GB1391933A - Nitrofuryl-pyrimidine derivatives - Google Patents
Nitrofuryl-pyrimidine derivativesInfo
- Publication number
- GB1391933A GB1391933A GB1152872A GB1152872A GB1391933A GB 1391933 A GB1391933 A GB 1391933A GB 1152872 A GB1152872 A GB 1152872A GB 1152872 A GB1152872 A GB 1152872A GB 1391933 A GB1391933 A GB 1391933A
- Authority
- GB
- United Kingdom
- Prior art keywords
- group
- compound
- resulting
- hydrogen
- acyloxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
1391933 Nitrofurylpyrimidines SCHEBING AG 13 March 1972 [17 March 1971] 11528/72 Heading C2C Novel compounds I and their acid addition salts in which R is an aliphatic hydrocarbyl group which may be substituted by one or two hydroxyl groups, by one or two acyloxy groups or by an alkoxy, dialkylamino, tetra hydrofuryl or phenyl group and R<SP>1</SP> is hydrogen or an acyl group, are prepared by reaction of a compound of Formula II in which R<SP>11</SP> is hydrogen or a nitro group (those in which R<SP>11</SP> is hydrogen being novel), and Z is an acyloxy group of a sulphonic acid or a bromine or chlorine atom with a primary amine R-NH 2 and a resulting compound not containing a nitro group in the 5-position of the furyl ring is nitrated and, if desired, in the resulting compound any -NH- group or hydroxyl group may be acylated, any acylamino group or acyloxy group may be hydrolysed, or resulting free compound may be converted into an acid addition salt, a resulting salt converted into the corresponding free compound by means of a base, each of the optional steps being carried out before or after nitration. Compounds of Formula I have anti-bacterial action and one or more such compounds form with a suitable carrier a pharmaceutical composition which may be administered orally.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2113529A DE2113529C3 (en) | 1971-03-17 | 1971-03-17 | 2- (5-Nitro-2-furyl) -5- (2-alkylaminoethoxy) pyrimidine compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1391933A true GB1391933A (en) | 1975-04-23 |
Family
ID=5802207
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1152872A Expired GB1391933A (en) | 1971-03-17 | 1972-03-13 | Nitrofuryl-pyrimidine derivatives |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US3846428A (en) |
| AT (1) | AT312589B (en) |
| AU (1) | AU463550B2 (en) |
| BE (1) | BE780879A (en) |
| CA (1) | CA945557A (en) |
| CH (1) | CH575943A5 (en) |
| DD (1) | DD96950A5 (en) |
| DE (1) | DE2113529C3 (en) |
| DK (1) | DK126999B (en) |
| ES (1) | ES400560A1 (en) |
| FR (1) | FR2130327B1 (en) |
| GB (1) | GB1391933A (en) |
| HU (1) | HU163178B (en) |
| IL (1) | IL38962A (en) |
| NL (1) | NL7203650A (en) |
| PL (1) | PL83278B1 (en) |
| SU (1) | SU458130A3 (en) |
| ZA (1) | ZA721689B (en) |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1937629C3 (en) * | 1969-07-19 | 1979-07-26 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Nitrofuryl-aminoalkoxy-pyriinidines |
-
1971
- 1971-03-17 DE DE2113529A patent/DE2113529C3/en not_active Expired
-
1972
- 1972-02-29 DK DK93172AA patent/DK126999B/en unknown
- 1972-03-02 SU SU1754975A patent/SU458130A3/en active
- 1972-03-08 ES ES400560A patent/ES400560A1/en not_active Expired
- 1972-03-08 AU AU39769/72A patent/AU463550B2/en not_active Expired
- 1972-03-12 IL IL38962A patent/IL38962A/en unknown
- 1972-03-13 ZA ZA721689A patent/ZA721689B/en unknown
- 1972-03-13 GB GB1152872A patent/GB1391933A/en not_active Expired
- 1972-03-15 PL PL1972154083A patent/PL83278B1/pl unknown
- 1972-03-15 DD DD161547A patent/DD96950A5/xx unknown
- 1972-03-16 FR FR7209187A patent/FR2130327B1/fr not_active Expired
- 1972-03-16 HU HUSC379A patent/HU163178B/hu unknown
- 1972-03-16 CH CH385372A patent/CH575943A5/xx not_active IP Right Cessation
- 1972-03-16 US US00235426A patent/US3846428A/en not_active Expired - Lifetime
- 1972-03-17 CA CA137,369A patent/CA945557A/en not_active Expired
- 1972-03-17 BE BE780879A patent/BE780879A/en unknown
- 1972-03-17 NL NL7203650A patent/NL7203650A/xx unknown
- 1972-03-17 AT AT230072A patent/AT312589B/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| IL38962A (en) | 1975-10-15 |
| AU3976972A (en) | 1973-09-13 |
| AT312589B (en) | 1974-01-10 |
| DE2113529B2 (en) | 1979-08-02 |
| DK126999B (en) | 1973-09-10 |
| BE780879A (en) | 1972-09-18 |
| ES400560A1 (en) | 1975-02-01 |
| FR2130327A1 (en) | 1972-11-03 |
| DE2113529A1 (en) | 1972-12-14 |
| FR2130327B1 (en) | 1975-04-25 |
| US3846428A (en) | 1974-11-05 |
| AU463550B2 (en) | 1975-07-14 |
| CA945557A (en) | 1974-04-16 |
| NL7203650A (en) | 1972-09-19 |
| DD96950A5 (en) | 1973-04-12 |
| ZA721689B (en) | 1972-12-27 |
| IL38962A0 (en) | 1972-05-30 |
| PL83278B1 (en) | 1975-12-31 |
| DE2113529C3 (en) | 1980-04-30 |
| HU163178B (en) | 1973-06-28 |
| CH575943A5 (en) | 1976-05-31 |
| SU458130A3 (en) | 1975-01-25 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES408565A1 (en) | Cyclic diamine derivatives | |
| GB1307271A (en) | Sulphoximine derivatives and their use in herbicidal compositions | |
| GB1332477A (en) | Basic azo dyes free from sulphonic acid groups their production and use | |
| GB1459571A (en) | Thiophene-2-sulphonamide derivatives and their use as therapeutic agents sheet orienting apparatus | |
| GB1129072A (en) | Benzofuran and indole derivatives | |
| GB925429A (en) | Indole derivatives | |
| GB1411583A (en) | Aminophenyl-substituted alkyl-heterocyclic derivatives and processes for producing them | |
| GB1386150A (en) | 6-acylaminophenyl-4,5-dihydropyridazones | |
| GB1456627A (en) | Pyridobenzodiazepinones | |
| GB1432816A (en) | Pharmaceutical antimycotic compositions medicaments and method | |
| ES266444A1 (en) | Derivatives of cephalosporin c | |
| GB1016071A (en) | New guanidine derivatives and process for preparing the same | |
| GB1462036A (en) | Aminoindane derivatives | |
| GB1391933A (en) | Nitrofuryl-pyrimidine derivatives | |
| GB1293507A (en) | Derivatives of 3-carbamoyl-2-oxazolidinone, and their process of preparation | |
| ES426427A1 (en) | Pharmaceutical compositions comprising nitrocarbostyrils for the treatment of allergic and immunological hypersensitivity | |
| GB1340428A (en) | Benzothiadiazine derivatives their preparation and veterinary and pharmaceutical compositions containing them | |
| GB1320453A (en) | Aromatic diethers | |
| GB1369580A (en) | Tricyclic diphenylamine derivatives | |
| SE7708686L (en) | INTERMEDIATE PRODUCTS AND PROCEDURES FOR THE MANUFACTURE OF IT | |
| GB1161062A (en) | Active Sulphonamides | |
| ES426771A1 (en) | Aminopropanol substituted isochromanones and phthalides | |
| GB1299566A (en) | Bis-basic ethers of 2,6- and 2,7-dihydroxyanthraquinones | |
| GB1371757A (en) | Substituted aminoquinolizinium bromides their preparation and compositions thereof | |
| ES407866A1 (en) | Preparation of n -diethylaminoethyl - 2 - methoxy- 5 - methyl sulphonylbenzamide |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |