GB1383774A - 4-substituted piperidine derivatives - Google Patents
4-substituted piperidine derivativesInfo
- Publication number
- GB1383774A GB1383774A GB3172274A GB3172274A GB1383774A GB 1383774 A GB1383774 A GB 1383774A GB 3172274 A GB3172274 A GB 3172274A GB 3172274 A GB3172274 A GB 3172274A GB 1383774 A GB1383774 A GB 1383774A
- Authority
- GB
- United Kingdom
- Prior art keywords
- compounds
- alkyl
- benzyl
- piperidine derivatives
- hal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- -1 4-substituted piperidine Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 5
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 abstract 3
- 238000006243 chemical reaction Methods 0.000 abstract 2
- SJZKULRDWHPHGG-UHFFFAOYSA-N 1-benzylpiperidin-4-one Chemical compound C1CC(=O)CCN1CC1=CC=CC=C1 SJZKULRDWHPHGG-UHFFFAOYSA-N 0.000 abstract 1
- AOAMQMAEEUONRT-UHFFFAOYSA-N 8-benzyl-1,4-dioxa-8-azaspiro[4.5]decane Chemical compound C=1C=CC=CC=1CN(CC1)CCC21OCCO2 AOAMQMAEEUONRT-UHFFFAOYSA-N 0.000 abstract 1
- 239000002841 Lewis acid Substances 0.000 abstract 1
- 229910010082 LiAlH Inorganic materials 0.000 abstract 1
- 230000010933 acylation Effects 0.000 abstract 1
- 238000005917 acylation reaction Methods 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 238000009903 catalytic hydrogenation reaction Methods 0.000 abstract 1
- 150000007517 lewis acids Chemical class 0.000 abstract 1
- 150000003053 piperidines Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
- C07C51/367—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by introduction of functional groups containing oxygen only in singly bound form
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/48—Oxygen atoms attached in position 4 having an acyclic carbon atom attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR717117509A FR2137149B1 (enExample) | 1971-05-14 | 1971-05-14 | |
| FR7117510A FR2137150B1 (enExample) | 1971-05-14 | 1971-05-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1383774A true GB1383774A (en) | 1974-02-12 |
Family
ID=26216390
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB3172274A Expired GB1383774A (en) | 1971-05-14 | 1972-05-15 | 4-substituted piperidine derivatives |
| GB2277272A Expired GB1383773A (en) | 1971-05-14 | 1972-05-15 | Piperidino-alkyl phenothiazine derivatives |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2277272A Expired GB1383773A (en) | 1971-05-14 | 1972-05-15 | Piperidino-alkyl phenothiazine derivatives |
Country Status (13)
| Country | Link |
|---|---|
| JP (2) | JPS5118958B1 (enExample) |
| AU (1) | AU461649B2 (enExample) |
| BE (1) | BE783411A (enExample) |
| CH (1) | CH553215A (enExample) |
| DE (2) | DE2264903C3 (enExample) |
| DK (1) | DK142318B (enExample) |
| FI (1) | FI55657C (enExample) |
| FR (2) | FR2137149B1 (enExample) |
| GB (2) | GB1383774A (enExample) |
| IL (1) | IL39296A (enExample) |
| NL (1) | NL175824C (enExample) |
| NO (1) | NO135365C (enExample) |
| SE (2) | SE405973B (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0621267A1 (en) * | 1993-04-07 | 1994-10-26 | Shell Internationale Researchmaatschappij B.V. | Spiropiperidine derivatives and their use as fungicides |
| WO2002050050A1 (en) * | 2000-12-19 | 2002-06-27 | Ucb, S.A. | 2-(2-(4-((2r)-2-methyl-3-(10h-phenothiazin-10-yl)propyl)-1-piperazinyl)-ethoxy)ethanol, process for the preparation thereof, pharmaceutical compositions containing said compound and therapeutic uses thereof |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1344593A (fr) * | 1961-11-25 | 1963-11-29 | Boehringer & Soehne Gmbh | Procédé pour la préparation de nouveaux dérivés de l'alcoxy-pipéridine et de leurs sels |
-
1971
- 1971-05-14 FR FR717117509A patent/FR2137149B1/fr not_active Expired
- 1971-05-14 FR FR7117510A patent/FR2137150B1/fr not_active Expired
-
1972
- 1972-04-25 IL IL39296A patent/IL39296A/en unknown
- 1972-04-27 CH CH629072A patent/CH553215A/fr not_active IP Right Cessation
- 1972-05-09 FI FI1305/72A patent/FI55657C/fi active
- 1972-05-09 SE SE7206146A patent/SE405973B/xx unknown
- 1972-05-10 DE DE2264903A patent/DE2264903C3/de not_active Expired
- 1972-05-10 DE DE2222931A patent/DE2222931C3/de not_active Expired
- 1972-05-12 NO NO1690/72A patent/NO135365C/no unknown
- 1972-05-12 AU AU42226/72A patent/AU461649B2/en not_active Expired
- 1972-05-12 BE BE783411A patent/BE783411A/xx not_active IP Right Cessation
- 1972-05-13 JP JP47046917A patent/JPS5118958B1/ja active Pending
- 1972-05-15 NL NLAANVRAGE7206504,A patent/NL175824C/xx not_active IP Right Cessation
- 1972-05-15 DK DK240672AA patent/DK142318B/da not_active IP Right Cessation
- 1972-05-15 GB GB3172274A patent/GB1383774A/en not_active Expired
- 1972-05-15 GB GB2277272A patent/GB1383773A/en not_active Expired
-
1975
- 1975-05-06 SE SE7505250A patent/SE418964B/xx unknown
- 1975-11-25 JP JP50140299A patent/JPS5248988B2/ja not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| FR2137150B1 (enExample) | 1975-01-17 |
| DE2264903B2 (de) | 1981-02-19 |
| NL7206504A (enExample) | 1972-11-16 |
| JPS5191267A (enExample) | 1976-08-10 |
| GB1383773A (en) | 1974-02-12 |
| JPS5248988B2 (enExample) | 1977-12-14 |
| DE2222931A1 (de) | 1972-11-30 |
| CH553215A (fr) | 1974-08-30 |
| NO135365B (enExample) | 1976-12-20 |
| FR2137149A1 (enExample) | 1972-12-29 |
| NO135365C (no) | 1977-03-30 |
| DE2264903C3 (de) | 1981-12-17 |
| NL175824C (nl) | 1985-01-02 |
| FI55657B (fi) | 1979-05-31 |
| IL39296A0 (en) | 1972-06-28 |
| AU461649B2 (en) | 1975-06-05 |
| JPS5118958B1 (enExample) | 1976-06-14 |
| SE405973B (sv) | 1979-01-15 |
| BE783411A (fr) | 1972-11-13 |
| SE418964B (sv) | 1981-07-06 |
| SE7505250L (enExample) | 1975-05-06 |
| DK142318C (enExample) | 1981-03-02 |
| FR2137149B1 (enExample) | 1973-05-11 |
| NL175824B (nl) | 1984-08-01 |
| FR2137150A1 (enExample) | 1972-12-29 |
| DK142318B (da) | 1980-10-13 |
| IL39296A (en) | 1976-03-31 |
| DE2222931B2 (de) | 1977-11-10 |
| DE2264903A1 (de) | 1975-08-28 |
| FI55657C (fi) | 1979-09-10 |
| AU4222672A (en) | 1973-12-06 |
| DE2222931C3 (de) | 1978-07-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |