GB1380243A - Thienobenzazepines processes for their preparation and compositions incorporating them - Google Patents
Thienobenzazepines processes for their preparation and compositions incorporating themInfo
- Publication number
- GB1380243A GB1380243A GB965472A GB965472A GB1380243A GB 1380243 A GB1380243 A GB 1380243A GB 965472 A GB965472 A GB 965472A GB 965472 A GB965472 A GB 965472A GB 1380243 A GB1380243 A GB 1380243A
- Authority
- GB
- United Kingdom
- Prior art keywords
- group
- hydrogen atom
- alkyl
- together form
- corresponding compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000000203 mixture Substances 0.000 title 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 12
- 125000000217 alkyl group Chemical group 0.000 abstract 11
- 150000001875 compounds Chemical class 0.000 abstract 9
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 5
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 5
- 125000004414 alkyl thio group Chemical group 0.000 abstract 4
- 239000002253 acid Substances 0.000 abstract 3
- 125000003545 alkoxy group Chemical group 0.000 abstract 3
- 150000008038 benzoazepines Chemical class 0.000 abstract 3
- 238000006243 chemical reaction Methods 0.000 abstract 3
- 125000002947 alkylene group Chemical group 0.000 abstract 2
- 125000005530 alkylenedioxy group Chemical group 0.000 abstract 2
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 2
- 125000004429 atom Chemical group 0.000 abstract 2
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Chemical compound BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- -1 sulphamoyl Chemical group 0.000 abstract 2
- 125000006557 (C2-C5) alkylene group Chemical group 0.000 abstract 1
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical group [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 abstract 1
- KZBUYRJDOAKODT-UHFFFAOYSA-N Chlorine Chemical compound ClCl KZBUYRJDOAKODT-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 238000005903 acid hydrolysis reaction Methods 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 125000004442 acylamino group Chemical group 0.000 abstract 1
- 125000004423 acyloxy group Chemical group 0.000 abstract 1
- 238000005904 alkaline hydrolysis reaction Methods 0.000 abstract 1
- 230000029936 alkylation Effects 0.000 abstract 1
- 238000005804 alkylation reaction Methods 0.000 abstract 1
- 230000001430 anti-depressive effect Effects 0.000 abstract 1
- 239000000935 antidepressant agent Substances 0.000 abstract 1
- 229940005513 antidepressants Drugs 0.000 abstract 1
- 229910052794 bromium Inorganic materials 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- 230000018044 dehydration Effects 0.000 abstract 1
- 238000006297 dehydration reaction Methods 0.000 abstract 1
- 125000004663 dialkyl amino group Chemical group 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000005842 heteroatom Chemical group 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 238000007327 hydrogenolysis reaction Methods 0.000 abstract 1
- 229910052740 iodine Inorganic materials 0.000 abstract 1
- 125000002524 organometallic group Chemical group 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000005415 substituted alkoxy group Chemical group 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AT168572T | 1950-01-10 | ||
| FR7106917A FR2128030A1 (en) | 1971-03-01 | 1971-03-01 | 4-(alkylaminoalkyl) (4h) thieno (3,2-b) (f) benzazepines |
| AT1019673A AT322558B (de) | 1950-01-10 | 1972-03-01 | Verfahren zur herstellung von neuen 4-(aminodalkyl)-9,10 dihydro (4h)-thieno (3,2-8) (f) benzazepinen sowei von ihren salzen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1380243A true GB1380243A (en) | 1975-01-08 |
Family
ID=27151165
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB965472A Expired GB1380243A (en) | 1950-01-10 | 1972-03-01 | Thienobenzazepines processes for their preparation and compositions incorporating them |
| GB5767773A Expired GB1380244A (en) | 1950-01-10 | 1972-03-01 | Thienobenzazepines and processes for their preparation |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB5767773A Expired GB1380244A (en) | 1950-01-10 | 1972-03-01 | Thienobenzazepines and processes for their preparation |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US3787445A (en:Method) |
| JP (1) | JPS5323839B1 (en:Method) |
| AR (2) | AR204904A1 (en:Method) |
| AT (2) | AT321921B (en:Method) |
| AU (1) | AU463890B2 (en:Method) |
| BE (1) | BE779965A (en:Method) |
| CA (1) | CA977750A (en:Method) |
| CH (2) | CH583237A5 (en:Method) |
| DD (2) | DD103444A5 (en:Method) |
| DE (1) | DE2209844C3 (en:Method) |
| DK (1) | DK136071B (en:Method) |
| ES (3) | ES400256A1 (en:Method) |
| FI (1) | FI52585C (en:Method) |
| GB (2) | GB1380243A (en:Method) |
| HU (2) | HU163926B (en:Method) |
| IL (1) | IL38795A (en:Method) |
| NL (1) | NL165168C (en:Method) |
| SE (2) | SE385372B (en:Method) |
| SU (2) | SU504486A3 (en:Method) |
| ZA (1) | ZA721111B (en:Method) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2316956A1 (fr) * | 1975-07-10 | 1977-02-04 | Roussel Uclaf | Nouveaux derives des 4h-thieno-3,2-b-1-benzazepines et leurs sels, procede de preparation et application a titre de medicaments |
-
1972
- 1972-01-01 AR AR244301A patent/AR204904A1/es active
- 1972-01-01 AR AR244302A patent/AR206873A1/es active
- 1972-02-16 CH CH1067075A patent/CH583237A5/xx not_active IP Right Cessation
- 1972-02-16 CH CH1200073A patent/CH565191A5/xx not_active IP Right Cessation
- 1972-02-18 IL IL38795A patent/IL38795A/xx unknown
- 1972-02-21 ZA ZA721111A patent/ZA721111B/xx unknown
- 1972-02-28 US US00230124A patent/US3787445A/en not_active Expired - Lifetime
- 1972-02-29 HU HURO645A patent/HU163926B/hu unknown
- 1972-02-29 CA CA135,883A patent/CA977750A/en not_active Expired
- 1972-02-29 HU HURO685A patent/HU164501B/hu unknown
- 1972-02-29 ES ES400256A patent/ES400256A1/es not_active Expired
- 1972-02-29 DD DD161188A patent/DD103444A5/xx unknown
- 1972-02-29 DD DD172379*A patent/DD106043A5/xx unknown
- 1972-02-29 BE BE779965A patent/BE779965A/xx unknown
- 1972-02-29 FI FI720529A patent/FI52585C/fi active
- 1972-02-29 AU AU39460/72A patent/AU463890B2/en not_active Expired
- 1972-02-29 SE SE7202535A patent/SE385372B/xx unknown
- 1972-03-01 GB GB965472A patent/GB1380243A/en not_active Expired
- 1972-03-01 DK DK93972AA patent/DK136071B/da unknown
- 1972-03-01 DE DE2209844A patent/DE2209844C3/de not_active Expired
- 1972-03-01 JP JP2069372A patent/JPS5323839B1/ja active Pending
- 1972-03-01 AT AT168572A patent/AT321921B/de not_active IP Right Cessation
- 1972-03-01 SU SU1753759A patent/SU504486A3/ru active
- 1972-03-01 NL NL7202673.A patent/NL165168C/xx not_active IP Right Cessation
- 1972-03-01 AT AT1019673A patent/AT322558B/de not_active IP Right Cessation
- 1972-03-01 GB GB5767773A patent/GB1380244A/en not_active Expired
-
1973
- 1973-08-28 SU SU1951903A patent/SU559648A3/ru active
- 1973-09-15 ES ES418786A patent/ES418786A1/es not_active Expired
- 1973-09-15 ES ES418785A patent/ES418785A1/es not_active Expired
-
1975
- 1975-01-30 SE SE7501035A patent/SE416471B/xx unknown
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |