GB1368716A - Cephalosporin compounds - Google Patents
Cephalosporin compoundsInfo
- Publication number
- GB1368716A GB1368716A GB3547572A GB3547572A GB1368716A GB 1368716 A GB1368716 A GB 1368716A GB 3547572 A GB3547572 A GB 3547572A GB 3547572 A GB3547572 A GB 3547572A GB 1368716 A GB1368716 A GB 1368716A
- Authority
- GB
- United Kingdom
- Prior art keywords
- group
- acid
- heterocyclic
- formula
- acylating
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229940124587 cephalosporin Drugs 0.000 title abstract 4
- 229930186147 Cephalosporin Natural products 0.000 title abstract 2
- -1 Cephalosporin compounds Chemical class 0.000 title abstract 2
- 239000002253 acid Substances 0.000 abstract 4
- 125000000623 heterocyclic group Chemical group 0.000 abstract 4
- 150000003839 salts Chemical class 0.000 abstract 3
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 abstract 2
- 125000004423 acyloxy group Chemical group 0.000 abstract 2
- 150000002148 esters Chemical class 0.000 abstract 2
- 229910052757 nitrogen Inorganic materials 0.000 abstract 2
- 230000000269 nucleophilic effect Effects 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 125000003396 thiol group Chemical group [H]S* 0.000 abstract 2
- UGUHFDPGDQDVGX-UHFFFAOYSA-N 1,2,3-thiadiazole Chemical group C1=CSN=N1 UGUHFDPGDQDVGX-UHFFFAOYSA-N 0.000 abstract 1
- 241000894006 Bacteria Species 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- CZPWVGJYEJSRLH-UHFFFAOYSA-N Pyrimidine Chemical compound C1=CN=CN=C1 CZPWVGJYEJSRLH-UHFFFAOYSA-N 0.000 abstract 1
- FZWLAAWBMGSTSO-UHFFFAOYSA-N Thiazole Chemical compound C1=CSC=N1 FZWLAAWBMGSTSO-UHFFFAOYSA-N 0.000 abstract 1
- 125000003668 acetyloxy group Chemical group [H]C([H])([H])C(=O)O[*] 0.000 abstract 1
- 150000008065 acid anhydrides Chemical class 0.000 abstract 1
- 125000001931 aliphatic group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 150000001540 azides Chemical class 0.000 abstract 1
- 230000003115 biocidal effect Effects 0.000 abstract 1
- 150000001780 cephalosporins Chemical class 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 238000006073 displacement reaction Methods 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 150000004820 halides Chemical class 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000005842 heteroatom Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004356 hydroxy functional group Chemical group O* 0.000 abstract 1
- 125000002950 monocyclic group Chemical group 0.000 abstract 1
- 125000001624 naphthyl group Chemical group 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000002798 polar solvent Substances 0.000 abstract 1
- ZNNZYHKDIALBAK-UHFFFAOYSA-M potassium thiocyanate Chemical compound [K+].[S-]C#N ZNNZYHKDIALBAK-UHFFFAOYSA-M 0.000 abstract 1
- 229940116357 potassium thiocyanate Drugs 0.000 abstract 1
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 abstract 1
- 239000000376 reactant Substances 0.000 abstract 1
- 229920006395 saturated elastomer Polymers 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
- 150000003536 tetrazoles Chemical class 0.000 abstract 1
- 125000001544 thienyl group Chemical group 0.000 abstract 1
- 125000003944 tolyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/36—Methylene radicals, substituted by sulfur atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP5689571A JPS5442994B1 (en:Method) | 1971-07-29 | 1971-07-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1368716A true GB1368716A (en) | 1974-10-02 |
Family
ID=13040164
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB3547572A Expired GB1368716A (en) | 1971-07-29 | 1972-07-28 | Cephalosporin compounds |
Country Status (14)
| Country | Link |
|---|---|
| JP (1) | JPS5442994B1 (en:Method) |
| AT (1) | AT318144B (en:Method) |
| AU (1) | AU463668B2 (en:Method) |
| CA (1) | CA1010443A (en:Method) |
| CH (1) | CH592680A5 (en:Method) |
| DE (1) | DE2236422C2 (en:Method) |
| DK (1) | DK144177C (en:Method) |
| ES (1) | ES405281A1 (en:Method) |
| FR (1) | FR2147311B1 (en:Method) |
| GB (1) | GB1368716A (en:Method) |
| HU (1) | HU164342B (en:Method) |
| NL (1) | NL177406C (en:Method) |
| NO (1) | NO142913C (en:Method) |
| SE (1) | SE412913B (en:Method) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS51115493A (en) * | 1975-03-18 | 1976-10-12 | Smithkline Corp | Novel cephalosporine compound |
-
1971
- 1971-07-29 JP JP5689571A patent/JPS5442994B1/ja active Pending
-
1972
- 1972-07-24 AU AU44892/72A patent/AU463668B2/en not_active Expired
- 1972-07-25 DE DE19722236422 patent/DE2236422C2/de not_active Expired
- 1972-07-26 NO NO267972A patent/NO142913C/no unknown
- 1972-07-27 NL NL7210382A patent/NL177406C/xx not_active IP Right Cessation
- 1972-07-28 HU HUTA001197 patent/HU164342B/hu unknown
- 1972-07-28 AT AT654272A patent/AT318144B/de not_active IP Right Cessation
- 1972-07-28 DK DK376572A patent/DK144177C/da active
- 1972-07-28 SE SE989272A patent/SE412913B/xx unknown
- 1972-07-28 CH CH1133572A patent/CH592680A5/xx not_active IP Right Cessation
- 1972-07-28 ES ES405281A patent/ES405281A1/es not_active Expired
- 1972-07-28 FR FR7227387A patent/FR2147311B1/fr not_active Expired
- 1972-07-28 GB GB3547572A patent/GB1368716A/en not_active Expired
- 1972-07-28 CA CA148,179A patent/CA1010443A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| AT318144B (de) | 1974-09-25 |
| FR2147311A1 (en:Method) | 1973-03-09 |
| NO142913C (no) | 1980-11-12 |
| AU463668B2 (en) | 1975-07-31 |
| DE2236422C2 (de) | 1981-12-10 |
| NL7210382A (en:Method) | 1973-01-31 |
| DK144177C (da) | 1982-08-02 |
| ES405281A1 (es) | 1975-07-01 |
| FR2147311B1 (en:Method) | 1976-03-05 |
| DE2236422A1 (de) | 1973-02-22 |
| JPS5442994B1 (en:Method) | 1979-12-17 |
| NL177406B (nl) | 1985-04-16 |
| DK144177B (da) | 1982-01-04 |
| NL177406C (nl) | 1985-09-16 |
| CA1010443A (en) | 1977-05-17 |
| CH592680A5 (en:Method) | 1977-10-31 |
| AU4489272A (en) | 1974-01-31 |
| NO142913B (no) | 1980-08-04 |
| HU164342B (en:Method) | 1974-01-28 |
| SE412913B (sv) | 1980-03-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed |