GB1377313A - Process for purifying phenylalanine derivatives - Google Patents
Process for purifying phenylalanine derivativesInfo
- Publication number
- GB1377313A GB1377313A GB2292473A GB2292473A GB1377313A GB 1377313 A GB1377313 A GB 1377313A GB 2292473 A GB2292473 A GB 2292473A GB 2292473 A GB2292473 A GB 2292473A GB 1377313 A GB1377313 A GB 1377313A
- Authority
- GB
- United Kingdom
- Prior art keywords
- aspartyl
- alpha
- resin
- phenylalanine
- contaminated
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000002993 phenylalanine derivatives Chemical class 0.000 title 1
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 abstract 3
- 239000011347 resin Substances 0.000 abstract 3
- 229920005989 resin Polymers 0.000 abstract 3
- 125000005907 alkyl ester group Chemical group 0.000 abstract 2
- YZQCXOFQZKCETR-UWVGGRQHSA-N Asp-Phe Chemical compound OC(=O)C[C@H](N)C(=O)N[C@H](C(O)=O)CC1=CC=CC=C1 YZQCXOFQZKCETR-UWVGGRQHSA-N 0.000 abstract 1
- BDAGIHXWWSANSR-UHFFFAOYSA-N Formic acid Chemical class OC=O BDAGIHXWWSANSR-UHFFFAOYSA-N 0.000 abstract 1
- 239000004793 Polystyrene Substances 0.000 abstract 1
- 239000003957 anion exchange resin Substances 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 229920002223 polystyrene Polymers 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06104—Dipeptides with the first amino acid being acidic
- C07K5/06113—Asp- or Asn-amino acid
- C07K5/06121—Asp- or Asn-amino acid the second amino acid being aromatic or cycloaliphatic
- C07K5/0613—Aspartame
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
- A23L27/30—Artificial sweetening agents
- A23L27/31—Artificial sweetening agents containing amino acids, nucleotides, peptides or derivatives
- A23L27/32—Artificial sweetening agents containing amino acids, nucleotides, peptides or derivatives containing dipeptides or derivatives
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/801—Peptide sweetners
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Nutrition Science (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP47051985A JPS5235660B2 (OSRAM) | 1972-05-25 | 1972-05-25 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1377313A true GB1377313A (en) | 1974-12-11 |
Family
ID=12902137
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2292473A Expired GB1377313A (en) | 1972-05-25 | 1973-05-14 | Process for purifying phenylalanine derivatives |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US3833554A (OSRAM) |
| JP (1) | JPS5235660B2 (OSRAM) |
| CA (1) | CA1009649A (OSRAM) |
| CH (1) | CH562777A5 (OSRAM) |
| DE (1) | DE2326897C2 (OSRAM) |
| FR (1) | FR2185630B1 (OSRAM) |
| GB (1) | GB1377313A (OSRAM) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS50144223A (OSRAM) * | 1974-05-13 | 1975-11-20 | ||
| JPS5248217A (en) * | 1975-10-14 | 1977-04-16 | Nippon Soil Eng | Method of and apparatus for improving subsoil with pressed impregnation |
| US4111925A (en) * | 1977-10-14 | 1978-09-05 | Monsanto Company | Hydrolysis of esters of α-L-aspartyl-L-phenylalanine |
| JPS5470161U (OSRAM) * | 1977-10-28 | 1979-05-18 | ||
| JPS6049199B2 (ja) * | 1979-04-10 | 1985-10-31 | 東ソー株式会社 | α−Ｌ−アスパルチル−Ｌ−フエニルアラニン低級アルキルエステルの精製法 |
| FR2516077A1 (fr) * | 1981-11-06 | 1983-05-13 | Human Pharm Sa Laboratoires | Procede de preparation de l'ester-methylique de l'a-aspartyl phenylalanine |
| JPS58177952A (ja) * | 1982-04-12 | 1983-10-18 | Ajinomoto Co Inc | Ｌ−α−アスパルチル−Ｌ−フエニルアラニンメチルエステルの晶析法 |
| JPH0680074B2 (ja) * | 1985-07-01 | 1994-10-12 | 味の素株式会社 | Ｎ―ホルミル―Ｌ―α―アスパルチル―Ｌ―フェニルアラニンの製法 |
| JPH0657719B2 (ja) * | 1986-06-03 | 1994-08-03 | 味の素株式会社 | α−Ｌ−アスパルチル−Ｌ−フエニルアラニンメチルエステルの回収方法 |
| JP2728936B2 (ja) * | 1989-06-14 | 1998-03-18 | 三井東圧化学株式会社 | α―Ｌ―アスパルチル―Ｌ―スェニルアラニンメチルエステルの製造方法 |
| JPH05286994A (ja) * | 1992-04-13 | 1993-11-02 | Tosoh Corp | α−Ｌ−アスパルチル−Ｌ−フェニルアラニンメチルエステルの晶析法 |
| JPH06331294A (ja) * | 1993-05-25 | 1994-11-29 | Showa Alum Corp | オイルクーラ |
| JPH11171895A (ja) | 1997-12-11 | 1999-06-29 | Ajinomoto Co Inc | アスパルテームとアスパルテーム誘導体の分離精製方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS4941425B1 (OSRAM) * | 1970-10-26 | 1974-11-08 |
-
1972
- 1972-05-25 JP JP47051985A patent/JPS5235660B2/ja not_active Expired
-
1973
- 1973-05-14 GB GB2292473A patent/GB1377313A/en not_active Expired
- 1973-05-16 US US00360673A patent/US3833554A/en not_active Expired - Lifetime
- 1973-05-22 CA CA171,920A patent/CA1009649A/en not_active Expired
- 1973-05-24 CH CH746073A patent/CH562777A5/xx not_active IP Right Cessation
- 1973-05-24 FR FR7318916A patent/FR2185630B1/fr not_active Expired
- 1973-05-25 DE DE2326897A patent/DE2326897C2/de not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DE2326897A1 (de) | 1973-12-06 |
| JPS497245A (OSRAM) | 1974-01-22 |
| CA1009649A (en) | 1977-05-03 |
| FR2185630A1 (OSRAM) | 1974-01-04 |
| CH562777A5 (OSRAM) | 1975-06-13 |
| FR2185630B1 (OSRAM) | 1978-02-10 |
| JPS5235660B2 (OSRAM) | 1977-09-10 |
| DE2326897C2 (de) | 1982-06-09 |
| US3833554A (en) | 1974-09-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PE20 | Patent expired after termination of 20 years |
Effective date: 19930513 |