GB1397663A - Phenoxypropylamine derivatives and the preparation thereof - Google Patents
Phenoxypropylamine derivatives and the preparation thereofInfo
- Publication number
- GB1397663A GB1397663A GB568173A GB568173A GB1397663A GB 1397663 A GB1397663 A GB 1397663A GB 568173 A GB568173 A GB 568173A GB 568173 A GB568173 A GB 568173A GB 1397663 A GB1397663 A GB 1397663A
- Authority
- GB
- United Kingdom
- Prior art keywords
- alkyl
- urea
- compounds
- formula
- hydroxyalkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- DXVQSHRBALIFBC-UHFFFAOYSA-N 3-phenoxypropan-1-amine Chemical class NCCCOC1=CC=CC=C1 DXVQSHRBALIFBC-UHFFFAOYSA-N 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 10
- 150000001875 compounds Chemical class 0.000 abstract 5
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 abstract 2
- 125000002853 C1-C4 hydroxyalkyl group Chemical group 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- 125000001931 aliphatic group Chemical group 0.000 abstract 2
- 125000002947 alkylene group Chemical group 0.000 abstract 2
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 2
- 239000004202 carbamide Substances 0.000 abstract 2
- 229910052799 carbon Inorganic materials 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 150000003672 ureas Chemical class 0.000 abstract 2
- LBUGLKXPDFYPFZ-UHFFFAOYSA-N (3-hydroxyphenyl)methylurea Chemical compound NC(=O)NCC1=CC=CC(O)=C1 LBUGLKXPDFYPFZ-UHFFFAOYSA-N 0.000 abstract 1
- BHSVODXUUFNIPW-UHFFFAOYSA-N (4-hydroxy-3-methoxyphenyl)methylurea Chemical compound COC1=CC(CNC(N)=O)=CC=C1O BHSVODXUUFNIPW-UHFFFAOYSA-N 0.000 abstract 1
- VLRGXXKFHVJQOL-UHFFFAOYSA-N 3-chloropentane-2,4-dione Chemical compound CC(=O)C(Cl)C(C)=O VLRGXXKFHVJQOL-UHFFFAOYSA-N 0.000 abstract 1
- 125000006577 C1-C6 hydroxyalkyl group Chemical group 0.000 abstract 1
- 125000006374 C2-C10 alkenyl group Chemical group 0.000 abstract 1
- 125000000882 C2-C6 alkenyl group Chemical group 0.000 abstract 1
- 125000003320 C2-C6 alkenyloxy group Chemical group 0.000 abstract 1
- BRLQWZUYTZBJKN-UHFFFAOYSA-N Epichlorohydrin Chemical compound ClCC1CO1 BRLQWZUYTZBJKN-UHFFFAOYSA-N 0.000 abstract 1
- 239000004593 Epoxy Substances 0.000 abstract 1
- 125000004442 acylamino group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000304 alkynyl group Chemical group 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 125000006620 amino-(C1-C6) alkyl group Chemical group 0.000 abstract 1
- 125000004103 aminoalkyl group Chemical group 0.000 abstract 1
- 229910021529 ammonia Inorganic materials 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000003236 benzoyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C(*)=O 0.000 abstract 1
- 229910052794 bromium Inorganic materials 0.000 abstract 1
- 150000001728 carbonyl compounds Chemical class 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 229910052740 iodine Inorganic materials 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 125000000466 oxiranyl group Chemical group 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 125000002572 propoxy group Chemical group [*]OC([H])([H])C(C([H])([H])[H])([H])[H] 0.000 abstract 1
- 159000000000 sodium salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
- C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
- C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AT157372A AT321315B (de) | 1972-02-28 | 1972-02-28 | Verfahren zur Herstellung von neuen Ureidophenoxypropylaminderivaten und von deren Salzen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1397663A true GB1397663A (en) | 1975-06-18 |
Family
ID=3516334
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB568173A Expired GB1397663A (en) | 1972-02-28 | 1973-02-05 | Phenoxypropylamine derivatives and the preparation thereof |
Country Status (21)
| Country | Link |
|---|---|
| JP (1) | JPS5626654B2 (enExample) |
| AT (1) | AT321315B (enExample) |
| BE (1) | BE796029A (enExample) |
| CH (1) | CH577956A5 (enExample) |
| CS (1) | CS168625B2 (enExample) |
| DD (1) | DD105214A1 (enExample) |
| DE (1) | DE2264182C3 (enExample) |
| DK (1) | DK136185B (enExample) |
| ES (1) | ES412061A1 (enExample) |
| FI (1) | FI59582C (enExample) |
| FR (1) | FR2173990B1 (enExample) |
| GB (1) | GB1397663A (enExample) |
| HU (1) | HU165235B (enExample) |
| IE (1) | IE37271B1 (enExample) |
| LU (1) | LU66869A1 (enExample) |
| NL (1) | NL7300688A (enExample) |
| PL (1) | PL82613B1 (enExample) |
| RO (1) | RO62862A (enExample) |
| SU (1) | SU530639A3 (enExample) |
| YU (1) | YU36158B (enExample) |
| ZA (1) | ZA73949B (enExample) |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1149819A (en) * | 1970-01-08 | 1983-07-12 | Max Wilhelm | Process for the manufacture of new amines |
-
1972
- 1972-02-28 AT AT157372A patent/AT321315B/de not_active IP Right Cessation
- 1972-12-29 DE DE2264182A patent/DE2264182C3/de not_active Expired
- 1972-12-29 PL PL1972159973A patent/PL82613B1/pl unknown
-
1973
- 1973-01-10 FI FI60/73A patent/FI59582C/fi active
- 1973-01-17 RO RO7300073527A patent/RO62862A/ro unknown
- 1973-01-17 NL NL7300688A patent/NL7300688A/xx not_active Application Discontinuation
- 1973-01-17 CS CS388A patent/CS168625B2/cs unknown
- 1973-01-19 LU LU66869A patent/LU66869A1/xx unknown
- 1973-02-02 YU YU260/73A patent/YU36158B/xx unknown
- 1973-02-05 SU SU1879539A patent/SU530639A3/ru active
- 1973-02-05 GB GB568173A patent/GB1397663A/en not_active Expired
- 1973-02-05 FR FR7303913A patent/FR2173990B1/fr not_active Expired
- 1973-02-06 DK DK60373AA patent/DK136185B/da unknown
- 1973-02-08 IE IE198/73A patent/IE37271B1/xx unknown
- 1973-02-09 ZA ZA730949A patent/ZA73949B/xx unknown
- 1973-02-13 HU HUOE189A patent/HU165235B/hu unknown
- 1973-02-26 DD DD169049A patent/DD105214A1/xx unknown
- 1973-02-26 CH CH275373A patent/CH577956A5/xx not_active IP Right Cessation
- 1973-02-26 ES ES73412061A patent/ES412061A1/es not_active Expired
- 1973-02-26 JP JP2229773A patent/JPS5626654B2/ja not_active Expired
- 1973-02-27 BE BE128160A patent/BE796029A/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| NL7300688A (enExample) | 1973-08-30 |
| AU5205273A (en) | 1974-08-15 |
| FR2173990A1 (enExample) | 1973-10-12 |
| SU530639A3 (ru) | 1976-09-30 |
| AT321315B (de) | 1975-03-25 |
| JPS5626654B2 (enExample) | 1981-06-19 |
| FR2173990B1 (enExample) | 1976-09-03 |
| IE37271L (en) | 1973-08-28 |
| CS168625B2 (enExample) | 1976-06-29 |
| CH577956A5 (enExample) | 1976-07-30 |
| FI59582C (fi) | 1981-09-10 |
| DE2264182A1 (de) | 1973-12-20 |
| IE37271B1 (en) | 1977-06-08 |
| HU165235B (enExample) | 1974-07-27 |
| JPS4897838A (enExample) | 1973-12-13 |
| DK136185B (da) | 1977-08-29 |
| YU26073A (en) | 1981-06-30 |
| ES412061A1 (es) | 1976-01-01 |
| DE2264182C3 (de) | 1982-03-18 |
| YU36158B (en) | 1982-02-25 |
| PL82613B1 (enExample) | 1975-10-31 |
| DK136185C (enExample) | 1978-02-13 |
| LU66869A1 (enExample) | 1973-03-19 |
| FI59582B (fi) | 1981-05-29 |
| DD105214A1 (enExample) | 1974-04-12 |
| ZA73949B (en) | 1973-11-28 |
| BE796029A (fr) | 1973-08-27 |
| RO62862A (fr) | 1978-02-15 |
| DE2264182B2 (de) | 1981-06-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| 732 | Registration of transactions, instruments or events in the register (sect. 32/1977) | ||
| PCNP | Patent ceased through non-payment of renewal fee |