GB1357737A - Sustained release pharmaceutical compositions - Google Patents
Sustained release pharmaceutical compositionsInfo
- Publication number
- GB1357737A GB1357737A GB4816770A GB4816770A GB1357737A GB 1357737 A GB1357737 A GB 1357737A GB 4816770 A GB4816770 A GB 4816770A GB 4816770 A GB4816770 A GB 4816770A GB 1357737 A GB1357737 A GB 1357737A
- Authority
- GB
- United Kingdom
- Prior art keywords
- asa
- polysiloxane
- cellulose
- toluene
- ester
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000013268 sustained release Methods 0.000 title abstract 3
- 239000012730 sustained-release form Substances 0.000 title abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 abstract 9
- BSYNRYMUTXBXSQ-UHFFFAOYSA-N Aspirin Chemical compound CC(=O)OC1=CC=CC=C1C(O)=O BSYNRYMUTXBXSQ-UHFFFAOYSA-N 0.000 abstract 6
- YMWUJEATGCHHMB-UHFFFAOYSA-N Dichloromethane Chemical compound ClCCl YMWUJEATGCHHMB-UHFFFAOYSA-N 0.000 abstract 6
- 229960001138 acetylsalicylic acid Drugs 0.000 abstract 6
- -1 polysiloxane Polymers 0.000 abstract 6
- 229920002678 cellulose Polymers 0.000 abstract 5
- 229920001296 polysiloxane Polymers 0.000 abstract 5
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 abstract 3
- 229920003086 cellulose ether Polymers 0.000 abstract 3
- 150000002148 esters Chemical class 0.000 abstract 3
- 239000007788 liquid Substances 0.000 abstract 3
- 150000003839 salts Chemical class 0.000 abstract 3
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 abstract 2
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 abstract 2
- 239000001913 cellulose Substances 0.000 abstract 2
- 239000011159 matrix material Substances 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- VZGDMQKNWNREIO-UHFFFAOYSA-N tetrachloromethane Chemical compound ClC(Cl)(Cl)Cl VZGDMQKNWNREIO-UHFFFAOYSA-N 0.000 abstract 2
- 239000001856 Ethyl cellulose Substances 0.000 abstract 1
- ZZSNKZQZMQGXPY-UHFFFAOYSA-N Ethyl cellulose Chemical compound CCOCC1OC(OC)C(OCC)C(OCC)C1OC1C(O)C(O)C(OC)C(CO)O1 ZZSNKZQZMQGXPY-UHFFFAOYSA-N 0.000 abstract 1
- 239000004471 Glycine Substances 0.000 abstract 1
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 abstract 1
- 150000004945 aromatic hydrocarbons Chemical class 0.000 abstract 1
- 239000002775 capsule Substances 0.000 abstract 1
- 239000004202 carbamide Substances 0.000 abstract 1
- 239000004205 dimethyl polysiloxane Substances 0.000 abstract 1
- 235000013870 dimethyl polysiloxane Nutrition 0.000 abstract 1
- 239000008298 dragée Substances 0.000 abstract 1
- 229920001249 ethyl cellulose Polymers 0.000 abstract 1
- 235000019325 ethyl cellulose Nutrition 0.000 abstract 1
- 239000008187 granular material Substances 0.000 abstract 1
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB4816770A GB1357737A (en) | 1970-10-09 | 1970-10-09 | Sustained release pharmaceutical compositions |
| CA123,851A CA974883A (en) | 1970-10-09 | 1971-09-28 | Acetylsalicylic acid sustained release preparations |
| US00184634A US3853988A (en) | 1970-10-09 | 1971-09-28 | Sustained released pharmaceutical compositions |
| ES395533A ES395533A1 (es) | 1970-10-09 | 1971-09-29 | Un procedimiento para preparar composiciones farmaceuticas de liberacion prolongada a base de acido acetilsalicilico. |
| FR7135618A FR2110314B1 (enExample) | 1970-10-09 | 1971-10-04 | |
| DE19712149699 DE2149699A1 (de) | 1970-10-09 | 1971-10-05 | Pharmazeutische Zusammensetzungen mit verzoegerter Wirkstoff-Freisetzung |
| DK487571AA DK129434B (da) | 1970-10-09 | 1971-10-07 | Fremgangsmåde til fremstilling af et farmaceutisk præparat af acetylsalicylsyre som virksomt stof samt polysiloxan og en celluloseæter eller ester og med gradvis frigivelse af det virksomme stof. |
| SE7112796A SE382560B (sv) | 1970-10-09 | 1971-10-08 | Forfarande for framstellning av acetylsalicylsyra inklusive farmaceutiskt godtagbara salter och komplex derav innehallande farmaceutiska kompositioner med fordrojd frigoring |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB4816770A GB1357737A (en) | 1970-10-09 | 1970-10-09 | Sustained release pharmaceutical compositions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1357737A true GB1357737A (en) | 1974-06-26 |
Family
ID=10447626
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB4816770A Expired GB1357737A (en) | 1970-10-09 | 1970-10-09 | Sustained release pharmaceutical compositions |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US3853988A (enExample) |
| CA (1) | CA974883A (enExample) |
| DE (1) | DE2149699A1 (enExample) |
| DK (1) | DK129434B (enExample) |
| ES (1) | ES395533A1 (enExample) |
| FR (1) | FR2110314B1 (enExample) |
| GB (1) | GB1357737A (enExample) |
| SE (1) | SE382560B (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4167558A (en) | 1976-02-13 | 1979-09-11 | Hoffmann-La Roche Inc. | Novel sustained release tablet formulations |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS51123814A (en) * | 1975-04-22 | 1976-10-28 | Shin Etsu Chem Co Ltd | A process for preparing gradually releasable solid medicines |
| DE2902414A1 (de) * | 1979-01-23 | 1980-08-07 | Hoechst Ag | Depotkoerper auf basis silicon- kautschuk sowie verfahren zu seiner herstellung |
| FR2514261B1 (fr) * | 1981-10-08 | 1986-08-22 | Aec Chim Organ Biolog | Nouvelle composition pour l'enrobage des aliments et des medicaments et granules ainsi enrobes |
| DE3508097A1 (de) * | 1984-07-21 | 1986-02-06 | Hoechst Ag, 6230 Frankfurt | Kombinationspraeparat aus xanthinderivaten und o-acetylsalicylsaeure bzw. deren pharmakologisch vertraeglichen salzen und dessen verwendung |
| FR2653338B1 (fr) * | 1989-10-23 | 1994-06-10 | Dow Corning Sa | Formulation pour des pansements a liberation prolongee de medicament et son utilisation. |
| DE4409357C2 (de) * | 1994-03-18 | 1996-10-17 | Upmeyer Hans Juergen | Verwendung von Dimeticon zur Eradikation von Heliobacter pylori |
| CZ300696A3 (en) * | 1994-03-18 | 1997-09-17 | Alfred Schmidt | USE OF DEMETICON FOR PREPARING A PHARMACEUTICAL COMPOSITION FOR LOCAL AND ANTIBACTERIAL THERAPY AND/OR PREVENTION AND THERAPY OF SYNDROMES AND INFECTIOUS DISEASES CONNECTED WITH HELIOBACTER PYLORI (Hp) |
| US5965161A (en) | 1994-11-04 | 1999-10-12 | Euro-Celtique, S.A. | Extruded multi-particulates |
| WO1997002019A1 (en) * | 1995-06-30 | 1997-01-23 | Baylor University | Polyester/carboxylic acid composite materials |
| US20110039807A1 (en) * | 2009-08-13 | 2011-02-17 | Kim Hyoung-Chun | Anti-parkinsonian compound acetylsalicylic acid maltol ester |
| WO2014014753A1 (en) * | 2012-07-17 | 2014-01-23 | Dow Global Technologies Llc | Composition comprising an organic liquid diluent and a cellulose ether of very low viscosity |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2805977A (en) * | 1955-01-04 | 1957-09-10 | Smith Kline French Lab | Sustained release pharmaceutical preparation |
| GB971486A (en) * | 1960-04-01 | 1964-09-30 | Rech S Pharma Et Scient | Therapeutic compositions comprising aspirin and polysiloxanes |
| US3133863A (en) * | 1961-03-10 | 1964-05-19 | Strong Cobb Arner Inc | Sustained release therapeutic tablet compositions comprising organic solvent-gelled gums |
| AU407324B2 (en) * | 1962-05-01 | 1970-10-28 | Smith, Kline & French Laboratories | Powdered silicone products and processes |
| US3501571A (en) * | 1965-12-06 | 1970-03-17 | Smithkline Corp | Novel silicone compositions and method of preparing same |
| US3518344A (en) * | 1967-10-02 | 1970-06-30 | Miles Lab | Tableting lubricant |
-
1970
- 1970-10-09 GB GB4816770A patent/GB1357737A/en not_active Expired
-
1971
- 1971-09-28 CA CA123,851A patent/CA974883A/en not_active Expired
- 1971-09-28 US US00184634A patent/US3853988A/en not_active Expired - Lifetime
- 1971-09-29 ES ES395533A patent/ES395533A1/es not_active Expired
- 1971-10-04 FR FR7135618A patent/FR2110314B1/fr not_active Expired
- 1971-10-05 DE DE19712149699 patent/DE2149699A1/de active Pending
- 1971-10-07 DK DK487571AA patent/DK129434B/da unknown
- 1971-10-08 SE SE7112796A patent/SE382560B/xx unknown
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4167558A (en) | 1976-02-13 | 1979-09-11 | Hoffmann-La Roche Inc. | Novel sustained release tablet formulations |
Also Published As
| Publication number | Publication date |
|---|---|
| US3853988A (en) | 1974-12-10 |
| FR2110314A1 (enExample) | 1972-06-02 |
| DE2149699A1 (de) | 1972-04-13 |
| FR2110314B1 (enExample) | 1975-06-06 |
| CA974883A (en) | 1975-09-23 |
| DK129434B (da) | 1974-10-14 |
| SE382560B (sv) | 1976-02-09 |
| ES395533A1 (es) | 1974-10-16 |
| DK129434C (enExample) | 1975-03-10 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GB1357737A (en) | Sustained release pharmaceutical compositions | |
| AR065827A2 (es) | Formas de dosificacion de liberacion sostenida de sertralina, sales de sertralina, composicion farmaceutica, procedimiento y preparacion y su uso en terapia | |
| JPS63174922A (ja) | 有効成分の投与のための医薬製剤 | |
| GB1298494A (en) | Phenylethanolamine derivatives | |
| US3966923A (en) | Medicaments intended for the prevention and treatment of ischemic disturbances | |
| GB1015787A (en) | Tris-(p-methoxyphenyl)ethylene derivatives | |
| IL102949A (en) | Substituted mandelic acid derivatives their preparation and pharmaceutical compositions containing them | |
| US3144387A (en) | Anti-inflammatory compositions | |
| US4975423A (en) | Inhibition of tumor development | |
| EP0302421A2 (en) | Alpha-carotene for inhibiting the growth of cancer cells | |
| GB1276089A (en) | Pharmaceutical preparations | |
| ES247237A1 (es) | UN MÉTODO PARA LA PREPARACION DE GRáNULOS DE ACCIoN PROLONGADA | |
| US3362879A (en) | Tyrosine tranquilizing compositions and methods of treatment | |
| US3155577A (en) | Tasteless dioctylsulfosuccinate composition and method of making same | |
| US4241055A (en) | Derivatives of aspirin | |
| US3242049A (en) | Process for making enterically useful complex of spiramycin and product thereof | |
| FI84697B (fi) | Foerfarande foer framstaellning av en farmakologisk komposition med derivat av peroxidifosforsyra. | |
| GB1442159A (en) | Pharmaceutical compositions containing paracetamol | |
| GB1460325A (en) | Pharmaceutical composition intended for relieving pain and producing analgesia | |
| IE35419L (en) | Pharmaceutical composition containing cyclobenzaprine | |
| GB1435923A (en) | Pharmaceutical compositions for treating vascular diseases | |
| IE34648L (en) | Pharmaceutical composition containing garcinia acid | |
| US3887706A (en) | N6-(3-Chlorobuten-2-yl)-adenosines as anti-inflammatory agents | |
| JPS5862114A (ja) | 血小板の凝集を防止するための製薬組成物 | |
| NL8003299A (nl) | Middel voor de bestrijding van de groei van kanker- cellen en werkwijze ter bereiding daarvan. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PLNP | Patent lapsed through nonpayment of renewal fees |