420175A1 (enExample)
FR (1) FR2205323B1 (enExample)
GB (1) GB1409185A (enExample)
HU (1) HU166438B (enExample)
IL (2) IL43485A0 (enExample)
LU (1) LU68719A1 (enExample)
NL (1) NL7314665A (enExample)
RO (1) RO63259A (enExample)
SU (1) SU513627A3 (enExample)
ZA (1) ZA737653B (enExample)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0362555A1 (de) * 1988-09-03 1990-04-11 Hoechst Aktiengesellschaft Piperazindione mit psychotroper Wirkung
US9856273B2 (en) 2012-10-22 2018-01-02 City Of Hope ETP derivatives
US11584760B2 (en) 2016-09-15 2023-02-21 City Of Hope Dithio ETP derivatives

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4595766A (en) * 1984-10-26 1986-06-17 Ciba-Geigy Corporation Process for the preparation of an indoline carboxylic acid
US4697016A (en) * 1984-10-26 1987-09-29 Ciba-Geigy Corporation Intermediates for the preparation of a carboxylic acid
JPH0745501B2 (ja) * 1986-11-27 1995-05-17 日本臓器製薬株式会社 新規環状ジペプチド化合物
AU4376893A (en) * 1992-05-19 1993-12-13 Immunopharmaceutics, Inc. Compounds that modulate endothelin activity
US6057314A (en) * 1995-12-21 2000-05-02 Biochem Pharma Inc. Low molecular weight bicyclic thrombin inhibitors
US5958905A (en) 1996-03-26 1999-09-28 Texas Biotechnology Corporation Phosphoramidates, phosphinic amides and related compounds and the use thereof to modulate the activity of endothelin
US6124291A (en) * 1996-06-18 2000-09-26 Warner-Lambert Company Pyrrolo[1,2-a]pyrazine-1,4-dione serine protease inhibitors
MXPA02006134A (es) 1999-12-21 2002-12-13 Guilford Pharm Inc Compuestos derivados de hidantoina, composiciones farmaceuticas y metodos de uso de los mismos.
US6815214B2 (en) 2000-12-29 2004-11-09 Celltech R & D, Inc. Pharmaceutical uses and synthesis of diketopiperazines

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3176017A (en) * 1963-02-26 1965-03-30 American Home Prod Aroylalkyl derivatives of diazabicyclo-nonanes and-decanes
US3503980A (en) * 1965-10-04 1970-03-31 Ciba Geigy Corp Tetrahydroazacycloalkano(1,2-a) pyridazines
DE1695554C3 (de) * 1966-02-12 1974-02-21 Nautschno-Issledowatelskij Institut Farmakologii I Chimioterapii, Moskau Verfahren zur Herstellung kondensierter Piperazinonderivate
US3563992A (en) * 1967-10-31 1971-02-16 Abbott Lab 1,4-diaza-bicyclo(4,3,0)nonane-2,5,9-triones

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0362555A1 (de) * 1988-09-03 1990-04-11 Hoechst Aktiengesellschaft Piperazindione mit psychotroper Wirkung
AU627491B2 (en) * 1988-09-03 1992-08-27 Hoechst Aktiengesellschaft Piperazinediones having a psychotropic action
US9856273B2 (en) 2012-10-22 2018-01-02 City Of Hope ETP derivatives
CN108440571A (zh) * 2012-10-22 2018-08-24 希望之城 Etp衍生物
US10246471B2 (en) 2012-10-22 2019-04-02 City Of Hope ETP derivatives
EP2909214B1 (en) * 2012-10-22 2020-07-22 City of Hope Etp derivatives
US11584760B2 (en) 2016-09-15 2023-02-21 City Of Hope Dithio ETP derivatives

Also Published As

Publication number Publication date
RO63259A (fr) 1978-08-15
DE2354056A1 (de) 1974-05-16
ES420175A1 (es) 1976-07-16
NL7314665A (enExample) 1974-05-07
US3920660A (en) 1975-11-18
BE806827A (fr) 1974-02-15
LU68719A1 (enExample) 1974-01-08
SU513627A3 (ru) 1976-05-05
ES421819A1 (es) 1976-06-16
JPS4976896A (enExample) 1974-07-24
IL43485A0 (en) 1974-01-14
FR2205323A1 (enExample) 1974-05-31
AU475776B2 (en) 1976-09-02
HU166438B (enExample) 1975-03-28
AR206504A1 (es) 1976-07-30
ATA925273A (de) 1976-09-15
ZA737653B (en) 1974-08-28
AU6141773A (en) 1975-04-17
IL43606A0 (en) 1974-03-14
DD107930A5 (enExample) 1974-08-20
FR2205323B1 (enExample) 1976-12-03
AT336622B (de) 1977-05-10

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PLNP Patent lapsed through nonpayment of renewal fees